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List of works by Paul Young

A Binational Multicenter Pilot Feasibility Randomized Controlled Trial of Early Goal-Directed Mobilization in the ICU.

scientific article published on 10 March 2016

A Pilot, Double-Blind, Randomized, Controlled Trial of High-Dose Intravenous Vitamin C for Vasoplegia After Cardiac Surgery

scientific article published on 24 August 2019

A case series of critically ill patients with anti- N-methyl-D-aspartate receptor encephalitis

scientific article published on 01 March 2013

A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol

scientific article published on 01 September 2018

A comparison of therapeutic hypothermia and strict therapeutic normothermia after cardiac arrest

scientific article published on 24 June 2016

A multicentre audit of temperature patterns after traumatic brain injury

scientific article published on June 2015

A pilot study investigating the effects of remote ischemic preconditioning in high-risk cardiac surgery using a randomised controlled double-blind protocol

scientific article published on 10 March 2012

A protocol for the 0.9% saline versus Plasma-Lyte 148 for intensive care fluid therapy (SPLIT) study

scientific article published on 01 December 2014

A randomized controlled feasibility trial of paracetamol during febrile neutropenia in hemato-oncology patients

scientific article published on 18 January 2019

A retrospective cohort study of the effect of medical emergency teams on documentation of advance care directives

scientific article published on September 1, 2011

A systematic review and meta-analysis of the cardioprotective effects of remote ischaemic preconditioning in open cardiac surgery.

scientific article published in October 2012

A systematic review of measurements of physical function in critically ill adults.

scientific article

A two centre observational study of simultaneous pulse oximetry and arterial oxygen saturation recordings in intensive care unit patients

scientific article published on 01 May 2018

Acetaminophen for Fever in Critically Ill Patients with Suspected Infection

scientific article published on 5 October 2015

Acetaminophen for Fever in Critically Ill Patients with Suspected Infection

scientific article published on 01 March 2016

Acetaminophen to treat fever in intensive care unit patients with likely infection: a response from the author of the HEAT trial

scientific article published on July 2016

Acute Kidney Injury With Buffered Crystalloids vs Saline Among ICU Patients—Reply

scientific article published in The Journal of the American Medical Association

Admitting elderly patients to ICU: is it just about survival?

Angiotensin I and angiotensin II concentrations and their ratio in catecholamine-resistant vasodilatory shock

scientific article published on 06 February 2020

Angiotensin II for the Treatment of Vasodilatory Shock

scientific article published on 21 May 2017

Arterial carbon dioxide tension and outcome in patients admitted to the intensive care unit after cardiac arrest

scientific article published on 27 February 2013

Arterial oxygen tension and mortality in mechanically ventilated patients

Association between early peak temperature and mortality in neutropenic sepsis

scientific article published on 18 December 2014

Balanced Crystalloids or 0.9% Saline in Sepsis. Beyond Reasonable Doubt?

scientific article published on 01 December 2019

Can social media bridge the gap between research and practice?

scientific article published in December 2013

Cardiac arrest complicating neostigmine use for bowel opening in a critically ill patient

scientific article published on 01 September 2011

Changes in Temperature Management of Cardiac Arrest Patients Following Publication of the Target Temperature Management Trial*

scientific article published on 01 November 2018

Characteristics and Outcomes of Critically Ill Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Australia and New Zealand

scientific article published on 05 March 2020

Characteristics and Outcomes of Critically Ill Trauma Patients in Australia and New Zealand (2005-2017)

scientific article published on 27 February 2020

Characteristics and Outcomes of Patients with Acute Liver Failure Admitted to Australian and New Zealand Intensive Care Units

article

Characteristics, incidence, and outcome of patients admitted to the intensive care unit with myasthenia gravis

scientific article published on 7 January 2018

Choice of Fluid Therapy and Bleeding Risk After Cardiac Surgery

scientific article published on 18 December 2015

Conservative Oxygen Therapy during Mechanical Ventilation in the ICU

scientific article published on 14 October 2019

Conservative oxygen therapy for mechanically ventilated adults with sepsis: a post hoc analysis of data from the intensive care unit randomized trial comparing two approaches to oxygen therapy (ICU-ROX)

scientific article published on 20 November 2019

Conservative oxygen therapy in mechanically ventilated patients.

