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List of works by Paul G Shiels

25-Hydroxyvitamin D is lower in deprived groups, but is not associated with carotid intima media thickness or plaques: results from pSoBid

scientific article published on 9 May 2012

A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations

scientific article published on 10 November 2011

A candidate gene for human neurodegenerative disorders: a rat PKC gamma mutation causes a Parkinsonian syndrome.

scientific article

A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility

scientific article published on 09 January 2014

A molecular signature for delayed graft function

scientific article published on 09 August 2018

A novel rodent model of severe renal ischemia reperfusion injury

scientific article published on 18 February 2016

A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with Systemic Sclerosis in a large European cohort.

scientific article

A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort

scientific article published on 27 December 2010

Accelerated ageing and renal dysfunction links lower socioeconomic status and dietary phosphate intake

scientific article published on 26 April 2016

Accelerated biological ageing in HIV-infected individuals in South Africa: a case-control study

scientific article published on September 2013

Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort

scientific article

Allostatic load and ageing: linking the microbiome and nutrition with age-related health

scientific article published on 15 August 2019

An MIF Promoter Polymorphism Is Associated with Susceptibility to Pulmonary Arterial Hypertension in Diffuse Cutaneous Systemic Sclerosis.

scientific article

Analysis of telomere length in Dolly, a sheep derived by nuclear transfer.

scientific article

Analysis of telomere lengths in cloned sheep

scientific article

Antigenic variation inTrypanosoma brucei: a telomeric expression site for variant-specific surface glycoprotein genes with novel features ⬇️

scientific article published on April 11, 1991

Assessment of candidate ocular biomarkers of ageing in a South African adult population: relationship with chronological age and systemic biomarkers

scientific article published on 20 May 2013

Association between exposure to second-hand smoke and telomere length: cross-sectional study of 1303 non-smokers

scientific article published on 11 October 2017

Association between telomere length and heart disease in a narrow age cohort of older people

scientific article published on 20 December 2006

Association of a non-synonymous functional variant of the ITGAM gene with systemic sclerosis

article

Below-target postoperative arterial blood pressure but not central venous pressure is associated with delayed graft function.

scientific article

Biological Ageing, Inflammation and Nutrition: How Might They Impact on Systemic Sclerosis?

scientific article published on 27 July 2015

Biological ageing is a key determinant in systemic sclerosis.

scientific article published on 23 November 2011

Breast cancer patients' clinical outcome measures are associated with Src kinase family member expression.

scientific article

Breath ethane peaks during a single haemodialysis session and is associated with time on dialysis

scientific article published on 22 April 2008

CDKN2A might be better than telomere length in determining individual health status ⬇️

scientific article published on 06 March 2012

CDKN2A/p16INK4a expression is associated with vascular progeria in chronic kidney disease.

scientific article published on 9 February 2017

Cardio-metabolic risk factors and cortical thickness in a neurologically healthy male population: Results from the psychological, social and biological determinants of ill health (pSoBid) study

scientific article published on 22 April 2013

Cellular senescence in pretransplant renal biopsies predicts postoperative organ function.

scientific article

Chronic kidney disease and premature ageing

scientific article published on 07 October 2014

Circulating markers of ageing and allostatic load: A slow train coming.

scientific article published on 19 April 2016

Confirmation of CCR6 as a risk factor for anti-topoisomerase I antibodies in systemic sclerosis.

scientific article published on 27 August 2015

Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study

scientific article published on 15 August 2012

Confirmation of association of the macrophage migration inhibitory factor gene with systemic sclerosis in a large European population

article

Corneal endothelial cells provide evidence of accelerated cellular senescence associated with HIV infection: a case-control study

scientific article

Correction: Identification of Molecular Markers of Delayed Graft Function Based on the Regulation of Biological Ageing

scientific article published on 10 March 2016

Correction: Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy.

scientific article published on 25 August 2011

Correction: Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy.

scientific article

Corrigendum to "Cardio-metabolic risk factors and cortical thickness in a neurologically healthy male population: Results from the psychological, social and biological determinants of ill health (pSoBid) study" [Neuroimage Clin. 2 (2013) 646-57].

