List of works - Antoni Riera

2-Piperidino-1,1,2-triphenylethanol: a highly effective catalyst for the enantioselective arylation of aldehydes.

scientific article published in April 2004

A tetradecapeptide somatostatin dicarba-analog: Synthesis, structural impact and biological activity.

scientific article published on 3 December 2013

Addition of HOBt improves the conversion of thioester-Amine chemical ligation.

scientific article published on 22 September 2015

Addition of diethylzinc to dicobalt hexacarbonyl complexes of alpha,beta-acetylenic aldehydes with virtually complete enantioselectivity. A formal synthesis of (+)-incrustoporin

scientific article published on 01 July 2002

Amino acids with fluorescent tetrazine ethers as bioorthogonal handles for peptide modification

scientific article published in 2022

Asymmetric Approach to (+)-beta-Cuparenone by Intramolecular Pauson-Khand Reaction

scientific article published on 01 December 1996

Asymmetric Pauson-Khand reactions using camphor-derived chelating thiols as chiral controllers.

scientific article

Asymmetric allylation/Pauson-Khand reaction: a simple entry to polycyclic amines. Application to the synthesis of aminosteroid analogues

scientific article published on 07 February 2014

Asymmetric approach to Pauson-Khand bicyclization. Enantioselective formal synthesis of hirsutene

scientific article published in 1990

Asymmetric intermolecular Pauson-Khand reaction of symmetrically substituted alkynes

scientific article published on 01 October 2009

Asymmetric intermolecular cobalt-catalyzed Pauson-Khand reaction using a P-stereogenic bis-phosphane

scientific article published on 29 December 2014

Borane as an efficient directing group. Stereoselective 1,2-addition of organometallic reagents to borane P-stereogenic N-phosphanylimines

scientific article published on 01 February 2015

Boron trifluoride-induced, new stereospecific rearrangements of chiral epoxy ethers. Ready access to enantiopure 4-(diarylmethyl)-1,3-dioxolanes and 4,5-disubstituted tetrahydrobenzo[c]oxepin-4-ols

scientific article published in February 2006

Catalytic Regioselective Isomerization of 2,2-Disubstituted Oxetanes to Homoallylic Alcohols

scientific article published on 25 January 2020

Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation

scientific article published on November 2012

Dialkylammonium tert-Butylmethylphosphinites: Stable Intermediates for the Synthesis of P-Stereogenic Ligands.

scientific article published on 22 June 2017

Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst

scientific article published on 29 November 2018

EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor

scientific article published on 29 June 2016

Efficient Synthesis of Polycyclic γ-Lactams by Catalytic Carbonylation of Ene-Imines via Nickelacycle Intermediates

scientific article published on 12 June 2017

Efficient stereoselective synthesis of 2-acetamido-1,2-dideoxyallonojirimycin (DAJNAc) and sp(2)-iminosugar conjugates: Novel hexosaminidase inhibitors with discrimination capabilities between the mature and precursor forms of the enzyme

scientific article published on 26 October 2015

Enantioselective syntheses of carbanucleosides from the Pauson-Khand adduct of trimethylsilylacetylene and norbornadiene

scientific article published on 18 September 2008

Enantioselective synthesis of indolizidine alkaloid trans-209D.

scientific article

Enantioselective synthesis of sphingadienines and aromatic ceramide analogs

scientific article published on 02 September 2011

Enantioselective synthesis of trans-4-methylpipecolic acid

scientific article published on 06 September 2007

Extending the Substrate Scope in the Hydrogenation of Unfunctionalized Tetrasubstituted Olefins with Ir-P Stereogenic Aminophosphine-Oxazoline Catalysts

scientific article published on 16 January 2019

Fine-tuning the π-π aromatic interactions in peptides: somatostatin analogues containing mesityl alanine.

scientific article published on 9 December 2011

General approach to glycosidase inhibitors. Enantioselective synthesis of deoxymannojirimycin and swainsonine

scientific article

Half-sandwich complexes of Ir(iii), Rh(iii) and Ru(ii) with the MaxPhos ligand: metal centred chirality and cyclometallation

scientific article published on 8 November 2017

Highly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Aryl Allyl Phthalimides

scientific article published on 08 November 2019

Highly Enantioselective Iridium-Catalyzed Hydrogenation of Cyclic Enamides.

