Search filters

List of works by Ali Saber Abdelhameed

A Comprehensive Spectroscopic and Computational Investigation to Probe the Interaction of Antineoplastic Drug Nordihydroguaiaretic Acid with Serum Albumins

scientific article

A Spectroscopic Approach to Investigate the Molecular Interactions between the Newly Approved Irreversible ErbB blocker "Afatinib" and Bovine Serum Albumin

scientific article published on 11 January 2016

A Stability-Indicating HPLC-DAD Method for Determination of Stiripentol: Development, Validation, Kinetics, Structure Elucidation and Application to Commercial Dosage Form

scientific article

A Validated HPLC-DAD Method for Simultaneous Determination of Etodolac and Pantoprazole in Rat Plasma

scholarly article in Journal of Chemistry, 2014

A biophysical and computational study unraveling the molecular interaction mechanism of a new Janus kinase inhibitor Tofacitinib with bovine serum albumin

scientific article published on 9 December 2016

A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate.

scientific article published on 26 February 2016

A highly efficient and sensitive LC-MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study

scientific article published on 19 December 2015

A multitechnique approach to probe the interaction of a therapeutic tyrosine kinase inhibitor nintedanib and bovine serum albumin

scientific article published on 3 January 2017

An LC-MS/MS method for rapid and sensitive high-throughput simultaneous determination of various protein kinase inhibitors in human plasma.

scientific article

An asymmetric and slightly dimerized structure for the tetanus toxoid protein used in glycoconjugate vaccines.

scientific article

Anti-Parkinsonian L-Dopa can also act as anti-systemic amyloidosis-A mechanistic exploration.

scientific article published on 7 March 2017

Antiproliferative activity and possible mechanism of action of certain 5-methoxyindole tethered C-5 functionalized isatins

scientific article published on 27 August 2019

Ascorbic acid inhibits human insulin aggregation and protects against amyloid induced cytotoxicity.

scientific article

Binding of Janus kinase inhibitor tofacitinib with human serum albumin: multi-technique approach.

scientific article published on 6 October 2015

Biophysical Interactions of Novel Oleic Acid Conjugate and its Anticancer Potential in HeLa Cells.

scientific article

Biophysical and In Silico Studies of the Interaction between the Anti-Viral Agents Acyclovir and Penciclovir, and Human Serum Albumin

scientific article published on 5 November 2017

Biophysical insight reveals tannic acid as amyloid inducer and conformation transformer from amorphous to amyloid aggregates in Concanavalin A (ConA).

scientific article published on 11 April 2017

Cationic surfactant mediated fibrillogenesis in bovine liver catalase: a biophysical approach

scientific article published on 2 August 2017

Characterization of Capsular Polysaccharides and Their Glycoconjugates by Hydrodynamic Methods

scientific article published on 01 January 2015

Characterization of Stable and Reactive Metabolites of the Anticancer Drug, Ensartinib, in Human Liver Microsomes Using LC-MS/MS: An in silico and Practical Bioactivation Approach

scientific article published on 30 November 2020

Comparative ANNs with different input layers and GA-PLS study for simultaneous spectrofluorimetric determination of melatonin and pyridoxine HCl in the presence of melatonin’s main impurity.

scientific article published on 14 January 2013

Correction: A Comprehensive Spectroscopic and Computational Investigation to Probe the Interaction of Antineoplastic Drug Nordihydroguaiaretic Acid with Serum Albumins

scientific article

Deciphering the enhanced inhibitory, disaggregating and cytoprotective potential of promethazine towards amyloid fibrillation.

scientific article published on 16 August 2017

Design, synthesis and in vitro anticancer evaluation of a stearic acid-based ester conjugate

scientific article published on June 1, 2013

Erratum to: Biophysical Interactions of Novel Oleic Acid Conjugate and its Anticancer Potential in HeLa Cells

scientific article published on 01 May 2015

Extended Fujita approach to the molecular weight distribution of polysaccharides and other polymeric systems

scientific article

Fluorescence spectroscopic and molecular docking studies of the binding interaction between the new anaplastic lymphoma kinase inhibitor crizotinib and bovine serum albumin

scientific article published on 5 August 2016

HPLC method with monolithic column for simultaneous determination of irbesartan and hydrochlorothiazide in tablets

scientific article published on 01 June 2014

High Throughput Quantitative Bioanalytical LC/MS/MS Determination of Gemifloxacin in Human Urine

scholarly article in Journal of Chemistry, 2013

Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation

scientific article published on 28 October 2020

Induced in-source fragmentation pattern of certain novel (1Z,2E)-N-(aryl)propanehydrazonoyl chlorides by electrospray mass spectrometry (ESI-MS/MS).