scientific article published in September 2014

Conservative versus Liberal Oxygenation Targets for Mechanically Ventilated Patients. A Pilot Multicenter Randomized Controlled Trial

scientific article published on 3 September 2015

Conservative versus liberal oxygenation targets for mechanically ventilated patients: pilot multicentre randomised trial.

scientific article published in October 2015

Could stress ulcer prophylaxis increase mortality in high-acuity patients?

scientific article published on 19 February 2020

Critical care statistical analysis plans. In reply

Crystalloid fluid therapy

scientific article

Crystalloid fluid therapy: is the balance tipping towards balanced solutions?

scientific article published on 11 November 2014

Delivery of titrated oxygen via a self-inflating resuscitation bag.

scientific article published on 3 September 2012

Development and Validation of a Score to Identify Cardiac Surgery Patients at High Risk of Prolonged Mechanical Ventilation

article

Early dysglycemia and mortality in traumatic brain injury and subarachnoid hemorrhage

scientific article published on 07 February 2019

Early mobilization and recovery in mechanically ventilated patients in the ICU: a bi-national, multi-centre, prospective cohort study

scientific article

Early peak temperature and mortality in critically ill patients with or without infection

scientific article published on 31 January 2012

Early temperature and mortality in critically ill patients with acute neurological diseases: trauma and stroke differ from infection

scientific article published on 3 February 2015

Effect of 0.9% Saline or Plasma-Lyte 148 as Crystalloid Fluid Therapy in the Intensive Care Unit on Blood Product Use and Postoperative Bleeding After Cardiac Surgery

scientific article published on 15 April 2017

Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial

scientific article published on 15 March 2016

Effect of Stress Ulcer Prophylaxis With Proton Pump Inhibitors vs Histamine-2 Receptor Blockers on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation: The PEPTIC Randomized Clinical Trial

scientific article published on 17 January 2020

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial

scientific article published on 17 January 2020

Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial

scientific article published on 07 October 2015

Effect of saline 0.9% or Plasma-Lyte 148 therapy on feeding intolerance in patients receiving nasogastric enteral nutrition

scientific article published in September 2016

Effect sizes in ongoing randomized controlled critical care trials

scientific article published on 5 June 2017

Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults

scientific article

Feasibility and inter-rater reliability of the ICU Mobility Scale

scientific article published on 19 November 2013

Fever and antipyresis in infection ⬇️

scientific article published on October 17, 2011

Fever control

scientific article

Fever control in critically ill adults. An individual patient data meta-analysis of randomised controlled trials

scientific article published on 11 February 2019

Fever in sepsis: is it cool to be hot?

scientific article

Fever management in intensive care patients with infections

scientific article published on 18 March 2014

Fluid administration, vasopressor use and patient outcomes in a group of high-risk cardiac surgical patients receiving postoperative goal-directed haemodynamic therapy: a pilot study.

scientific article published on September 2015

Fluid management in acute kidney injury

scientific article published on 03 May 2017

HyperOxic Therapy OR NormOxic Therapy after out-of-hospital cardiac arrest (HOT OR NOT): a randomised controlled feasibility trial.

scientific article

Improved survival in critically ill patients: are large RCTs more useful than personalized medicine? Yes.

scientific article published on 12 September 2016

Intensive care triage in Australia and New Zealand.

scientific article published on 11 June 2010

Intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX): results of the pilot phase

Is sepsis treatment heating up?

scientific article published on 01 June 2019

Learning Healthcare Systems Will Protect Patients from Unscientific Practice Variation

scientific article published on 28 November 2017

Mean arterial pressure and mortality in patients with distributive shock: a retrospective analysis of the MIMIC-III database

scientific article published on 08 November 2018

Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis.

scientific article

O2, do we know what to do?

scientific article published on 01 December 2019

Outcomes Six Months after Delivering 100% or 70% of Enteral Calorie Requirements during Critical Illness (TARGET). A Randomized Controlled Trial

scientific article published on 01 April 2020

Overview of the study protocols and statistical analysis plan for the Saline versus Plasma-Lyte 148 for Intravenous Fluid Therapy (SPLIT) research program

scientific article published on March 2015

Oxygen therapy in acute resuscitation

scientific article published on 01 December 2018

Oxygen: a new look at an old therapy

Practice patterns and perceptions of Australian and New Zealand anaesthetists towards perioperative oxygen therapy

scientific article published on 24 May 2019

Protocol and statistical analysis plan for the Randomised Evaluation of Active Control of Temperature versus Ordinary Temperature Management (REACTOR) trial

