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List of works by Renae M. Ryan

A channel in a transporter.

scientific article

Allosteric modulation of neurotransmitter transporters at excitatory synapses.

scientific article published in September 2004

Amino Acid Transporters and Exchangers from the SLC1A Family: Structure, Mechanism and Roles in Physiology and Cancer

scientific article published on 24 January 2020

Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways

scientific article

Brain transporters: From genes and genetic disorders to function and drug discovery.

scientific article published in September 2016

Characterization of the Inward- and Outward-Facing Substrate Binding Sites of the Prokaryotic Aspartate Transporter, GltPh

scientific article published on 2 December 2016

Characterizing unexpected interactions of a glutamine transporter inhibitor with members of the SLC1A transporter family

scientific article published in 2022

Correction: Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2.

scientific article published on 19 July 2016

Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

scientific article

Design, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPK.

scientific article

Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain

scientific article published on 20 February 2019

Distinct conformational states mediate the transport and anion channel properties of the glutamate transporter EAAT-1.

scientific article published on 28 January 2002

Effects of sumatriptan on rat medullary dorsal horn neurons.

scientific article

Elevating the alternating-access model

scientific article published in March 2016

Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport

scientific article published on 29 October 2009

Functional characterization of a Na+-dependent aspartate transporter from Pyrococcus horikoshii.

scientific article published on 20 April 2009

Glycine transport inhibitors for the treatment of pain

scientific article published on 21 June 2014

Glycine transporter2 inhibitors: Getting the balance right

scientific article

How and why are channels in transporters?

scientific article

Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2.

scientific article

Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics

scientific article published on 17 October 2019

Lipid inhibitors of high affinity glycine transporters: identification of a novel class of analgesics.

scientific article published on 12 September 2013

Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria

scientific article

Mechanisms of glutamate transport

scientific article

Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2.

scientific article published on 9 November 2017

Molecular determinants for functional differences between alanine-serine-cysteine transporter 1 and other glutamate transporter family members.

scientific article published on 7 February 2013

Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth.

scientific article

Na+ interactions with the neutral amino acid transporter ASCT1.

scientific article

Oleoyl-L-carnitine inhibits glycine transport by GlyT2

scientific article published on February 2013

Position of the third Na+ site in the aspartate transporter GltPh and the human glutamate transporter, EAAT1.

scientific article

Prostaglandin E(2) inhibits calcium current in two sub-populations of acutely isolated mouse trigeminal sensory neurons.

scientific article published in March 2002

Regulation of SLC1A4 and SLC1A5 in Prostate Cancer-Letter

scientific article published on 01 November 2018

Site-directed mutagenesis in the study of membrane transporters

scientific article published in January 2003

Site-directed mutagenesis in the study of membrane transporters

scientific article published in January 2010

Slips, leaks and channels in glutamate transporters

scientific article published on January 2008

Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma.

scientific article

Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.

scientific article

Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2.

scientific article published on 2 June 2017

Synthesis and in vitro evaluation of diverse heterocyclic diphenolic compounds as inhibitors of DYRK1A

scientific article published on 28 October 2018

Targeting glutamine transport to suppress melanoma cell growth.

scientific article published on 17 February 2014

The Split Personality of Glutamate Transporters: A Chloride Channel and a Transporter

scientific article published on 25 August 2015

The amino acid transporter, SLC1A3, is plasma membrane-localised in adipocytes and its activity is insensitive to insulin

scientific article published on 29 December 2016

The chloride permeation pathway of a glutamate transporter and its proximity to the glutamate translocation pathway.

scientific article published on 24 February 2004

The domain interface of the human glutamate transporter EAAT1 mediates chloride permeation

scientific article

The position of an arginine residue influences substrate affinity and K+ coupling in the human glutamate transporter, EAAT1.

scientific article published on 6 May 2010

The role of cation binding in determining substrate selectivity of glutamate transporters

scientific article

The uncoupled chloride conductance of a bacterial glutamate transporter homolog

scientific article published on 15 April 2007

Transport rates of a glutamate transporter homologue are influenced by the lipid bilayer.

scientific article

Tuning the ion selectivity of glutamate transporter-associated uncoupled conductances

scientific article published on 13 June 2016

Water and urea permeation pathways of the human excitatory amino acid transporter EAAT1

scientific article published on 15 October 2011

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