scientific article published on 17 May 2016

Insights into structure-activity relationships of somatostatin analogs containing mesitylalanine.

scientific article published on 25 November 2013

Intermolecular Pauson-Khand reactions of cyclopropene: a general synthesis of cyclopentanones

scientific article published on 01 October 2001

Iridium-Catalyzed Isomerization of N-Sulfonyl Aziridines to Allyl Amines

scientific article published on 06 September 2018

Low-energy pathway for pauson-khand reactions: synthesis and reactivity of dicobalt hexacarbonyl complexes of chiral ynamines

scientific article published on 01 November 2000

Modular amino alcohol ligands containing bulky alkyl groups as chiral controllers for Et2Zn addition to aldehydes: illustration of a design principle.

scientific article

Molecular basis of the selective binding of MDMA enantiomers to the alpha4beta2 nicotinic receptor subtype: synthesis, pharmacological evaluation and mechanistic studies

scientific article published on 02 May 2014

N-phosphino sulfinamide ligands: an efficient manner to combine sulfur chirality and phosphorus coordination behavior

scientific article published on 01 January 2007

N-phosphino-p-tolylsulfinamide ligands: synthesis, stability, and application to the intermolecular Pauson-Khand reaction.

scientific article published on 26 August 2008

New camphor-derived sulfur chiral controllers: Synthesis of (2R-exo)-10-methylthio-2-bornanethiol and (2R-exo)-2,10-bis(methylthio)bornane

New stereodivergent approach to 3-amino-2,3,6-trideoxysugars. Enantioselective synthesis of daunosamine, ristosamine, acosamine, and epi-daunosamine

scientific article

P-Stereogenic Amino-Phosphines as Chiral Ligands: From Privileged Intermediates to Asymmetric Catalysis

scientific article published on 27 February 2020

P-Stereogenic and Non-P-Stereogenic Ir-MaxPHOX in the Asymmetric Hydrogenation of N-Aryl Imines. Isolation and X-ray Analysis of Imine Iridacycles.

scientific article published on 4 April 2018

P-Stereogenic bisphosphines with a hydrazine backbone: from N-N atropoisomerism to double nitrogen inversion.

scientific article published in April 2017

P-stereogenic secondary iminophosphorane ligands and their rhodium(I) complexes: taking advantage of NH/PH tautomerism

scientific article published on 13 June 2012

Pauson-Khand adducts of N-Boc-propargylamine: a new approach to 4,5-disubstituted cyclopentenones

scientific article published on 28 May 2013

Pauson-Khand reaction of internal dissymmetric trifluoromethyl alkynes. Influence of the alkene on the regioselectivity.

scientific article

Peptide aromatic interactions modulated by fluorinated residues: Synthesis, structure and biological activity of Somatostatin analogs containing 3-(3',5'difluorophenyl)-alanine

scientific article

Phosphine-alkene ligands as mechanistic probes in the Pauson-Khand reaction

scientific article published in July 2010

Phosphine-dependent stereoselectivity in the mitsunobu cyclodehydration of 1,2-diols: stereodivergent approach to triaryl-substituted epoxides

scientific article published on 25 January 2007

Phosphine-substrate recognition through the C-H...O hydrogen bond: application to the asymmetric Pauson-Khand reaction

scientific article published in October 2005

Photochemical rearrangements of norbornadiene Pauson-Khand cycloadducts

scientific article published on 01 January 2007

Photochemistry of 3-substituted bicyclo[3.1.0]hex-3-en-2-ones. Regioselective synthesis of ortho-substituted phenols by Pauson-Khand reaction

scientific article published on 01 October 2001

Polystyrene-supported (R)-2-piperazino-1,1,2-triphenylethanol: a readily available supported ligand with unparalleled catalytic activity and enantioselectivity.

scientific article published in January 2005

Primary and secondary aminophosphines as novel P-stereogenic building blocks for ligand synthesis

scientific article published on 01 December 2010

PuPHOS: a synthetically useful chiral bidentate ligand for the intermolecular Pauson-Khand reaction.

scientific article published in November 2004

Regioselectivity in intermolecular Pauson-Khand reactions of dissymmetric fluorinated alkynes.

