List of works - Ben Van Calster

A calibration hierarchy for risk models was defined: from utopia to empirical data

scientific article

A comparison between an ultrasound based prediction model (LR2) and the risk of ovarian malignancy algorithm (ROMA) to assess the risk of malignancy in women with an adnexal mass.

scientific article published on 27 January 2013

A mathematical model for interpretable clinical decision support with applications in gynecology

scientific article

A multicenter prospective external validation of the diagnostic performance of IOTA simple descriptors and rules to characterize ovarian masses

scientific article

A note on estimating the Cox-Snell R<sup>2</sup> from a reported C statistic (AUROC) to inform sample size calculations for developing a prediction model with a binary outcome

scientific article published on 07 December 2020

A novel approach to predict the likelihood of specific ovarian tumor pathology based on serum CA-125: a multicenter observational study

scientific article published on 9 September 2011

A pictorial essay on fetal rabbit anatomy using micro-ultrasound and magnetic resonance imaging.

scientific article

An application of methods for the probabilistic three-class classification of pregnancies of unknown location

scientific article published on 20 January 2009

Antenatal maternal anxiety is related to HPA-axis dysregulation and self-reported depressive symptoms in adolescence: a prospective study on the fetal origins of depressed mood.

scientific article

Assessing the discriminative ability of risk models for more than two outcome categories

scientific article published in October 2012

Assessing the incremental value of diagnostic and prognostic markers: a review and illustration

scientific article published on 05 July 2011

Axillary lymph node status of operable breast cancers by combined steroid receptor and HER-2 status: triple positive tumours are more likely lymph node positive

scientific article published on 9 February 2008

Calibration of Risk Prediction Models

article

Calibration: the Achilles heel of predictive analytics

scientific article published on 16 December 2019

Characterizing Ovarian Pathology

scientific article published on 01 May 2012

Chlamydia trachomatis infection in patients attending an Early Pregnancy Unit: prevalence, symptoms, pregnancy location and viability

scientific article published on January 2008

Classifying ovarian tumors using Bayesian Multi-Layer Perceptrons and Automatic Relevance Determination: a multi-center study.

scientific article published in January 2006

Clinical information does not improve the performance of mathematical models in predicting the outcome of pregnancies of unknown location

scientific article published on 17 May 2007

Collagen plug sealing of iatrogenic fetal membrane defects after fetoscopic surgery for congenital diaphragmatic hernia.

scientific article published in January 2014

Consequences of relying on statistical significance: some illustrations

scientific article published on 13 February 2018

Demystifying AI in healthcare

scientific article published on 09 September 2020

Developing risk models for multicenter data using standard logistic regression produced suboptimal predictions: A simulation study

scientific article published on 20 January 2020

Discrimination ability of prediction models for ordinal outcomes: relationships between existing measures and a new measure

scientific article published on 19 June 2012

Discrimination between benign and malignant adnexal masses by specialist ultrasound examination versus serum CA-125.

scientific article published on 13 November 2007

Ectopic pregnancy: using the hCG ratio to select women for expectant or medical management

scientific article published on 13 January 2011

Evaluating a New Marker for Risk Prediction Using the Test Tradeoff: An Update

scientific article published on 22 March 2012

Evaluation of Imputation Methods in Ovarian Tumor Diagnostic Models Using Generalized Linear Models and Support Vector Machines

scientific article published on 15 July 2009

Evaluation of markers and risk prediction models: overview of relationships between NRI and decision-analytic measures

scientific article

Extending the c-statistic to nominal polytomous outcomes: the Polytomous Discrimination Index

scientific article published on 26 June 2012

External validation of ADNEX model for diagnosing ovarian cancer: evaluating performance of differentiation between tumor subgroups

scientific article published on 22 December 2016

External validation of diagnostic models to estimate the risk of malignancy in adnexal masses

scientific article

External validation of mathematical models to distinguish between benign and malignant adnexal tumors: a multicenter study by the International Ovarian Tumor Analysis Group

scientific article published in August 2007

Flawed external validation study of the ADNEX model to diagnose ovarian cancer

scientific article published on 14 September 2016

Graphical assessment of incremental value of novel markers in prediction models: From statistical to decision analytical perspectives.

scientific article published on 18 July 2014

Histology obtained by needle biopsy gives additional information on the prognosis of hepatocellular carcinoma.

