List of works - Parvesh Wadhwani

19F NMR Analysis of the Antimicrobial Peptide PGLa Bound to Native Cell Membranes from Bacterial Protoplasts and Human Erythrocytes

article

19F NMR screening of unrelated antimicrobial peptides shows that membrane interactions are largely governed by lipids

article published in 2014

19F-Labeling of Peptides Revealing Long-Range NMR Distances in Fluid Membranes

2H-NMR and MD Simulations Reveal Membrane-Bound Conformation of Magainin 2 and Its Synergy with PGLa

scientific article published in November 2016

4-fluorophenylglycine as a label for 19F NMR structure analysis of membrane-associated peptides

scientific article published in November 2003

A critical evaluation of the conformational requirements of fusogenic peptides in membranes

A fluorescence polarization assay for the experimental validation of an in silico model of the chemokine CXCL8 binding to receptor-derived peptides

scientific article

A novel dendrimeric peptide with antimicrobial properties: structure-function analysis of SB056.

scientific article

Action of the multifunctional peptide BP100 on native biomembranes examined by solid-state NMR

Alanine scan and (2)H NMR analysis of the membrane-active peptide BP100 point to a distinct carpet mechanism of action

scientific article

An antifungal protein from Ginkgo biloba binds actin and can trigger cell death

scientific article published on 28 August 2015

Antibiotic gold: tethering of antimicrobial peptides to gold nanoparticles maintains conformational flexibility of peptides and improves trypsin susceptibility

scientific article

Antimicrobial Peptides can Enhance the Risk of Persistent Infections

scientific article published on August 2012

Antimicrobial and cell-penetrating peptides induce lipid vesicle fusion by folding and aggregation

scientific article

CD44v6-Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells.

scientific article published on 20 December 2016

Cell surface clustering of heparan sulfate proteoglycans by amphipathic cell-penetrating peptides does not contribute to uptake

scientific article

Challenge Integrity: The Cell-Penetrating Peptide BP100 Interferes with the Auxin-Actin Oscillator

scientific article

Chemical labeling strategy with (R)- and (S)-trifluoromethylalanine for solid state 19F NMR analysis of peptaibols in membranes

scientific article published in November 2009

Comparative analysis of the orientation of transmembrane peptides using solid-state (2)H- and (15)N-NMR: mobility matters

scientific article published on 28 March 2012

Concentration-dependent realignment of the antimicrobial peptide PGLa in lipid membranes observed by solid-state 19F-NMR.

scientific article published on 4 February 2005

Conditions affecting the re-alignment of the antimicrobial peptide PGLa in membranes as monitored by solid state 2H-NMR.

scientific article

Conformation and membrane orientation of amphiphilic helical peptides by oriented circular dichroism

scientific article published on 11 July 2008

Dynamical structure of the short multifunctional peptide BP100 in membranes

scientific article

Enhanced amphiphilic profile of a short β-stranded peptide improves its antimicrobial activity

scientific article published on 24 January 2015

Extending the Hydrophobic Mismatch Concept to Amphiphilic Membranolytic Peptides

Fluorinated amino acids in amyloid formation: a symphony of size, hydrophobicity and α-helix propensity

article published in 2014

Helix Fraying and Lipid-Dependent Structure of a Short Amphipathic Membrane-Bound Peptide Revealed by Solid-State NMR

scientific article published on 01 June 2018

Homo- and heteromeric interaction strengths of the synergistic antimicrobial peptides PGLa and magainin 2 in membranes

Hydrophobic mismatch demonstrated for membranolytic peptides, and their use as molecular rulers to measure bilayer thickness in native cells

scientific article published on 25 March 2015

Influence of C-terminal amidation on the antimicrobial and hemolytic activities of cationic α-helical peptides

Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa

scientific article published on 22 April 2015

Influence of the Length and Charge on the Activity of α-Helical Amphipathic Antimicrobial Peptides

scientific article

Irregular structure of the HIV fusion peptide in membranes demonstrated by solid-state NMR and MD simulations

scientific article published on 28 January 2011

Lactam-Stapled Cell-Penetrating Peptides: Cell Uptake and Membrane Binding Properties

scientific article published on 18 September 2017

Lipid shape is a key factor for membrane interactions of amphipathic helical peptides

article by Erik Strandberg et al published July 2012 in BBA - Biomembranes

Membrane-active peptides and the clustering of anionic lipids.

scientific article published on 17 July 2012

Molecular mechanism of synergy between the antimicrobial peptides PGLa and magainin 2.

scientific article published on 13 October 2017

Optimized Protocol for Synthesis of Cyclic Gramicidin S: Starting Amino Acid Is Key to High Yield