scientific article published on 17 November 2010

Regioselectivity of intermolecular Pauson-Khand reaction of aliphatic alkynes: experimental and theoretical study of the effect of alkyne polarization

scientific article published on 05 November 2014

Ring-closing metathesis of chiral allylamines. Enantioselective synthesis of (2S,3R,4S)-3,4-dihydroxyproline.

scientific article published in October 2002

SSTR1- and SSTR3-Selective Somatostatin Analogues

scientific article published on 21 January 2011

Solvent and substituent effects on the photochemistry of norbornadiene-diarylacetylene Pauson-Khand adducts

scientific article published on 04 March 2011

Stereodivergent SN2@P Reactions of Borane Oxazaphospholidines: Experimental and Theoretical Studies

scientific article published on 7 March 2013

Stereodivergent syntheses of conduramines and aminocyclitols.

scientific article

Stereoselective Synthesis of 2-Acetamido-1,2-dideoxyallonojirimycin (DAJNAc), a New Potent Hexosaminidase Inhibitor

scientific article published on 26 June 2013

Stereoselective synthesis of 2-acetamido-1,2-dideoxynojirimycin (DNJNAc) and ureido-DNJNAc derivatives as new hexosaminidase inhibitors

scientific article published on 15 May 2015

Stereoselective synthesis of P-stereogenic aminophosphines: ring opening of bulky oxazaphospholidines

scientific article published on 29 March 2011

Stereospecific S(N)2@P reactions: novel access to bulky P-stereogenic ligands.

scientific article published in December 2015

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

scientific article published on 23 February 2015

Structure of the N-terminal domain of the protein Expansion: an 'Expansion' to the Smad MH2 fold.

scientific article

Synthesis and Application of 3-Bromo-1,2,4,5-Tetrazine for Protein Labeling to Trigger Click-to-Release Biorthogonal Reactions

scientific article published on 26 February 2020

Synthesis and NMR experiments of (4,5,6-13C)-deoxymannojirimycin. A new entry to 13C-labeled glycosidase inhibitors

scientific article published on 29 April 2007

Synthesis and application of β-substituted Pauson-Khand adducts: trifluoromethyl as a removable steering group.

scientific article

Synthesis and coordination chemistry of enantiopure t-BuMeP(O)H.

scientific article published on 28 March 2018

Synthesis of 3-alkyl-6-methyl-1,2,4,5-tetrazines via a Sonogashira-type cross-coupling reaction

scientific article published on 19 August 2020

Synthesis of heavily substituted 1,2-amino alcohols in enantiomerically pure form

scientific article published in September 2005

Synthesis of prostaglandin and phytoprostane B1 via regioselective intermolecular Pauson-Khand reactions

scientific article published on 01 July 2009

Synthetic applications of chiral unsaturated epoxy alcohols prepared by sharpless asymmetric epoxidation.

scientific article published on 23 February 2010

TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

scientific article published on 14 February 2018

Tetramethylnorbornadiene, a versatile alkene for cyclopentenone synthesis through intermolecular Pauson-Khand reactions

scientific article published on 26 June 2012

The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.

scientific article published on January 2017

The Pauson-Khand reaction of medium sized trans-cycloalkenes

scientific article published in April 2013

The conjugate addition-Peterson olefination reaction for the preparation of cross-conjugated cyclopentenone, PPAR-gamma ligands.

scientific article

Thermal and photochemical rearrangement of bicyclo[3.1.0]hex-3-en-2-one to the ketonic tautomer of phenol. Computational evidence for the formation of a diradical rather than a zwitterionic intermediate.

scientific article

Total Synthesis of ( R)-Sarkomycin Methyl Ester via Regioselective Intermolecular Pauson-Khand Reaction and Iridium-Catalyzed Asymmetric Isomerization

scientific article published on 15 June 2018

List of works by Antoni Riera

2-Piperidino-1,1,2-triphenylethanol: a highly effective catalyst for the enantioselective arylation of aldehydes.

A tetradecapeptide somatostatin dicarba-analog: Synthesis, structural impact and biological activity.

Addition of HOBt improves the conversion of thioester-Amine chemical ligation.

Addition of diethylzinc to dicobalt hexacarbonyl complexes of alpha,beta-acetylenic aldehydes with virtually complete enantioselectivity. A formal synthesis of (+)-incrustoporin

Amino acids with fluorescent tetrazine ethers as bioorthogonal handles for peptide modification

Asymmetric Approach to (+)-beta-Cuparenone by Intramolecular Pauson-Khand Reaction

Asymmetric Pauson-Khand reactions using camphor-derived chelating thiols as chiral controllers.