scientific article published on 30 April 2012

Impact of predictor measurement heterogeneity across settings on the performance of prediction models: A measurement error perspective

scientific article published on 31 May 2019

In Early-Stage Breast Cancer, the Estrogen Receptor Interacts With Correlation Between Human Epidermal Growth Factor Receptor 2 Status and Age at Diagnosis, Tumor Grade, and Lymph Node Involvement

scientific article published on 01 April 2008

Inclusion of CA-125 does not improve mathematical models developed to distinguish between benign and malignant adnexal tumors

scientific article published on 13 August 2007

Integrated discrimination improvement and probability-sensitive AUC variants

scientific article published in January 2010

Integrating pretreatment diffusion weighted MRI into a multivariable prognostic model for head and neck squamous cell carcinoma

scientific article

International Endometrial Tumor Analysis (IETA) terminology in women with postmenopausal bleeding and sonographic endometrial thickness ≥4.5 mm: an agreement and reliability study

scientific article

Logistic regression model to distinguish between the benign and malignant adnexal mass before surgery: a multicenter study by the International Ovarian Tumor Analysis Group.

scientific article

Long-term cognitive and cardiac outcomes after prenatal exposure to chemotherapy in children aged 18 months or older: an observational study.

scientific article published on 10 February 2012

Lymph Node Ratio Better Predicts Disease-Free Survival in Node-Positive Breast Cancer Than the Number of Positive Lymph Nodes

scientific article published on 31 August 2009

Medidas del rendimiento de modelos de predicción y marcadores pronósticos: evaluación de las predicciones y clasificaciones

scientific article published in September 2011

Methodological Issues in the Development of a Prediction Tool for First-Trimester Outcomes

scientific article published on 24 October 2020

NICE guidance on ectopic pregnancy and miscarriage restricts access and choice and may be clinically unsafe

scientific article published in the British Medical Journal

Net reclassification improvement and integrated discrimination improvement require calibrated models: relevance from a marker and model perspective

scientific article published on 01 August 2014

Parathyroid hormone is a plausible mediator for the metabolic syndrome in the morbidly obese: a cross-sectional study

scientific article

Pelvic exenterations for gynecological malignancies: a study of 36 cases.

scientific article published on June 2012

Performance of the American College of Obstetricians and Gynecologistsʼ Ovarian Tumor Referral Guidelines With a Multivariate Index Assay

scientific article published on 01 November 2011

Polytomous diagnosis of ovarian tumors as benign, borderline, primary invasive or metastatic: development and validation of standard and kernel-based risk prediction models.

scientific article

Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal

scientific article published on 07 April 2020

Predictive analytics in health care: how can we know it works?

scientific article published on 01 December 2019

Presurgical diagnosis of adnexal tumours using mathematical models and scoring systems: a systematic review and meta-analysis.

scientific article

Prognosis of women with primary breast cancer diagnosed during pregnancy: results from an international collaborative study

scientific article published on 22 April 2013

Prognostic impact of baseline serum C-reactive protein in patients with metastatic renal cell carcinoma (RCC) treated with sunitinib.

scientific article published on 15 January 2014

Prognostic value of serum HE4 levels and risk of ovarian malignancy algorithm scores at the time of ovarian cancer diagnosis

scientific article published on September 2014

Prospective internal validation of mathematical models to predict malignancy in adnexal masses: results from the international ovarian tumor analysis study

scientific article published in January 2009

Prospective study to assess short-term intra-articular and tenosynovial changes in the aromatase inhibitor-associated arthralgia syndrome

scientific article published on 12 May 2008

Random-effects meta-analysis of the clinical utility of tests and prediction models.

scientific article published on 25 March 2018

Re: “Diagnostic Accuracies of the Ultrasound and Magnetic Resonance Imaging ADNEX Scoring Systems for Ovarian Adnexal Mass: Systematic Review and Meta-Analysis”

scientific article published in 2021

Regression shrinkage methods for clinical prediction models do not guarantee improved performance: Simulation study

scientific article published on 13 May 2020

Relationship between age and axillary lymph node involvement in women with breast cancer

scientific article published on 18 May 2009

Reply to D. Crivellari et al

scientific article published on 02 December 2013

Reporting and Interpreting Decision Curve Analysis: A Guide for Investigators

scientific article published on 19 September 2018

Risk prediction models for discrete ordinal outcomes: Calibration and the impact of the proportional odds assumption

scientific article published in 2021

Risk prediction with machine learning and regression methods.

scientific article published on 25 February 2014

Role of Neoadjuvant Chemotherapy in the Management of Stage IIIC–IV Ovarian Cancer: Survey Results from the Members of the European Society of Gynecological Oncology

scientific article published on 01 March 2012

Sample size considerations and predictive performance of multinomial logistic prediction models

scientific article published on 6 January 2019

Screening for data clustering in multicenter studies: the residual intraclass correlation.

scientific article

Sensitivity and specificity can change in opposite directions when new predictive markers are added to risk models

scientific article

Simple dichotomous updating methods improved the validity of polytomous prediction models

scientific article published on 9 July 2013

Subjective assessment by ultrasound is superior to the risk of malignancy index (RMI) or the risk of ovarian malignancy algorithm (ROMA) in discriminating benign from malignant adnexal masses.