scientific article published on 25 January 2013

Insight into the Interaction between the HIV-1 Integrase Inhibitor Elvitegravir and Bovine Serum Albumin: A Spectroscopic Study

article

Interaction of catecholamine precursor l-Dopa with lysozyme: A biophysical insight.

scientific article published on 17 November 2017

Interaction of new kinase inhibitors cabozantinib and tofacitinib with human serum alpha-1 acid glycoprotein. A comprehensive spectroscopic and molecular Docking approach

scientific article published on 25 January 2016

Interplay of multiple interaction forces: Binding of tyrosine kinase inhibitor nintedanib with human serum albumin.

scientific article

Investigating the site selective binding of busulfan to human serum albumin: Biophysical and molecular docking approaches.

scientific article published on 5 October 2017

Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling

scientific article

LC-MS/MS Estimation of the Anti-Cancer Agent Tandutinib Levels in Human Liver Microsomes: Metabolic Stability Evaluation Assay

scientific article published on 23 October 2020

Metabolic Stability Assessment of New PARP Inhibitor Talazoparib Using Validated LC-MS/MS Methodology: In silico Metabolic Vulnerability and Toxicity Studies

scientific article published on 25 February 2020

Micellar Enhanced Spectrofluorimetric Method for the Determination of Ponatinib in Human Plasma and Urine via Cremophor RH 40 as Sensing Agent.

scientific article published on 31 December 2015

Multistage fragmentation of ion trap mass spectrometry system and pseudo-MS3 of triple quadrupole mass spectrometry characterize certain (E)-3-(dimethylamino)-1-arylprop-2-en-1-ones: a comparative study

scientific article published on 19 February 2014

Nanosuspension: An Emerging Trend for Bioavailability Enhancement of Etodolac

Novel BTK inhibitor acalabrutinib (ACP-196) tightly binds to site I of the human serum albumin as observed by spectroscopic and computational studies

scientific article published on 18 January 2019

Polyols (Glycerol and Ethylene glycol) mediated amorphous aggregate inhibition and secondary structure restoration of metalloproteinase-conalbumin (ovotransferrin).

scientific article published on 12 October 2016

Probing the interaction of cephalosporin antibiotic-ceftazidime with human serum albumin: A biophysical investigation.

scientific article published on 7 July 2017

Pseudo-MS3Approach Using Electrospray Mass Spectrometry (ESI-MS/MS) to Characterize Certain (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]hydrazinecarboxamide Derivatives

scholarly article in Journal of Chemistry, 2014

Reactive intermediates and bioactivation pathways characterization of avitinib by LC-MS/MS: In vitro metabolic investigation

scientific article published on 17 November 2018

Simultaneous quantitative analysis of olmesartan, amlodipine and hydrochlorothiazide in their combined dosage form utilizing classical and alternating least squares based chemometric methods.

scientific article published on March 2016

Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein

scientific article published on 26 October 2016

Solution properties of capsular polysaccharides from Streptococcus pneumoniae

scientific article

Spectroscopic and molecular docking studies reveal binding characteristics of nazartinib (EGF816) to human serum albumin

scientific article published on 15 January 2020

Structure of amyloid oligomers and their mechanisms of toxicities: Targeting amyloid oligomers using novel therapeutic approaches.

scientific article published on 2 March 2016

Synthesis, Spectroscopic Identification and Molecular Docking of Certain N-(2-{[2-(1H-Indol-2-ylcarbonyl) Hydrazinyl](oxo)Acetylphenyl)Acetamides and N-[2-(2-{[2-(Acetylamino)Phenyl](oxo)Acetylhydrazinyl)-2-Oxoethyl]-1H-Indole-2-Carboxamides: New An

scientific article published on 29 April 2018