Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Lars Henning Engelholm

A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

scientific article

A supra-cellular model for coupling of bone resorption to formation during remodeling: lessons from two bone resorption inhibitors affecting bone formation differently

scientific article published on 12 December 2013

A urokinase receptor-associated protein with specific collagen binding properties

scientific article

Advances in targeted delivery of small interfering RNA using simple bioconjugates

scientific article published on 26 March 2014

C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

scientific article published on 12 May 2016

CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma.

scientific article published on 15 September 2017

Collagen density regulates the activity of tumor-infiltrating T cells

scientific article published on 12 March 2019

Complementary roles of intracellular and pericellular collagen degradation pathways in vivo.

scientific article

Complex determinants in specific members of the mannose receptor family govern collagen endocytosis

scientific article published on 05 February 2014

Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction.

scientific article

Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding

scientific article

Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis

scientific article

Differential binding of urokinase and peptide antagonists to the urokinase receptor: evidence from characterization of the receptor in four primate species

scientific article published in March 2001

Differential gene expression in human mammary carcinoma cells: identification of a new member of a receptor family.

scientific article

Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells

scientific article

Early reversal cells in adult human bone remodeling: osteoblastic nature, catabolic functions and interactions with osteoclasts.

scientific article published on 9 February 2016

Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis

scientific article published on 17 February 2012

Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

scientific article

Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation

scientific article

Gender affects skin wound healing in plasminogen deficient mice

scientific article

Identification of two estrogen regulated genes associated with growth regulation of human breast cancer.

scientific article

Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

scientific article published on 26 October 2018

Increased Expression of the Collagen Internalization Receptor uPARAP/Endo180 in the Stroma of Head and Neck Cancer

scientific article published on 22 December 2006

Inflammation and uPAR-Expression in Colorectal Liver Metastases in Relation to Growth Pattern and Neo-adjuvant Therapy.

scientific article published on 14 August 2015

Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo ⬇️

scientific article published on June 28, 2012

Loss of miR-10a activates lpo and collaborates with activated Wnt signaling in inducing intestinal neoplasia in female mice

scientific article

M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

scientific article

MT1-MMP and type II collagen specify skeletal stem cells and their bone and cartilage progeny.

scientific article

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

scientific article published on 02 February 2009

Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-13C]pyruvate

scientific article published on 16 January 2014

No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer

scientific article

Personalized B cell response to the <i>Lactobacillus rhamnosus GG</i> probiotic in healthy human subjects: a randomized trial

scientific article published on 01 November 2020

Phagocytosis of Collagen Fibrils by Fibroblasts In Vivo Is Independent of the uPARAP/Endo180 Receptor.

scientific article published on 6 December 2016

Plasmin-driven fibrinolysis facilitates skin tumor growth in a gender-dependent manner.

scientific article

Quantification of tissue inhibitor of metalloproteinases 2 in plasma from healthy donors and cancer patients.

scientific article published in May 2005

Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180

Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis

scientific article published on 14 February 2013

The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers.

scientific article

The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

scientific article (publication date: October 2015)

The collagen receptor uPARAP/Endo180.

scientific article published on January 2009

The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion.

scientific article published on 26 September 2016

The non-phagocytic route of collagen uptake: a distinct degradation pathway

scientific article

The number of regulatory T cells in transbronchial lung allograft biopsies is related to FoxP3 mRNA levels in bronchoalveolar lavage fluid and to the degree of acute cellular rejection ⬇️

scientific article published on August 19, 2013

Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and metastatic dissemination

scientific article published on 16 May 2013

Urokinase receptor-associated protein (uPARAP) is expressed in connection with malignant as well as benign lesions of the human breast and occurs in specific populations of stromal cells

scientific article published on 01 April 2002

uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

scientific article

uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis

scientific article published in Nature Communications

uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.

scientific article

Paulina is supported by:

About Paulina

Help