List of works - Anne-Marie Cleton-Jansen

A distinct phenotype characterizes tumors from a putative genetic trait involving chondrosarcoma and breast cancer occurring in the same patient

scientific article published on February 2004

A murine mesenchymal stem cell model for initiating events in osteosarcomagenesis points to CDK4/CDK6 inhibition as a therapeutic target

scientific article published on 17 December 2021

A researcher's perspective on the quantity of osteosarcoma in vitro studies

scientific article

ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism

scientific article

Aberrant heparan sulfate proteoglycan localization, despite normal exostosin, in central chondrosarcoma

scientific article published on 29 January 2009

Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells

scientific article

BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors

scientific article

Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer

scientific article

CBFA2T3 (MTG16) is a putative breast tumor suppressor gene from the breast cancer loss of heterozygosity region at 16q24.3.

scientific article

Cellular/intramuscular myxoma and grade I myxofibrosarcoma are characterized by distinct genetic alterations and specific composition of their extracellular matrix

scientific article published on 13 March 2009

Central chondrosarcoma progression is associated with pRb pathway alterations: CDK4 down-regulation and p16 overexpression inhibit cell growth in vitro

scientific article published on 27 June 2008

E-cadherin and loss of heterozygosity at chromosome 16 in breast carcinogenesis: different genetic pathways in ductal and lobular breast cancer?

scientific article

Emerging pathways in the development of chondrosarcoma of bone and implications for targeted treatment

scientific article

Estrogen signaling is active in cartilaginous tumors: implications for antiestrogen therapy as treatment option of metastasized or irresectable chondrosarcoma

scientific article published on November 2005

Evaluation of high-resolution microarray platforms for genomic profiling of bone tumours

scientific article

Expression analysis of candidate breast tumour suppressor genes on chromosome 16q

scientific article

Expression of aromatase and estrogen receptor alpha in chondrosarcoma, but no beneficial effect of inhibiting estrogen signaling both in vitro and in vivo

scientific article

FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex

scientific article

Functional allelic loss detected at the protein level in archival human tumours using allele-specific E-cadherin monoclonal antibodies

scientific article published on August 2002

Functional characterization of osteosarcoma cell lines provides representative models to study the human disease

scientific article published on 25 April 2011

Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4 ⬇️

scientific article published on July 28, 2010

Hypoxia-related microRNA-210 is a diagnostic marker for discriminating osteoblastoma and osteosarcoma

scientific article published on 21 June 2016

IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications in central chondrosarcomas

scientific article published on 4 May 2017

IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma

scientific article

Immunotherapy: Is it different for sarcomas?

scientific article

Increased PD-L1 and T-cell infiltration in the presence of HLA class I expression in metastatic high-grade osteosarcoma: a rationale for T-cell-based immunotherapy

scientific article

Increased Risk of Breast Cancer at a Young Age in Women with Fibrous Dysplasia

scientific article published on 30 August 2017

Increased infiltration of M2-macrophages, T-cells and PD-L1 expression in high grade leiomyosarcomas supports immunotherapeutic strategies

scientific article published on 26 October 2017

Inhibition of Bcl-2 family members sensitizes mesenchymal chondrosarcoma to conventional chemotherapy: report on a novel mesenchymal chondrosarcoma cell line

scientific article published on 12 September 2016

Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma

scientific article

MLPAinter for MLPA interpretation: an integrated approach for the analysis, visualisation and data management of Multiplex Ligation-dependent Probe Amplification ⬇️

scientific article

Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with interferon-γ.

scientific article published on 10 March 2014

Mediator complex subunit 12 exon 2 mutation analysis in different subtypes of smooth muscle tumors confirms genetic heterogeneity

scientific article published on 19 March 2013

Mesenchymal stem cell transformation and sarcoma genesis ⬇️

scientific article published on July 23, 2013

MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma

scientific article published on 11 January 2013

Modulation of the osteosarcoma expression phenotype by microRNAs

scientific article

Molecular Analysis of Gene Fusions in Bone and Soft Tissue Tumors by Anchored Multiplex PCR–Based Targeted Next-Generation Sequencing

article

Molecular Pathology of Bone Tumors

scientific article published on 18 December 2018

Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort

scientific article published on January 2010

Molecular genetic evidence for monoclonal origin of bilateral ovarian serous borderline tumors

scientific article published on April 2003

Osteosarcoma models: from cell lines to zebrafish

scientific article published on 15 March 2012

Recurrent chromosome 22 deletions in osteoblastoma affect inhibitors of the Wnt/beta-catenin signaling pathway

scientific article

Sensitive and specific KRAS somatic mutation analysis on whole-genome amplified DNA from archival tissues

scientific article published on 03 December 2009

Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome

scientific article

Targeting JNK-interacting protein 1 (JIP1) sensitises osteosarcoma to doxorubicin ⬇️

scientific article published on October 1, 2012

Testing association of a pathway with survival using gene expression data

scientific article

The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report

scientific article published on 16 March 2016

The oncometabolite D-2-hydroxyglutarate induced by mutant IDH1 or -2 blocks osteoblast differentiation in vitro and in vivo

scientific article

Therapy-induced Enrichment of Cancer Stem-like Cells in Solid Human Tumors: Where do we stand?

