List of works - Linda Columbus

A Multifrequency Electron Spin Resonance Study of T4 Lysozyme Dynamics Using the Slowly Relaxing Local Structure Model

article

A broad specificity nucleoside kinase from Thermoplasma acidophilum

scientific article

A new spin on protein dynamics

scientific article published in June 2002

Analysis of small-angle X-ray scattering data of protein–detergent complexes by singular value decomposition

Backbone ¹H, ¹³C and ¹⁵N resonance assignments of the α-helical membrane protein TM0026 from Thermotoga maritima

scientific article

Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s

scientific article

Cottrell Scholars Collaborative New Faculty Workshop: Professional Development for New Chemistry Faculty and Initial Assessment of Its Efficacy

article

Dependence of micelle size and shape on detergent alkyl chain length and head group

scientific article

Endothelial cell expression of haemoglobin α regulates nitric oxide signalling

scientific article

Endothelial nitric oxide synthase in the microcirculation

scientific article

Expression, purification, and characterization of Thermotoga maritima membrane proteins for structure determination

scientific article

Hemoglobin α in the blood vessel wall

scientific article

Hemoglobin α/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction

scientific article

Heterocellular Contact Can Dictate Arterial Function

scientific article published on 01 May 2019

Identification and removal of nitroxide spin label contaminant: impact on PRE studies of α-helical membrane proteins in detergent

scientific article

Identification of Key Structural Features Determining the Binding of Alpha Globin and Endothelial Nitric Oxide Synthase

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane

scientific article

Imaging Flow Cytometry Analysis of CEACAM Binding to Opa-Expressing Neisseria gonorrhoeae

scientific article published on 02 June 2020

Investigating the Relationship Between Physical Properties of Detergents and Membrane Protein Structure Determination

Known structure, unknown function: An inquiry-based undergraduate biochemistry laboratory course

scientific article

Label-free method for cell counting in crude biological samples via paramagnetic bead aggregation

scientific article

Low- q Bicelles Are Mixed Micelles

scientific article

MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation

scientific article

Mapping backbone dynamics in solution with site-directed spin labeling: GCN4-58 bZip free and bound to DNA.

scientific article

Mapping membrane protein backbone dynamics: a comparison of site-directed spin labeling with NMR 15N-relaxation measurements

scientific article

Membrane Proteins: Properties

article

Mixing and Matching Detergents for Membrane Protein NMR Structure Determination

Mixing and matching detergents for membrane protein NMR structure determination

scientific article

Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbαX).

scientific article

Modulating the Physical Properties of Micelles for Membrane Protein Investigations

Molecular motion of spin labeled side chains in alpha-helices: analysis by variation of side chain structure

scientific article published in April 2001

NMR Backbone Assignment of Opai: A Mediator of Host:Neisseria Interactions

NMR Solution Structure of Opa60: A Neisserial Membrane Protein that Mediates Host Phagocytosis

NMR structure determination of the conserved hypothetical protein TM1816 from Thermotoga maritima

scientific article

Neisserial Opa Protein-CEACAM Interactions: Competition for Receptors as a Means of Bacterial Invasion and Pathogenesis

scientific article

Opa+ Neisseria gonorrhoeae exhibits reduced survival in human neutrophils via Src family kinase-mediated bacterial trafficking into mature phagolysosomes

scientific article

Physical determinants of β-barrel membrane protein folding in lipid vesicles

scientific article

Post-expression strategies for structural investigations of membrane proteins

scientific article

Protein global fold determination using site-directed spin and isotope labeling

scientific article

Quantifying Carcinoembryonic Antigen-like Cell Adhesion Molecule-Targeted Liposome Delivery Using Imaging Flow Cytometry

scientific article published on 13 May 2019

Refinement of highly flexible protein structures using simulation-guided spectroscopy

Size and shape of detergent micelles determined by small-angle X-ray scattering

scientific article published on 9 October 2007

Solution NMR Structure Determination of Polytopic α-Helical Membrane Proteins: A Guide to Spin Label Paramagnetic Relaxation Enhancement Restraints

scientific article

Solution NMR resonance assignment strategies for β-barrel membrane proteins

scientific article

Strategies for the Solution NMR Structure Determination of Beta-Barrel Membrane Proteins

Structural Investigations of Inclusion Membrane Protein a (INCA) of Chlamydia Trachomatis

Structural origins of nitroxide side chain dynamics on membrane protein α-helical sites

scientific article

Structure and ligand binding of the soluble domain of a Thermotoga maritima membrane protein of unknown function TM1634.

scientific article

Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation

scientific article

Structure of the KcsA potassium channel from Streptomyces lividans: a site-directed spin labeling study of the second transmembrane segment

scientific article published on August 1999

Structure of the Neisserial outer membrane protein Opa₆₀: loop flexibility essential to receptor recognition and bacterial engulfment

scientific article

The COMBREX project: design, methodology, and initial results

scientific article

The Fluidity of Phosphocholine and Maltoside Micelles and the Effect of CHAPS

scientific article published on 30 March 2019

The Spontaneous Refolding of Opacity-Associated Proteins into Lipid Membranes

Tuning Micelle Dimensions and Properties for Stabilizing Membrane Protein Fold and Function

