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List of works by Miguel López-Botet

A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells

scientific article

Adaptive NKG2C+ NK Cell Response and the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.

scientific article

Adaptive natural killer cell response to cytomegalovirus and disability progression in multiple sclerosis.

scientific article published on 11 September 2015

Adaptive reconfiguration of the human NK‐cell compartment in response to cytomegalovirus: A different perspective of the host‐pathogen interaction ⬇️

scientific article published on May 1, 2013

Analysis of expression and function of the inhibitory receptor ILT2 (CD85j/LILRB1/LIR-1) in peripheral blood mononuclear cells from patients with systemic lupus erythematosus (SLE).

scientific article

Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing αβ+T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies

scientific article published on 11 December 2015

Antibody-Dependent NK Cell Activation Differentially Targets EBV-Infected Cells in Lytic Cycle and Bystander B Lymphocytes Bound to Viral Antigen-Containing Particles

scientific article published on 19 June 2017

Antibody-mediated response of NKG2Cbright NK cells against human cytomegalovirus.

scientific article

Assessment of copy-number variation in the NKG2C receptor gene in a single-tube and characterization of a reference cell panel, using standard polymerase chain reaction.

scientific article

Assessment of neuronal autoantibodies in patients with small cell lung cancer treated with chemotherapy with or without ipilimumab.

scientific article published on 27 November 2017

Association of Atherosclerosis With Expression of the LILRB1 Receptor By Human NK and T-Cells Supports the Infectious Burden Hypothesis

scientific article published on 04 August 2011

CD2 is involved in regulating cyclic AMP levels in T cells

scientific article published on 01 June 1988

CMV and Immunosenescence: from basics to clinics

scientific article published on 31 October 2012

Circulating NK-cell subsets in renal allograft recipients with anti-HLA donor-specific antibodies.

scientific article published on 5 February 2015

Cloning of two new splice variants of Siglec-10 and mapping of the interaction between Siglec-10 and SHP-1.

scientific article

Concentrations of cyclosporin A and FK506 that inhibit IL-2 induction in human T cells do not affect TGF-beta1 biosynthesis, whereas higher doses of cyclosporin A trigger apoptosis and release of preformed TGF-beta1.

scientific article

Control of self‐reactive cytotoxic T lymphocytes expressing γδ T cell receptors by natural killer inhibitory receptors ⬇️

scientific article published on November 1, 1997

Costimulation of cAMP and Protein Kinase C Pathways Inhibits the CD3-Dependent T Cell Activation and Leads to a Persistent Expression of the AP-1 Transcription Factor

scientific article published on 01 July 1993

Daratumumab in combination with urelumab to potentiate anti-myeloma activity in lymphocyte-deficient mice reconstituted with human NK cells

scientific article published on 13 April 2019

Development of the adaptive NK cell response to human cytomegalovirus in the context of aging.

scientific article published on 24 June 2016

Differential effects of US2, US6 and US11 human cytomegalovirus proteins on HLA class Ia and HLA-E expression: impact on target susceptibility to NK cell subsets

scientific article published on October 2003

Differential expression of inhibitory and activating CD94/NKG2 receptors on NK cell clones

scientific article published on June 2002

Dual Role of Natural Killer Cells on Graft Rejection and Control of Cytomegalovirus Infection in Renal Transplantation.

scientific article published on 16 February 2017

Dynamics of the NK-cell subset redistribution induced by cytomegalovirus infection in preterm infants

scientific article published on 27 January 2015

Elusive Role of the CD94/NKG2C NK Cell Receptor in the Response to Cytomegalovirus: Novel Experimental Observations in a Reporter Cell System.

scientific article published on 24 October 2017

Expansion of CD94/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts.

scientific article published on 29 December 2005

Expansion of the NKG2C+ natural killer-cell subset is associated with high-risk carotid atherosclerotic plaques in seropositive patients for human cytomegalovirus.

scientific article published on 22 August 2013

Expression and function of NKG2D in CD4+ T cells specific for human cytomegalovirus.

scientific article published on December 2006

Expression and function of alpha4/beta7 integrin on human natural killer cells

article

Expression of Lymphocyte Activation Surface Antigens in Bronchoalveolar Lavage and Peripheral Blood Cells From Young Healthy Subjects

scientific article published on 01 July 1993

Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells.

scientific article

Functional analysis of α1β1 integrin in human natural killer cells

article

Functional impact of A91V mutation of the PRF1 perforin gene.