scholarly article by Sara R. Martins-Neves et al published November 2018 in Pharmacological Research

Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity

scientific article (publication date: 2002)

Tumor-infiltrating macrophages are associated with metastasis suppression in high-grade osteosarcoma: a rationale for treatment with macrophage activating agents

scientific article published on 3 March 2011

Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma

scientific article published on 26 August 2013

Visualization of regional gene expression biases by microarray data sorting

scientific article

mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts

scientific article

List of works by Anne-Marie Cleton-Jansen

A distinct phenotype characterizes tumors from a putative genetic trait involving chondrosarcoma and breast cancer occurring in the same patient

A murine mesenchymal stem cell model for initiating events in osteosarcomagenesis points to CDK4/CDK6 inhibition as a therapeutic target

A researcher's perspective on the quantity of osteosarcoma in vitro studies

ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism

Aberrant heparan sulfate proteoglycan localization, despite normal exostosin, in central chondrosarcoma

Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells

BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors

Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer

CBFA2T3 (MTG16) is a putative breast tumor suppressor gene from the breast cancer loss of heterozygosity region at 16q24.3.

Cellular/intramuscular myxoma and grade I myxofibrosarcoma are characterized by distinct genetic alterations and specific composition of their extracellular matrix

Central chondrosarcoma progression is associated with pRb pathway alterations: CDK4 down-regulation and p16 overexpression inhibit cell growth in vitro

E-cadherin and loss of heterozygosity at chromosome 16 in breast carcinogenesis: different genetic pathways in ductal and lobular breast cancer?

Emerging pathways in the development of chondrosarcoma of bone and implications for targeted treatment

Estrogen signaling is active in cartilaginous tumors: implications for antiestrogen therapy as treatment option of metastasized or irresectable chondrosarcoma

Evaluation of high-resolution microarray platforms for genomic profiling of bone tumours

Expression analysis of candidate breast tumour suppressor genes on chromosome 16q

Expression of aromatase and estrogen receptor alpha in chondrosarcoma, but no beneficial effect of inhibiting estrogen signaling both in vitro and in vivo

FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex

Functional allelic loss detected at the protein level in archival human tumours using allele-specific E-cadherin monoclonal antibodies

Functional characterization of osteosarcoma cell lines provides representative models to study the human disease

Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4 ⬇️

Hypoxia-related microRNA-210 is a diagnostic marker for discriminating osteoblastoma and osteosarcoma

IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications in central chondrosarcomas

IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma

Immunotherapy: Is it different for sarcomas?

Increased PD-L1 and T-cell infiltration in the presence of HLA class I expression in metastatic high-grade osteosarcoma: a rationale for T-cell-based immunotherapy

Increased Risk of Breast Cancer at a Young Age in Women with Fibrous Dysplasia

Increased infiltration of M2-macrophages, T-cells and PD-L1 expression in high grade leiomyosarcomas supports immunotherapeutic strategies

Inhibition of Bcl-2 family members sensitizes mesenchymal chondrosarcoma to conventional chemotherapy: report on a novel mesenchymal chondrosarcoma cell line

Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma

MLPAinter for MLPA interpretation: an integrated approach for the analysis, visualisation and data management of Multiplex Ligation-dependent Probe Amplification ⬇️

Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with interferon-γ.

Mediator complex subunit 12 exon 2 mutation analysis in different subtypes of smooth muscle tumors confirms genetic heterogeneity

Mesenchymal stem cell transformation and sarcoma genesis ⬇️

MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma

Modulation of the osteosarcoma expression phenotype by microRNAs

Molecular Analysis of Gene Fusions in Bone and Soft Tissue Tumors by Anchored Multiplex PCR–Based Targeted Next-Generation Sequencing

Molecular Pathology of Bone Tumors

Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort

Molecular genetic evidence for monoclonal origin of bilateral ovarian serous borderline tumors

Osteosarcoma models: from cell lines to zebrafish

Recurrent chromosome 22 deletions in osteoblastoma affect inhibitors of the Wnt/beta-catenin signaling pathway

Sensitive and specific KRAS somatic mutation analysis on whole-genome amplified DNA from archival tissues

Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome

Targeting JNK-interacting protein 1 (JIP1) sensitises osteosarcoma to doxorubicin ⬇️

Testing association of a pathway with survival using gene expression data

The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report

The oncometabolite D-2-hydroxyglutarate induced by mutant IDH1 or -2 blocks osteoblast differentiation in vitro and in vivo

Therapy-induced Enrichment of Cancer Stem-like Cells in Solid Human Tumors: Where do we stand?

Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity

Tumor-infiltrating macrophages are associated with metastasis suppression in high-grade osteosarcoma: a rationale for treatment with macrophage activating agents

Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma

Visualization of regional gene expression biases by microarray data sorting

mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts