List of works by Brian I. Carr

2-Methoxyestradiol inhibits hepatocellular carcinoma cell growth by inhibiting Cdc25 and inducing cell cycle arrest and apoptosis

scientific article

3-Deazaguanine: report of a phase I trial and drug-related cardiac toxicity

scientific article published in November 1990

90Y microsphere treatment of unresectable liver metastases: changes in 18F-FDG uptake and tumour size on PET/CT.

scientific article

A Cdc25A antagonizing K vitamin inhibits hepatocyte DNA synthesis in vitro and in vivo

scientific article

A Hepatocellular Carcinoma Aggressiveness Index and Its Relationship to Liver Enzyme Levels.

scientific article

A comparison of patients with hepatitis B- or hepatitis C-based advanced-stage hepatocellular carcinoma.

scientific article published on 28 January 2015

A liver colony assay for a new hepatocyte phenotype as a step toward purifying new cellular phenotypes that arise during hepatocarcinogenesis

scientific article published on 01 January 1980

A phase II study of raltitrexed ('Tomudex') in patients with hepatocellular carcinoma

scientific article published on 01 May 1997

A simple prognostic scoring system for patients with unresectable hepatocellular carcinoma treated by chemo-embolization

scientific article published on 09 April 2007

A systematic review of randomized controlled trials testing the efficacy of psychosocial interventions for gastrointestinal cancers.

scientific article published on June 2014

A systemic evolutionary approach to cancer: Hepatocarcinogenesis as a paradigm.

scientific article published on 24 May 2016

An assay for micrometastatic hepatocellular carcinoma

scientific article published on 01 January 1994

Angiotensin receptor blockers improve survival outcomes after radiofrequency ablation in hepatocarcinoma patients

scientific article published on 14 May 2015

Antagonism of sorafenib and regorafenib actions by platelet factors in hepatocellular carcinoma cell lines.

scientific article

Antiemetic effect of intravenous diazepam in patients receiving cis-diamminedichloroplatinum II: a pilot study.

scientific article published in January 1979

Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo.

scientific article published on July 2006

Antitumor and anticarcinogenic actions of Cpd 5: a new class of protein phosphatase inhibitor.

scientific article published on March 2003

Assessing spiritual growth and spiritual decline following a diagnosis of cancer: reliability and validity of the spiritual transformation scale.

scientific article published in February 2008

Association of abnormal plasma bilirubin with aggressive hepatocellular carcinoma phenotype

scientific article published on 6 March 2014

Binding of growth hormone to rat liver during experimental chemical hepatocarcinogenesis

scientific article published on 01 May 1986

Causes of death in patients with unresectable hepatocellular carcinoma.

scientific article published on 10 April 2007

Cdc25A and ERK interaction: EGFR-independent ERK activation by a protein phosphatase Cdc25A inhibitor, compound 5.

scientific article published on August 2005

Cell membrane and cytoplasmic epidermal growth factor receptor expression in pancreatic ductal adenocarcinoma

scientific article published on 25 January 2011

Chemo-embolization for unresectable hepatocellular carcinoma with different sizes of embolization particles

scientific article published on 29 November 2007

Chronic treatment with phenobarbital decreases the expression of rat liver EGF and insulin receptors

scientific article published on 01 March 1986

Clinical evaluation of lens culinaris agglutinin-reactive alpha-fetoprotein and des-gamma-carboxy prothrombin in histologically proven hepatocellular carcinoma in the United States

scientific article published on 01 March 2007

Clinical significance of elevated alpha-fetoprotein in adults and children.

scientific article published on August 2001

Clinically meaningful changes in health-related quality of life in patients diagnosed with hepatobiliary carcinoma

scientific article published on 15 December 2005

Co-expression and regulation of Met and Ron proto-oncogenes in human hepatocellular carcinoma tissues and cell lines

scientific article published on 01 July 1997

Comitogenic effects of vasoactive intestinal polypeptide on rat hepatocytes

scientific article published on 01 July 1996

Concomitant and isolated expression of TGF-alpha and EGF-R in human hepatoma cells supports the hypothesis of autocrine, paracrine, and endocrine growth of human hepatoma

scientific article published on 01 April 1995

Continuous five-day infusion of pala and 5FU: A pilot phase II trial ⬇️

scientific article published on January 1, 1983

Continuous infusion prochlorperazine: pharmacokinetics, antiemetic efficacy, and feasibility of high-dose therapy.

