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List of works by Anthony A Holder

<i>Plasmodium</i> SAS4: basal body component of male cell which is dispensable for parasite transmission

scientific article published on 12 May 2022

A 22 kDa protein associated with the Plasmodium falciparum merozoite surface protein-1 complex

scientific article published on 01 October 1996

A Plasmodium chabaudi protein contains a repetitive region with a predicted spectrin-like structure1Note: Nucleotide sequence data reported in this paper are available in the EMBL, GenBank™ and DDJB databases under the accession number U43145.1

scientific article published in August 1998

A bacterial phosphatase-like enzyme of the malaria parasite Plasmodium falciparum possesses tyrosine phosphatase activity and is implicated in the regulation of band 3 dynamics during parasite invasion

scientific article published on 3 July 2013

A comprehensive evaluation of rodent malaria parasite genomes and gene expression

scientific article

A conserved molecular motor drives cell invasion and gliding motility across malaria life cycle stages and other apicomplexan parasites

scientific article

A conserved parasite serine protease processes the Plasmodium falciparum merozoite surface protein-1.

scientific article published in November 1993

A divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of a malaria parasite during gametogony and transmission

scientific article published on 22 June 2020

A high molecular mass Plasmodium yoelii rhoptry protein binds to erythrocytes

scientific article published on 01 February 1996

A longitudinal study of naturally acquired cellular and humoral immune responses to a merozoite surface protein (MSP1) of Plasmodium falciparum in an area of seasonal malaria transmission.

scientific article

A member of the py235 gene family of Plasmodium yoelii encodes an erythrocyte binding protein recognised by a protective monoclonal antibody

scientific article

A novel Sushi domain-containing protein of Plasmodium falciparum

scientific article (publication date: March 2005)

A putative homologue of CDC20/CDH1 in the malaria parasite is essential for male gamete development

scientific article (publication date: February 2012)

A role for the protease falcipain 1 in host cell invasion by the human malaria parasite

scientific article (publication date: 6 December 2002)

A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.

scientific article

A strategy to sequence repetitive DNA based on partial restriction enzyme cleavage

scientific article published on 01 June 1995

A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion

scientific article

AcutePlasmodium chabaudi chabaudiMalaria Infection Induces Antibodies Which Bind to the Surfaces of Parasitized Erythrocytes and Promote Their Phagocytosis by Macrophages In Vitro

scientific article published on September 1, 1998

Adaptation of the genetically tractable malaria pathogen Plasmodium knowlesi to continuous culture in human erythrocytes

scientific article published on 24 December 2012

Alternative Protein Secretion in the Malaria Parasite Plasmodium falciparum

scientific article (publication date: 2015)

An S antigen gene from Plasmodium falciparum contains a novel repetitive sequence

scientific article published in February 1988

An ancient protein phosphatase, SHLP1, is critical to microneme development in Plasmodium ookinetes and parasite transmission

scientific article (publication date: 28 March 2013)

An engineered Plasmodium falciparum C-terminal 19-kilodalton merozoite surface protein 1 vaccine candidate induces high levels of interferon-gamma production associated with cellular immune responses to specific peptide sequences in Gambian adults n

scientific article published on December 2011

Analysis of nuclear and organellar genomes of Plasmodium knowlesi in humans reveals ancient population structure and recent recombination among host-specific subpopulations

scientific article published on 18 September 2017

Antibodies inhibit the protease-mediated processing of a malaria merozoite surface protein.

scientific article

Antibodies that Inhibit Malaria Merozoite Surface Protein–1 Processing and Erythrocyte Invasion Are Blocked by Naturally Acquired Human Antibodies

scientific article published on November 17, 1997

Antibody recognition of rodent malaria parasite antigens exposed at the infected erythrocyte surface: specificity of immunity generated in hyperimmune mice

scientific article

Antibody specificities of children living in a malaria endemic area to inhibitory and blocking epitopes on MSP-1 19 of Plasmodium falciparum.

scientific article published on 25 November 2008

Antigenic and sequence diversity at the C-terminus of the merozoite surface protein-1 from rodent malaria isolates, and the binding of protective monoclonal antibodies

scientific article published in November 1999

Antimalarial activity of cupredoxins: the interaction of Plasmodium merozoite surface protein 119 (MSP119) and rusticyanin

scientific article published on 07 June 2013

Apical expression of three RhopH1/Clag proteins as components of the Plasmodium falciparum RhopH complex

scientific article (publication date: September 2005)

