List of works - Mitsuharu Hattori

Aberrant fragment of Dab1 protein is present in yotari mouse.

scientific article published on 19 August 2014

Alkaline phosphatase fusions of ligands or receptors as in situ probes for staining of cells, tissues, and embryos

scientific article published on 01 January 2000

Analysis of lissencephaly-causingLIS1mutations

article

Binding of pleckstrin homology domains to WD40/beta-transducin repeat containing segments of the protein product of the Lis-1 gene

scientific article

Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer

scientific article

CUB and Sushi multiple domains 3 regulates dendrite development.

scientific article

Cleavage within Reelin repeat 3 regulates the duration and range of the signaling activity of Reelin protein

scientific article

Cloning and expression of a cDNA encoding the beta-subunit (30-kDa subunit) of bovine brain platelet-activating factor acetylhydrolase

scientific article published in December 1995

Cluster formation of inositol 1,4,5-trisphosphate receptor requires its transition to open state.

scientific article published on 6 December 2004

Detachment of chain-forming neuroblasts by Fyn-mediated control of cell-cell adhesion in the postnatal brain.

scientific article published on 16 April 2018

Determination of cleavage site of Reelin between its sixth and seventh repeat and contribution of meprin metalloproteases to the cleavage.

scientific article published on 21 October 2015

Differential localization of sphingomyelin synthase isoforms in neurons regulates sphingomyelin cluster formation.

scientific article

Differential tissue distribution of the beta- and gamma-subunits of human cytosolic platelet-activating factor acetylhydrolase (isoform I)

scientific article

Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages.

scientific article published in August 2009

Functions of Reelin in cortical neuron migration

scientific article published in February 2016

IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice

scientific article published on 04 October 2013

Importance of Reelin C-terminal region in the development and maintenance of the postnatal cerebral cortex and its regulation by specific proteolysis.

scientific article published in March 2015

Intracellular PAF-Acetylhydrolase Type I.

scientific article published on 4 November 2015

Kinesin dependent, rapid, bi-directional transport of ER sub-compartment in dendrites of hippocampal neurons

scientific article

Mechanism and significance of specific proteolytic cleavage of Reelin

scientific article published on 21 January 2009

Mice that lack the C-terminal region of Reelin exhibit behavioral abnormalities related to neuropsychiatric disorders.

scientific article

Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.

scientific article

Molecular mechanism and physiological significance of proteolytic cleavage of Reelin

scientific article published on October 2010

PAF and PAF acetylhydrolase in the nervous system

scientific article published on September 1996

Platelet-activating factor acetylhydrolase expression and activity suggest a link between neuronal migration and platelet-activating factor

scientific journal article

Re-evaluation of protease activity of reelin.

scientific article

Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1

scientific article

Reelin dysfunction in neuropsychiatric diseases and its potential as a drug target ⬇️

scientific article published on March 1, 2012

Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner

scientific article published on 02 October 2020

Reelin-dependent ApoER2 downregulation uncouples newborn neurons from progenitor cells

scientific article published on 11 October 2012

Regulated cleavage of a contact-mediated axon repellent

scientific article (publication date: 25 August 2000)

Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1

scientific article

Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin.

scientific article published on 17 February 2017

Splicing variations in the ligand-binding domain of ApoER2 results in functional differences in the binding properties to Reelin

scientific article published on 9 January 2009

Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors

scientific article

Structure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomography

scientific article

Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44

scientific journal article

Targeted disruption of intracellular type I platelet activating factor-acetylhydrolase catalytic subunits causes severe impairment in spermatogenesis

scientific journal article

The C-terminal region of Reelin is necessary for proper positioning of a subset of Purkinje cells in the postnatal cerebellum

scientific article published on 29 August 2016

The N-terminal fragment of Reelin is generated after endocytosis and released through the pathway regulated by Rab11.