scientific article

Critical role of extracellular signal-regulated kinase (ERK) phosphorylation in novel vitamin K analog-induced cell death.

scientific article published in December 2000

DNA synthesis in rat hepatocytes: inhibition by a platelet factor and stimulation by an endogenous factor

scientific article published on 01 October 1985

Depression, immunity, and survival in patients with hepatobiliary carcinoma

scientific article published in June 2007

Detection of liver cells in peripheral blood of patients with advanced-stage hepatocellular carcinoma

scientific article published on 01 February 1995

Developments in liver transplantation for hepatocellular carcinoma

scientific article published on August 2012

Differential display and cloning of messenger RNAs from the late phase of rat liver regeneration

scientific journal article

Differential effects of two growth inhibitory K vitamin analogs on cell cycle regulating proteins in human hepatoma cells.

scientific article published in May 2003

Differential effects of vitamin K1 on AFP and DCP levels in patients with unresectable HCC and in HCC cell lines.

scientific article published on 28 December 2010

Differentially expressed genes in TGF-beta 1 sensitive and resistant human hepatoma cells.

scientific article published on February 1995

EGFR-independent activation of ERK1/2 mediates growth inhibition by a PTPase antagonizing K-vitamin analog

scientific article published in March 2002

ERCP and stent therapy for progressive jaundice in hepatocellular carcinoma: which patients benefit, which patients don't?

scientific article published on 01 July 1999

Economic evaluation of sorafenib in unresectable hepatocellular carcinoma ⬇️

scientific article published on November 1, 2010

Effects of low concentrations of regorafenib and sorafenib on human HCC cell AFP, migration, invasion, and growth in vitro.

scientific article published on June 2013

Effects of rapamycin on cultured hepatocyte proliferation and gene expression ⬇️

scientific article published on May 1, 1992

Effects of the hepatocarcinogen 2-acetylaminofluorene on insulin binding to microsomal and Golgi fractions of rat liver cells

scientific article published on 01 August 1984

Endothelin-1 expression by human hepatocellular carcinoma

scientific article published on 01 November 1995

Erratum to: Low Alpha-Fetoprotein Levels Are Associated with Improved Survival in Hepatocellular Carcinoma Patients with Portal Vein Thrombosis

scientific article published on 01 April 2016

Evaluation of responses to chemoembolization in patients with unresectable hepatocellular carcinoma.

scientific article published in February 2003

Evaluation of total hepatocellular cancer lifespan, including both clinically evident and preclinical development, using combined network phenotyping strategy and fisher information analysis

scientific article

Expression of the Hoxa-13 gene correlates to hepatitis B and C virus associated HCC.

scientific article

Features of massive hepatocellular carcinomas

scientific article published in January 2014

Fine needle aspiration diagnosis of hepatocellular carcinoma in metastatic sites

scientific article published on 01 May 1996

Fluorinated Cpd 5, a pure arylating K-vitamin derivative, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating MAPK.

scientific article published on 22 August 2006

Fluorinated NSC as a Cdc25 inhibitor.

scientific article published on 21 December 2006

Fluorinated quinoid inhibitor: possible "pure" arylator predicted by the simple theoretical calculation

scientific article published in August 2004

Gamma glutamyl transpeptidase as a prognostic biomarker in hepatocellular cancer patients especially with >5 cm tumors, treated by liver transplantation

scientific article published on 21 May 2020

Glutamic acid potentiates hepatocyte response to mitogens in primary culture

scientific article published on 01 February 1994

Growth control and gene expression in a new hepatocellular carcinoma cell line, Hep40: Inhibitory actions of vitamin K ⬇️

scientific article published on December 1, 1995

Growth inhibition and protein tyrosine phosphorylation in MCF 7 breast cancer cells by a novel K vitamin

scientific article published on 01 December 2000

Growth inhibition of hepatocellular carcinoma cells in vitro and in vivo by the 8-methoxy analog of WMC79.

scientific article

Growth inhibition of hepatoma cells induced by vitamin K and its analogs.

scientific article published on November 1995

Growth inhibitory actions of prothrombin on normal hepatocytes: influence of matrix.

scientific article

Guest editorial: Platelets and cancer

HCC and its microenvironment

scientific article

HCC in older patients.

scientific article published on 18 March 2010

Health-related quality of life: Hepatocellular carcinoma, chronic liver disease, and the general population

scientific article published on 21 November 2006

Hepatic artery chemoembolization for hepatocellular carcinoma recurrence confined to the transplanted liver.