Author Correction: Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis

scientific article published in Scientific Reports

Binding of Plasmodium falciparum Merozoite Surface Proteins DBLMSP and DBLMSP2 to Human Immunoglobulin M Is Conserved among Broadly Diverged Sequence Variants

scientific article (publication date: July 2016)

Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1

scientific article (publication date: October 2014)

Biosynthesis and processing of a Plasmodium falciparum schizont antigen recognized by immune serum and a monoclonal antibody.

scientific article

Calcium dependent protein kinase 1 and calcium fluxes in the malaria parasite

scientific article published on 24 April 2012

Cellular responses to modified Plasmodium falciparum MSP119 antigens in individuals previously exposed to natural malaria infection

scientific article

Characterisation of the cross-reacting carbohydrate groups on two variant surface glycoproteins of Trypanosoma brucei

scientific article published on 01 April 1983

Characterisation of the rhoph2 gene of Plasmodium falciparum and Plasmodium yoelii

scientific article

Characterization of N-myristoyltransferase from Plasmodium falciparum

scientific article published on June 2000

Characterization of human T- and B-cell epitopes in the C terminus of Plasmodium falciparum merozoite surface protein 1: evidence for poor T-cell recognition of polypeptides with numerous disulfide bonds

scientific article published on August 1, 1997

Characterization of the repertoire diversity of the Plasmodium falciparum stevor multigene family in laboratory and field isolates

scientific article published on 26 June 2009

Chromosomal organisation of a gene family encoding rhoptry proteins in Plasmodium yoelii

scientific article

Commit and Transmit: Molecular Players in Plasmodium Sexual Development and Zygote Differentiation

scientific article published on 10 September 2015

Comparative decline in funding of European Commission malaria vaccine projects: what next for the European scientists working in this field?

scientific article

Comparative testing of six antigen-based malaria vaccine candidates directed toward merozoite-stage Plasmodium falciparum

scientific article published on 11 June 2008

Comparison of two members of a multigene family coding for high-molecular mass rhoptry proteins of Plasmodium yoelii

scientific article published in February 1996

Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility

scientific article published on 11 September 2017

Construction and immunogenicity in mice of attenuated Salmonella typhi expressing Plasmodium falciparum merozoite surface protein 1 (MSP-1) fused to tetanus toxin fragment C.

scientific article published in September 2000

Construction of a Library for Sequencing Long Regions of Malarial Genomic DNA

scientific article published on July 1, 1997

Corrigendum to “Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analogues” [Bioorg. Med. Chem. Lett. 23 (2013) 6019–6024]

scholarly article by Jonathan M. Large published in January 2014

Current status of the Plasmodium falciparum genome project.

scientific article published on July 1996

Deletion of a malaria invasion gene reduces death and anemia, in model hosts

scientific article (publication date: 2011)

Deletion of the Plasmodium falciparum merozoite surface protein 7 gene impairs parasite invasion of erythrocytes

scientific article (publication date: December 2008)

Design and Synthesis of High Affinity Inhibitors of Plasmodium falciparum and Plasmodium vivax N -Myristoyltransferases Directed by Ligand Efficiency Dependent Lipophilicity (LELP)

scientific article

Design and Synthesis of Inhibitors of Plasmodium falciparumN -Myristoyltransferase, A Promising Target for Antimalarial Drug Discovery

scientific article

Developments with anti-malarial vaccines.

scientific article published on December 1993

Different Plasmodium falciparum recombinant MSP1(19) antigens differ in their capacities to stimulate in vitro peripheral blood T lymphocytes in individuals from various endemic areas

scientific article

Discovery of Novel and Ligand-Efficient Inhibitors of Plasmodium falciparum and Plasmodium vivax N -Myristoyltransferase

scientific article

Discovery of Plasmodium vivax N -Myristoyltransferase Inhibitors: Screening, Synthesis, and Structural Characterization of their Binding Mode

scientific article

Discovery of gene function by expression profiling of the malaria parasite life cycle

scientific article (publication date: 12 September 2003)

Discovery of pyridyl-based inhibitors of Plasmodium falciparum N-myristoyltransferase

scientific article published on 19 August 2015

Disruption of Plasmodium berghei merozoite surface protein 7 gene modulates parasite growth in vivo

scientific article published on 31 August 2004

Disulfide bonds in merozoite surface protein 1 of the malaria parasite impede efficient antigen processing and affect the in vivo antibody response

scientific article published in March 2004

Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites.