scientific article published on 5 January 2012

Systematic review and critical appraisal of prediction models for diagnosis and prognosis of COVID-19 infection

scientific article (preprint)

The hCG ratio can predict the ultimate viability of the intrauterine pregnancies of uncertain viability in the pregnancy of unknown location population

scientific article published on 10 June 2008

The harm of class imbalance corrections for risk prediction models: illustration and simulation using logistic regression

scientific article published on 10 June 2022

The independent effect of tumor size in predicting ovarian malignancy

scientific article published on 20 March 2012

The use of lymph vessel markers to predict endometrial cancer outcome

scientific article published in April 2010

The use of serum inhibin A and activin A levels in predicting the outcome of 'pregnancies of unknown location'.

scientific article published on 23 June 2009

Treatment of breast cancer during pregnancy: an observational study

scientific article

Triple negative breast cancer: clinical characteristics in the different histological subtypes.

scientific article published on 15 February 2013

Validation and updating of risk models based on multinomial logistic regression

scientific article published on 08 February 2017

Validation of models to diagnose ovarian cancer in patients managed surgically or conservatively: multicentre cohort study

scientific article published on 30 July 2020

What Determines the Need to Morcellate the Uterus during Total Laparoscopic Hysterectomy?

scientific article published on 08 November 2008

What is the value of preoperative bimanual pelvic examination in women undergoing laparoscopic total hysterectomy?

scientific article published on 01 May 2007

Wilms tumor gene 1 (WT1) is a prognostic marker in high-grade uterine sarcoma

scientific article published on February 2011

List of works by Ben Van Calster

A calibration hierarchy for risk models was defined: from utopia to empirical data

A comparison between an ultrasound based prediction model (LR2) and the risk of ovarian malignancy algorithm (ROMA) to assess the risk of malignancy in women with an adnexal mass.

A mathematical model for interpretable clinical decision support with applications in gynecology

A multicenter prospective external validation of the diagnostic performance of IOTA simple descriptors and rules to characterize ovarian masses

A note on estimating the Cox-Snell R<sup>2</sup> from a reported C statistic (AUROC) to inform sample size calculations for developing a prediction model with a binary outcome

A novel approach to predict the likelihood of specific ovarian tumor pathology based on serum CA-125: a multicenter observational study

A pictorial essay on fetal rabbit anatomy using micro-ultrasound and magnetic resonance imaging.

An application of methods for the probabilistic three-class classification of pregnancies of unknown location

Antenatal maternal anxiety is related to HPA-axis dysregulation and self-reported depressive symptoms in adolescence: a prospective study on the fetal origins of depressed mood.

Assessing the discriminative ability of risk models for more than two outcome categories

Assessing the incremental value of diagnostic and prognostic markers: a review and illustration

Axillary lymph node status of operable breast cancers by combined steroid receptor and HER-2 status: triple positive tumours are more likely lymph node positive

Calibration of Risk Prediction Models

Calibration: the Achilles heel of predictive analytics

Characterizing Ovarian Pathology

Chlamydia trachomatis infection in patients attending an Early Pregnancy Unit: prevalence, symptoms, pregnancy location and viability

Classifying ovarian tumors using Bayesian Multi-Layer Perceptrons and Automatic Relevance Determination: a multi-center study.

Clinical information does not improve the performance of mathematical models in predicting the outcome of pregnancies of unknown location

Collagen plug sealing of iatrogenic fetal membrane defects after fetoscopic surgery for congenital diaphragmatic hernia.

Consequences of relying on statistical significance: some illustrations

Demystifying AI in healthcare

Developing risk models for multicenter data using standard logistic regression produced suboptimal predictions: A simulation study

Discrimination ability of prediction models for ordinal outcomes: relationships between existing measures and a new measure

Discrimination between benign and malignant adnexal masses by specialist ultrasound examination versus serum CA-125.

Ectopic pregnancy: using the hCG ratio to select women for expectant or medical management

Evaluating a New Marker for Risk Prediction Using the Test Tradeoff: An Update

Evaluation of Imputation Methods in Ovarian Tumor Diagnostic Models Using Generalized Linear Models and Support Vector Machines

Evaluation of markers and risk prediction models: overview of relationships between NRI and decision-analytic measures

Extending the c-statistic to nominal polytomous outcomes: the Polytomous Discrimination Index

External validation of ADNEX model for diagnosing ovarian cancer: evaluating performance of differentiation between tumor subgroups

External validation of diagnostic models to estimate the risk of malignancy in adnexal masses

External validation of mathematical models to distinguish between benign and malignant adnexal tumors: a multicenter study by the International Ovarian Tumor Analysis Group

Flawed external validation study of the ADNEX model to diagnose ovarian cancer

Graphical assessment of incremental value of novel markers in prediction models: From statistical to decision analytical perspectives.

