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List of works by Werner Brack

A Data Set of 255,000 Randomly Selected and Manually Classified Extracted Ion Chromatograms for Evaluation of Peak Detection Methods

scientific article published on 22 April 2020

A bioassay-directed method for the separation of volatile compounds from landfill leachates

A large scale multi-laboratory suspect screening of pesticide metabolites in human biomonitoring: From tentative annotations to verified occurrences

scientific article published in October 2022

A new risk assessment approach for the prioritization of 500 classical and emerging organic microcontaminants as potential river basin specific pollutants under the European Water Framework Directive

scientific article published in May 2011

A sediment extraction and cleanup method for wide-scope multitarget screening by liquid chromatography-high-resolution mass spectrometry

scientific article

Accelerated membrane-assisted clean-up as a tool for the clean-up of extracts from biological tissues

scientific article published on 3 May 2008

Adaptation of Gammarus pulex to agricultural insecticide contamination in streams.

scientific article

An expanded conceptual framework for solution-focused management of chemical pollution in European waters

scientific article published on 09 March 2017

Anthropogenic stressors shape genetic structure: insights from a model freshwater population along a land use gradient.

scientific article

Application of nd-SPME to determine freely dissolved concentrations in the presence of green algae and algae-water partition coefficients

scientific article published on 10 April 2010

Application of preparative capillary gas chromatography (pcGC), automated structure generation and mutagenicity prediction to improve effect-directed analysis of genotoxicants in a contaminated groundwater

scientific article

Application of the sea urchin embryo test in toxicity evaluation and effect directed analysis of wastewater treatment plant effluents

scientific article published on 11 June 2020

Aquatic occurrence of phytotoxins in small streams triggered by biogeography, vegetation growth stage, and precipitation

scientific article published in 2021

Assessing the genotoxic potential of freshwater sediments after extensive rain events – Lessons learned from a case study in an effluent-dominated river in Germany

Assessing the mixture effects in in-vitro bioassays of chemicals occurring in small agricultural streams during rain events

scientific article published on 05 June 2020

Assessment of a novel device for onsite integrative large-volume solid phase extraction of water samples to enable a comprehensive chemical and effect-based analysis

scientific article published on 3 January 2017

Author Correction: Pesticide pollution in freshwater paves the way for schistosomiasis transmission

scientific article published on 07 April 2020

Automated fractionation procedure for polycyclic aromatic compounds in sediment extracts on three coupled normal-phase high-performance liquid chromatography columns

scientific article

Automated strategies to identify compounds on the basis of GC/EI-MS and calculated properties

scientific article published on 12 January 2011

Bioanalytical equivalents and relative potencies for predicting the biological effects of mixtures

scientific article published on 20 October 2020

Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts - Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring

scientific article

Bioassay-Directed Identification of Organic Toxicants in River Sediment in the Industrial Region of Bitterfeld (Germany) A Contribution to Hazard Assessment

article

Bioavailability in effect-directed analysis of organic toxicants in sediments

Biological and chemical determination of dioxin-like compounds in sediments by means of a sediment triad approach in the catchment area of the river Neckar

scientific article published in October 2002

Body burden of pesticides and wastewater-derived pollutants on freshwater invertebrates: Method development and application in the Danube River

scientific article published on 8 April 2016

CONFIRMATION OF CAUSE–EFFECT RELATIONSHIPS USING EFFECT-DIRECTED ANALYSIS FOR COMPLEX ENVIRONMENTAL SAMPLES

scientific article published on 01 June 2005

Carbamazepine and its metabolites in wastewater: Analytical pitfalls and occurrence in Germany and Portugal

scientific article published on 19 March 2014

Characterization and risk assessment of seasonal and weather dynamics in organic pollutant mixtures from discharge of a separate sewer system

scientific article published on 3 February 2018

Characterizing field sediments from three European river basins with special emphasis on endocrine effects - A recommendation for Potamopyrgus antipodarum as test organism

scientific article published on 24 April 2010

Chemical activity and distribution of emerging pollutants: Insights from a multi-compartment analysis of a freshwater system.

scientific article

Chemical and ecotoxicological assessment of polycyclic aromatic hydrocarbon--contaminated sediments of the Niger Delta, Southern Nigeria

scientific article published in March 2005

Chemicals in the Environment (CITE)

scientific article published in 2010

ChlorophyllaFluorescence: A Tool for the Investigation of Toxic Effects in the Photosynthetic Apparatus

article

Computational material flow analysis for thousands of chemicals of emerging concern in European waters

scientific article published on 18 April 2020

Computer Tools for Structure Elucidation in Effect-Directed Analysis

Consensus Structure Elucidation Combining GC/EI-MS, Structure Generation, and Calculated Properties

scientific article published in 2012

Correction to Symbolic Aggregate Approximation Improves Gap Filling in High-Resolution Mass Spectrometry Data Processing

scientific article published in 2021

Corrigendum to “European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters” [Sci. Total Environ. 601–602 (2017) 1849–1868]

scientific article published on 05 May 2018

Current EU research activities on combined exposure to multiple chemicals

article

Decoding and Discrimination of Chemical Cues and Signals: Avoidance of Predation and Competition during Parental Care Behavior in Sympatric Poison Frogs

scientific article

Detecting a wide range of environmental contaminants in human blood samples—combining QuEChERS with LC-MS and GC-MS methods

scientific article published on 24 July 2015

Determination of 10 particle-associated multiclass polar and semi-polar pesticides from small streams using accelerated solvent extraction

scientific article published on 7 November 2007

Differential expression of CYP1A1 and CYP1A2 genes in H4IIE rat hepatoma cells exposed to TCDD and PAHs

scientific article

Downscaling procedures reduce chemical use in androgen receptor reporter gene assay

scientific article published on 16 July 2016

EDA-EMERGE: an FP7 initial training network to equip the next generation of young scientists with the skills to address the complexity of environmental contamination with emerging pollutants

scientific article published in 2013

Ecotoxicological Profiling of Transect River Elbe Sediments

article by Matthias Grote et al published December 2005 in CLEAN - Soil, Air, Water

Effect Directed Analysis and Toxicity Identification Evaluation

article

Effect directed analysis of riverine sediments--the usefulness of Potamopyrgus antipodarum for in vivo effect confirmation of endocrine disruption.

scientific article published on 20 October 2010

Effect-Directed Analysis of Progestogens and Glucocorticoids at Trace Concentrations in River Water

scientific article published on 30 November 2019

Effect-based assessment of toxicity removal during wastewater treatment

scientific article published on 7 September 2017

Effect-based methods are key. The European Collaborative Project SOLUTIONS recommends integrating effect-based methods for diagnosis and monitoring of water quality

scientific article published in 2019

Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive

scientific article published on 14 February 2018

Effect-directed analysis (EDA) of Danube River water sample receiving untreated municipal wastewater from Novi Sad, Serbia

scientific article published on 27 December 2017

Effect-directed analysis for estrogenic compounds in a fluvial sediment sample using transgenic cyp19a1b-GFP zebrafish embryos.

scientific article published on 19 May 2014

Effect-directed analysis of Ah receptor-mediated activities caused by PAHs in suspended particulate matter sampled in flood events

scientific article published on 24 April 2010

Effect-directed analysis of aryl hydrocarbon receptor agonists in sediments from the Three Gorges Reservoir, China

scientific article published on 18 September 2016

Effect-directed analysis of contaminated sediment from the wastewater canal in Pancevo industrial area, Serbia.

scientific article published on 19 September 2009

Effect-directed analysis of contaminated sediments with partition-based dosing using green algae cell multiplication inhibition

scientific article published in October 2009

Effect-directed analysis of key toxicants in European river basins a review.