scientific article published on 11 June 2019

Diversity covering AMA1-MSP119 fusion proteins as malaria vaccines

scientific article published on 19 February 2013

Dual acylation of the 45 kDa gliding-associated protein (GAP45) in Plasmodium falciparum merozoites.

scientific article published on 19 May 2006

Effective induction of high-titer antibodies by viral vector vaccines

scientific article published on 27 July 2008

Epigenetic silencing of Plasmodium falciparum genes linked to erythrocyte invasion

scientific article

Epitopes in the 19kDa fragment of the Plasmodium falciparum major merozoite surface protein-1 (PfMSP-1(19)) recognized by human antibodies

scientific article published in May 1995

Expression of the 19-kilodalton carboxy-terminal fragment of the Plasmodium falciparum merozoite surface protein-1 in Escherichia coli as a correctly folded protein.

scientific article

Extensive differential protein phosphorylation as intraerythrocytic Plasmodium falciparum schizonts develop into extracellular invasive merozoites

scientific article published on 19 May 2015

Extensive proteolytic processing of the malaria parasite merozoite surface protein 7 during biosynthesis and parasite release from erythrocytes

scientific article published on 2 November 2006

Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites.

scientific article

Fine specificity of anti-MSP119 antibodies and multiplicity of Plasmodium falciparum merozoite surface protein 1 types in individuals in Nigeria with sub-microscopic infection

scientific article

Formation of the food vacuole in Plasmodium falciparum: a potential role for the 19 kDa fragment of merozoite surface protein 1 (MSP1(19))

scientific article

Formin' an invasion machine: actin polymerization in invading apicomplexans.

scientific article

Function of region I and II adhesive motifs of Plasmodium falciparum circumsporozoite protein in sporozoite motility and infectivity

scientific article (publication date: 6 December 2002)

Generating conditional gene knockouts in Plasmodium - a toolkit to produce stable DiCre recombinase-expressing parasite lines using CRISPR/Cas9.

scientific article published on 20 June 2017

Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation

scientific article (publication date: 9 July 2014)

Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle

scientific article

Glycopeptides from variant surface glycoproteins of Trypanosoma brucei. C-terminal location of antigenically cross-reacting carbohydrate moieties

scientific article published on 01 February 1981

Glycosyl-phosphatidylinositols in protozoa structure, biosynthesis and intracellular localisation

scientific article published on 01 February 1997

Glycosylphosphatidyl-inositols in murine malaria: Plasmodium yoelii yoelii

scientific article published in March 2003

Glycosylphosphatidylinositols of Plasmodium chabaudi chabaudi: a basis for the study of malarial glycolipid toxins in a rodent model

scientific article published on December 15, 1997

Human antibodies to the 19kDa C-terminal fragment of Plasmodium falciparum merozoite surface protein 1 inhibit parasite growth in vitro

scientific article

Human immune response to MSP-1

scientific article published on 01 May 1996

Human red blood cell-adapted Plasmodium knowlesi parasites: a new model system for malaria research

scientific article published on 12 March 2014

Hyperreactive malarial splenomegaly is associated with low levels of antibodies against red blood cell and Plasmodium falciparum derived glycolipids in Yanomami Amerindians from Venezuela

scientific article published on 27 December 2007

Identification and characterization of the Plasmodium yoelii PyP140/RON4 protein, an orthologue of Toxoplasma gondii RON4, whose cysteine-rich domain does not protect against lethal parasite challenge infection

scientific article

Identification of a stomatin orthologue in vacuoles induced in human erythrocytes by malaria parasites. A role for microbial raft proteins in apicomplexan vacuole biogenesis

scientific article published on 10 September 2003

Identification of new PNEPs indicates a substantial non-PEXEL exportome and underpins common features in Plasmodium falciparum protein export

scientific article (publication date: 2013)

Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development

scientific article published on 28 December 2015

Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analogues

scientific article published on 11 August 2013

Immunization against Plasmodium falciparum with recombinant polypeptides produced in Escherichia coli

scientific article published in November 1988

Immunization against blood-stage rodent malaria using purified parasite antigens

scientific article published in November 1981

Immunization against the murine malaria parasite Plasmodium yoelii using a recombinant protein with adjuvants developed for clinical use.

