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List of works by Mark P Little

A comparison of the degree of curvature in the cancer incidence dose-response in Japanese atomic bomb survivors with that in chromosome aberrations measured in vitro

scientific article published on 01 October 2000

A comparison of the risk of stillbirth associated with paternal pre-conception irradiation in the Sellafield workforce with that of stillbirth and untoward pregnancy outcome among Japanese atomic bomb survivors.

scientific article

A dose of the bomb

scientific article published in Nature

A model of cardiovascular disease giving a plausible mechanism for the effect of fractionated low-dose ionizing radiation exposure

scientific article

A multi-compartment cell repopulation model allowing for inter-compartmental migration following radiation exposure, applied to leukaemia

scientific article published in October 2006

A reanalysis of curvature in the dose response for cancer and modifications by age at exposure following radiation therapy for benign disease

scientific article

A record-based case-control study of natural background radiation and the incidence of childhood leukaemia and other cancers in Great Britain during 1980-2006.

scientific article published on 05 June 2012

A review of non-cancer effects, especially circulatory and ocular diseases

scientific article

A review of studies of childhood cancer and natural background radiation

scientific article published on 04 January 2021

A stochastic carcinogenesis model incorporating genomic instability fitted to colon cancer data.

scientific article

A stochastic carcinogenesis model incorporating multiple types of genomic instability fitted to colon cancer data

scientific article

Absence of evidence for differences in the dose-response for cancer and non-cancer endpoints by acute injury status in the Japanese atomic-bomb survivors

scientific article published on 01 November 2002

Ambient temperature and risk of first primary basal cell carcinoma: a nationwide United States cohort study

journal article published in 2015

Analysis of dose response for circulatory disease after radiotherapy for benign disease

scientific article

Analysis of lung tumour risk in radon-exposed rats: an intercomparison of multi-step modelling

scientific article published in December 2000

Analysis of retinoblastoma age incidence data using a fully stochastic cancer model.

scientific article

Analysis of thyroid malignant pathologic findings identified during 3 rounds of screening (1997-2008) of a cohort of children and adolescents from belarus exposed to radioiodines after the Chernobyl accident.

scientific article published on 28 October 2014

Are cancer risks associated with exposures to ionising radiation from internal emitters greater than those in the Japanese A-bomb survivors?

scientific article published on 17 July 2007

Are two mutations sufficient to cause cancer? Some generalizations of the two-mutation model of carcinogenesis of Moolgavkar, Venzon, and Knudson, and of the multistage model of Armitage and Doll

scientific article

Association between microfilarial load and excess mortality in onchocerciasis: an epidemiological study

scientific article published in May 2004

Association of chromosome translocation rate with low dose occupational radiation exposures in U.S. radiologic technologists

scientific article

Associations between pre-pregnancy obesity and asthma symptoms in adolescents

scientific article

Belarusian in utero cohort: A new opportunity to evaluate the health effects of prenatal and early-life exposure to ionising radiation

scientific article published on 26 November 2019

Breast cancer incidence in a cohort of U.S. flight attendants

journal article published in 2015

Breast cancer risk after radiotherapy for heritable and non-heritable retinoblastoma: a US-UK study

scientific article

Cancer after exposure to radiation in the course of treatment for benign and malignant disease.

scientific article

Cancer and circulatory disease risks in US radiologic technologists associated with performing procedures involving radionuclides.

journal article published in 2015

Cancer in the offspring of radiation workers: a record linkage study.

scientific article

Cancer models, genomic instability and somatic cellular Darwinian evolution

scientific article

Cancer predisposition, radiosensitivity and the risk of radiation-induced cancers. III. Effects of incomplete penetrance and dose-dependent radiosensitivity on cancer risks in populations

scientific article published on 01 March 1997

Cancer predisposition, radiosensitivity and the risk of radiation-induced cancers. IV. Prediction of risks in relatives of cancer-predisposed individuals

scientific article published on 01 May 1998

Change in salt intake affects blood pressure of chimpanzees: implications for human populations

scientific article

Childhood cancer after low-level intrauterine exposure to radiation

scientific article published on 01 September 2002

Circulatory disease mortality in the Massachusetts tuberculosis fluoroscopy cohort study

scientific article published on 9 August 2015

Comment on "Use of A-bomb survivor studies as a basis for nuclear worker compensation" ⬇️

scientific article published on May 1, 2003

Comments on "Are the risks from tritium exposures being underestimated?".

scientific article published in September 2009

Comments on "Impact of tritium around EDF nuclear power plants"

scientific article published on 01 September 2009

Comments on 'Estimation of X ray overexposure in a childhood leukaemia cluster by means of chromosome aberration analysis'.