scientific article published on January 2007

Effect-directed analysis of mutagens and ethoxyresorufin-o-deethylase inducers in aquatic sediments

scientific article published on October 2005

Effect-directed analysis of sediment-associated algal toxicants at selected hot spots in the river Elbe basin with a special focus on bioaccessibility

scientific article published on 19 February 2009

Effect-directed analysis supporting monitoring of aquatic environments--An in-depth overview

scientific article

Effect-directed analysis: a promising tool for the identification of organic toxicants in complex mixtures?

scientific article

Effect-directed fractionation and identification of cytochrome p4501A-inducing halogenated aromatic hydrocarbons in a contaminated sediment

scientific article published on December 2002

Effect-directed identification of oxygen and sulfur heterocycles as major polycyclic aromatic cytochrome P4501A-inducers in a contaminated sediment

scientific article published in July 2003

Effects-Directed Analysis of Sediments From Polluted Marine Sites in Norway

scientific article published on 01 January 2011

Effects-directed analysis (EDA) and toxicity identification evaluation (TIE): Complementary but different approaches for diagnosing causes of environmental toxicity

scientific article published on September 2013

Eine Weight-of-Evidence-Studie zur Bewertung der Sedimentbelastung und des Fischrückgangs in der Oberen Donau

article

Endocrine disrupting, mutagenic, and teratogenic effects of upper Danube River sediments using effect-directed analysis

scientific article

Endocrine disruption of water and sediment extracts in a non-radioactive dot blot/RNAse protection-assay using isolated hepatocytes of rainbow trout

scientific article published in November 2005

Establish data infrastructure to compile and exchange environmental screening data on a European scale

scientific article published on 30 September 2019

Estrogen receptor mediated activity in bankside groundwater, with flood suspended particulate matter and floodplain soil - an approach combining tracer substance, bioassay and target analysis

article

Estrogenic activity of surface waters using zebrafish- and human-based in vitro assays: The Danube as a case-study

scientific article published on 01 May 2020

European River Basins at Risk

scientific article published on 01 January 2009

European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters

scientific article published on 14 June 2017

Evidence for antifouling biocides as one of the limiting factors for the recovery of macrophyte communities in lakes of Schleswig-Holstein

scientific article published in 2021

Extending analysis of environmental pollutants in human urine towards screening for suspected compounds

scientific article published on 23 March 2015

Fractionation of technical p-nonylphenol with preparative capillary gas chromatography

scientific article published on 02 August 2007

From the exposome to mechanistic understanding of chemical-induced adverse effects

scientific article

Future water quality monitoring--adapting tools to deal with mixtures of pollutants in water resource management

scientific article published on 31 January 2015

HPLC/APCI-FTICR-MS as a tool for identification of partial polar mutagenic compounds in effect-directed analysis

scientific article published on 12 February 2010

Heterocyclic aromatic hydrocarbons show estrogenic activity upon metabolization in a recombinant transactivation assay

scientific article published on 29 April 2014

High-resolution mass spectrometry to complement monitoring and track emerging chemicals and pollution trends in European water resources

scientific article published on 30 September 2019

How to confirm identified toxicants in effect-directed analysis

scientific article

Identification and evaluation of cyp1a transcript expression in fish as molecular biomarker for petroleum contamination in tropical fresh water ecosystems.

scientific article

Identification and quantitative confirmation of dinitropyrenes and 3-nitrobenzanthrone as major mutagens in contaminated sediments

scientific article published on 13 February 2012

Identification of Mutagenic Aromatic Amines in River Samples with Industrial Wastewater Impact

scientific article published on 7 April 2017

Identification of Unknown Antiandrogenic Compounds in Surface Waters by Effect-Directed Analysis (EDA) Using a Parallel Fractionation Approach

scientific article

Identification of a phytotoxic photo-transformation product of diclofenac using effect-directed analysis

scientific article published on 21 January 2010

Identification of novel micropollutants in wastewater by a combination of suspect and nontarget screening

scientific article published on 6 September 2013

Identification of toxic products of anthracene photomodification in simulated sunlight

scientific article published in October 2003

Identification of toxicants from marine sediment using effect-directed analysis

scientific article

Identifizierung toxischer Verbindungen in Sedimenten: Ansätze zur Integration von Wirkung und Bioverfügbarkeit

scientific article published in 2009

Impact of contaminants bound to suspended particulate matter in the context of flood events

article by Jan Wölz et al published 25 June 2010 in Journal of Soils and Sediments