scientific article published in October 1997

Immunization with a recombinant C-terminal fragment of Plasmodium yoelii merozoite surface protein 1 protects mice against homologous but not heterologous P. yoelii sporozoite challenge

scientific article published on November 1, 1997

Immunoglobulin G antibodies to merozoite surface antigens are associated with recovery from chloroquine-resistant Plasmodium falciparum in Gambian children

scientific article

Inducible knockdown of Plasmodium gene expression using the glmS ribozyme

scientific article (publication date: 2013)

Inhibition of erythrocyte invasion and Plasmodium falciparum merozoite surface protein 1 processing by human immunoglobulin G1 (IgG1) and IgG3 antibodies.

scientific article published on 05 October 2009

Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion

scientific article published on 25 October 2021

Inhibitory and blocking monoclonal antibody epitopes on merozoite surface protein 1 of the malaria parasite Plasmodium falciparum

scientific article published in April 2001

Inhibitory and neutral antibodies to Plasmodium falciparum MSP119 form ring structures with their antigen

scientific article published in September 2004

Interaction and dynamics of the Plasmodium falciparum MTIP-MyoA complex, a key component of the invasion motor in the malaria parasite

scientific article

Isolation, expression and characterization of the gene for an ADP-ribosylation factor from the human malaria parasite, Plasmodium falciparum

scientific article (publication date: 15 November 1996)

Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission.

scientific article published in August 2019

Labeling and initial characterization of polar lipids in cultures of Plasmodium falciparum

article

Low plasma haptoglobin is a risk factor for life-threatening childhood severe malarial anemia and not an exclusive consequence of hemolysis

scientific article published in Scientific Reports

Lymphocyte response in vitro to Plasmodium falciparum merozoite antigens in donors from a holoendemic area

scientific article published in January 1993

Malaria induces anemia through CD8+ T cell-dependent parasite clearance and erythrocyte removal in the spleen

scientific article

Malaria parasite actin filaments are very short

scientific article published on 7 April 2005

Malaria parasite actin polymerization and filament structure

scientific article

Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surface protein-1(19) mapped by TROSY NMR.

scientific article published in November 2004

Malaria vaccines

article published in the Proceedings of the National Academy of Sciences of the United States of America

Malaria vaccines - how and when to proceed?

scientific article published on 17 October 2009

Malaria vaccines: where next?

scientific article

Melatonin signaling and its modulation of PfNF-YB transcription factor expression in Plasmodium falciparum.

scientific article published on July 2013

Merozoite surface protein 4/5 provides protection against lethal challenge with a heterologous malaria parasite strain.

scientific article published on October 2004

Merozoite surface proteins of the malaria parasite: The MSP1 complex and the MSP7 family

scientific article

Molecules incorporating a benzothiazole core scaffold inhibit the N-myristoyltransferase of Plasmodium falciparum.

scientific article published in December 2007

Monoclonal antibodies that inhibit Plasmodium falciparum invasion in vitro recognise the first growth factor-like domain of merozoite surface protein-1.

scientific article published in August 1993

Multiple genes code for high-molecular-mass rhoptry proteins of Plasmodium yoelii

scientific article published in March 1995

N-Myristoylation as a Drug Target in Malaria: Exploring the Role of N-Myristoyltransferase Substrates in the Inhibitor Mode of Action

scientific article published on 24 January 2018

N-myristoyltransferase: a prospective drug target for protozoan parasites

scientific article published on March 2008

N-terminal amino acid sequence of the Plasmodium falciparum merozoite surface protein-1 polypeptides

scientific article published on 01 July 1994

Naturally acquired cellular and humoral immune responses to the major merozoite surface antigen (PfMSP1) of Plasmodium falciparum are associated with reduced malaria morbidity.

scientific article

Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5.

scientific article

New Candidate Vaccines against Blood-Stage Plasmodium falciparum Malaria: Prime-Boost Immunization Regimens Incorporating Human and Simian Adenoviral Vectors and Poxviral Vectors Expressing an Optimized Antigen Based on Merozoite Surface Protein 1

scholarly article by Anna L. Goodman et al published 19 April 2011 in Infection and Immunity

New candidate vaccines against blood-stage Plasmodium falciparum malaria: prime-boost immunization regimens incorporating human and simian adenoviral vectors and poxviral vectors expressing an optimized antigen based on merozoite surface protein 1

scientific article

Normocyte-binding protein required for human erythrocyte invasion by the zoonotic malaria parasite Plasmodium knowlesi

scientific article published on 14 June 2016

Novel antimalarial antibodies highlight the importance of the antibody Fc region in mediating protection.