Histology obtained by needle biopsy gives additional information on the prognosis of hepatocellular carcinoma.

Impact of predictor measurement heterogeneity across settings on the performance of prediction models: A measurement error perspective

In Early-Stage Breast Cancer, the Estrogen Receptor Interacts With Correlation Between Human Epidermal Growth Factor Receptor 2 Status and Age at Diagnosis, Tumor Grade, and Lymph Node Involvement

Inclusion of CA-125 does not improve mathematical models developed to distinguish between benign and malignant adnexal tumors

Integrated discrimination improvement and probability-sensitive AUC variants

Integrating pretreatment diffusion weighted MRI into a multivariable prognostic model for head and neck squamous cell carcinoma

International Endometrial Tumor Analysis (IETA) terminology in women with postmenopausal bleeding and sonographic endometrial thickness ≥4.5 mm: an agreement and reliability study

Logistic regression model to distinguish between the benign and malignant adnexal mass before surgery: a multicenter study by the International Ovarian Tumor Analysis Group.

Long-term cognitive and cardiac outcomes after prenatal exposure to chemotherapy in children aged 18 months or older: an observational study.

Lymph Node Ratio Better Predicts Disease-Free Survival in Node-Positive Breast Cancer Than the Number of Positive Lymph Nodes

Medidas del rendimiento de modelos de predicción y marcadores pronósticos: evaluación de las predicciones y clasificaciones

Methodological Issues in the Development of a Prediction Tool for First-Trimester Outcomes

NICE guidance on ectopic pregnancy and miscarriage restricts access and choice and may be clinically unsafe

Net reclassification improvement and integrated discrimination improvement require calibrated models: relevance from a marker and model perspective

Parathyroid hormone is a plausible mediator for the metabolic syndrome in the morbidly obese: a cross-sectional study

Pelvic exenterations for gynecological malignancies: a study of 36 cases.

Performance of the American College of Obstetricians and Gynecologistsʼ Ovarian Tumor Referral Guidelines With a Multivariate Index Assay

Polytomous diagnosis of ovarian tumors as benign, borderline, primary invasive or metastatic: development and validation of standard and kernel-based risk prediction models.

Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal

Predictive analytics in health care: how can we know it works?

Presurgical diagnosis of adnexal tumours using mathematical models and scoring systems: a systematic review and meta-analysis.

Prognosis of women with primary breast cancer diagnosed during pregnancy: results from an international collaborative study

Prognostic impact of baseline serum C-reactive protein in patients with metastatic renal cell carcinoma (RCC) treated with sunitinib.

Prognostic value of serum HE4 levels and risk of ovarian malignancy algorithm scores at the time of ovarian cancer diagnosis

Prospective internal validation of mathematical models to predict malignancy in adnexal masses: results from the international ovarian tumor analysis study

Prospective study to assess short-term intra-articular and tenosynovial changes in the aromatase inhibitor-associated arthralgia syndrome

Random-effects meta-analysis of the clinical utility of tests and prediction models.

Re: “Diagnostic Accuracies of the Ultrasound and Magnetic Resonance Imaging ADNEX Scoring Systems for Ovarian Adnexal Mass: Systematic Review and Meta-Analysis”

Regression shrinkage methods for clinical prediction models do not guarantee improved performance: Simulation study

Relationship between age and axillary lymph node involvement in women with breast cancer

Reply to D. Crivellari et al

Reporting and Interpreting Decision Curve Analysis: A Guide for Investigators

Risk prediction models for discrete ordinal outcomes: Calibration and the impact of the proportional odds assumption

Risk prediction with machine learning and regression methods.

Role of Neoadjuvant Chemotherapy in the Management of Stage IIIC–IV Ovarian Cancer: Survey Results from the Members of the European Society of Gynecological Oncology

Sample size considerations and predictive performance of multinomial logistic prediction models

Screening for data clustering in multicenter studies: the residual intraclass correlation.

Sensitivity and specificity can change in opposite directions when new predictive markers are added to risk models

Simple dichotomous updating methods improved the validity of polytomous prediction models

Subjective assessment by ultrasound is superior to the risk of malignancy index (RMI) or the risk of ovarian malignancy algorithm (ROMA) in discriminating benign from malignant adnexal masses.

Systematic review and critical appraisal of prediction models for diagnosis and prognosis of COVID-19 infection

The hCG ratio can predict the ultimate viability of the intrauterine pregnancies of uncertain viability in the pregnancy of unknown location population

The harm of class imbalance corrections for risk prediction models: illustration and simulation using logistic regression

The independent effect of tumor size in predicting ovarian malignancy

The use of lymph vessel markers to predict endometrial cancer outcome