Impact of untreated wastewater on a major European river evaluated with a combination of in vitro bioassays and chemical analysis

scientific article published on 21 November 2016

Improving the Screening Analysis of Pesticide Metabolites in Human Biomonitoring by Combining High-Throughput <i>In Vitro</i> Incubation and Automated LC–HRMS Data Processing

scientific article published on 23 June 2021

In silico deconjugation of glucuronide conjugates enhances tandem mass spectra library annotation of human samples

scientific article published on 26 January 2022

Induction of aryl hydrocarbon receptor-mediated and estrogen receptor-mediated activities, and modulation of cell proliferation by dinaphthofurans.

scientific article published on September 2004

Integrated analytical and computer tools for structure elucidation in effect-directed analysis

article

Integrated biological-chemical approach for the isolation and selection of polyaromatic mutagens in surface waters

scientific article published on 22 September 2013

Integrated zebrafish-based tests as an investigation strategy for water quality assessment

scientific article published on 28 November 2018

Investigation on soil contamination at recently inundated and non-inundated sites

Is chemosensitisation by environmental pollutants ecotoxicologically relevant?

scientific article published on 31 July 2015

Isolation and characterization of eleven novel microsatellite markers for fine-scale population genetic analyses of Gammarus pulex (Crustacea: Amphipoda)

scientific article published on 24 September 2019

LIGHT AS A CONFOUNDING FACTOR FOR TOXICITY ASSESSMENT OF COMPLEX CONTAMINATED SEDIMENTS

scientific article published on 01 December 2005

Large volume TENAX® extraction of the bioaccessible fraction of sediment-associated organic compounds for a subsequent effect-directed analysis

article

Let us empower the WFD to prevent risks of chemical pollution in European rivers and lakes

scientific article published on 7 August 2019

Linear Solvation Energy Relationships as classifiers in non-target analysis—A capillary liquid chromatography approach

article

Linear solvation energy relationships as classifier in non-target analysis--an approach for isocratic liquid chromatography

scientific article published on 16 November 2013

Linear solvation energy relationships as classifiers in non-target analysis – A gas chromatographic approach

Linking in Vitro Effects and Detected Organic Micropollutants in Surface Water Using Mixture-Toxicity Modeling

scientific article published on 30 October 2015

Linking mutagenic activity to micropollutant concentrations in wastewater samples by partial least square regression and subsequent identification of variables

scientific article

Longitudinal profile of the genotoxic potential of the River Danube on erythrocytes of wild common bleak (Alburnus alburnus) assessed using the comet and micronucleus assay

scientific article

Looking back - Looking forward: A novel multi-time slice weight-of-evidence approach for defining reference conditions to assess the impact of human activities on lake systems

article

MODELKEY

article published in 2010

MODELKEY. Models for assessing and forecasting the impact of environmental key pollutants on freshwater and marine ecosystems and biodiversity

scientific article

Matching structures to mass spectra using fragmentation patterns: are the results as good as they look?

scientific article published in May 2009

Measuring the internal concentration of volatile organic compounds in small organisms using micro-QuEChERS coupled to LVI-GC-MS/MS.

scientific article

Metabolic transformation as a diagnostic tool for the selection of candidate promutagens in effect-directed analysis

scientific article published on 01 January 2015

Microbial reporter gene assay as a diagnostic and early warning tool for the detection and characterization of toxic pollution in surface waters

scientific article

Miniaturization of the microsuspension Salmonella/microsome assay in agar microplates

scientific article published on 18 April 2018

Mixtures of organic micropollutants exacerbated in vitro neurotoxicity of prymnesins and contributed to aquatic toxicity during a toxic algal bloom

scientific article published on 6 September 2024

Morphological and behavioral alterations in zebrafish larvae after exposure to contaminated river sediments collected in different weather conditions

scientific article published in 2022

Multicriteria approach to select polyaromatic river mutagen candidates.