scientific article

Novel putative glycosylphosphatidylinositol-anchored micronemal antigen of Plasmodium falciparum that binds to erythrocytes

scientific article (publication date: December 2009)

Optimization of an imidazopyridazine series of inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1).

scientific article

PSLAP, a protein with multiple adhesive motifs, is expressed in Plasmodium falciparum gametocytes

scientific article (publication date: 30 April 2002)

Passive Immunization with Antibodies against Three Distinct Epitopes onPlasmodium yoeliiMerozoite Surface Protein 1 Suppresses Parasitemia

scientific article published on August 1, 1998

Passive immunization with a multicomponent vaccine against conserved domains of apical membrane antigen 1 and 235-kilodalton rhoptry proteins protects mice against Plasmodium yoelii blood-stage challenge infection.

scientific article

Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion

scientific article

Photosensitized INA-Labelled protein 1 (PhIL1) is novel component of the inner membrane complex and is required for Plasmodium parasite development.

scientific article published on 14 November 2017

Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis.

scientific article published on 4 April 2018

Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission.

scientific article published on 01 February 2020

Plasmodium DEH is ER-localized and crucial for oocyst mitotic division during malaria transmission

scientific article published on 26 October 2020

Plasmodium P-Type Cyclin CYC3 Modulates Endomitotic Growth during Oocyst Development in Mosquitoes

scientific article (publication date: November 2015)

Plasmodium Peekaboo: PK4 Mediates Parasite Latency

scientific article published in December 2017

Plasmodium chabaudi-infected erythrocytes adhere to CD36 and bind to microvascular endothelial cells in an organ-specific way

scientific article

Plasmodium falciparum 19-kilodalton merozoite surface protein 1 (MSP1)-specific antibodies that interfere with parasite growth in vitro can inhibit MSP1 processing, merozoite invasion, and intracellular parasite development

scientific article published on 27 December 2011

Plasmodium falciparum Rab5B is an N-terminally myristoylated Rab GTPase that is targeted to the parasite's plasma and food vacuole membranes

scientific article (publication date: 2014)

Plasmodium falciparum STEVOR proteins are highly expressed in patient isolates and located in the surface membranes of infected red blood cells and the apical tips of merozoites

scientific article published on 12 May 2008

Plasmodium falciparum aldolase and the C-terminal cytoplasmic domain of certain apical organellar proteins promote actin polymerization

scientific article (publication date: October 2014)

Plasmodium falciparum homologue of the genes for Plasmodium vivax and Plasmodium yoelii adhesive proteins, which is transcribed but not translated.

scientific article

Plasmodium falciparum infection of the placenta impacts on the T helper type 1 (Th1)/Th2 balance of neonatal T cells through CD4(+)CD25(+) forkhead box P3(+) regulatory T cells and interleukin-10.

scientific article published on 17 August 2009

Plasmodium falciparum: Merozoite Surface Proteins 1 and 2 Are Not Posttranslationally Modified by Classical N- or O-glycans

scientific article published on 01 March 2000

Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle

scientific article (publication date: April 2015)

Plasmodium kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission.

scientific article published in October 2019

Plasmodium thrombospondin related apical merozoite protein (PTRAMP) is shed from the surface of merozoites by PfSUB2 upon invasion of erythrocytes

scientific article (publication date: November 2006)

Plasmodium yoelii Erythrocyte-Binding-like Protein Modulates Host Cell Membrane Structure, Immunity, and Disease Severity

scientific article published on 07 January 2020

Plasmodium yoelii: Brefeldin A-Sensitive Processing of Proteins Targeted to the Rhoptries

scientific article published on 01 November 1994

Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites

scientific article

Precise epitope mapping of malaria parasite inhibitory antibodies by TROSY NMR cross-saturation

scientific article published in January 2005

Primary structure of the precursor to the three major surface antigens of Plasmodium falciparum merozoites

scientific article published in September 1985

Processing of the Plasmodium falciparum major merozoite surface protein-1: identification of a 33-kilodalton secondary processing product which is shed prior to erythrocyte invasion

scientific article published on 01 November 1991

Profiling the antibody immune response against blood stage malaria vaccine candidates

scientific article published on 17 May 2007

Protective antigens of rodent and human bloodstage malaria.