scientific article published on 28 September 2012

Hepatic artery chemoembolization for the treatment of liver metastases from neuroendocrine tumors: a long-term follow-up in 123 patients

scientific article published on 24 November 2010

Hepatic parenchymal perfusion defects detected with CTAP: imaging-pathologic correlation

scientific article published on October 1, 1992

Hepatobiliary effects of 90yttrium microsphere therapy for unresectable hepatocellular carcinoma

scientific article published on 16 September 2008

Hepatocellular Carcinoma Extrahepatic Metastasis in Relation to Tumor Size and Alkaline Phosphatase Levels

scientific article

Hepatocellular carcinoma size: platelets, γ-glutamyl transpeptidase, and alkaline phosphatase

scientific article

Hepatocellular carcinoma: current management and future trends.

scientific article published in November 2004

Hepatocellular carcinoma: evaluation with biphasic, contrast-enhanced, helical CT.

scientific article

Hepatocyte growth factor enhances protein phosphatase Cdc25A inhibitor compound 5-induced hepatoma cell growth inhibition via Akt-mediated MAPK pathway.

scientific article published in June 2005

Hepatocyte proliferation and gene expression induced by triiodothyronine in vivo and in vitro

scientific article published on 01 November 1994

Herniated lumbar disc disease in patients with malignancy

scientific article published on 01 April 1987

IGF-1R tyrosine kinase inhibitors and Vitamin K1 enhance the antitumor effects of Regorafenib in HCC cell lines

scientific article published on 30 September 2017

Identification of a human hepatocellular carcinoma-associated tumor suppressor gene by differential display polymerase chain reaction.

scientific article published on January 1995

Identification of two clinical hepatocellular carcinoma patient phenotypes from results of standard screening parameters

scientific article

Induction of apoptosis via mitogen-activated protein kinase pathway by a K vitamin analog in rat hepatocytes.

scientific article published in January 2002

Integration of hepatitis B virus and alteration of the 1p36 region found in cancerous tissue of primary hepatocellular carcinoma with viral replication evidenced only in noncancerous, cirrhotic tissue ⬇️

scientific article published on November 1, 1995

Integrin alpha5-induced EGFR activation by prothrombin triggers hepatocyte apoptosis via the JNK signaling pathway

scientific article published in August 2008

Introduction: hepatocellular carcinoma

scientific article published on 01 August 2012

Involvement of ATM-mediated Chk1/2 and JNK kinase signaling activation in HKH40A-induced cell growth inhibition.

scientific article

Involvement of c-Myc in growth inhibition of Hep 3B human hepatoma cells by a vitamin K analog.

scientific article

Involvement of hepatocyte epidermal growth factor receptor mediated activation of mitogen-activated protein kinase signaling pathways in response to growth inhibition by a novel K vitamin

scientific article published on 01 June 2000

Involvement of receptor tyrosine phosphatase DEP-1 mediated PI3K-cofilin signaling pathway in sorafenib-induced cytoskeletal rearrangement in hepatoma cells.

scientific article published in August 2010

JS-K, a novel non-ionic diazeniumdiolate derivative, inhibits Hep 3B hepatoma cell growth and induces c-Jun phosphorylation via multiple MAP kinase pathways.

scientific article published in December 2003

K vitamins, PTP antagonism, and cell growth arrest.

scientific article

Liver Transplantation for Hepatocellular Carcinoma: Malatya Experience and Proposals for Expanded Criteria

scientific article published on 05 June 2020

Liver transplantation and chemotherapy for hepatoblastoma and hepatocellular cancer in childhood and adolescence

scientific article published on 01 June 2000

Liver transplantation for hepatocellular carcinoma

scientific article published on 01 January 1995

Low Alpha-Fetoprotein Levels Are Associated with Improved Survival in Hepatocellular Carcinoma Patients with Portal Vein Thrombosis.

scientific article published on 17 November 2015

Low alpha-fetoprotein HCC and the role of GGTP.

scientific article

Low alpha-fetoprotein hepatocellular carcinoma

scientific article published on 01 September 2010

MEK 1/2 inhibitors in the treatment of hepatocellular carcinoma.

scientific article published on 27 April 2015

Macro- and micro-environmental factors in clinical hepatocellular cancer

scientific article

Macroscopic Portal Vein Thrombosis in HCC Patients.

scientific article published on 13 June 2018

Measuring post-traumatic growth in people diagnosed with hepatobiliary cancer: directions for future research.