scientific article published in January 2003

Comments on the Article "Studies of the Mortality of Atomic Bomb Survivors. Report 12, Part I. Cancer: 1950-1990" by D. A. Pierce, Y. Shimizu, D. L. Preston, M. Vaeth and K. Mabuchi (Radiat. Res. 146, 1-27, 1996)

scientific article published on October 1, 1997

Comments on the paper: Microsatellite instability in acute myelocytic leukaemia developed from A-bomb survivors

scientific article published on 01 May 2002

Comments: The non-cancer mortality experience of male workers at British Nuclear Fuels plc, 1946-2005.

scientific article published on 9 July 2008

Comparison of breast cancer incidence in the Massachusetts tuberculosis fluoroscopy cohort and in the Japanese atomic bomb survivors

scientific article published on 01 February 1999

Comparison of the risks of cancer incidence and mortality following radiation therapy for benign and malignant disease with the cancer risks observed in the Japanese A-bomb survivors

scientific article published on 01 April 2001

Comparisons of lung tumour mortality risk in the Japanese A-bomb survivors and in the Colorado Plateau uranium miners: support for the ICRP lung model

scientific article published on 01 March 2002

Corrections to the paper "Fitting the Armitage-Doll model to radiation-exposed cohorts and implications for population cancer risks

scientific article published on 01 January 1994

Cumulative solar ultraviolet radiation exposure and basal cell carcinoma of the skin in a nationwide US cohort using satellite and ground-based measures

scientific article published on 27 December 2019

Curvature in the cancer mortality dose response in Japanese atomic bomb survivors: absence of evidence of threshold

article

Curvilinearity in the dose-response curve for cancer in Japanese atomic bomb survivors ⬇️

scientific article published on December 1, 1997

Database of normalised computed tomography dose index for retrospective CT dosimetry

scientific article published on 14 April 2014

Density-dependent mortality of the human host in onchocerciasis: Relationships between microfilarial load and excess mortality

scientific article

Derivation of low-dose extrapolation factors from analysis of curvature in the cancer incidence dose response in Japanese atomic bomb survivors.

scientific article published in July 2000

Describing time and age variations in the risk of radiation-induced solid tumour incidence in the Japanese atomic bomb survivors using generalized relative and absolute risk models

scientific article published on 01 January 1999

ETV6-NTRK3 is a common chromosomal rearrangement in radiation-associated thyroid cancer

scientific article published on 10 December 2013

Early growth and adult respiratory function in men and women followed from the fetal period to adulthood

scientific article

Editorial. Non-DNA targeted effects

scientific article published on 25 January 2010

Estimates of neutron relative biological effectiveness derived from the Japanese atomic bomb survivors ⬇️

scientific article published on 01 December 1997

Evidence for curvilinearity in the cancer incidence dose-response in the Japanese atomic bomb survivors

article

Evidence relevant to untargeted and transgenerational effects in the offspring of irradiated parents ⬇️

scientific article published on 04 May 2013

Exposure to radiation and higher risk of circulatory disease

scientific article published on 14 January 2010

Factors affecting recognition of cancer risks of nuclear workers

scientific article published on 01 July 1996

Factors associated with serum thyroglobulin in a Ukrainian cohort exposed to iodine-131 from the accident at the Chernobyl Nuclear Plant

scientific article published on 12 May 2017

Female estrogen-related factors and incidence of basal cell carcinoma in a nationwide US cohort

journal article published in 2015

Field Study of the Possible Effect of Parental Irradiation on the Germline of Children Born to Cleanup Workers and Evacuees of the Chornobyl Accident

scientific article published on 02 July 2020

Fitting the Armitage-Doll model to radiation-exposed cohorts and implications for population cancer risks

scientific article published on November 1, 1992

Flexible dose-response models for Japanese atomic bomb survivor data: Bayesian estimation and prediction of cancer risk.

scientific article published on 25 November 2004

Funding crisis at the Radiation Effects Research Foundation

scientific article published on 01 September 2004

Germline minisatellite mutations in the offspring of irradiated parents

scientific article

Hemoglobin concentration in pregnancy and perinatal mortality: a London-based cohort study

scientific article published in July 2005

Heterogeneity of variation of relative risk by age at exposure in the Japanese atomic bomb survivors.

scientific article published on 27 May 2009

Histopathological features of papillary thyroid carcinomas detected during four screening examinations of a Ukrainian-American cohort

scientific article

How is the risk of radiation-induced cancer influenced by background risk factors? Invited commentary on "a method for determining weights for excess relative risk and excess absolute risk when applied in the calculation of lifetime risk of cancer f

scientific article published on 20 November 2012

Human infection patterns and heterogeneous exposure in river blindness.

