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List of works by Martin Kampmann

A CRISPR Approach to Neurodegenerative Diseases

scientific article published on 4 May 2017

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility

scientific article

Biochemistry. Nascent proteins caught in the act.

scientific article published in December 2009

CRISPR-based functional genomics for neurological disease

scientific article published on 08 July 2020

CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine

scientific article

CRISPulator: A Discrete Simulation Tool For Pooled Genetic Screens

CRISPulator: a discrete simulation tool for pooled genetic screens

scientific article

Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether

scientific article published on 31 May 2019

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.

scientific article

Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation

scientific article published on 02 October 2019

Conserved spatial organization of FG domains in the nuclear pore complex

scientific article published on 8 January 2013

Deep mutational scanning reveals the structural basis for α-synuclein activity

scientific article published on 09 March 2020

Defining the ATPome reveals cross-optimization of metabolic pathways

scientific article published on 28 August 2020

Dual gene activation and knockout screen reveals directional dependencies in genetic networks

scientific article published on 15 January 2018

Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells

scientific article published on 10 May 2017

Facilitated diffusion in chromatin lattices: mechanistic diversity and regulatory potential.

scientific article

Fluorescence anisotropy reveals order and disorder of protein domains in the nuclear pore complex

scientific article

Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps

scientific article

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

scientific article

Heterochromatin anomalies and double-stranded RNA accumulation underlie poly(PR) toxicity

article

Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells

scientific article

Knocking out the door to tunicamycin entry

scientific article

LRP1 is a master regulator of tau uptake and spread

scientific article published on 01 April 2020

Mapping the orientation of nuclear pore proteins in living cells with polarized fluorescence microscopy

scientific article

Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway

scientific article published on 04 March 2020

Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease

scientific article published in 2021

Neurodegeneration enters the era of functional genomics

scientific article published on 07 September 2023

Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens

scientific article

Obstacle bypass in protein motion along DNA by two-dimensional rather than one-dimensional sliding

scientific article

Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits

scientific article

Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification

scientific article

Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response

scientific article published on 15 April 2015

Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model

scientific article published on 06 May 2022

Relapse-associated AURKB blunts the glucocorticoid sensitivity of B cell acute lymphoblastic leukemia

scientific article published on 07 February 2019

Reverse gyrase has heat-protective DNA chaperone activity independent of supercoiling

scientific article published on 6 July 2004

Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding

scientific article published on 12 August 2020

Structure of a trimeric nucleoporin complex reveals alternate oligomerization states

scientific article

Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia

scientific article

Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs).

scientific article

Three-dimensional structure and flexibility of a membrane-coating module of the nuclear pore complex

scientific article published on 7 June 2009

Unraveling the mechanism of cell death induced by chemical fibrils

scientific article

Use of RNA tertiary interaction modules for the crystallisation of the spliceosomal snRNP core domain.

scientific article published on 17 July 2010

Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer

scientific article

Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs

scientific article

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