List of works - Jeremy T. Smith

A role for kisspeptins in the regulation of gonadotropin secretion in the mouse.

scientific article

Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty.

scientific article published in December 2005

An eGFP-expressing subpopulation of growth hormone secretagogue receptor cells are distinct from kisspeptin, tyrosine hydroxylase, and RFamide-related peptide neurons in mice.

scientific article published on 04 July 2013

Characterizing the neuroendocrine and ovarian defects of androgen receptor-knockout female mice.

scientific article published on 23 July 2013

Developmental changes in plasma leptin and hypothalamic leptin receptor expression in the rat: peripubertal changes and the emergence of sex differences.

scientific article

Developmental increases in plasma leptin binding activity and tissue Ob-Re mRNA expression in the rat.

scientific article

Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation

scientific article

Diurnal regulation of hypothalamic kisspeptin is disrupted during mouse pregnancy

scientific article published on 11 April 2016

Effect of RF-amide-related peptide-3 on luteinizing hormone and follicle-stimulating hormone synthesis and secretion in ovine pituitary gonadotropes.

scientific article published on 6 October 2009

Effects of Season and Estradiol on KNDy Neuron Peptides, Colocalization With D2 Dopamine Receptors, and Dopaminergic Inputs in the Ewe.

scientific article published on 16 January 2017

Elevated KiSS-1 expression in the arcuate nucleus prior to the cyclic preovulatory gonadotrophin-releasing hormone/lutenising hormone surge in the ewe suggests a stimulatory role for kisspeptin in oestrogen-positive feedback.

scientific article published in October 2006

Evidence that Neurokinin B Controls Basal Gonadotropin-Releasing Hormone Secretion but Is Not Critical for Estrogen-Positive Feedback in Sheep

scientific article published on 12 February 2015

Evidence that RF-amide related peptide-3 is not a mediator of the inhibitory effects of psychosocial stress on gonadotrophin secretion in ovariectomised ewes

scientific article published on 01 March 2011

Gonadotropin inhibitory hormone function in mammals.

scientific article published on 07 January 2010

Gonadotropin-inhibitory hormone (GnIH) secretion into the ovine hypophyseal portal system.

scientific article

Gonadotropin-inhibitory hormone is a hypothalamic peptide that provides a molecular switch between reproduction and feeding

scientific article published on 25 January 2012

Haplosufficient genomic androgen receptor signaling is adequate to protect female mice from induction of polycystic ovary syndrome features by prenatal hyperandrogenization.

scientific article published on 2 February 2015

Hypothalamic expression of KISS1 and gonadotropin inhibitory hormone genes during the menstrual cycle of a non-human primate.

scientific article

Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity

scientific article

Increased fetal glucocorticoid exposure delays puberty onset in postnatal life

scientific article published on 01 July 2000

KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season.

scientific article published on 21 December 2006

KiSS-1 neurones are direct targets for leptin in the ob/ob mouse.

scientific article published on April 2006

Kiss1 neurons in the forebrain as central processors for generating the preovulatory luteinizing hormone surge.

scientific article published in June 2006

Kisspeptin Activation of Gonadotropin Releasing Hormone Neurons and Regulation of KiSS-1 mRNA in the Male Rat

article

Kisspeptin Is Essential for the Full Preovulatory LH Surge and Stimulates GnRH Release from the Isolated Ovine Median Eminence

article

Kisspeptin Is Present in Ovine Hypophysial Portal Blood But Does Not Increase during the Preovulatory Luteinizing Hormone Surge: Evidence that Gonadotropes Are Not Direct Targets of Kisspeptinin Vivo

article

Kisspeptin Stimulates Growth Hormone Release by Utilizing Neuropeptide Y Pathways and Is Dependent on the Presence of Ghrelin in the Ewe.

scientific article published in October 2017

Kisspeptin and energy balance in reproduction

scientific article

Kisspeptin and seasonality in sheep.