scientific article

Gender-associated differences of perforin polymorphisms in the susceptibility to multiple sclerosis

scientific article

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

scientific article

High Numbers of Circulating CD57+ NK Cells Associate with Resistance to HER2-Specific Therapeutic Antibodies in HER2+ Primary Breast Cancer

scientific article published on 12 June 2019

High toxic efficiency of ricin immunotoxins specific for the T-cell antigen receptor of a human leukemia T-cell line.

scientific article published in April 1989

Host Genetic Factors in Susceptibility to Herpes Simplex Type 1 Virus Infection: Contribution of Polymorphic Genes at the Interface of Innate and Adaptive Immunity ⬇️

scientific article published on April 4, 2012

Human Cytomegalovirus Antigen Presentation by HLA-DR+ NKG2C+ Adaptive NK Cells Specifically Activates Polyfunctional Effector Memory CD4+ T Lymphocytes

scientific article published on 03 April 2019

Human T cell receptor-mediated recognition of HLA-E.

scientific article

Human cytomegalovirus and natural killer-mediated surveillance of HLA class I expression: a paradigm of host-pathogen adaptation.

scientific article

Human cytomegalovirus infection is associated with increased proportions of NK cells that express the CD94/NKG2C receptor in aviremic HIV-1-positive patients.

scientific article published on 24 May 2006

Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles

scientific article

IL-12-dependent inducible expression of the CD94/NKG2A inhibitory receptor regulates CD94/NKG2C+ NK cell function

scientific article

IREM-1 is a novel inhibitory receptor expressed by myeloid cells

scientific article

Identification of Natural Killer (NK) Cells in Lesions of Human Cutaneous Graft-Versus-Host Disease: Expression of a Novel NK-Associated Surface Antigen (Kp43) in Mononuclear Infiltrates

scientific article published on 01 October 1991

Impact of Zygosity on Bimodal Phenotype Distributions.

scientific article published on July 2017

Imprint of human cytomegalovirus infection on the NK cell receptor repertoire

scientific article published on 10 August 2004

Induction of natural killer-like cytotoxicity in cultured human thymocytes

scientific article published on 01 December 1983

Influence of congenital human cytomegalovirus infection and the NKG2C genotype on NK-cell subset distribution in children

Influence of human cytomegalovirus infection on the NK cell receptor repertoire in children

Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection

article

Innate T-cell immunity to nonpeptidic antigens.

scientific article published in June 1998

Interaction of the LILRB1 inhibitory receptor with HLA class Ia dimers

scientific article published on 24 April 2016

Interleukin 2 and interferon-γ are not sufficient to induce natural killer-like activity in human T cell clones

scientific article published on 01 December 1984

Interplay between Natural Killer Cells and Anti-HER2 Antibodies: Perspectives for Breast Cancer Immunotherapy.

scientific article published on 13 November 2017

Intrahepatic enhanced expression of beta2-microglobulin conformational epitope in acute liver allograft rejection: evidence of modulation by glucocorticoids

scientific article published on August 1, 1998

KIR2DL5: An Orphan Inhibitory Receptor Displaying Complex Patterns of Polymorphism and Expression.

scientific article

Long-Term Redistribution of Peripheral Lymphocyte Subpopulations after Switching from Calcineurin to mTOR Inhibitors in Kidney Transplant Recipients

scientific article published on 11 April 2020

MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine.

scientific article published on 24 January 2011

Molecular characterization of a novel immune receptor restricted to the monocytic lineage

scientific journal article

Molecular studies and NK cell function of a new case of TAP2 homozygous human deficiency

scientific article

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

scientific article published on 7 May 2009

Mutational analysis of immunoreceptor tyrosine-based inhibition motifs of the Ig-like transcript 2 (CD85j) leukocyte receptor

scientific article

NK Cell Infiltrates and HLA Class I Expression in Primary HER2+ Breast Cancer Predict and Uncouple Pathological Response and Disease-free Survival

scientific article published on 06 December 2018

NK Cell and Ig Interplay in Defense against Herpes Simplex Virus Type 1: Epistatic Interaction of CD16A and IgG1 Allotypes of Variable Affinities Modulates Antibody-Dependent Cellular Cytotoxicity and Susceptibility to Clinical Reactivation.

scientific article published on 15 July 2015

NK cell mediated recognition of HLA class Ib molecules: role of CD94/NKG2 receptors.