scientific article

Impact of Uncertainties in Exposure Assessment on Thyroid Cancer Risk among Persons in Belarus Exposed as Children or Adolescents Due to the Chernobyl Accident

scientific article published on 14 October 2015

Impact of uncertainties in exposure assessment on estimates of thyroid cancer risk among Ukrainian children and adolescents exposed from the Chernobyl accident

scientific article published on 29 January 2014

Improving Assessment of Lifetime Solar Ultraviolet Radiation Exposure in Epidemiologic Studies: Comparison of Ultraviolet Exposure Assessment Methods in a Nationwide U.S. Occupational Cohort

scientific article published on 06 August 2018

Incidence and mortality risks for circulatory diseases in US radiologic technologists who worked with fluoroscopically guided interventional procedures, 1994-2008.

journal article published in 2016

Incidence of blindness during the Onchocerciasis control programme in western Africa, 1971-2002.

scientific article published on 27 April 2004

Individual, environmental, and meteorological predictors of daily personal ultraviolet radiation exposure measurements in a United States cohort study

scientific article

Inflammatory disease and C-reactive protein in relation to therapeutic ionising radiation exposure in the US Radiologic Technologists

scientific article published on 20 March 2019

Investigation of the Relationship Between Radiation Dose and Gene Mutations and Fusions in Post-Chernobyl Thyroid Cancer

scientific article published on 18 November 2017

Ionising radiation in the workplace

scientific article published on 20 October 2015

Lack of transgenerational effects of ionizing radiation exposure from the Chernobyl accident

scientific article published in 2021

Leukaemia following childhood radiation exposure in the Japanese atomic bomb survivors and in medically exposed groups

scientific article published on 20 October 2008

Low-dose ionising radiation and cardiovascular diseases--Strategies for molecular epidemiological studies in Europe

scientific article published on 03 April 2015

Low-dose radiation exposure and atherosclerosis in ApoE⁻/⁻ mice.

scientific article published on 04 March 2011

Maternal blood pressure in pregnancy, birth weight, and perinatal mortality in first births: prospective study

scientific article

Mathematical models of tissue stem and transit target cell divisions and the risk of radiation- or smoking-associated cancer

scientific article

Mobile phone use and glioma risk: comparison of epidemiological study results with incidence trends in the United States

scientific article

Modelling lung tumour risk in radon-exposed uranium miners using generalizations of the two-mutation model of Moolgavkar, Venzon and Knudson

article

New models for evaluation of radiation-induced lifetime cancer risk and its uncertainty employed in the UNSCEAR 2006 report

scientific article published in June 2008

Non-targeted effects of ionising radiation--implications for low dose risk.

scientific article

Numbers and proportions of leukemias in young people and adults induced by radiation of natural origin.

scientific article published on 21 February 2011

Occupational ionising radiation and risk of basal cell carcinoma in US radiologic technologists (1983-2005)

journal article published in 2015

Occupational radiation exposure and excess additive risk of cataract incidence in a cohort of US radiologic technologists

scientific article published on 02 December 2019

Occupational radiation exposure and glaucoma and macular degeneration in the US radiologic technologists.

scientific article published on 11 July 2018

On target cell numbers in radiation-induced H4-RET mediated papillary thyroid cancer

scientific article published on 01 September 2001

Parameter identifiability and redundancy in a general class of stochastic carcinogenesis models

scientific article

Parameter identifiability and redundancy: theoretical considerations

scientific article

Point/Counterpoint: low-dose radiation is beneficial, not harmful.

scientific article

Population-based risks of CNS tumors in survivors of childhood cancer: the British Childhood Cancer Survivor Study.

scientific article published on 15 November 2010

Potential funding crisis for the Radiation Effects Research Foundation

scientific article published in The Lancet

Potential increased risk of ischemic heart disease mortality with significant dose fractionation in the Canadian Fluoroscopy Cohort Study.

scientific article published on 20 October 2013

Projection of cancer risks from the Japanese atomic bomb survivors to the England and Wales population taking into account uncertainty in risk parameters

scientific article published in December 2000

Publisher Correction: Impact of uncertainties in exposure assessment on thyroid cancer risk among cleanup workers in Ukraine exposed due to the Chornobyl accident

correction of a scholarly article

RET/PTC and PAX8/PPARγ chromosomal rearrangements in post-Chernobyl thyroid cancer and their association with iodine-131 radiation dose and other characteristics.

scientific article published on 21 February 2013

Radiation Exposure and Mortality from Cardiovascular Disease and Cancer in Early NASA Astronauts.

scientific article

Radiation and Circulatory Disease

scientific article (publication date: 30 July 2016)

Radiation and the risk of chronic lymphocytic and other leukemias among chornobyl cleanup workers

scientific article published on 8 November 2012

Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study

scientific article

Radiation organ doses received in a nationwide cohort of U.S. radiologic technologists: methods and findings.

