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List of works by Orion Weiner

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

scientific article

A chemical compass.

scientific article

A light-inducible organelle-targeting system for dynamically activating and inactivating signaling in budding yeast

scientific article published on June 12, 2013

A module for Rac temporal signal integration revealed with optogenetics.

scientific article published on 7 July 2017

A pharmacological cocktail for arresting actin dynamics in living cells

scientific article published on August 31, 2011

A size-invariant bud-duration timer enables robustness in yeast cell size control

scientific article published in PLoS ONE

Actin dynamics rapidly reset chemoattractant receptor sensitivity following adaptation in neutrophils

scientific article

An actin-based wave generator organizes cell motility

scientific article

An optogenetic gene expression system with rapid activation and deactivation kinetics

scientific article published on 12 January 2014

Cell confinement reveals a branched-actin independent circuit for neutrophil polarity

scientific article published on 10 October 2019

Compete globally, bud locally.

scientific article published on November 2009

Diffusion, capture and recycling of SCAR/WAVE and Arp2/3 complexes observed in cells by single-molecule imaging.

scientific article

Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis

scientific article

How should we be selecting our graduate students?

scientific article published on February 2014

How to understand and outwit adaptation

scientific article

Identifying network motifs that buffer front-to-back signaling in polarized neutrophils.

scientific article published on 9 May 2013

Illuminating cell signalling with optogenetic tools

scientific article

Joining forces: crosstalk between biochemical signalling and physical forces orchestrates cellular polarity and dynamics.

scientific article published in May 2018

Light-based feedback for controlling intracellular signaling dynamics.

scientific article

Light-based tuning of ligand half-life supports kinetic proofreading model of T cell signaling

scientific article published on 05 April 2019

Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils

scientific article published in July 2002

Live-cell imaging reveals enhancer-dependent transcription in the absence of enhancer proximity

scientific article published on 24 May 2019

Network crosstalk dynamically changes during neutrophil polarization.

scientific article published on May 2012

Nodal signaling has dual roles in fate specification and directed migration during germ layer segregation in zebrafish

scientific article published on 14 September 2018

Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1

scientific article

PIP3, PIP2, and cell movement--similar messages, different meanings?

scientific article

Positioning the cleavage furrow: All you need is Rho.

scientific article published on June 2016

Rac activation: P-Rex1 - a convergence point for PIP(3) and Gbetagamma?

scientific article

Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis

scientific article

Response to Bell et al.

scientific article published on July 2014

Self-organization of protrusions and polarity during eukaryotic chemotaxis.

scientific article published on 05 July 2014

Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains.

scientific article

Spatiotemporal control of cell signalling using a light-switchable protein interaction.

scientific article

Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal.

scientific article

The promise of optogenetics in cell biology: interrogating molecular circuits in space and time.

scientific article

The symphony of cell movement: how cells orchestrate diverse signals and forces to control migration

scientific article published on 05 August 2013

Two distinct functions for PI3-kinases in macropinocytosis

scientific article published on 10 July 2013

Use the force: membrane tension as an organizer of cell shape and motility

scientific article published on November 2, 2012

Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module.

scientific article