scientific article published on 16 September 2008

Kisspeptin cells in the ewe brain respond to leptin and communicate with neuropeptide Y and proopiomelanocortin cells

scientific article

Kisspeptin impacts on circadian and ultradian rhythms of core body temperature: Evidence in kisspeptin receptor knockout and kisspeptin knockdown mice

scientific article published in 2022

Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B.

scientific article

Kisspeptin neurons in the ovine arcuate nucleus and preoptic area are involved in the preovulatory luteinizing hormone surge.

scientific article published on 9 October 2009

Kisspeptin signaling is required for the luteinizing hormone response in anestrous ewes following the introduction of males

scientific article

Kisspeptin signalling in the brain: steroid regulation in the rodent and ewe.

scientific article published on 19 April 2007

Kisspeptin synchronizes preovulatory surges in cyclical ewes and causes ovulation in seasonally acyclic ewes

scientific article published on 16 August 2007

Leptin distribution and metabolism in the pregnant rat: transplacental leptin passage increases in late gestation but is reduced by excess glucocorticoids

scientific article

Leptin receptor expression in the rat placenta: changes in ob-ra, ob-rb, and ob-re with gestational age and suppression by glucocorticoids

scientific journal article

Maternal vitamin D deficiency alters fetal brain development in the BALB/c mouse

scientific article

Neonatal overfeeding induces early decline of the ovarian reserve: Implications for the role of leptin.

scientific article published on 3 May 2016

Ontogeny of clock and KiSS-1 metastasis-suppressor (Kiss1) gene expression in the prepubertal mouse hypothalamus.

scientific article published on 21 December 2016

Placental and fetal growth retardation following partial progesterone withdrawal in rat pregnancy.

scientific article

Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion

scientific article

Pregnancy-induced adaptations of the central circadian clock and maternal glucocorticoids

scientific article

Preweaning over- and underfeeding alters onset of puberty in the rat without affecting kisspeptin.

scientific article published on 10 May 2012

Regulation of Kiss1 gene expression in the brain of the female mouse.

scientific article published on 26 May 2005

Regulation of the neuroendocrine reproductive axis by kisspeptin-GPR54 signaling.

scientific article

Seasonal and cyclical change in the luteinizing hormone response to kisspeptin in the ewe.

scientific article published on 7 July 2009

Sex steroid control of hypothalamic Kiss1 expression in sheep and rodents: comparative aspects.

scientific article published on 26 August 2008

Sex steroid regulation of kisspeptin circuits.

scientific article published on January 2013

Unaltered Hypothalamic Metabolic Gene Expression in Kiss1r Knockout Mice Despite Obesity and Reduced Energy Expenditure

scientific article published on 7 September 2016

List of works by Jeremy T. Smith

A role for kisspeptins in the regulation of gonadotropin secretion in the mouse.

Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty.

An eGFP-expressing subpopulation of growth hormone secretagogue receptor cells are distinct from kisspeptin, tyrosine hydroxylase, and RFamide-related peptide neurons in mice.

Characterizing the neuroendocrine and ovarian defects of androgen receptor-knockout female mice.

Developmental changes in plasma leptin and hypothalamic leptin receptor expression in the rat: peripubertal changes and the emergence of sex differences.

Developmental increases in plasma leptin binding activity and tissue Ob-Re mRNA expression in the rat.

Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation

Diurnal regulation of hypothalamic kisspeptin is disrupted during mouse pregnancy

Effect of RF-amide-related peptide-3 on luteinizing hormone and follicle-stimulating hormone synthesis and secretion in ovine pituitary gonadotropes.

Effects of Season and Estradiol on KNDy Neuron Peptides, Colocalization With D2 Dopamine Receptors, and Dopaminergic Inputs in the Ewe.

Elevated KiSS-1 expression in the arcuate nucleus prior to the cyclic preovulatory gonadotrophin-releasing hormone/lutenising hormone surge in the ewe suggests a stimulatory role for kisspeptin in oestrogen-positive feedback.