scientific article

Modulation of Regorafenib effects on HCC cell lines by epidermal growth factor

scientific article published on 24 April 2015

Modulation of sensitivity and resistance to multikinase inhibitors by microenvironmental platelet factors in HCC.

scientific article

Mutation at codon 249 of p53 gene in a human hepatoblastoma

scientific article published on 01 September 1993

Network-based analysis of survival for unresectable hepatocellular carcinoma.

scientific article published in April 2010

New Developments in Orthotopic Liver Transplant for Hepatocellular Carcinoma.

scientific article published in March 2017

Novel hydroxyl naphthoquinones with potent Cdc25 antagonizing and growth inhibitory properties.

scientific article

P53 but not p16INK4a induces growth arrest in retinoblastoma-deficient hepatocellular carcinoma cells.

scientific article published on August 2000

PM-20, a novel inhibitor of Cdc25A, induces extracellular signal-regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo

scientific article published on 01 June 2006

Pain at presentation and survival in hepatocellular carcinoma.

scientific article

Percutaneous biopsy of portal vein thrombus: a new staging technique for hepatocellular carcinoma

scientific article published on 01 August 1993

Percutaneous ultrasound-guided needle biopsy of hepatic mass lesions using a cytohistologic approach. Comparison of two needle types

scientific article published on 01 November 1995

Peripheral blood lymphocyte depletion after hepatic arterial 90Yttrium microsphere therapy for hepatocellular carcinoma

scientific article published on 23 May 2011

Persistent ERK phosphorylation negatively regulates cAMP response element-binding protein (CREB) activity via recruitment of CREB-binding protein to pp90RSK.

scientific article published on 22 January 2003

Phase I trial of menadiol diphosphate (vitamin K3) in advanced malignancy

scientific article published in June 2005

Phosphorylation regulates Myc expression via prolonged activation of the mitogen-activated protein kinase pathway.

scientific article published on July 2006

Platelet extracts induce growth, migration and invasion in human hepatocellular carcinoma in vitro

scientific article

Platelet-related phenotypic patterns in hepatocellular carcinoma patients

scientific article

Pleiotropic Effects of Heparins: From Clinical Applications to Molecular Mechanisms in Hepatocellular Carcinoma

scientific article published on 22 October 2018

Post-recurrence survival in hepatocellular carcinoma after percutaneous radiofrequency ablation.

scientific article

Posttraumatic growth, immunity and survival in patients with hepatoma

scientific article published on 07 April 2007

Preliminary results of an individually tailored psychosocial intervention for patients with advanced hepatobiliary carcinoma.

scientific article

Prognostic models in hepatocellular carcinoma (HCC) and statistical methodologies behind them.

scientific article published in January 2007

Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy

scientific article published in March 1990

Prospective randomized trial of hepatic artery chemotherapy with cisplatin and doxorubicin, with or without lipiodol in the treatment of advanced stage hepatocellular carcinoma

scientific article published on 01 October 2011

Proxy ratings of health related quality of life in patients with hepatocellular carcinoma

scientific article published on 01 May 2005

Quality of life in patients diagnosed with primary hepatocellular carcinoma: hepatic arterial infusion of Cisplatin versus 90-Yttrium microspheres (Therasphere).

scientific article published on February 2004

Quantitative assessment of the development of hepatoma in a buffalo rat model

scientific article published on 01 June 1997

Radiotherapy and multimodality management of cholangiocarcinoma

scientific article published on 01 April 1999

Refractory metastatic breast cancer: salvage therapy with fluorouracil and high-dose continuous infusion leucovorin calcium

scientific article published in April 1989

Regional hepatic therapy for cancer

scientific article published on 01 April 2010

Regional radioactive treatments for hepatocellular carcinoma

scientific article published on 01 August 2008

Renal carcinoma manifesting as breast mass

scientific article published on 01 February 1983

Resistance to multikinase inhibitor actions mediated by insulin like growth factor-1

scientific article

Resistance to the cytocidal effects of adriamycin is an early phenotypic change induced during hepatocarcinogenesis ⬇️

scientific article published on October 1, 1981

Reversibility of regorafenib effects in hepatocellular carcinoma cells.

scientific article published on October 2013

Role of Albumin in Growth Inhibition in Hepatocellular Carcinoma.

scientific article published on 10 May 2017

Safety and efficacy of 90Y radiotherapy for hepatocellular carcinoma with and without portal vein thrombosis

scientific article

Serum albumin levels in relation to tumor parameters in hepatocellular carcinoma patients.

