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List of works by David Keeling

A case of fatal pulmonary embolism raising questions about the dosing regimen for dalteparin in the very obese.

scientific article published on 5 May 2008

A family with type 2M VWD with normal VWF:RCo but reduced VWF:CB and a M1761K mutation in the A3 domain.

scientific article published on 17 October 2011

A practical guideline for the haematological management of major haemorrhage

scientific article published on 6 July 2015

A prospective registry of European haemophilia B patients receiving nonacog alfa, recombinant human factor IX, for usual use.

scientific article published on 2 November 2011

A raised beta 2-glycoprotein I level does not prolong the DRVVT

scientific article published on 01 August 1992

A simplified statistical method for local INR using linear regression

scientific article published on 01 December 1997

A single dose of Low-molecular-weight Heparin (LMWH) invalidates the use of D-dimer as part of a Deep Vein Thrombosis (DVT) diagnostic algorithm.

scientific article published on 15 December 2016

Achievement of immune tolerance in a patient with haemophilia B and inhibitory antibodies, complicated by an anaphylactoid reaction.

scientific article published in May 2007

Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation.

scientific article published on 17 October 2006

Activated prothrombin complex concentrate for the prevention of dabigatran-associated bleeding

scientific article published on 12 March 2014

Ala-10 mutations in the factor IX propeptide and haemorrhage in a patient treated with warfarin

scientific article published on 01 March 2000

An investigation of the von Willebrand factor genotype in UK patients diagnosed to have type 1 von Willebrand disease

scientific article published on 01 November 2006

Anti-DNA antibodies in the primary antiphospholipid syndrome (PAPS)

scientific article published on 01 May 1993

Audit of anticoagulation after embolectomy for acute ischaemia.

scientific article published on 25 June 2009

Changing patterns of bleeding in patients with severe haemophilia A.

scientific article published on 29 July 2009

Combined oral contraceptives and the risk of myocardial infarction.

scientific article published on January 2003

Comparison of a point of care device against current laboratory methodology using citrated and EDTA samples for the determination of D-dimers in the exclusion of proximal deep vein thrombosis.

scientific article published on 9 February 2010

Comparison of an immuno-turbidometric method (STalia D-DI) with an established enzyme linked fluorescent assay (VIDAS) D-dimer for the exclusion of venous thromboembolism.

scientific article

Controversies in venous thromboembolism--2015.

scientific article published on 17 July 2015

Cryoprecipitate prepared from plasma virally inactivated by the solvent detergent method

scientific article published on 01 January 1997

D-dimer for the exclusion of venous thromboembolism: comparison of a new automated latex particle immunoassay (MDA D-dimer) with an established enzyme-linked fluorescent assay (VIDAS D-dimer)

scientific article published on 01 October 1999

D-dimer test for excluding the diagnosis of pulmonary embolism

scientific article (publication date: 5 August 2016)

Diagnosis and management of heritable thrombophilias.

scientific article published on 17 July 2014

Diagnostic importance of the two-stage factor VIII:C assay demonstrated by a case of mild haemophilia associated with His1954-->Leu substitution in the factor VIII A3 domain.

scientific article published in June 1999

Duration of anticoagulation: decision making based on absolute risk.

scientific article

Effect of age on factor IX levels in symptomatic carriers of Haemophila B Leyden.

scientific article published on 10 November 2014

Efficacy of warfarin reversal in orthopedic trauma surgery patients.

scientific article published in January 2007

Evaluation of the von Willebrand factor antigen (vWF-Ag) assay using an immuno-turbidimetric method (STA Liatest vWF) automated on the MDA 180 coagulometer.

scientific article published in February 2000

Factor V Leiden haplotypes in two homozygotes of Asian origin.

scientific article

Factor VIII assays in haemophilia a patients treated with ReFacto.

scientific article published in April 2003

Factor X deficiency associated with compound heterozygosity involving a novel missense mutation at codon 38 from Val (GTC) to Leu (CTC) in exon 2.

scientific article published in April 2015

Fatal thromboembolism in acute promyelocytic leukaemia treated with a combination of all-trans retinoic acid and aprotonin.

scientific article published on March 1996

Genetic predisposition to bleeding during oral anticoagulant therapy: evidence for common founder mutations (FIXVal-10 and FIXThr-10) and an independent CpG hotspot mutation (FIXThr-10)

scientific article published on 01 March 2001

Guideline on aspects of cancer-related venous thrombosis

scientific article published on 26 June 2015

Guideline on the selection and use of therapeutic products to treat haemophilia and other hereditary bleeding disorders. A United Kingdom Haemophilia Center Doctors' Organisation (UKHCDO) guideline approved by the British Committee for Standards in

scientific article published on 04 April 2008

Guidelines on the diagnosis and management of heparin-induced thrombocytopenia: second edition.

scientific article

Guidelines on the investigation and management of venous thrombosis at unusual sites

scientific article published on 09 August 2012

Haematological manifestations of systemic lupus erythematosus.

scientific article

Haemolytic uraemic syndrome after bone marrow transplantation: an adverse effect of total body irradiation?

scientific article

Have You Been HIT?

scientific article

Heparin pretreatment does not alter heparin requirements during cardiopulmonary bypass.

scientific article

Hormone replacement therapy, thrombosis and thrombophilia

scientific article published on 01 June 2005

Idarucizumab for dabigatran overdose in a child

scientific article published on 13 October 2016

Inherited coagulation disorders

scientific article

International Normalized Ratio (INR) determination using calibrated reference plasmas.

scientific article published in December 1997

International Normalized Ratio in patients not on vitamin K antagonists.

scientific article published on 25 October 2006

Is there a benefit in computed tomography screening for cancer in patients with unprovoked proximal deep venous thrombosis? A cohort study in the Oxford University Hospitals NHS Trust

scientific article published on 11 June 2015

Management of bleeding in patients taking FXa and FIIa inhibitors.

scientific article

Management of muscle haematomas in patients with severe haemophilia in an evidence-poor world.

scientific article published on 12 December 2011

Management of von Willebrand disease: a guideline from the UK Haemophilia Centre Doctors' Organization.

scientific article published in May 2004

Managing antiplatelet and anticoagulant drugs in patients undergoing elective ophthalmic surgery

scientific article published on April 2014

Managing antiplatelet and anticoagulant drugs in patients undergoing elective ophthalmic surgery. Authors' response

scientific article published on 29 May 2014

Multiple transient ischaemic attacks and a mild thrombotic stroke in a HIV-positive patient with anticardiolipin antibodies.

scientific article published in August 1990

Myocardial infarction following recombinant activated factor VII in a patient with type 2A von Willebrand disease.

scientific article published in September 2004

Normal d-dimer levels do not exclude the diagnosis of cerebral venous sinus thrombosis

scientific article published on 01 November 2002

Optimal loading dose for the initiation of warfarin: a systematic review

scientific article

Optimal loading dose of warfarin for the initiation of oral anticoagulation

scientific article (publication date: 12 December 2012)

Patient self-testing and self-management of oral anticoagulation with vitamin K antagonists: guidance from the British Committee for Standards in Haematology

scientific article published on 21 August 2014

Peri-operative management of anticoagulation and antiplatelet therapy

scientific article published on 7 October 2016

Perioperative replacement therapy in haemophilia B: An appeal to “B” more precise

scientific article published on 29 April 2018

Plasma exchange as a source of protein C for acute-onset protein C pathway failure

scientific article published on 01 January 2003

Population pharmacokinetics of factor IX in hemophilia B patients undergoing surgery

scientific article published on 28 October 2018

Predicting the future: it's not a SNP.

scientific article published on 31 January 2008

Prevention of central venous catheter associated thrombosis using minidose warfarin in patients with haematological malignancies.

scientific article

Pulmonary embolus in Glanzmann's thrombasthenia treated with warfarin

scientific article

Rebuttal--a prospective controlled trial comparing weekly self-testing and self-dosing with the standard management of patients on stable oral anticoagulation

scientific article published on 01 November 2000

Reducing the need for diagnostic imaging in suspected cases of deep vein thrombosis

scientific article published on 02 April 2018

Relation between acute hypoxia and activation of coagulation in human beings

scientific article published in The Lancet

Rituximab and immune tolerance in severe hemophilia A: a consecutive national cohort.

scientific article

Role of beta 2-glycoprotein I and anti-phospholipid antibodies in activation of protein C in vitro

scientific article

Safety indicators for inpatient and outpatient oral anticoagulant care: [corrected] Recommendations from the British Committee for Standards in Haematology and National Patient Safety Agency

scientific article published on 20 November 2006

Sagittal sinus thrombosis in a teenager: homocystinuria associated with reversible antithrombin deficiency.

scientific article published in July 2002

Should we screen for factor V Leiden?

scientific article published on 01 January 1998

Some 'antiphospholipid antibodies' bind to beta 2-glycoprotein I in the absence of phospholipid

scientific article published on 01 November 1992

Stockings to prevent post-thrombotic syndrome-where are we now?

scientific article published in January 2018

The acute management of haemorrhage, surgery and overdose in patients receiving dabigatran.

scientific article published on 22 February 2013

The aspirin story - from willow to wonder drug.

scientific article published on 20 January 2017

The diagnosis and management of factor VIII and IX inhibitors: a guideline from the United Kingdom Haemophilia Centre Doctors Organisation.

scientific article

The diagnosis and management of von Willebrand disease: a United Kingdom Haemophilia Centre Doctors Organization guideline approved by the British Committee for Standards in Haematology

scientific article

The diagnosis of von Willebrand disease: a guideline from the UK Haemophilia Centre Doctors' Organization.

scientific article

The fibrinolytic response to venous occlusion and the natural anticoagulants in patients with antiphospholipid antibodies both with and without systemic lupus erythematosus

scientific article published on 01 March 1991

The incidence of factor VIII and factor IX inhibitors in the hemophilia population of the UK and their effect on subsequent mortality, 1977-99.

scientific article published in July 2004

The management of heparin-induced thrombocytopenia

scientific article published on 04 September 2006

The management of heparin-induced thrombocytopenia.

scientific article

The prevalence of the cysteine1584 variant of von Willebrand factor is increased in type 1 von Willebrand disease: co-segregation with increased susceptibility to ADAMTS13 proteolysis but not clinical phenotype.

scientific article

The use of age-dependent D-dimer cut-off values to exclude deep vein thrombosis. Reply to "Using an age-dependent D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can be safely excluded". Haematologica 2012;9

scientific article

The use of artificial neural network analysis can improve the risk-stratification of patients presenting with suspected deep vein thrombosis

scientific article published on 06 February 2019

The use of enhanced half-life coagulation factor concentrates in routine clinical practice: guidance from UKHCDO.

scientific article published on 16 June 2016

The use of rituximab in two children with allo-antibodies towards factor VIII.

scientific article published in April 2006

Treating alcohol dependence. One glass of wine is usually 1.5 units.

scientific article published on November 1997

Treatment related factors and inhibitor development in children with severe haemophilia A.

scientific article published on 11 November 2010

Treponemal infection coexisting with systemic lupus erythematosus

scientific article published on 01 May 1992

Unexpected haemophilia despite pre-natal testing - a combined haemophilia A and haemophilia B family.

scientific article published on 5 July 2017

Universal or selected screening for thrombophilia.

scientific article

Variation in inhibitor reactivity in acquired haemophilia A with different concentrates.

scientific article published in October 2000

Venous thromboembolism: risk of recurrence and long-term anticoagulation

scientific article published on 01 February 2015

Von Willebrand disease, angiodysplasia and atorvastatin.

scientific article published on 7 December 2009

von Willebrand disease and extra-intestinal angiodysplasia.

scientific article published on 2 June 2017

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