scientific article published on 22 June 2015

Current epigenetic aspects the clinical kidney researcher should embrace.

scientific article published on 30 June 2017

Deficits in the mid-brain raphe nuclei and striatum of the AS/AGU rat, a protein kinase C-gamma mutant.

scientific article published on December 2005

Differences in atherosclerosis according to area level socioeconomic deprivation: cross sectional, population based study

scientific article published on 27 October 2009

Distinct, developmental stage-specific activation mechanisms of trypanosome VSG genes.

scientific article published in December 1990

Do symptoms of depression predict telomere length? Evidence from the west of Scotland twenty-07 study

scientific article published on 19 March 2013

Dolly, no longer the exception: telomeres and implications for transplantation

scientific article published on 01 January 2003

Duplicative activation mechanisms of two trypanosome telomeric VSG genes with structurally simple 5' flanks.

scientific article published on December 1990

Dynamic study of oxidative stress in renal dialysis patients based on breath ethane measured by optical spectroscopy

scholarly article by Claire S Patterson et al published 1 December 2007 in Journal of Breath Research

Early life socioeconomic adversity is associated in adult life with chronic inflammation, carotid atherosclerosis, poorer lung function and decreased cognitive performance: a cross-sectional, population-based study

scientific article

Early life socioeconomic status, chronic physiological stress and hippocampal N-acetyl aspartate concentrations

scientific article published on 17 August 2012

Erratum: Corrigendum: Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

scholarly article published in Nature Genetics

Exploiting paracrine mechanisms of tissue regeneration to repair damaged organs.

scientific article published on 20 June 2013

Feasibility study of percutaneous transvalvular endomyocardial cryoablation for the treatment of hypertrophic obstructive cardiomyopathy

scientific article published in June 2007

Food as medicine: targeting the uraemic phenotype in chronic kidney disease

scientific article published on 22 September 2020

Gender and telomere length: systematic review and meta-analysis

scientific article published on 21 December 2013

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

scientific article

Identification of Molecular Markers of Delayed Graft Function Based on the Regulation of Biological Ageing.

scientific article published on 6 January 2016

Identification of a novel HaeIII PCR-RFLP in the SLA DQB gene

article

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy

scientific article

Identification of novel genetic markers associated with the clinical phenotypes of systemic sclerosis through a genome wide association strategy

scientific article published on 25 November 2010

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis

scientific article published on January 2014

Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility

scientific article

Improving precision in investigating aging: why telomeres can cause problems.

scientific article published on 10 June 2010

Increased Telomere Attrition After Renal Transplantation-Impact of Antimetabolite Therapy.

scientific article published on 16 November 2016

Inflammation and premature aging in advanced chronic kidney disease

scientific article

Inhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium

scientific article

Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears

scientific article published on 23 November 2020

Interaction of personality traits with social deprivation in determining mental wellbeing and health behaviours.

scientific article published on 2 May 2012

Is Southern blotting necessary to measure telomere length reproducibly? Authors' Response to: Commentary: The reliability of telomere length measurements

scientific article published on 24 September 2015

Is socioeconomic status associated with biological aging as measured by telomere length?

scientific article

Is telomere length a biomarker for aging: cross-sectional evidence from the west of Scotland?

scientific article

Isolation, characterization, and differentiation of thy1.1-sorted pancreatic adult progenitor cell populations

scientific article published on 01 December 2009

KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor

scientific article published on 27 December 2012

Long-lived animals with negligible senescence: clues for ageing research

scientific article published on 31 July 2019

Manipulating the exposome to enable better ageing

scientific article published in 2021

Microvesicles as Vehicles for Tissue Regeneration: Changing of the Guards

scientific article

Microvesicles but Not Exosomes from Pathfinder Cells Stimulate Functional Recovery of the Pancreas in a Mouse Streptozotocin-Induced Diabetes Model

scientific article published on 10 February 2016

New insight on the Xq28 association with systemic sclerosis

scientific article published on 26 February 2013

Nitrones for understanding and ameliorating the oxidative stress associated with aging

scientific article published on December 2009

Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease ⬇️

scientific article published on August 12, 2013

Nutrients and ageing: what can we learn about ageing interactions from animal biology?

