List of works by Antonio Simeone

5′-Cleavage site of D. melanogaster 18 S rRNA

scientific article published on 01 February 1984

A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1(+/-) mice

scientific journal article

A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo

scientific journal article

A human homoeo box gene specifically expressed in spinal cord during embryonic development

scientific article

A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nuclei

scientific article

Altered dopaminergic innervation and amphetamine response in adult Otx2 conditional mutant mice

scientific article published on 26 October 2005

An agarose gel resolving a wide range of DNA fragment lengths.

scientific article published in October 1983

Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon

scientific article published in October 2008

Bmp5/7 in concert with the mid-hindbrain organizer control development of noradrenergic locus coeruleus neurons

scientific article published on 21 May 2010

Cellular heterogeneity during embryonic stem cell differentiation to epiblast stem cells is revealed by the ShcD/RaLP adaptor protein

scientific article

Chromosome locations of human EMX and OTX genes

scientific article (publication date: July 1994)

Cloning of the human interferon-related developmental regulator (IFRD1) gene coding for the PC4 protein, a member of a novel family of developmentally regulated genes

scientific article

Comparative analysis of Otx2, Gbx2, Pax2, Fgf8 and Wnt1 gene expressions during the formation of the chick midbrain/hindbrain domain.

scientific article

Conserved usage of gap and homeotic genes in patterning the CNS.

scientific article

Developmental rescue of Drosophila cephalic defects by the human Otx genes

scientific article

Dickkopf 3 Promotes the Differentiation of a Rostrolateral Midbrain Dopaminergic Neuronal Subset In Vivo and from Pluripotent Stem Cells In Vitro in the Mouse.

scientific article published in September 2015

Differential and stage-related expression in embryonic tissues of a new human homoeobox gene

scientific article

Differential patterns of expression of Eps15 and Eps15R during mouse embryogenesis.

scientific article published in July 2000

Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells ⬇️

scientific article published on March 1, 1991

Differentiation of cerebellar cell identities in absence of Fgf signalling in zebrafish Otx morphants

scientific article published on 12 April 2006

EVX2, a human homeobox gene homologous to the even-skipped segmentation gene, is localized at the 5' end of HOX4 locus on chromosome 2

scientific article (publication date: May 1991)

Embryonic defects and growth alteration in mice with homozygous disruption of the Patz1 gene

scientific article published in March 2013

Embryonic expression pattern of the murine figf gene, a growth factor belonging to platelet-derived growth factor/vascular endothelial growth factor family

scientific article published in May 1998

Epilepsy and brain abnormalities in mice lacking the Otx1 gene

scientific article

Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non-Hodgkin Lymphoma

scientific article

FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum

scientific article

Fgf15-mediated control of neurogenic and proneural gene expression regulates dorsal midbrain neurogenesis

scientific article

Foxg1 is required for proper separation and formation of sensory cristae during inner ear development.

scientific article published in November 2009

Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells

scientific article

Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors

scientific article

Genetic Otx2 mis-localization delays critical period plasticity across brain regions

scientific article published on 14 February 2017

Genetic and molecular roles of Otx homeodomain proteins in head development.

scientific article

Genetic control of dopaminergic neuron differentiation

scientific article

Germline mutations in the homeobox gene EMX2 in patients with severe schizencephaly.

scientific article

Graded Otx2 activities demonstrate dose-sensitive eye and retina phenotypes

scientific article published on 13 November 2013

Hepatocyte growth factor induces proliferation and differentiation of multipotent and erythroid hemopoietic progenitors.

scientific article

Human HOX genes are differentially activated by retinoic acid in embryonal carcinoma cells according to their position within the four loci

article

Human NRD convertase: a highly conserved metalloendopeptidase expressed at specific sites during development and in adult tissues

scientific article

Immunoprecipitation and mass spectrometry identify non-cell autonomous Otx2 homeoprotein in the granular and supragranular layers of mouse visual cortex

scientific article published on 30 July 2014

Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: effects on locomotor behavior and seizure susceptibility

scientific article published on 30 December 2013

Inheritance of the rDNA spacer in D. melanogaster

Isolation and expression of the homeobox gene Gbx1 during mouse development

scientific article

Isolation and mapping of EVx1, a human homeobox gene homologus toeven-skipped, localized at the 5′ end of Hox1 locus on chromosome 7 ⬇️

scientific article published on December 11, 1991

Loss of glutamatergic pyramidal neurons in frontal and temporal cortex resulting from attenuation of FGFR1 signaling is associated with spontaneous hyperactivity in mice

scientific journal article

Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast

scientific article published on 8 June 2016

Mitochondrial Protection by Exogenous Otx2 in Mouse Retinal Neurons

scientific article published on 22 October 2015

Modulated expression of human homeobox genes in differentiating intestinal cells.

