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List of works by Wai Leong Tam

A Near-Infrared Probe Tracks and Treats Lung Tumor Initiating Cells by Targeting HMOX2

scientific article published on 04 September 2019

A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages

scientific article

A comparison of the effects of environmental ammonia exposure on the Asian freshwater stingray Himantura signifer and the Amazonian freshwater stingray Potamotrygon motoro.

scientific article published in October 2003

A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes

scientific article (publication date: 22 September 2006)

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability

scientific article

B-MYB is essential for normal cell cycle progression and chromosomal stability of embryonic stem cells

scientific article

Cancer Stem Cells: Concepts, Challenges, and Opportunities for Cancer Therapy

scientific article published on 01 January 2019

Changes in salinity and ionic compositions can act as environmental signals to induce a reduction in ammonia production in the African lungfish Protopterus dolloi.

scientific article published on June 2005

Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence.

scientific article

Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer

scientific article published on 24 January 2019

Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition

scientific article

Effects of intra-peritoneal injection with NH4Cl, urea, or NH4Cl+urea on nitrogen excretion and metabolism in the African lungfish Protopterus dolloi

scientific article

Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing

scientific article published on 15 January 2018

Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer

scientific article published on 06 October 2021

Genomic landscape of lung adenocarcinoma in East Asians

scientific article published on 03 February 2020

IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.

scientific article

Identification of Tumor Initiating Cells by a Small Molecule Fluorescent Probe through Vimentin as the Biomarker.

scientific article published on 26 January 2018

Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma

scientific article published on 11 January 2021

Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies.

scientific article

Marine (Taeniura lymma) and freshwater (Himantura signifer) elasmobranchs synthesize urea for osmotic water retention

scientific article published on 17 May 2005

Methionine is a metabolic dependency of tumor-initiating cells

scientific article published on 06 May 2019

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

scientific article

New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation

scientific article published on 22 August 2019

Nitrogen metabolism in the African lungfish (Protopterus dolloi) aestivating in a mucus cocoon on land.

scientific article published in February 2004

Novel therapeutic targets on the horizon for lung cancer.

scientific article

Phenotypic and molecular features underlying neurodegeneration of motor neurons derived from spinal and bulbar muscular atrophy patients

scientific article published on 01 November 2018

Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells

scientific article

Publisher Correction: Methionine is a metabolic dependency of tumor-initiating cells

scientific article published on 01 June 2019

RCP is a human breast cancer-promoting gene with Ras-activating function

scientific article

Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity

scientific article published on 02 March 2022

Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells

scientific journal article

Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1

scientific article

Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages.

scientific article published on 18 September 2008

Slug and Sox9 cooperatively determine the mammary stem cell state

scientific article

Sox2: masterminding the root of cancer.

scientific article

T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways

scientific journal article

Tbx3 improves the germ-line competency of induced pluripotent stem cells

scientific article

The epigenetics of epithelial-mesenchymal plasticity in cancer

scientific article

The snakehead Channa asiatica accumulates alanine during aerial exposure, but is incapable of sustaining locomotory activities on land through partial amino acid catabolism.

scientific article

Tumour-initiating cell-specific miR-1246 and miR-1290 expression converge to promote non-small cell lung cancer progression.

scientific article published on 21 June 2016

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

scientific article

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