scientific article

The Secreted Glycoprotein Reelin Suppresses the Proliferation and Regulates the Distribution of Oligodendrocyte Progenitor Cells in the Embryonic Neocortex

scientific article published on 10 September 2020

The regulatory domain of the inositol 1,4,5-trisphosphate receptor is necessary to keep the channel domain closed: possible physiological significance of specific cleavage by caspase 3.

scientific article published on January 2004

Type 1 inositol trisphosphate receptor regulates cerebellar circuits by maintaining the spine morphology of purkinje cells in adult mice

scientific article published in July 2013

cDNA cloning of human cytosolic platelet-activating factor acetylhydrolase gamma-subunit and its mRNA expression in human tissues

scientific article

List of works by Mitsuharu Hattori

Aberrant fragment of Dab1 protein is present in yotari mouse.

Alkaline phosphatase fusions of ligands or receptors as in situ probes for staining of cells, tissues, and embryos

Analysis of lissencephaly-causingLIS1mutations

Binding of pleckstrin homology domains to WD40/beta-transducin repeat containing segments of the protein product of the Lis-1 gene

Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer

CUB and Sushi multiple domains 3 regulates dendrite development.

Cleavage within Reelin repeat 3 regulates the duration and range of the signaling activity of Reelin protein

Cloning and expression of a cDNA encoding the beta-subunit (30-kDa subunit) of bovine brain platelet-activating factor acetylhydrolase

Cluster formation of inositol 1,4,5-trisphosphate receptor requires its transition to open state.

Detachment of chain-forming neuroblasts by Fyn-mediated control of cell-cell adhesion in the postnatal brain.

Determination of cleavage site of Reelin between its sixth and seventh repeat and contribution of meprin metalloproteases to the cleavage.

Differential localization of sphingomyelin synthase isoforms in neurons regulates sphingomyelin cluster formation.

Differential tissue distribution of the beta- and gamma-subunits of human cytosolic platelet-activating factor acetylhydrolase (isoform I)

Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages.

Functions of Reelin in cortical neuron migration

IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice

Importance of Reelin C-terminal region in the development and maintenance of the postnatal cerebral cortex and its regulation by specific proteolysis.

Intracellular PAF-Acetylhydrolase Type I.

Kinesin dependent, rapid, bi-directional transport of ER sub-compartment in dendrites of hippocampal neurons

Mechanism and significance of specific proteolytic cleavage of Reelin

Mice that lack the C-terminal region of Reelin exhibit behavioral abnormalities related to neuropsychiatric disorders.

Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.

Molecular mechanism and physiological significance of proteolytic cleavage of Reelin

PAF and PAF acetylhydrolase in the nervous system

Platelet-activating factor acetylhydrolase expression and activity suggest a link between neuronal migration and platelet-activating factor

Re-evaluation of protease activity of reelin.

Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1

Reelin dysfunction in neuropsychiatric diseases and its potential as a drug target ⬇️

Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner

Reelin-dependent ApoER2 downregulation uncouples newborn neurons from progenitor cells

Regulated cleavage of a contact-mediated axon repellent

Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1

Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin.

Splicing variations in the ligand-binding domain of ApoER2 results in functional differences in the binding properties to Reelin

Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors

Structure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomography

Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44

Targeted disruption of intracellular type I platelet activating factor-acetylhydrolase catalytic subunits causes severe impairment in spermatogenesis

The C-terminal region of Reelin is necessary for proper positioning of a subset of Purkinje cells in the postnatal cerebellum

The N-terminal fragment of Reelin is generated after endocytosis and released through the pathway regulated by Rab11.

The Secreted Glycoprotein Reelin Suppresses the Proliferation and Regulates the Distribution of Oligodendrocyte Progenitor Cells in the Embryonic Neocortex

The regulatory domain of the inositol 1,4,5-trisphosphate receptor is necessary to keep the channel domain closed: possible physiological significance of specific cleavage by caspase 3.

Type 1 inositol trisphosphate receptor regulates cerebellar circuits by maintaining the spine morphology of purkinje cells in adult mice

cDNA cloning of human cytosolic platelet-activating factor acetylhydrolase gamma-subunit and its mRNA expression in human tissues