scientific article

Ocular parameters of biological ageing in HIV-infected individuals in South Africa: relationship with chronological age and systemic biomarkers of ageing

scientific article published on 27 August 2013

Optimized protocols for typing 75 microsatellite loci in AS, PVG, F344, and BN rats

scientific article published on 01 March 1995

Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey

scientific article published on 14 October 2008

Pancreatic-derived pathfinder cells enable regeneration of critically damaged adult pancreatic tissue and completely reverse streptozotocin-induced diabetes.

scientific article published on 19 March 2011

Pathfinder Cells Provide A Novel Therapeutic Intervention For Acute Kidney Injury ⬇️

scientific article published on February 1, 2013

Personality, socio-economic status and inflammation: cross-sectional, population-based study

scientific article

Planetary Health, Nutrition and Chronic Kidney Disease: Connecting the Dots for a Sustainable Future

scientific article published in 2022

Postinjury vascular intimal hyperplasia in mice is completely inhibited by CD34+ bone marrow-derived progenitor cells expressing membrane-tethered anticoagulant fusion proteins

scientific article published on 27 June 2006

Pre-transplant CDKN2A expression in kidney biopsies predicts renal function and is a future component of donor scoring criteria

scientific article

Premature aging in chronic kidney disease and chronic obstructive pulmonary disease: similarities and differences.

scientific article published on 12 September 2015

Psychological, social and biological determinants of ill health (pSoBid): study protocol of a population-based study

scientific article

Reproducibility of Telomere Length Assessment--An International Collaborative Study

scientific article published on 24 September 2015

Reproducibility of telomere length assessment: Authors' Response to Damjan Krstajic and Ljubomir Buturovic

scientific article published on 24 September 2015

Reproducibility of telomere length assessment: an international collaborative study

scientific article published on 19 September 2014

SIRT2: tumour suppressor or tumour promoter in operable breast cancer?

scientific article

SIRT3 & SIRT7: Potential Novel Biomarkers for Determining Outcome in Pancreatic Cancer Patients.

scientific article published on 29 June 2015

Segmental Aging Underlies the Development of a Parkinson Phenotype in the AS/AGU Rat.

scientific article published on 17 October 2016

Senescent phenotypes and telomere lengths of peripheral blood T-cells mobilized by acute exercise in humans

scientific article published in January 2010

Simvastatin inhibits lymphocyte function in normal subjects and patients with cardiovascular disease.

scientific article

Sirtuins, bioageing, and cancer.

scientific article published on 30 June 2011

Socio-economic status is associated with epigenetic differences in the pSoBid cohort

article

Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes?

scientific article

Telomere Attrition and Elongation after Chronic Dialysis Initiation in Patients with End-Stage Renal Disease

scientific article published on 20 October 2015

Telomere Biology Alterations as a Mortality Risk Factor in CKD

scientific article published in June 2008

Telomere attrition and decreased fetuin-A levels indicate accelerated biological aging and are implicated in the pathogenesis of colorectal cancer

scientific article published on 13 July 2011

Telomere attrition is associated with inflammation, low fetuin-A levels and high mortality in prevalent haemodialysis patients.

scientific article published on 7 December 2007

Telomere biology is differently affected within clinical subsets of systemic sclerosis and points towards different downstream defects

Telomere length and physical performance at older ages: an individual participant meta-analysis

scientific article

Telomeres, ageing and oxidation.

scientific article published in January 2009

The association between telomere length, physical health, cognitive ageing, and mortality in non-demented older people.

scientific article

The cystatin S gene maps to rat chromosome 3, to which D1mgh18 is re-assigned from chromosome 1

scientific article published on 01 December 1997

The eye as a model of ageing in translational research – Molecular, epigenetic and clinical aspects ⬇️

scientific article published on December 27, 2012

The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism

scientific article

The in situ local immune response, tumour senescence and proliferation in colorectal cancer.

scientific article published on 10 September 2013

The role of epigenetics in renal ageing.

scientific article

The role of the microbiota in sedentary lifestyle disorders and ageing: lessons from the animal kingdom

scientific article published on 05 February 2020

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis.

scientific article

The use of telomere biology to identify and develop superior nitrone based anti-oxidants

scientific article

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