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List of works by Loretta Dorstyn

A biochemical analysis of the activation of the Drosophila caspase DRONC.

scientific article

A cytochrome c-free fly apoptosome

scientific article published on 07 April 2006

A tumor suppressor function for caspase-2

scholarly article

Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice

scientific article

An essential role for the caspase dronc in developmentally programmed cell death in Drosophila

scientific article published in December 2000

An unexpected role for caspase-2 in neuroblastoma.

scientific article published on 21 August 2014

Analysing caspase activation and caspase activity in apoptotic cells.

scientific article published in January 2009

Caspase-2 as a tumour suppressor

scientific article

Caspase-2 deficiency accelerates chemically induced liver cancer in mice

scientific article published on 12 August 2016

Caspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity

scientific article

Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability

scientific article

Caspase-2 is required for cell death induced by cytoskeletal disruption

scientific article

Caspase-2 protects against oxidative stress in vivo

scientific article published on 22 December 2014

Caspase-2 protocols

scientific article published on January 2014

Caspase-2-mediated cell death is required for deleting aneuploid cells

scientific article

Characterization of the Drosophila caspase, DAMM.

scientific article published on 3 May 2001

DECAY, a novel Drosophila caspase related to mammalian caspase-3 and caspase-7.

scientific article published in October 1999

DRONC, an ecdysone-inducible Drosophila caspase

scientific article

Differential inhibitory effects of CrmA, P35, IAP and three mammalian IAP homologues on apoptosis in NIH3T3 cells following various death stimuli

scientific article published on 01 October 1997

Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons

scientific article

ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis.

scientific article published on 29 November 2013

Fat, sex and caspase-2.

scientific article published on 3 March 2016

Genetic background and tumour susceptibility in mouse models

scientific article published on 26 April 2013

Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice

scientific article

Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice

scientific article published on December 2016

Insect Caspases

scholarly article published 2013

Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice.

scientific article

Molecular determinants of the subcellular localization of the Drosophila Bcl-2 homologues DEBCL and BUFFY.

scientific article published on 5 January 2007

Ndfip1-deficient mice have impaired DMT1 regulation and iron homeostasis

scientific article published on 19 October 2010

New insights into apoptosome structure and function

scientific article published on 15 May 2018

Old, new and emerging functions of caspases

scientific article

Putative functions of caspase-2 ⬇️

scientific article published on December 15, 2009

Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2

scientific article

Structure of the Drosophila Apoptosome at 6.9 Å Resolution

scientific article

The role of cytochrome c in caspase activation in Drosophila melanogaster cells

scientific article

The tumor-modulatory effects of Caspase-2 and Pidd1 do not require the scaffold protein Raidd

scientific article

The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells

scientific article

Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling

scientific article published on 22 January 2019

Tumour necrosis factor alpha (TNF- ) stimulation of cells with established dengue virus type 2 infection induces cell death that is accompanied by a reduced ability of TNF- to activate nuclear factor B and reduced sphingosine kinase-1 activity

scientific article published on 09 December 2010

p53 accumulation following cytokinesis failure in the absence of caspase-2

scholarly article by Yoon Lim published in November 2018

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