Protocol summary and statistical analysis plan for the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX).

scientific article published in March 2018

Randomised evaluation of active control of temperature versus ordinary temperature management (REACTOR) trial

scientific article published on 01 October 2019

Registrar sleep patterns and supervision during two different rosters in a tertiary Australasian intensive care unit.

scientific article published in March 2012

Remote ischaemic preconditioning does not alter perioperative cytokine production in high-risk cardiac surgery

scientific article published on 13 August 2012

Renal nerve and alpha 2-adrenergic action during acute volume expansion in the anaesthetized rat.

scientific article published in August 1999

Renoprotection by remote ischemic conditioning during elective coronary revascularization: A systematic review and meta-analysis of randomized controlled trials

scientific article

Reply to Letter: Could one degree in temperature change the world? Maybe for targeted temperature management!

scientific article published on 02 August 2016

Reply to: Too Many Calories for All?

scientific article published on 09 June 2020

Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

scientific article published on 12 November 2017

Saline Is the Solution for Crystalloid Resuscitation.

scientific article

Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery

article

Statistical analysis plan for the HEAT trial: a multicentre randomised placebo-controlled trial of intravenous paracetamol in intensive care unit patients with fever and infection

scientific article

Systematic review and meta-analysis of the effects of antipyretic medications on mortality in Streptococcus pneumoniae infections

scientific article

Targeted hypothermia versus targeted Normothermia after out-of-hospital cardiac arrest (TTM2): A randomized clinical trial-Rationale and design

scientific article published on 26 June 2019

The "sweet spot" for physiological targets in critically ill patients

scientific article published on 01 December 2012

The Fragility Index in Multicenter Randomized Controlled Critical Care Trials

scientific article published on 9 March 2016

The HEAT trial: a protocol for a multicentre randomised placebo-controlled trial of IV paracetamol in ICU patients with fever and infection

scientific article published in December 2012

The ICU Mobility Scale Has Construct and Predictive Validity and Is Responsive. A Multicenter Observational Study

scientific article

The Plasma-Lyte 148 v Saline (PLUS) study protocol: a multicentre, randomised controlled trial of the effect of intensive care fluid therapy on mortality

scientific article published in September 2017

The Plasma-Lyte 148 versus Saline (PLUS) study protocol amendment

scientific article published on 01 December 2019

The Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia (REMAP-CAP) Study: Rationale and Design

scientific article published on 08 April 2020

The Risk of Hyperoxemia in ICU Patients. Much Ado About O2

scientific article published on 01 December 2019

The association between SpO2 values and mortality--interpret with caution

scientific article

The association between early arterial oxygenation and mortality in ventilated patients with acute ischaemic stroke.

scientific article published in March 2012

The authors reply

The effect of hyperoxia following cardiac arrest - A systematic review and meta-analysis of animal trials.

scientific article published on 05 January 2012

The impact of oxygen and carbon dioxide management on outcome after cardiac arrest

scientific article published on June 2014

The implications of the PEPTIC trial for clinical practice

scientific article published on 01 March 2020

Timing of Initiation of Renal Replacement Therapy in Critically Ill Patients With Acute Kidney Injury

scientific article published in September 2016

Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury

scientific article published on 01 July 2020

Trauma-related admissions to intensive care units in Australia: the influence of Indigenous status on outcomes

scientific article published on 07 December 2018

Validation of a classification system for causes of death in critical care: an assessment of inter-rater reliability

scientific article published in March 2016

Vasopressin in septic shock: what we know and where to next?

scientific article published on 13 May 2019

Vitamin C therapy for patients with sepsis or septic shock: a protocol for a systematic review and a network meta-analysis

scientific article published on 12 November 2019

Vitamin C, Hydrocortisone and Thiamine in Patients with Septic Shock (VITAMINS) trial: study protocol and statistical analysis plan

scientific article published on 01 June 2019

What should we target after TARGET?

scientific article published on 01 December 2018

What's new on balanced crystalloid solutions?

scientific article published on 17 August 2016

When less is more in the active management of elevated body temperature of ICU patients

scientific article published on 19 June 2019

Why don't multicenter randomized controlled trials (RCT) confirm the positive findings of single center RCTs in acute care? (Zeno's Paradox of the Tortoise and Achilles revisited)

scientific article published on 30 October 2018

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