scientific article

Mutagenicity in Surface Waters: Synergistic Effects of Carboline Alkaloids and Aromatic Amines

scientific article published on 3 January 2017

Non-targeted mercapturic acid screening in urine using LC-MS/MS with matrix effect compensation by postcolumn infusion of internal standard (PCI-IS)

scientific article published on 30 October 2019

Nontargeted detection and identification of (aromatic) amines in environmental samples based on diagnostic derivatization and LC-high resolution mass spectrometry

scientific article

Novel metabolites in cyanobacterium Cylindrospermopsis raciborskii with potencies to inhibit gap junctional intercellular communication.

scientific article published on 16 September 2013

Occurrence and risk assessment of organic micropollutants in freshwater systems within the Lake Victoria South Basin, Kenya

scientific article published on 22 January 2020

On the Mode of Action ofN-Phenyl-2-naphthylamine in Plants

article

Optimisation of trapping parameters in preparative capillary gas chromatography for the application in effect-directed analysis

scientific article published on 25 November 2009

Optimization of LC-Orbitrap-HRMS acquisition and MZmine 2 data processing for nontarget screening of environmental samples using design of experiments

scientific article

Organic chemicals jeopardize the health of freshwater ecosystems on the continental scale

scientific article

Partitioning-based dosing: an approach to include bioavailability in the effect-directed analysis of contaminated sediment samples.

scientific article published in May 2009

Passive dosing: An approach to control mutagen exposure in the Ames fluctuation test

scientific article published on 26 January 2011

People, pollution and pathogens - Global change impacts in mountain freshwater ecosystems

scientific article

Performance of combined fragmentation and retention prediction for the identification of organic micropollutants by LC-HRMS.

scientific article published on 30 January 2018

Pesticide Body Burden of the Crustacean Gammarus pulex as a Measure of Toxic Pressure in Agricultural Streams

scientific article published on 06 July 2018

Pesticide pollution in freshwater paves the way for schistosomiasis transmission

scientific article published on 27 February 2020

Pesticides are the dominant stressors for vulnerable insects in lowland streams

scientific article published in August 2021

Physiological sensitivity of freshwater macroinvertebrates to heavy metals

scientific article published on 22 June 2012

Polar compounds dominate in vitro effects of sediment extracts

scientific article

Pollution-Induced Community Tolerance To Diagnose Hazardous Chemicals in Multiple Contaminated Aquatic Systems

scientific article

Polychlorinated naphthalenes and other dioxin-like compounds in Elbe River sediments

scientific article published on March 2008

Polychlorinated naphthalenes in sediments from the industrial region of Bitterfeld

scientific article published in January 2003

Polycyclic aromatic hydrocarbon (PAH) contamination of surface sediments and oysters from the inter-tidal areas of Dar es Salaam, Tanzania

scientific article

Predicting the bioaccumulation of polyaromatic hydrocarbons and polychlorinated biphenyls in benthic animals in sediments

scientific article published on 30 April 2016

Prediction of gas chromatographic retention indices as classifier in non-target analysis of environmental samples

scientific article published on 19 February 2013

Project house water: a novel interdisciplinary framework to assess the environmental and socioeconomic consequences of flood-related impacts

scientific article

Read-Across Prediction of the Acute Toxicity of Organic Compounds toward the Water Flea Daphnia magna

scientific article published on 15 January 2013

Remobilization of pollutants during extreme flood events poses severe risks to human and environmental health

scientific article

River Basin Risk Assessment Linked to Monitoring and Management

Screening hundreds of emerging organic pollutants (EOPs) in surface water from the Yangtze River Delta (YRD): Occurrence, distribution, ecological risk

scientific article published on 04 June 2018

Screening of Pesticide and Biocide Patterns As Risk Drivers in Sediments of Major European River Mouths: Ubiquitous or River Basin-Specific Contamination?