scientific article

NK receptors: tools for a polyvalent cell family

scientific article published on 3 December 2014

NKG2C zygosity influences CD94/NKG2C receptor function and the NK-cell compartment redistribution in response to human cytomegalovirus

scientific article published on 9 October 2013

NKp46 and DNAM-1 NK-cell receptors drive the response to human cytomegalovirus-infected myeloid dendritic cells overcoming viral immune evasion strategies

article

Natural Killer Cell-Based Immunotherapy in Acute Myeloid Leukemia: Lessons for the Future

scientific article published on 22 February 2016

Natural Killer-like Cytotoxicity of Human T-Cell Clones against Various Target Cells

scientific article published on 01 January 1983

Natural killer cell activation and inhibition by receptors for MHC class I.

scientific article

Natural killer cell phenotype and clinical response to interferon-beta therapy in multiple sclerosis

article

Natural killer cell receptor expression reflects the role of human cytomegalovirus in the pathogenesis of a subset of CD4+ T-cell large granular lymphocytosis ⬇️

scientific article published on December 13, 2010

Natural killer cell receptors for major histocompatibility complex class I and related molecules in cytomegalovirus infection.

scientific article published on March 2004

Natural killer cell-mediated response to human cytomegalovirus-infected macrophages is modulated by their functional polarization

article

New advances in CMV and immunosenescence

scientific article

New nomenclature for MHC receptors.

scientific article

Paired inhibitory and triggering NK cell receptors for HLA class I molecules.

scientific article

Peripheral blood lymphocyte subsets change after steroid withdrawal in renal allograft recipients: a prospective study

scientific article published on 15 May 2019

Pretransplant adaptive NKG2C+ NK cells protect against cytomegalovirus infection in kidney transplant recipients

scientific article published on 19 November 2019

Priming of NK cell anti-viral effector mechanisms by direct recognition of human cytomegalovirus

scientific article published on 21 February 2013

Prostaglandin E2 and the increase of intracellular cAMP inhibit the expression of interleukin 2 receptors in human T cells

scientific article published on 01 November 1988

Recruitment of C-terminal Src kinase by the leukocyte inhibitory receptor CD85j.

scientific article published in November 2004

Relationship of NKG2C Copy Number with the Distribution of Distinct Cytomegalovirus-Induced Adaptive NK Cell Subsets.

scientific article

Removal of PHA from supernatants containing T-cell growth factor

scientific article published on 01 January 1981

Selection and characterization of monoclonal antibodies to the idiotype-like structure of an interleukin-2-producing human leukemia t-cell line

scientific article published on 01 August 1985

Selective expansion of intraepithelial lymphocytes expressing the HLA-E–specific natural killer receptor CD94 in celiac disease

article

Serum cytokine levels as predictive biomarkers of benefit from ipilimumab in small cell lung cancer

scientific article published on 27 March 2019

Signaling through the LFA-1 leucocyte integrin actively regulates intercellular adhesion and tumor necrosis factor-alpha production in natural killer cells.

scientific article published on August 1993

Signalling via CD70, a member of the TNF family, regulates T cell functions

scientific article published on July 2004

Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: evidence for receptor function in heterologous transfectants ⬇️

scientific article published on April 1, 1998

Structure and function of the CD94 C-type lectin receptor complex involved in recognition of HLA class I molecules.

scientific article published on February 1997

Structure of the human CD94 C-type lectin gene

scientific article

Targeting NK-cell checkpoints for cancer immunotherapy

scientific article published on 22 February 2017

The CD94 and NKG2-A C-type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules

scientific article published on 01 February 1997

The CD94/NKG2C killer lectin-like receptor constitutes an alternative activation pathway for a subset of CD8+ T cells

scientific article

The CD94/NKG2C+ NK-cell subset on the edge of innate and adaptive immunity to human cytomegalovirus infection

scientific article published on 22 March 2014

The IREM-1 (CD300f) inhibitory receptor associates with the p85alpha subunit of phosphoinositide 3-kinase

scientific article

The human cytomegalovirus-specific UL1 gene encodes a late-phase glycoprotein incorporated in the virion envelope

scientific article

The human natural killer gene complex is located on chromosome 12p12-p13

scientific article (publication date: 1997)

The tyrosine kinase PYK-2/RAFTK regulates natural killer (NK) cell cytotoxic response, and is translocated and activated upon specific target cell recognition and killing

scientific article

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