Asymmetric allylation/Pauson-Khand reaction: a simple entry to polycyclic amines. Application to the synthesis of aminosteroid analogues

Asymmetric approach to Pauson-Khand bicyclization. Enantioselective formal synthesis of hirsutene

Asymmetric intermolecular Pauson-Khand reaction of symmetrically substituted alkynes

Asymmetric intermolecular cobalt-catalyzed Pauson-Khand reaction using a P-stereogenic bis-phosphane

Borane as an efficient directing group. Stereoselective 1,2-addition of organometallic reagents to borane P-stereogenic N-phosphanylimines

Boron trifluoride-induced, new stereospecific rearrangements of chiral epoxy ethers. Ready access to enantiopure 4-(diarylmethyl)-1,3-dioxolanes and 4,5-disubstituted tetrahydrobenzo[c]oxepin-4-ols

Catalytic Regioselective Isomerization of 2,2-Disubstituted Oxetanes to Homoallylic Alcohols

Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation

Dialkylammonium tert-Butylmethylphosphinites: Stable Intermediates for the Synthesis of P-Stereogenic Ligands.

Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst

EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor

Efficient Synthesis of Polycyclic γ-Lactams by Catalytic Carbonylation of Ene-Imines via Nickelacycle Intermediates

Efficient stereoselective synthesis of 2-acetamido-1,2-dideoxyallonojirimycin (DAJNAc) and sp(2)-iminosugar conjugates: Novel hexosaminidase inhibitors with discrimination capabilities between the mature and precursor forms of the enzyme

Enantioselective syntheses of carbanucleosides from the Pauson-Khand adduct of trimethylsilylacetylene and norbornadiene

Enantioselective synthesis of indolizidine alkaloid trans-209D.

Enantioselective synthesis of sphingadienines and aromatic ceramide analogs

Enantioselective synthesis of trans-4-methylpipecolic acid

Extending the Substrate Scope in the Hydrogenation of Unfunctionalized Tetrasubstituted Olefins with Ir-P Stereogenic Aminophosphine-Oxazoline Catalysts

Fine-tuning the π-π aromatic interactions in peptides: somatostatin analogues containing mesityl alanine.

General approach to glycosidase inhibitors. Enantioselective synthesis of deoxymannojirimycin and swainsonine

Half-sandwich complexes of Ir(iii), Rh(iii) and Ru(ii) with the MaxPhos ligand: metal centred chirality and cyclometallation

Highly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Aryl Allyl Phthalimides

Highly Enantioselective Iridium-Catalyzed Hydrogenation of Cyclic Enamides.

Insights into structure-activity relationships of somatostatin analogs containing mesitylalanine.

Intermolecular Pauson-Khand reactions of cyclopropene: a general synthesis of cyclopentanones

Iridium-Catalyzed Isomerization of N-Sulfonyl Aziridines to Allyl Amines

Low-energy pathway for pauson-khand reactions: synthesis and reactivity of dicobalt hexacarbonyl complexes of chiral ynamines

Modular amino alcohol ligands containing bulky alkyl groups as chiral controllers for Et2Zn addition to aldehydes: illustration of a design principle.

Molecular basis of the selective binding of MDMA enantiomers to the alpha4beta2 nicotinic receptor subtype: synthesis, pharmacological evaluation and mechanistic studies

N-phosphino sulfinamide ligands: an efficient manner to combine sulfur chirality and phosphorus coordination behavior

N-phosphino-p-tolylsulfinamide ligands: synthesis, stability, and application to the intermolecular Pauson-Khand reaction.

New camphor-derived sulfur chiral controllers: Synthesis of (2R-exo)-10-methylthio-2-bornanethiol and (2R-exo)-2,10-bis(methylthio)bornane

New stereodivergent approach to 3-amino-2,3,6-trideoxysugars. Enantioselective synthesis of daunosamine, ristosamine, acosamine, and epi-daunosamine

P-Stereogenic Amino-Phosphines as Chiral Ligands: From Privileged Intermediates to Asymmetric Catalysis

P-Stereogenic and Non-P-Stereogenic Ir-MaxPHOX in the Asymmetric Hydrogenation of N-Aryl Imines. Isolation and X-ray Analysis of Imine Iridacycles.

P-Stereogenic bisphosphines with a hydrazine backbone: from N-N atropoisomerism to double nitrogen inversion.

P-stereogenic secondary iminophosphorane ligands and their rhodium(I) complexes: taking advantage of NH/PH tautomerism

Pauson-Khand adducts of N-Boc-propargylamine: a new approach to 4,5-disubstituted cyclopentenones

Pauson-Khand reaction of internal dissymmetric trifluoromethyl alkynes. Influence of the alkene on the regioselectivity.

Peptide aromatic interactions modulated by fluorinated residues: Synthesis, structure and biological activity of Somatostatin analogs containing 3-(3',5'difluorophenyl)-alanine

Phosphine-alkene ligands as mechanistic probes in the Pauson-Khand reaction

Phosphine-dependent stereoselectivity in the mitsunobu cyclodehydration of 1,2-diols: stereodivergent approach to triaryl-substituted epoxides

Phosphine-substrate recognition through the C-H...O hydrogen bond: application to the asymmetric Pauson-Khand reaction

Photochemical rearrangements of norbornadiene Pauson-Khand cycloadducts

Photochemistry of 3-substituted bicyclo[3.1.0]hex-3-en-2-ones. Regioselective synthesis of ortho-substituted phenols by Pauson-Khand reaction

Polystyrene-supported (R)-2-piperazino-1,1,2-triphenylethanol: a readily available supported ligand with unparalleled catalytic activity and enantioselectivity.

Primary and secondary aminophosphines as novel P-stereogenic building blocks for ligand synthesis

PuPHOS: a synthetically useful chiral bidentate ligand for the intermolecular Pauson-Khand reaction.

Regioselectivity in intermolecular Pauson-Khand reactions of dissymmetric fluorinated alkynes.

Regioselectivity of intermolecular Pauson-Khand reaction of aliphatic alkynes: experimental and theoretical study of the effect of alkyne polarization

Ring-closing metathesis of chiral allylamines. Enantioselective synthesis of (2S,3R,4S)-3,4-dihydroxyproline.

SSTR1- and SSTR3-Selective Somatostatin Analogues

Solvent and substituent effects on the photochemistry of norbornadiene-diarylacetylene Pauson-Khand adducts

Stereodivergent SN2@P Reactions of Borane Oxazaphospholidines: Experimental and Theoretical Studies

Stereodivergent syntheses of conduramines and aminocyclitols.

Stereoselective Synthesis of 2-Acetamido-1,2-dideoxyallonojirimycin (DAJNAc), a New Potent Hexosaminidase Inhibitor

Stereoselective synthesis of 2-acetamido-1,2-dideoxynojirimycin (DNJNAc) and ureido-DNJNAc derivatives as new hexosaminidase inhibitors

Stereoselective synthesis of P-stereogenic aminophosphines: ring opening of bulky oxazaphospholidines

Stereospecific S(N)2@P reactions: novel access to bulky P-stereogenic ligands.

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

Structure of the N-terminal domain of the protein Expansion: an 'Expansion' to the Smad MH2 fold.

Synthesis and Application of 3-Bromo-1,2,4,5-Tetrazine for Protein Labeling to Trigger Click-to-Release Biorthogonal Reactions

Synthesis and NMR experiments of (4,5,6-13C)-deoxymannojirimycin. A new entry to 13C-labeled glycosidase inhibitors

Synthesis and application of β-substituted Pauson-Khand adducts: trifluoromethyl as a removable steering group.

Synthesis and coordination chemistry of enantiopure t-BuMeP(O)H.

Synthesis of 3-alkyl-6-methyl-1,2,4,5-tetrazines via a Sonogashira-type cross-coupling reaction

Synthesis of heavily substituted 1,2-amino alcohols in enantiomerically pure form

Synthesis of prostaglandin and phytoprostane B1 via regioselective intermolecular Pauson-Khand reactions

Synthetic applications of chiral unsaturated epoxy alcohols prepared by sharpless asymmetric epoxidation.

TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

Tetramethylnorbornadiene, a versatile alkene for cyclopentenone synthesis through intermolecular Pauson-Khand reactions

The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.