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List of works by Anneliese O Speak

A high-throughput in vivo screening method in the mouse for identifying regulators of metastatic colonization

scientific article published on 2 November 2017

A screen for combination therapies in BRAF/NRAS wild type melanoma identifies nilotinib plus MEK inhibitor as a synergistic combination

A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma

scientific article

Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole-body energy expenditure

scientific article published on 29 April 2016

Altered distribution and function of natural killer cells in murine and human Niemann-Pick disease type C1.

scientific article

Beneficial effects of substrate reduction therapy in a mouse model of GM1 gangliosidosis

scientific article published in April 2008

CD1d presentation of glycolipids

scientific article published on 10 June 2008

CD8α⁺β⁻ and CD8α⁺β⁺ plasmacytoid dendritic cells induce Foxp3⁺ regulatory T cells and prevent the induction of airway hyper-reactivity.

scientific article

CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation

scientific article published on 23 March 2021

Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery.

scientific article published on 16 March 2014

Corrigendum to "Disruption of the potassium channel regulatory subunit KCNE2 causes iron-deficient anemia" [Experimental Hematology, Vol. 42, Issue 12, p1053-1058.e1].

scientific article published on April 2015

Disruption of the potassium channel regulatory subunit KCNE2 causes iron-deficient anemia

scientific article published on 12 August 2014

Diverse endogenous antigens for mouse NKT cells: self-antigens that are not glycosphingolipids

scientific article

FBXO7 sensitivity of phenotypic traits elucidated by a hypomorphic allele

scientific article published on 06 March 2019

Genome wide in vivo mouse screen data from studies to assess host regulation of metastatic colonisation

scientific article published on 12 September 2017

Genome-wide in vivo screen identifies novel host regulators of metastatic colonization

scientific article published on 4 January 2017

Glycosphingolipid depletion in PC12 cells using iminosugars protects neuronal membranes from anti-ganglioside antibody mediated injury

scientific article published in October 2008

Glycosphingolipids Gb3 and iGb3. In vivo roles in hemolytic-uremic syndrome and iNKT cell function

scientific article

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation

scientific article published on 16 December 2019

Immune dysfunction in Niemann-Pick disease type C.

scientific article published on 6 May 2015

Impact of temporal variation on design and analysis of mouse knockout phenotyping studies

scientific article

Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals

scholarly article

Infection Susceptibility in Gastric Intrinsic Factor (Vitamin B12)-Defective Mice Is Subject to Maternal Influences

scientific article published on 21 June 2016

Interleukin-22 promotes phagolysosomal fusion to induce protection against Typhimurium in human epithelial cells

article published in the Proceedings of the National Academy of Sciences of the United States of America

Invariant NKT cells in adrenoleukodystrophy patients and mice

scientific article published on 01 December 2010

Invariant natural killer T cells are not affected by lysosomal storage in patients with Niemann-Pick disease type C.

scientific article

Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection

scientific article

Modulation of human natural killer T cell ligands on TLR-mediated antigen-presenting cell activation

scholarly article

Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency

scholarly article

Prevalence of sexual dimorphism in mammalian phenotypic traits

scientific article

Programmed cell death ligand 2 regulates TH9 differentiation and induction of chronic airway hyperreactivity

scientific article published on 20 November 2012

Relative acidic compartment volume as a lysosomal storage disorder-associated biomarker

scientific article published on March 2014

Synthetic lethality between PAXX and XLF in mammalian development

scientific article published on October 2016

T cell fate and clonality inference from single-cell transcriptomes

scientific article

The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis

scientific article

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