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List of works by Kate Vandyke

A niche-dependent myeloid transcriptome signature defines dormant myeloma cells

scientific article published on 25 April 2019

Androgen decreases osteoprotegerin expression in prostate cancer cells.

scientific article published on 26 December 2006

Circulating N-cadherin levels are a negative prognostic indicator in patients with multiple myeloma.

scientific article

Clodronate-Liposome Mediated Macrophage Depletion Abrogates Multiple Myeloma Tumor Establishment In Vivo

scientific article published on 24 June 2019

DNA Barcoding Reveals Habitual Clonal Dominance of Myeloma Plasma Cells in the Bone Marrow Microenvironment.

scientific article published on 26 October 2017

Dysregulation of bone remodeling by imatinib mesylate.

scientific article

EZH2 deletion in early mesenchyme compromises postnatal bone microarchitecture and structural integrity and accelerates remodeling.

scientific article published in December 2016

Engineering interaction between bone marrow derived endothelial cells and electrospun surfaces for artificial vascular graft applications.

scientific article

EphB4 enhances the process of endochondral ossification and inhibits remodeling during bone fracture repair

article

GLIPR1 expression is reduced in multiple myeloma but is not a tumour suppressor in mice

scientific article published on 29 January 2020

HIF-2α Promotes Dissemination of Plasma Cells in Multiple Myeloma by Regulating CXCL12/CXCR4 and CCR1.

scientific article published on 30 August 2017

Identification of Novel EZH2 Targets Regulating Osteogenic Differentiation in Mesenchymal Stem Cells

scientific article published on 10 May 2016

Immunomodulatory Properties of Induced Pluripotent Stem Cell-Derived Mesenchymal Cells.

scientific article published on 11 May 2016

N-cadherin in cancer metastasis, its emerging role in haematological malignancies and potential as a therapeutic target in cancer

article

PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma.

scientific article

Plant-derived MINA-05 inhibits human prostate cancer proliferation in vitro and lymph node spread in vivo

scientific article published on April 2007

Plasma adiponectin levels are markedly elevated in imatinib-treated chronic myeloid leukemia (CML) patients: a mechanism for improved insulin sensitivity in type 2 diabetic CML patients?

scientific article published on 13 May 2010

Prospective histomorphometric and DXA evaluation of bone remodeling in imatinib-treated CML patients: evidence for site-specific skeletal effects.

scientific article published on 8 November 2012

SAMSN1 is a tumor suppressor gene in multiple myeloma

scientific article

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress.

scientific article published on 14 April 2017

Suppression of PDGF-induced PI3 kinase activity by imatinib promotes adipogenesis and adiponectin secretion

scientific article published on 2 April 2012

Targeted Disruption of Bone Marrow Stromal Cell-Derived Gremlin1 Limits Multiple Myeloma Disease Progression In Vivo

scientific article published on 03 August 2020

Tetraspanin 7 (TSPAN7) expression is upregulated in multiple myeloma patients and inhibits myeloma tumour development in vivo.

scientific article

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

scientific article published on 17 February 2017

The effect of the dual PI3K and mTOR inhibitor BEZ235 on tumour growth and osteolytic bone disease in multiple myeloma.

scientific article published on 17 September 2014

The tyrosine kinase inhibitor dasatinib (SPRYCEL) inhibits chondrocyte activity and proliferation

scientific article published on February 4, 2011

Therapeutic concentrations of dasatinib inhibit in vitro osteoclastogenesis.

scientific article

Therapeutic targeting of N-cadherin is an effective treatment for multiple myeloma.

scientific article published on 20 July 2015

Tumour Dissemination in Multiple Myeloma Disease Progression and Relapse: A Potential Therapeutic Target in High-Risk Myeloma

scientific article published on 04 December 2020

Twist-1 is upregulated by NSD2 and contributes to tumour dissemination and an epithelial-mesenchymal transition-like gene expression signature in t(4;14)-positive multiple myeloma

scientific article published on 31 January 2020