Tuning micelle dimensions and properties with binary surfactant mixtures

scientific article

List of works by Linda Columbus

A Multifrequency Electron Spin Resonance Study of T4 Lysozyme Dynamics Using the Slowly Relaxing Local Structure Model

A broad specificity nucleoside kinase from Thermoplasma acidophilum

A new spin on protein dynamics

Analysis of small-angle X-ray scattering data of protein–detergent complexes by singular value decomposition

Backbone ¹H, ¹³C and ¹⁵N resonance assignments of the α-helical membrane protein TM0026 from Thermotoga maritima

Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s

Cottrell Scholars Collaborative New Faculty Workshop: Professional Development for New Chemistry Faculty and Initial Assessment of Its Efficacy

Dependence of micelle size and shape on detergent alkyl chain length and head group

Endothelial cell expression of haemoglobin α regulates nitric oxide signalling

Endothelial nitric oxide synthase in the microcirculation

Expression, purification, and characterization of Thermotoga maritima membrane proteins for structure determination

Hemoglobin α in the blood vessel wall

Hemoglobin α/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction

Heterocellular Contact Can Dictate Arterial Function

Identification and removal of nitroxide spin label contaminant: impact on PRE studies of α-helical membrane proteins in detergent

Identification of Key Structural Features Determining the Binding of Alpha Globin and Endothelial Nitric Oxide Synthase

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane

Imaging Flow Cytometry Analysis of CEACAM Binding to Opa-Expressing Neisseria gonorrhoeae

Investigating the Relationship Between Physical Properties of Detergents and Membrane Protein Structure Determination

Known structure, unknown function: An inquiry-based undergraduate biochemistry laboratory course

Label-free method for cell counting in crude biological samples via paramagnetic bead aggregation

Low- q Bicelles Are Mixed Micelles

MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation

Mapping backbone dynamics in solution with site-directed spin labeling: GCN4-58 bZip free and bound to DNA.

Mapping membrane protein backbone dynamics: a comparison of site-directed spin labeling with NMR 15N-relaxation measurements

Membrane Proteins: Properties

Mixing and Matching Detergents for Membrane Protein NMR Structure Determination

Mixing and matching detergents for membrane protein NMR structure determination

Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbαX).

Modulating the Physical Properties of Micelles for Membrane Protein Investigations

Molecular motion of spin labeled side chains in alpha-helices: analysis by variation of side chain structure

NMR Backbone Assignment of Opai: A Mediator of Host:Neisseria Interactions

NMR Solution Structure of Opa60: A Neisserial Membrane Protein that Mediates Host Phagocytosis

NMR structure determination of the conserved hypothetical protein TM1816 from Thermotoga maritima

Neisserial Opa Protein-CEACAM Interactions: Competition for Receptors as a Means of Bacterial Invasion and Pathogenesis

Opa+ Neisseria gonorrhoeae exhibits reduced survival in human neutrophils via Src family kinase-mediated bacterial trafficking into mature phagolysosomes

Physical determinants of β-barrel membrane protein folding in lipid vesicles

Post-expression strategies for structural investigations of membrane proteins

Protein global fold determination using site-directed spin and isotope labeling

Quantifying Carcinoembryonic Antigen-like Cell Adhesion Molecule-Targeted Liposome Delivery Using Imaging Flow Cytometry

Refinement of highly flexible protein structures using simulation-guided spectroscopy

Size and shape of detergent micelles determined by small-angle X-ray scattering

Solution NMR Structure Determination of Polytopic α-Helical Membrane Proteins: A Guide to Spin Label Paramagnetic Relaxation Enhancement Restraints

Solution NMR resonance assignment strategies for β-barrel membrane proteins

Strategies for the Solution NMR Structure Determination of Beta-Barrel Membrane Proteins

Structural Investigations of Inclusion Membrane Protein a (INCA) of Chlamydia Trachomatis

Structural origins of nitroxide side chain dynamics on membrane protein α-helical sites

Structure and ligand binding of the soluble domain of a Thermotoga maritima membrane protein of unknown function TM1634.

Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation

Structure of the KcsA potassium channel from Streptomyces lividans: a site-directed spin labeling study of the second transmembrane segment

Structure of the Neisserial outer membrane protein Opa₆₀: loop flexibility essential to receptor recognition and bacterial engulfment

The COMBREX project: design, methodology, and initial results

The Fluidity of Phosphocholine and Maltoside Micelles and the Effect of CHAPS

The Spontaneous Refolding of Opacity-Associated Proteins into Lipid Membranes

Tuning Micelle Dimensions and Properties for Stabilizing Membrane Protein Fold and Function

Tuning micelle dimensions and properties with binary surfactant mixtures