scientific article published in July 1987

Molecular analysis of the heterogeneity region of the human ribosomal spacer.

scientific article

Morphogenesis and evolution

scientific article published in 1986

Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain

scientific journal article

OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm

scientific article published in August 2003

Orthopedia Homeodomain Protein Is Essential for Diencephalic Dopaminergic Neuron Development

scholarly article by Soojin Ryu et al published February 2008 in Current Biology

Orthopedia homeodomain protein is essential for diencephalic dopaminergic neuron development

scientific journal article

Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and Drosophila

scientific article published on July 1994

Otx genes and the genetic control of brain morphogenesis.

scientific article

Otx genes in brain morphogenesis

scientific article

Otx genes in corticogenesis and brain development

scientific article

Otx genes in evolution: are they involved in instructing the vertebrate brain morphology?

article

Otx genes in neurogenesis of mesencephalic dopaminergic neurons

scientific article published on August 2011

Otx genes in the development and evolution of the vertebrate brain.

scientific article published in July 2001

Otx genes in the evolution of the vertebrate brain

scientific article

Otx1 null mutant mice show partial segregation of sensory epithelia comparable to lamprey ears.

scientific article published in September 2001

Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity

scientific article published on 11 December 2013

Otx2 controls identity and fate of glutamatergic progenitors of the thalamus by repressing GABAergic differentiation.

scientific article

Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP.

scientific article published on 7 November 2010

Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain

scientific article published in January 2010

Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition

scientific article published on 15 November 2012

Otx2 regulates subtype specification and neurogenesis in the midbrain

scientific journal article

Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain

scientific article

Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability

scientific article published on 29 October 2012

Patterning of the mammalian cochlea

scientific article

Positioning the isthmic organizer where Otx2 and Gbx2meet.

scientific article

Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene

scientific journal article

Reorganization of enhancer patterns in transition from naive to primed pluripotency

scientific article published on June 2014

Retinoic acid induces stage-specific antero-posterior transformation of rostral central nervous system.

scientific article published in May 1995

Retinoic acid induces stage-specific repatterning of the rostral central nervous system.

scientific article published in May 1996

Role of Otx transcription factors in brain development

article

Selective inactivation of Otx2 mRNA isoforms reveals isoform-specific requirement for visceral endoderm anteriorization and head morphogenesis and highlights cell diversity in the visceral endoderm

scientific article

Sequence organization of the ribosomal spacer of D.melanogaster.

scientific article

Serotonin hyperinnervation abolishes seizure susceptibility in Otx2 conditional mutant mice

scientific article

Sox6 and Otx2 control the specification of substantia nigra and ventral tegmental area dopamine neurons

scientific article published on 7 August 2014

Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border

scientific article published on 29 March 2006

TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation

scientific article

The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival.

scientific article

The Otx family

scientific article

The TINS Lecture. Understanding the roles of Otx1 and Otx2 in the control of brain morphogenesis

scientific article published in March 1999

The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord

scientific article

The paired-type homeobox gene Dmbx1 marks the midbrain and pretectum

scientific article

The role of Otx genes in progenitor domains of ventral midbrain

scientific article published on January 2009

The role of otx2 in adult mesencephalic-diencephalic dopaminergic neurons

scientific article

The transcription factor Otx2 regulates choroid plexus development and function

scientific article

The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons.

scientific article

Three new class I HLA alleles: structure of mRNAs and alternative mechanisms of processing

scientific article

Towards the comprehension of genetic mechanisms controlling brain morphogenesis

scientific article

Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development

scientific article

Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development

scientific article

Unsuspected role of the brain morphogenetic gene Otx1 in hematopoiesis

scientific article

Xrx1, a novel Xenopus homeobox gene expressed during eye and pineal gland development.

scientific article published in January 1997

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