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List of works by Karen M Polizzi

A GenoChemetic strategy for derivatization of the violacein natural product scaffold

A Modular Method for Directing Protein Self-Assembly

scientific article published on 09 April 2020

A label-free optical whole-cell Escherichia coli biosensor for the detection of pyrethroid insecticide exposure

scientific article published on 28 August 2019

A low-cost biological agglutination assay for medical diagnostic applications

A streamlined cloning workflow minimising the time-to-strain pipeline for Pichia pastoris

scientific article published on 17 November 2017

A systematic analysis of the expression of the anti-HIV VRC01 antibody in Pichia pastoris through signal peptide optimization

scientific article published on 27 March 2018

An experimental approach probing the conformational transitions and energy landscape of antibodies: a glimmer of hope for reviving lost therapeutic candidates using ionic liquid

scientific article published on 22 June 2021

An improved model for the analysis of combined antimicrobials: a replacement for the Chou-Talalay combination index method.

scientific article published on 27 October 2017

BeQuIK (Biosensor Engineered Quorum Induced Killing): designer bacteria for destroying recalcitrant biofilms

scientific article published on 21 July 2019

Binding of human BiP to the ER stress transducers IRE1 and PERK requires ATP ⬇️

scientific article published on March 13, 2012

Biosensor-assisted engineering of a high-yield Pichia pastoris cell-free protein synthesis platform

scientific article published on 11 January 2019

Computational Re-design of Synthetic Genetic Oscillators for Independent Amplitude and Frequency Modulation

scientific article published on 18 April 2018

Constructing vesicle-based artificial cells with embedded living cells as organelle-like modules.

scientific article published on 14 March 2018

Correction to EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology

scientific article published on 17 April 2020

EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology

scientific article published on 01 January 2018

EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology

scientific article

Exploring cellular behavior under transient gene expression and its impact on mAb productivity and Fc-glycosylation

scientific article

Functionalizing cell-mimetic giant vesicles with encapsulated bacterial biosensors

scientific article published on 17 August 2018

Improving the reaction mix of a Pichia pastoris cell-free system using a design of experiments approach to minimise experimental effort

scientific article published on 23 June 2020

In Situ Monitoring of Intracellular Glucose and Glutamine in CHO Cell Culture ⬇️

scientific article published on April 3, 2012

Knockout of RSN1, TVP18 or CSC1-2 causes perturbation of Golgi cisternae in Pichia pastoris

scientific article published on 02 December 2020

Liquid PTVA: a faster and cheaper alternative for generating multi-copy clones in Pichia pastoris

scientific article

Low-cost and user-friendly biosensor to test the integrity of mRNA molecules suitable for field applications

scientific article published on 07 May 2019

Metabolic network reconstruction: advances in in silico interpretation of analytical information ⬇️

scientific article published on November 24, 2011

Microbial interventions are an easier alternative to engineer higher organisms

scientific article published on 18 October 2020

Model-based investigation of intracellular processes determining antibody Fc-glycosylation under mild hypothermia.

scientific article published on 21 November 2016

Model-based optimization of antibody galactosylation in CHO cell culture

scientific article published on 21 March 2019

Rapid acquisition and model-based analysis of cell-free transcription-translation reactions from nonmodel bacteria.

scientific article published on 17 April 2018

Sense and sensitivity in bioprocessing-detecting cellular metabolites with biosensors.

scientific article published on 10 June 2017

Streptomyces venezuelae TX-TL - a next generation cell-free synthetic biology tool.

scientific article published on 31 January 2017

Tools for engineering coordinated system behaviour in synthetic microbial consortia

scientific article published in Nature Communications

Whole-Cell Biosensor with Tunable Limit of Detection Enables Low-Cost Agglutination Assays for Medical Diagnostic Applications

scientific article published on 25 January 2019

Whole-cell Escherichia coli lactate biosensor for monitoring mammalian cell cultures during biopharmaceutical production.

scientific article published on 23 January 2017

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