List of works - Chao Xu

A Radioactivity-Based Assay for Screening Human m6A-RNA Methyltransferase, METTL3-METTL14 Complex, and Demethylase ALKBH5

scientific article published on 23 December 2015

A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response

scientific journal article

A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR

scientific journal article

A telomerase subunit homolog La protein from Trypanosoma brucei plays an essential role in ribosomal biogenesis.

scientific article published in August 2019

Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8

scientific article

Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2)

scientific article

Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins.

scientific article

Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3

scientific article

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

scientific article published on 16 December 2017

Epigenetic targets and drug discovery: part 1: histone methylation.

scientific article published on 02 April 2014

First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.

scientific article published in September 2017

Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis

scientific article published on 06 June 2019

Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi

scientific article

NMR structure and regulated expression in APL cell of human SH3BGRL3.

scientific article

PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3

scientific article

Publisher Correction: Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis

scientific article published on 01 September 2019

Pup, a prokaryotic ubiquitin-like protein, is an intrinsically disordered protein.

scientific article

RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation

scientific article

Recognition of hyperacetylated N-terminus of H2AZ by TbBDF2 from Trypanosoma brucei

scientific article

Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock

scientific article

Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4

scientific article

Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.

scientific article

Solution structure of Rap1 BRCT domain from Saccharomyces cerevisiae reveals a novel fold

scientific article

Solution structure of TbTFIIS2-2 PWWP domain from and its binding to H4K17me3 and H3K32me3

scientific article published on 31 January 2019

Solution structure of Urm1 from Trypanosoma brucei

scientific article

Solution structure of human Brg1 bromodomain and its specific binding to acetylated histone tails

scientific article

Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP

scientific article

Solution structure of the Taf14 YEATS domain and its roles in cell growth of Saccharomyces cerevisiae.

scientific article published in May 2011

Solution structure of the first SH3 domain of human vinexin and its interaction with vinculin peptides

scientific article

Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins

scientific article

Structural Basis for the Recognition of Methylated Histone H3K36 by the Eaf3 Subunit of Histone Deacetylase Complex Rpd3S

scientific article

Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2

scientific article

Structural and Histone Binding Ability Characterizations of Human PWWP Domains

scientific article

Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain

scientific article

Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain

scientific article

Structural basis for the recognition of RFX7 by ANKRA2 and RFXANK

scientific article published on 19 December 2019

Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins.

scientific article published on 28 November 2017

Structural insight into the unique dsDNA binding topology of the human ORC2 wing helix domain

scientific article published on 19 April 2019

Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly

scientific journal article

Structural insights into SETD3-mediated histidine methylation on β-actin

scientific article published on 20 February 2019

Structure and function of WD40 domain proteins

scientific article

Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation

scientific article

Structure of a Second BRCT Domain Identified in the Nijmegen Breakage Syndrome Protein Nbs1 and its Function in an MDC1-Dependent Localization of Nbs1 to DNA Damage Sites

scientific article

Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-stranded N 6 -Methyladenosine RNA Demethylation

scientific article

Tudor domains of the PRC2 components PHF1 and PHF19 selectively bind to histone H3K36me3

scientific article published on 07 December 2012

YTH Domain: A Family of N-methyladenosine (mA) Readers

scientific article published on 30 April 2018

List of works by Chao Xu

A Radioactivity-Based Assay for Screening Human m6A-RNA Methyltransferase, METTL3-METTL14 Complex, and Demethylase ALKBH5

A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response

A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR

A telomerase subunit homolog La protein from Trypanosoma brucei plays an essential role in ribosomal biogenesis.

Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8

Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2)

Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins.

Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

Epigenetic targets and drug discovery: part 1: histone methylation.

First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.

Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis

Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi

NMR structure and regulated expression in APL cell of human SH3BGRL3.

PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3

Publisher Correction: Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis

Pup, a prokaryotic ubiquitin-like protein, is an intrinsically disordered protein.

RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation

Recognition of hyperacetylated N-terminus of H2AZ by TbBDF2 from Trypanosoma brucei

Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock

Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4

Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.

Solution structure of Rap1 BRCT domain from Saccharomyces cerevisiae reveals a novel fold

Solution structure of TbTFIIS2-2 PWWP domain from and its binding to H4K17me3 and H3K32me3

Solution structure of Urm1 from Trypanosoma brucei

Solution structure of human Brg1 bromodomain and its specific binding to acetylated histone tails

Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP

Solution structure of the Taf14 YEATS domain and its roles in cell growth of Saccharomyces cerevisiae.

Solution structure of the first SH3 domain of human vinexin and its interaction with vinculin peptides

Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins

Structural Basis for the Recognition of Methylated Histone H3K36 by the Eaf3 Subunit of Histone Deacetylase Complex Rpd3S

Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2

Structural and Histone Binding Ability Characterizations of Human PWWP Domains

Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain

Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain

Structural basis for the recognition of RFX7 by ANKRA2 and RFXANK

Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins.

Structural insight into the unique dsDNA binding topology of the human ORC2 wing helix domain

Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly

Structural insights into SETD3-mediated histidine methylation on β-actin

Structure and function of WD40 domain proteins

Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation

Structure of a Second BRCT Domain Identified in the Nijmegen Breakage Syndrome Protein Nbs1 and its Function in an MDC1-Dependent Localization of Nbs1 to DNA Damage Sites

Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-stranded N 6 -Methyladenosine RNA Demethylation

Tudor domains of the PRC2 components PHF1 and PHF19 selectively bind to histone H3K36me3

YTH Domain: A Family of N-methyladenosine (mA) Readers