Orientation of the antimicrobial peptide PGLa in lipid membranes determined from 19F-NMR dipolar couplings of 4-CF3-phenylglycine labels

scientific article published in May 2004

Oriented Circular Dichroism: A Method to Characterize Membrane-Active Peptides in Oriented Lipid Bilayers

scientific article

Peptide-lipid interactions of the stress-response peptide TisB that induces bacterial persistence

scientific article

Preferential uptake of L- versus D-amino acid cell-penetrating peptides in a cell type-dependent manner

scientific article

Rational design of a peptide capture agent for CXCL8 based on a model of the CXCL8:CXCR1 complex

scholarly article in RSC Advances, vol. 5 no. 33, 2015

Rational modification of a dendrimeric peptide with antimicrobial activity: consequences on membrane-binding and biological properties.

scientific article published on 27 November 2015

Self-Assembly of Flexible β-Strands into Immobile Amyloid-Like β-Sheets in Membranes As Revealed by Solid-State 19F NMR

scientific article published in 2012

Solid State NMR Structure Analysis of the Antimicrobial Peptide Gramicidin S in Lipid Membranes: Concentration-Dependent Re-alignment and Self-Assembly as a β-Barrel

article

Solid state NMR analysis of the dipolar couplings within and between distant CF3-groups in a membrane-bound peptide.

scientific article published on 21 August 2006

Solid-State NMR Analysis Comparing the Designer-Made Antibiotic MSI-103 with Its Parent Peptide PGLa in Lipid Bilayers†

article

Solid-state NMR analysis of the PGLa peptide orientation in DMPC bilayers: structural fidelity of 2H-labels versus high sensitivity of 19F-NMR.

scientific article published on 9 December 2005

Stereochemical effects on the aggregation and biological properties of the fibril-forming peptide [KIGAKI]3 in membranes

scientific article published on 7 May 2013

Structural and functional characterization of the pore-forming domain of pinholin S2168

scientific article published on 05 November 2020

Structure analysis and conformational transitions of the cell penetrating peptide transportan 10 in the membrane-bound state

scientific article

Structure analysis of the membrane-bound dermcidin-derived peptide SSL-25 from human sweat

scientific article published on 6 September 2017

Synergistic Transmembrane Alignment of the Antimicrobial Heterodimer PGLa/Magainin

scientific article published in Journal of Biological Chemistry

Synergistic insertion of antimicrobial magainin-family peptides in membranes depends on the lipid spontaneous curvature

scientific article published on 19 March 2013

Synergistic interaction between silver nanoparticles and membrane-permeabilizing antimicrobial peptides

scientific article published on 15 June 2009

Synergistic transmembrane insertion of the heterodimeric PGLa/magainin 2 complex studied by solid-state NMR.

scientific article published on 14 January 2009

Temperature-dependent transmembrane insertion of the amphiphilic peptide PGLa in lipid bilayers observed by solid state 19F NMR spectroscopy

scientific article published in December 2008

Tetrameric Charge-Zipper Assembly of the TisB Peptide in Membranes-Computer Simulation and Experiment

scientific article published on 14 February 2019

The cell-penetrating peptide TAT(48-60) induces a non-lamellar phase in DMPC membranes

UV-CD12: synchrotron radiation circular dichroism beamline at ANKA.

scientific article

Using a Sterically Restrictive Amino Acid as a19F NMR label To Monitor and To Control Peptide Aggregation in Membranes

scientific article published on 01 December 2008

Using the peptide BP100 as a cell-penetrating tool for the chemical engineering of actin filaments within living plant cells

scientific article published on January 2011

List of works by Parvesh Wadhwani

19F NMR Analysis of the Antimicrobial Peptide PGLa Bound to Native Cell Membranes from Bacterial Protoplasts and Human Erythrocytes

19F NMR screening of unrelated antimicrobial peptides shows that membrane interactions are largely governed by lipids

19F-Labeling of Peptides Revealing Long-Range NMR Distances in Fluid Membranes

2H-NMR and MD Simulations Reveal Membrane-Bound Conformation of Magainin 2 and Its Synergy with PGLa

4-fluorophenylglycine as a label for 19F NMR structure analysis of membrane-associated peptides

A critical evaluation of the conformational requirements of fusogenic peptides in membranes

A fluorescence polarization assay for the experimental validation of an in silico model of the chemokine CXCL8 binding to receptor-derived peptides

A novel dendrimeric peptide with antimicrobial properties: structure-function analysis of SB056.

Action of the multifunctional peptide BP100 on native biomembranes examined by solid-state NMR

Alanine scan and (2)H NMR analysis of the membrane-active peptide BP100 point to a distinct carpet mechanism of action

An antifungal protein from Ginkgo biloba binds actin and can trigger cell death

Antibiotic gold: tethering of antimicrobial peptides to gold nanoparticles maintains conformational flexibility of peptides and improves trypsin susceptibility

Antimicrobial Peptides can Enhance the Risk of Persistent Infections

Antimicrobial and cell-penetrating peptides induce lipid vesicle fusion by folding and aggregation

CD44v6-Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells.

Cell surface clustering of heparan sulfate proteoglycans by amphipathic cell-penetrating peptides does not contribute to uptake

Challenge Integrity: The Cell-Penetrating Peptide BP100 Interferes with the Auxin-Actin Oscillator

Chemical labeling strategy with (R)- and (S)-trifluoromethylalanine for solid state 19F NMR analysis of peptaibols in membranes

Comparative analysis of the orientation of transmembrane peptides using solid-state (2)H- and (15)N-NMR: mobility matters

Concentration-dependent realignment of the antimicrobial peptide PGLa in lipid membranes observed by solid-state 19F-NMR.

Conditions affecting the re-alignment of the antimicrobial peptide PGLa in membranes as monitored by solid state 2H-NMR.

Conformation and membrane orientation of amphiphilic helical peptides by oriented circular dichroism

Dynamical structure of the short multifunctional peptide BP100 in membranes

Enhanced amphiphilic profile of a short β-stranded peptide improves its antimicrobial activity

Extending the Hydrophobic Mismatch Concept to Amphiphilic Membranolytic Peptides

Fluorinated amino acids in amyloid formation: a symphony of size, hydrophobicity and α-helix propensity

Helix Fraying and Lipid-Dependent Structure of a Short Amphipathic Membrane-Bound Peptide Revealed by Solid-State NMR

Homo- and heteromeric interaction strengths of the synergistic antimicrobial peptides PGLa and magainin 2 in membranes

Hydrophobic mismatch demonstrated for membranolytic peptides, and their use as molecular rulers to measure bilayer thickness in native cells

Influence of C-terminal amidation on the antimicrobial and hemolytic activities of cationic α-helical peptides

Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa

Influence of the Length and Charge on the Activity of α-Helical Amphipathic Antimicrobial Peptides

Irregular structure of the HIV fusion peptide in membranes demonstrated by solid-state NMR and MD simulations

Lactam-Stapled Cell-Penetrating Peptides: Cell Uptake and Membrane Binding Properties

Lipid shape is a key factor for membrane interactions of amphipathic helical peptides

Membrane-active peptides and the clustering of anionic lipids.

Molecular mechanism of synergy between the antimicrobial peptides PGLa and magainin 2.

Optimized Protocol for Synthesis of Cyclic Gramicidin S: Starting Amino Acid Is Key to High Yield

Orientation of the antimicrobial peptide PGLa in lipid membranes determined from 19F-NMR dipolar couplings of 4-CF3-phenylglycine labels

Oriented Circular Dichroism: A Method to Characterize Membrane-Active Peptides in Oriented Lipid Bilayers

Peptide-lipid interactions of the stress-response peptide TisB that induces bacterial persistence

Preferential uptake of L- versus D-amino acid cell-penetrating peptides in a cell type-dependent manner

Rational design of a peptide capture agent for CXCL8 based on a model of the CXCL8:CXCR1 complex

Rational modification of a dendrimeric peptide with antimicrobial activity: consequences on membrane-binding and biological properties.

Self-Assembly of Flexible β-Strands into Immobile Amyloid-Like β-Sheets in Membranes As Revealed by Solid-State 19F NMR

Solid State NMR Structure Analysis of the Antimicrobial Peptide Gramicidin S in Lipid Membranes: Concentration-Dependent Re-alignment and Self-Assembly as a β-Barrel

Solid state NMR analysis of the dipolar couplings within and between distant CF3-groups in a membrane-bound peptide.

Solid-State NMR Analysis Comparing the Designer-Made Antibiotic MSI-103 with Its Parent Peptide PGLa in Lipid Bilayers†

Solid-state NMR analysis of the PGLa peptide orientation in DMPC bilayers: structural fidelity of 2H-labels versus high sensitivity of 19F-NMR.

Stereochemical effects on the aggregation and biological properties of the fibril-forming peptide [KIGAKI]3 in membranes

Structural and functional characterization of the pore-forming domain of pinholin S2168

Structure analysis and conformational transitions of the cell penetrating peptide transportan 10 in the membrane-bound state

Structure analysis of the membrane-bound dermcidin-derived peptide SSL-25 from human sweat

Synergistic Transmembrane Alignment of the Antimicrobial Heterodimer PGLa/Magainin

Synergistic insertion of antimicrobial magainin-family peptides in membranes depends on the lipid spontaneous curvature

Synergistic interaction between silver nanoparticles and membrane-permeabilizing antimicrobial peptides

Synergistic transmembrane insertion of the heterodimeric PGLa/magainin 2 complex studied by solid-state NMR.

Temperature-dependent transmembrane insertion of the amphiphilic peptide PGLa in lipid bilayers observed by solid state 19F NMR spectroscopy

Tetrameric Charge-Zipper Assembly of the TisB Peptide in Membranes-Computer Simulation and Experiment

The cell-penetrating peptide TAT(48-60) induces a non-lamellar phase in DMPC membranes

UV-CD12: synchrotron radiation circular dichroism beamline at ANKA.

Using a Sterically Restrictive Amino Acid as a19F NMR label To Monitor and To Control Peptide Aggregation in Membranes

Using the peptide BP100 as a cell-penetrating tool for the chemical engineering of actin filaments within living plant cells