scientific article published on November 1984

Protective immune responses to the 42-kilodalton (kDa) region of Plasmodium yoelii merozoite surface protein 1 are induced by the C-terminal 19-kDa region but not by the adjacent 33-kDa region

scientific article

Protein phosphatase 1 regulates atypical mitotic and meiotic division in Plasmodium sexual stages

scientific article published on 18 June 2021

Proteolytic processing of the Plasmodium falciparum merozoite surface protein-1 produces a membrane-bound fragment containing two epidermal growth factor-like domains

scientific article published in November 1991

RON12, a novel Plasmodium-specific rhoptry neck protein important for parasite proliferation

scientific article

Real-time dynamics of Plasmodium NDC80 reveals unusual modes of chromosome segregation during parasite proliferation

scientific article published on 22 May 2020

Recombinant viral-vectored vaccines expressing Plasmodium chabaudi AS apical membrane antigen 1: mechanisms of vaccine-induced blood-stage protection

scientific article

Regulation of the Plasmodium Motor Complex: PHOSPHORYLATION OF MYOSIN A TAIL-INTERACTING PROTEIN (MTIP) LOOSENS ITS GRIP ON MyoA

scientific article

Secondary processing of the Plasmodium falciparum merozoite surface protein-1 (MSP1) by a calcium-dependent membrane-bound serine protease: shedding of MSP133 as a noncovalently associated complex with other fragments of the MSP1.

scientific article published in February 1992

Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs

scientific article

Sequence diversity and antigenic polymorphism in the Plasmodium yoelii p235 high molecular mass rhoptry proteins and their genes

scientific article published in February 2001

Serological cross-reaction between high molecular weight proteins synthesized in blood schizonts of Plasmodium yoelii, Plasmodium chabaudi and Plasmodium falciparum

scientific article

Sexual development in Plasmodium: lessons from functional analyses

scientific article

Site-specific N-terminal labelling of proteins in vitro and in vivo using N-myristoyl transferase and bioorthogonal ligation chemistry.

scientific article

Somatically Hypermutated Plasmodium-Specific IgM(+) Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge

scientific article published on 25 July 2016

Stage-specific transcription of distinct repertoires of a multigene family during Plasmodium life cycle.

scientific article

Structural analysis of the glycosyl-phosphatidylinositol membrane anchor of the merozoite surface proteins-1 and -2 of Plasmodium falciparum

scientific article (publication date: 1996)

Structural studies on Plasmodium vivax merozoite surface protein-1

scientific article

Structure of the E8 gene encoding a high molecular mass rhoptry protein of Plasmodium yoelii.

scientific article published in September 2000

Structure of the gene encoding a putative Schistosoma mansoni tegumental antigen precursor.

scientific article published on July 1993

Structure ofPlasmodium falciparumADP-ribosylation factor 1

scientific article

Structure-Guided Identification of Resistance Breaking Antimalarial N‑Myristoyltransferase Inhibitors

scientific article published on 09 May 2019

Subcellular location, phosphorylation and assembly into the motor complex of GAP45 during Plasmodium falciparum schizont development

scientific article (publication date: 2012)

Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1).

scientific article published on 21 March 2013

Suppressive and additive effects in protection mediated by combinations of monoclonal antibodies specific for merozoite surface protein 1 of Plasmodium yoelii.

scientific article

Suramin and suramin analogues inhibit merozoite surface protein-1 secondary processing and erythrocyte invasion by the malaria parasite Plasmodium falciparum

scientific article published on 17 September 2003

Surface antigens of malaria merozoites. A high molecular weight precursor is processed to an 83,000 mol wt form expressed on the surface of Plasmodium falciparum merozoites

scientific article published on November 1, 1983

Systematic analysis of Plasmodium myosins reveals differential expression, localisation, and function in invasive and proliferative parasite stages.

scientific article published in October 2019

Systematic genetic analysis of the Plasmodium falciparum MSP7-like family reveals differences in protein expression, location, and importance in asexual growth of the blood-stage parasite

scientific article (publication date: July 2010)