scientific article published on 31 October 2014

Radiation-induced leukemia at doses relevant to radiation therapy: modeling mechanisms and estimating risks

scientific article published in December 2006

Reference air kerma and kerma-area product as estimators of peak skin dose for fluoroscopically guided interventions.

scientific article

Relative risks of radiation-associated cancer: comparison of second cancer in therapeutically irradiated populations with the Japanese atomic bomb survivors

article

Reply to letter: Thyroid neoplasia after Chernobyl: A comment

scientific article published on 27 February 2019

Research recommendations toward a better understanding of the causes of childhood leukemia.

scientific article

Residential mobility and associated factors in relation to the assessment of exposure to naturally occurring radiation in studies of childhood cancer

scientific article

Review and meta-analysis of epidemiological associations between low/moderate doses of ionizing radiation and circulatory disease risks, and their possible mechanisms

scientific article

Risk of Thyroid Cancer after Adult Radiation Exposure: Time to Re-Assess?

scientific article published on December 19, 2012

Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database.

scientific article published on 03 December 2009

Risk of childhood leukemia after low-level exposure to ionizing radiation.

scientific article published on June 2010

Risk of thyroid follicular adenoma among children and adolescents in Belarus exposed to iodine-131 after the Chornobyl accident

scientific article published on 5 October 2015

Risk of thyroid nodules in residents of Belarus exposed to Chernobyl fallout as children and adolescents

scientific article published on 22 March 2017

Risk of thyroid nodules in subjects occupationally exposed to radiation: a cross sectional study

scientific article published on 01 August 1996

Risks associated with low doses and low dose rates of ionizing radiation: why linearity may be (almost) the best we can do

scientific article

Risks of brain tumour following treatment for cancer in childhood: modification by genetic factors, radiotherapy and chemotherapy

scientific article published in October 1998

Risks of non-cancer disease incidence and mortality in the Japanese atomic bomb survivors

scientific article published on 01 September 2004

River blindness: a success story under threat? ⬇️

scientific article published in September 2006

Second solid cancers after radiation therapy: a systematic review of the epidemiologic studies of the radiation dose-response relationship

scientific article

Selection effects in the Japanese bomb survivors

scientific article published on 01 June 1991

Spatial prediction of naturally occurring gamma radiation in Great Britain.

scientific article published on 18 August 2016

Stochastic modelling of colon cancer: is there a role for genomic instability?

scientific article published on 14 September 2006

Summary of Radiation Research Society Online 66<sup>th</sup> Annual Meeting, Symposium on "Epidemiology: Updates on epidemiological low dose studies", including Discussion

scientific article published on 04 January 2021

Systematic review and meta-analysis of circulatory disease from exposure to low-level ionizing radiation and estimates of potential population mortality risks

scientific article

Systematic review of worldwide variations of the prevalence of wheezing symptoms in children

scientific article

Systems biological and mechanistic modelling of radiation-induced cancer.

scientific article

Task-based measures of image quality and their relation to radiation dose and patient risk

scientific article

The bystander effect in C3H 10T cells and radon-induced lung cancer.

scientific article

The increase in thyroid cancer incidence during the last four decades is accompanied by a high frequency of BRAF mutations and a sharp increase in RAS mutations

scientific article

The proportion of childhood leukaemia incidence in Great Britain that may be caused by natural background ionizing radiation

scientific article published on 8 January 2009

The risk of non-melanoma skin cancer incidence in the Japanese atomic bomb survivors

scientific article published on 01 May 1997

The statistical power of epidemiological studies analyzing the relationship between exposure to ionizing radiation and cancer, with special reference to childhood leukemia and natural background radiation.

scientific article published on September 2010

Threshold and other departures from linear-quadratic curvature in the non-cancer mortality dose-response curve in the Japanese atomic bomb survivors

scientific article published on 19 June 2004

Thyroid Cancer and Benign Nodules After Exposure In Utero to Fallout From Chernobyl

scientific article published on 01 January 2019

Thyroid neoplasia risk is increased nearly 30 years after the Chernobyl accident.

scientific article published on 29 June 2017

Time variations in the risk of cancer following irradiation in childhood.

scientific article published in June 1991

Uncertainties in probabilistic nuclear accident consequence analysis

scientific article published on 01 December 1998

Updated estimates of the proportion of childhood leukaemia incidence in Great Britain that may be caused by natural background ionising radiation

scientific article

Variation of second cancer risk by family history of retinoblastoma among long-term survivors

scientific article published on 21 February 2012

Variations with time and age in the risks of solid cancer incidence after radiation exposure in childhood

scientific article

Work history and mortality risks in 90,268 US radiological technologists.

scientific article published on 22 May 2014

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