Evidence that Neurokinin B Controls Basal Gonadotropin-Releasing Hormone Secretion but Is Not Critical for Estrogen-Positive Feedback in Sheep

Evidence that RF-amide related peptide-3 is not a mediator of the inhibitory effects of psychosocial stress on gonadotrophin secretion in ovariectomised ewes

Gonadotropin inhibitory hormone function in mammals.

Gonadotropin-inhibitory hormone (GnIH) secretion into the ovine hypophyseal portal system.

Gonadotropin-inhibitory hormone is a hypothalamic peptide that provides a molecular switch between reproduction and feeding

Haplosufficient genomic androgen receptor signaling is adequate to protect female mice from induction of polycystic ovary syndrome features by prenatal hyperandrogenization.

Hypothalamic expression of KISS1 and gonadotropin inhibitory hormone genes during the menstrual cycle of a non-human primate.

Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity

Increased fetal glucocorticoid exposure delays puberty onset in postnatal life

KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season.

KiSS-1 neurones are direct targets for leptin in the ob/ob mouse.

Kiss1 neurons in the forebrain as central processors for generating the preovulatory luteinizing hormone surge.

Kisspeptin Activation of Gonadotropin Releasing Hormone Neurons and Regulation of KiSS-1 mRNA in the Male Rat

Kisspeptin Is Essential for the Full Preovulatory LH Surge and Stimulates GnRH Release from the Isolated Ovine Median Eminence

Kisspeptin Is Present in Ovine Hypophysial Portal Blood But Does Not Increase during the Preovulatory Luteinizing Hormone Surge: Evidence that Gonadotropes Are Not Direct Targets of Kisspeptinin Vivo

Kisspeptin Stimulates Growth Hormone Release by Utilizing Neuropeptide Y Pathways and Is Dependent on the Presence of Ghrelin in the Ewe.

Kisspeptin and energy balance in reproduction

Kisspeptin and seasonality in sheep.

Kisspeptin cells in the ewe brain respond to leptin and communicate with neuropeptide Y and proopiomelanocortin cells

Kisspeptin impacts on circadian and ultradian rhythms of core body temperature: Evidence in kisspeptin receptor knockout and kisspeptin knockdown mice

Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B.

Kisspeptin neurons in the ovine arcuate nucleus and preoptic area are involved in the preovulatory luteinizing hormone surge.

Kisspeptin signaling is required for the luteinizing hormone response in anestrous ewes following the introduction of males

Kisspeptin signalling in the brain: steroid regulation in the rodent and ewe.

Kisspeptin synchronizes preovulatory surges in cyclical ewes and causes ovulation in seasonally acyclic ewes

Leptin distribution and metabolism in the pregnant rat: transplacental leptin passage increases in late gestation but is reduced by excess glucocorticoids

Leptin receptor expression in the rat placenta: changes in ob-ra, ob-rb, and ob-re with gestational age and suppression by glucocorticoids

Maternal vitamin D deficiency alters fetal brain development in the BALB/c mouse

Neonatal overfeeding induces early decline of the ovarian reserve: Implications for the role of leptin.

Ontogeny of clock and KiSS-1 metastasis-suppressor (Kiss1) gene expression in the prepubertal mouse hypothalamus.

Placental and fetal growth retardation following partial progesterone withdrawal in rat pregnancy.

Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion

Pregnancy-induced adaptations of the central circadian clock and maternal glucocorticoids

Preweaning over- and underfeeding alters onset of puberty in the rat without affecting kisspeptin.

Regulation of Kiss1 gene expression in the brain of the female mouse.

Regulation of the neuroendocrine reproductive axis by kisspeptin-GPR54 signaling.

Seasonal and cyclical change in the luteinizing hormone response to kisspeptin in the ewe.

Sex steroid control of hypothalamic Kiss1 expression in sheep and rodents: comparative aspects.

Sex steroid regulation of kisspeptin circuits.

Unaltered Hypothalamic Metabolic Gene Expression in Kiss1r Knockout Mice Despite Obesity and Reduced Energy Expenditure