Targeted disruption of py235ebp-1: invasion of erythrocytes by Plasmodium yoelii using an alternative Py235 erythrocyte binding protein

scientific article

The 22 kDa component of the protein complex on the surface of Plasmodium falciparum merozoites is derived from a larger precursor, merozoite surface protein 7

scientific article

The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes

scientific article

The Binding of Plasmodium falciparum Adhesins and Erythrocyte Invasion Proteins to Aldolase Is Enhanced by Phosphorylation

scientific article

The Carbohydrate Structures of Trypanosoma brucei brucei MITat 1.6 Variant Surface Glycoprotein: A Reinvestigation of the C-Terminal Glycan

scientific article published on 01 November 1993

The MTIP-myosin A complex in blood stage malaria parasites

scientific article (publication date: 3 February 2006)

The Plasmodium Class XIV Myosin, MyoB, Has a Distinct Subcellular Location in Invasive and Motile Stages of the Malaria Parasite and an Unusual Light Chain

scientific article (publication date: 8 May 2015)

The Plasmodium falciparum clag9 gene encodes a rhoptry protein that is transferred to the host erythrocyte upon invasion

scientific article published on April 2004

The Plasmodium falciparum schizont phosphoproteome reveals extensive phosphatidylinositol and cAMP-protein kinase A signaling

scientific article published on 18 October 2012

The apicoplast genome of Leucocytozoon caulleryi, a pathogenic apicomplexan parasite of the chicken.

scientific article published on 04 December 2013

The carboxy-terminus of merozoite surface protein 1: structure, specific antibodies and immunity to malaria.

scientific article published on 23 July 2009

The combined epidermal growth factor-like modules of Plasmodium yoelii Merozoite Surface Protein-1 are required for a protective immune response to the parasite

scientific article published in August 1995

The fine specificity, but not the invasion inhibitory activity, of 19-kilodalton merozoite surface protein 1-specific antibodies is associated with resistance to malarial parasitemia in a cross-sectional survey in The Gambia

scientific article published on October 2004

The generation and evaluation of recombinant human IgA specific for Plasmodium falciparum merozoite surface protein 1-19 (PfMSP1 19).

scientific article

The high molecular mass rhoptry protein, RhopH1, is encoded by members of the clag multigene family in Plasmodium falciparum and Plasmodium yoelii

scientific article published in December 2001

The histones of Plasmodium falciparum: identification, purification and a possible role in the pathology of malaria

scientific article published in May 1997

The human immune response to Plasmodium falciparum includes both antibodies that inhibit merozoite surface protein 1 secondary processing and blocking antibodies

scientific article

The importance of human FcgammaRI in mediating protection to malaria

scientific article

The malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony

scientific article

The mechanism of erythrocyte invasion by the malarial parasite, Plasmodium falciparum

scientific article published on 05 October 2011

The merozoite surface protein 6 gene codes for a 36 kDa protein associated with the Plasmodium falciparum merozoite surface protein-1 complex

scientific article published in January 2001

The motor complex of Plasmodium falciparum: phosphorylation by a calcium-dependent protein kinase

scientific article published on 03 September 2008

The oligomerization domain of C4-binding protein (C4bp) acts as an adjuvant, and the fusion protein comprised of the 19-kilodalton merozoite surface protein 1 fused with the murine C4bp domain protects mice against malaria.

scientific article published on 12 May 2008

The role of calcium in the invasion of human erythrocytes by Plasmodium falciparum

scientific article published on 01 February 1992

The sequence of Plasmodium falciparum histone H3.

scientific article published in January 1995

The structure of Plasmodium yoelii merozoite surface protein 119, antibody specificity and implications for malaria vaccine design

scientific article

The three major antigens on the surface of Plasmodium falciparum merozoites are derived from a single high molecular weight precursor.

scientific article published on August 1984

The unique structure of the apicoplast genome of the rodent malaria parasite Plasmodium chabaudi chabaudi

scientific article

Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1

scientific article (publication date: 2011)

Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development

scientific article published on 22 June 2020

Use of a recombinant baculovirus product to measure naturally-acquired human antibodies to disulphide-constrained epitopes on the P. falciparum merozoite surface protein-1 (MSP1).

scientific article published in April 1993

Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach

scientific article

Variation in the expression of a Plasmodium falciparum protein family implicated in erythrocyte invasion

scientific article

Variation in the relationship between anti-MSP-1(19) antibody response and age in children infected with Plasmodium falciparum during the dry and rainy seasons

scientific article published in September 2005

What is the function of MSP-I on the malaria merozoite?

scientific article published in May 1994

centrin CEN-4 localizes to the putative MTOC and is dispensable for malaria parasite proliferation

article