List of works by Judith Klumperman

A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells

scientific article

A novel type of macrothrombocytopenia associated with a defect in α2,3-sialylation

scientific article

A viral protein that blocks Arf1-mediated COP-I assembly by inhibiting the guanine nucleotide exchange factor GBF1.

scientific article published on August 2006

AP-3 and Rabip4' coordinately regulate spatial distribution of lysosomes

scientific article

ATPase-deficient hVPS4 impairs formation of internal endosomal vesicles and stabilizes bilayered clathrin coats on endosomal vacuoles

scientific article

Aberrant receptor-mediated endocytosis of Schistosoma mansoni glycoproteins on host lipoproteins

scientific article (publication date: August 2006)

Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

scientific article published on October 2008

Anti-EGFL7 antibodies enhance stress-induced endothelial cell death and anti-VEGF efficacy

scientific article published on 15 August 2013

Apoptosis-linked gene-2 (ALG-2)/Sec31 interactions regulate endoplasmic reticulum (ER)-to-Golgi transport: a potential effector pathway for luminal calcium

scientific article

Architecture of the mammalian Golgi

scientific article published on July 2011

Atg5-independent sequestration of ubiquitinated mycobacteria

scientific article

Autophagy proteins regulate the secretory component of osteoclastic bone resorption

scientific article published on 4 November 2011

Autophagy, an Achilles' heel AKTing against cancer?

scientific article published on April 2009

Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes

scientific article

Cathepsin D and its newly identified transport receptor SEZ6L2 can modulate neurite outgrowth

scientific article published on 23 December 2015

Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity

scientific article

Correlative light-electron microscopy (CLEM) combining live-cell imaging and immunolabeling of ultrathin cryosections

scientific article

Cripto localizes Nodal at the limiting membrane of early endosomes

scientific article

Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation

scientific article

Death-receptor activation halts clathrin-dependent endocytosis

scholarly article

Discovery of Small Molecules That Induce Lysosomal Cell Death in Cancer Cell Lines Using an Image-Based Screening Platform

scientific article published on 22 September 2016

Disruption of the Man-6-P targeting pathway in mice impairs osteoclast secretory lysosome biogenesis

scientific article published on 5 May 2011

EGFL7 regulates the collective migration of endothelial cells by restricting their spatial distribution

scientific article

Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1

scientific journal article

Egfl7 knockdown causes defects in the extension and junctional arrangements of endothelial cells during zebrafish vasculogenesis

scientific article published on March 2008

Electron microscopy in cell biology: integrating structure and function

scientific article published on September 2003

Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin

scientific article

Endosomes are specialized platforms for bacterial sensing and NOD2 signalling

scientific article

Endosomes: multipurpose designs for integrating housekeeping and specialized tasks

scientific article

Glycolipid-dependent sorting of melanosomal from lysosomal membrane proteins by lumenal determinants

scientific article

Glycosylation Is Important for Cell Surface Expression of the Water Channel Aquaporin-2 but Is Not Essential for Tetramerization in the Endoplasmic Reticulum ⬇️

scientific article published on October 30, 2003

HC StratoMineR: A Web-Based Tool for the Rapid Analysis of High-Content Datasets

scientific article

Identification of the ubiquitin ligase Triad1 as a regulator of endosomal transport

scientific article published on 9 May 2012

Imaging and imagination: understanding the endo-lysosomal system

scientific article published on 15 February 2008

Intracellular activation of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus by nonpeptide agonists

scholarly article

Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure

scientific article published on 24 January 2007

Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins

scientific article

Loss of syntaxin 3 causes variant microvillus inclusion disease

scientific article

Lysosomal capturing of cytoplasmic injected nanoparticles by autophagy: an additional barrier to non viral gene delivery

scientific article published on 11 August 2014

Lysosomal membrane protein composition, acidic pH and sterol content are regulated via a light-dependent pathway in metazoan cells

scientific article published on 30 May 2011

Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis

scientific article

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

scientific article

Molecular Pathway of Microtubule Organization at the Golgi Apparatus

scientific article published on 17 September 2016

Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes

scientific journal article

Opinion: The maturing role of COPI vesicles in intra-Golgi transport

scientific article published in October 2005

Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway

scientific journal article

Presenilin-1 exists in both pre- and post-Golgi compartments and recycles via COPI-coated membranes

scientific article published on August 2003

R-SNARE ykt6 resides in membrane-associated protease-resistant protein particles and modulates cell cycle progression when over-expressed

scientific journal article

Rab14 is involved in membrane trafficking between the Golgi complex and endosomes

scientific article

Rab4 function in membrane recycling from early endosomes depends on a membrane to cytoplasm cycle

scientific article

Rabaptin-5alpha/rabaptin-4 serves as a linker between rab4 and gamma(1)-adaptin in membrane recycling from endosomes

scientific article

Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling

scientific article published on 25 July 2013

Rescue of a nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutant by cell-penetrating peptides

scientific article published on 8 May 2007

SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors

scientific article

Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel

scientific article (publication date: 28 November 2006)

Sorting nexin 17 facilitates LRP recycling in the early endosome

scientific article

Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides

scientific article

Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transport

scientific article

Spatial regulation of Golgi phosphatidylinositol-4-phosphate is required for enzyme localization and glycosylation fidelity

scientific article published on 21 June 2010

Sunday Driver links axonal transport to damage signaling

scientific article

Sunitinib and SU11652 inhibit acid sphingomyelinase, destabilize lysosomes, and inhibit multidrug resistance

scientific article

TGN exit of the cation-independent mannose 6-phosphate receptor does not require acid hydrolase binding

scientific article

Termination of autophagy and reformation of lysosomes regulated by mTOR

scientific article

The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion

scientific article

The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN)

scientific article

The UIM domain of Hrs couples receptor sorting to vesicle formation

scientific article published on 2 September 2003

The complex ultrastructure of the endolysosomal system.

scientific article

The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing

scientific article

The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM

scientific article

The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders

scientific article

Trafficking and function of the tetraspanin CD63.

scientific article published on 07 October 2008

Ultrastructural Characterization of Membrane Rearrangements Induced by Porcine Epidemic Diarrhea Virus Infection

scientific article published on 5 September 2017

Vacuolization of mucolipidosis type II mouse exocrine gland cells represents accumulation of autolysosomes

scientific article published on 16 February 2011

hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins

scientific article

mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles

scientific article published on 05 August 2009

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