List of works - Tobias Goldmann

A comparative evaluation of NB30, NB54 and PTC124 in translational read-through efficacy for treatment of an USH1C nonsense mutation

scientific article

A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa.

scientific article published on 10 December 2010

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

scientific article published on 29 September 2013

Adeno-associated virus-mediated rhodopsin replacement provides therapeutic benefit in mice with a targeted disruption of the rhodopsin gene.

scientific article published in March 2010

Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation

scientific article

Expression and subcellular localization of<i>USH1C</i>/harmonin in human retina provides insights into pathomechanisms and therapy

scientific article published in 2022

Fine-tuning of type I IFN-signaling in microglia--implications for homeostasis, CNS autoimmunity and interferonopathies

scientific article published on 19 September 2015

Gene repair of an Usher syndrome causing mutation by zinc-finger nuclease mediated homologous recombination.

scientific article

Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia

scientific article published on 01 March 2020

Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome

scientific article published on 20 June 2016

Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia

scientific article

Light-dependent translocation of arrestin in rod photoreceptors is signaled through a phospholipase C cascade and requires ATP.

scientific article published on March 2010

Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling

scientific article published on 08 February 2021

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

scientific article

Microglia fuel the learning brain

scientific article published on 11 March 2014

Occurrence of Retinal Ganglion Cell Loss via Autophagy and Apoptotic Pathways in an Autoimmune Glaucoma Model

scientific article published on 03 February 2020

Origin, fate and dynamics of macrophages at central nervous system interfaces

scientific article

PTC124-mediated translational readthrough of a nonsense mutation causing Usher syndrome type 1C.

scientific article published on 25 March 2011

Photoreceptor vitality in organotypic cultures of mature vertebrate retinas validated by light-dependent molecular movements.

scientific article published on 18 September 2006

Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance

scientific article

Successful subretinal delivery and monitoring of MicroBeads in mice

scientific article

Suppression and replacement gene therapy for autosomal dominant disease in a murine model of dominant retinitis pigmentosa

scientific article

The translocation of signaling molecules in dark adapting mammalian rod photoreceptor cells is dependent on the cytoskeleton

scientific article published in October 2008

USP18 lack in microglia causes destructive interferonopathy of the mouse brain

scientific article published on 20 April 2015

List of works by Tobias Goldmann

A comparative evaluation of NB30, NB54 and PTC124 in translational read-through efficacy for treatment of an USH1C nonsense mutation

A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa.

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

Adeno-associated virus-mediated rhodopsin replacement provides therapeutic benefit in mice with a targeted disruption of the rhodopsin gene.

Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation

Expression and subcellular localization of<i>USH1C</i>/harmonin in human retina provides insights into pathomechanisms and therapy

Fine-tuning of type I IFN-signaling in microglia--implications for homeostasis, CNS autoimmunity and interferonopathies

Gene repair of an Usher syndrome causing mutation by zinc-finger nuclease mediated homologous recombination.

Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia

Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome

Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia

Light-dependent translocation of arrestin in rod photoreceptors is signaled through a phospholipase C cascade and requires ATP.

Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

Microglia fuel the learning brain

Occurrence of Retinal Ganglion Cell Loss via Autophagy and Apoptotic Pathways in an Autoimmune Glaucoma Model

Origin, fate and dynamics of macrophages at central nervous system interfaces

PTC124-mediated translational readthrough of a nonsense mutation causing Usher syndrome type 1C.

Photoreceptor vitality in organotypic cultures of mature vertebrate retinas validated by light-dependent molecular movements.

Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance

Successful subretinal delivery and monitoring of MicroBeads in mice

Suppression and replacement gene therapy for autosomal dominant disease in a murine model of dominant retinitis pigmentosa

The translocation of signaling molecules in dark adapting mammalian rod photoreceptor cells is dependent on the cytoskeleton

USP18 lack in microglia causes destructive interferonopathy of the mouse brain