scientific article published on 28 August 2017

Serum ferritin as a new prognostic factor in hepatocellular carcinoma patients treated with radiofrequency ablation

scientific article published on 01 November 2014

Serum levels of inflammatory markers CRP, ESR and albumin in relation to survival for patients with hepatocellular carcinoma

scientific article published on 24 June 2020

Sexual functioning in patients with hepatocellular carcinoma.

scientific article published in November 2005

Significance of platelet and AFP levels and liver function parameters for HCC size and survival.

scientific article published in July 2014

Small HCCs identified by screening

scientific article published on 05 April 2011

Small hepatocellular carcinoma in Chinese patients.

scientific article published in July 2011

Small hepatocellular carcinomas and thrombocytopenia

scientific article

Sorafenib combined vitamin K induces apoptosis in human pancreatic cancer cell lines through RAF/MEK/ERK and c-Jun NH2-terminal kinase pathways.

scientific article published on July 2010

Stimulation of hepatocyte DNA synthesis by neurotensin

scientific article published in February 1994

Systematic prediction of human membrane receptor interactions

scientific article

The ALBI grade provides objective hepatic reserve estimation across each BCLC stage of hepatocellular carcinoma.

scientific article published on 24 September 2016

The antiandrogen cyproterone acetate induces synthesis of transforming growth factor beta 1 in the parenchymal cells of the liver accompanied by an enhanced sensitivity to undergo apoptosis and necrosis without inflammation

scientific article published on 01 February 1996

The effects of hepatic artery chemotherapy on viral hepatitis in patients with hepatocellular carcinoma.

scientific article

The growth inhibitory effects of vitamins K and their actions on gene expression ⬇️

scientific article published on September 1, 1995

The inhibitory effect of interleukin 1beta on rat hepatocyte DNA synthesis is mediated by nitric oxide

scientific article

The prediction of risk of recurrence and time to recurrence of hepatocellular carcinoma after orthotopic liver transplantation: a pilot study

scientific article published in August 1997

The role of psychosocial factors in the progression of hepatocellular carcinoma.

scientific article published in January 2004

The use of granulocyte-macrophage colony-stimulating factor to enhance hematologic parameters of patients with cirrhosis and hypersplenism.

scientific article

Thrombocytopenia in relation to tumor size in patients with hepatocellular carcinoma

scientific article

Thrombocytosis and hepatocellular carcinoma

scientific article

To transplant, or not to transplant?

scientific article published in May 2003

Transforming growth factor alpha (TGFalpha) in hepatocellular carcinomas and adjacent hepatic parenchyma

scientific article published on 01 March 1998

Treatment before liver transplantation for HCC.

scientific article published on 31 January 2008

Treatment of unresectable cholangiocarcinoma with gemcitabine-based transcatheter arterial chemoembolization (TACE): a single-institution experience.

scientific article

Treatment of unresectable hepatocellular carcinoma with intrahepatic yttrium 90 microspheres: a risk-stratification analysis.

scientific article

Treatment of unresectable hepatocellular carcinoma with intrahepatic yttrium 90 microspheres: factors associated with liver toxicities.

scientific article published in February 2005

Use of intrahepatic chemotherapy to treat advanced pediatric hepatic malignancies

scientific article published on 01 February 2000

Validation of a Liver Index and Its Significance for HCC Aggressiveness

scientific article published on 01 September 2017

Validation of the Concept of a Common Typical Time of Disease Duration for Hepatocellular Carcinoma Patients Using the Fisher Information Processing of Tumor Imaging Results Combined With Network Phenotyping Strategy Quantification of Individual Pat

scientific article

Viruses and cancer: introduction

scientific article published on 31 December 2014

Vitamin K uptake in hepatocytes and hepatoma cells

scientific article

Welcome to the journal of Gastrointestinal Cancer, 2010

scientific article published on 01 March 2010

Yttrium-90 microspheres for the treatment of hepatocellular carcinoma.

scientific article published in November 2004

alpha-Thrombin inhibits DNA synthesis in rat hepatocytes but not in hepatoma cells by receptor activation and proteolysis

scientific article published on 22 May 2007

c-Met-Akt pathway-mediated enhancement of inhibitory c-Raf phosphorylation is involved in vitamin K1 and sorafenib synergy on HCC growth inhibition.

scientific article published on 15 September 2011

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