scientific article published on 21 January 2018

Solid-phase extraction as sample preparation of water samples for cell-based and other in vitro bioassays

scientific article published on 01 March 2018

Spatial and temporal variations in anti-androgenic activity and environmental risk in a small river

scientific article published in 2022

Statement on advancing the assessment of chemical mixtures and their risks for human health and the environment

scientific article published on 06 November 2019

Strengthen the European collaborative environmental research to meet European policy goals for achieving a sustainable, non-toxic environment

scientific article published on 30 September 2019

Symbolic Aggregate Approximation Improves Gap Filling in High-Resolution Mass Spectrometry Data Processing

scientific article published on 27 July 2020

The Challenge: Prioritization of emerging pollutants

scientific article published on 01 October 2015

The EU chemicals strategy for sustainability: an opportunity to develop new approaches for hazard and risk assessment

scientific article published in 2022

The European Water Framework Directive beyond 2010: let actions speak louder than words.

scientific article published on 14 October 2010

The European technical report on aquatic effect-based monitoring tools under the water framework directive

scientific article published in 2015

The NORMAN Network and its activities on emerging environmental substances with a focus on effect-directed analysis of complex environmental contamination

article

The NORMAN Suspect List Exchange (NORMAN-SLE): facilitating European and worldwide collaboration on suspect screening in high resolution mass spectrometry

scientific article published on 21 October 2022

The SOLUTIONS project: challenges and responses for present and future emerging pollutants in land and water resources management

scientific article

The impact of chemosensitisation on bioaccumulation and sediment toxicity

scientific article

The impact of extraction methodologies on the toxicity of sediments in the zebrafish (Danio rerio) embryo test

article

The use of MS classifiers and structure generation to assist in the identification of unknowns in effect-directed analysis

scientific article published on 4 April 2008

The value of zebrafish as an integrative model in effect-directed analysis - a review

scientific article published in 2015

Toward a holistic and risk-based management of European river basins

scientific article published on January 2009

Toward an integrated assessment of the ecological and chemical status of European river basins

scientific article

Towards a holistic and solution-oriented monitoring of chemical status of European water bodies: how to support the EU strategy for a non-toxic environment?

article

Towards the review of the European Union Water Framework Directive: Recommendations for more efficient assessment and management of chemical contamination in European surface water resources

scientific article published on 27 October 2016

Tox-Box: securing drops of life - an enhanced health-related approach for risk assessment of drinking water in Germany

article

Toxicity assessment of sediments from three European river basins using a sediment contact test battery

scientific article published on 15 September 2010

Toxicity testing of highly volatile chemicals with green algae

article

Triclosan--the forgotten priority substance?

scientific article published on 11 August 2011

Unraveling longitudinal pollution patterns of organic micropollutants in a river by non-target screening and cluster analysis

scientific article published on 06 April 2020

Use of factorial design for the multivariate optimization of polypropylene membranes for the cleanup of environmental samples using the accelerated membrane-assisted cleanup approach

scientific article published on 3 January 2012

Von der Wirkung zur Substanz: Wirkungsbezogene Analytik als neue Untersuchungsstrategie in der Lebensmittelkontrolle

Water quality indices across Europe--a comparison of the good ecological status of five river basins

scientific article published on 30 July 2007

Wirkungsorientierte Analytik komplexer Mischungen Erfahrungen aus der Umwelt- und Ökotoxikologie für die Lebensmitteluntersuchung

Zinc and cadmium accumulation in single zebrafish (Danio rerio) embryos — A total reflection X-ray fluorescence spectrometry application

article

Über die Notwendigkeit der wirkungsorientierten Analytik in einer umfassenden Wasserforschung

scientific article published in 2009

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