List of works by Guillermo Guenechea

A protocol describing the genetic correction of somatic human cells and subsequent generation of iPS cells.

scientific article published on 11 March 2010

AM218, a new polyanionic polysaccharide, induces radioprotection in mice when administered shortly before irradiation

scientific article published on 01 January 1997

Advances in the gene therapy of monogenic blood cell diseases

scientific article published on 24 June 2019

Brief report: impaired cell reprogramming in nonhomologous end joining deficient cells.

scientific article published in August 2013

Characteristics of lentiviral vectors harboring the proximal promoter of the vav proto-oncogene: a weak and efficient promoter for gene therapy

scientific article published on 29 May 2007

Conversion of human fibroblasts into monocyte-like progenitor cells

scientific article

DNA delivery to 'ex vivo' human liver segments.

scientific article published on 13 October 2011

Development of lentiviral vectors with optimized transcriptional activity for the gene therapy of patients with Fanconi anemia

scientific article published in May 2010

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells.

scientific article

Distinct classes of human stem cells that differ in proliferative and self-renewal potential

scientific article published in January 2001

Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors.

scientific article published on 31 January 2018

Engraftment and in vivo proliferation advantage of gene corrected mobilized CD34(+) cells from Fanconi anemia patients.

scientific article published on 11 August 2017

Ex vivo expansion of umbilical cord blood (UCB) CD34(+) cells alters the expression and function of alpha 4 beta 1 and alpha 5 beta 1 integrins

scientific article published on 01 October 2001

GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells

scientific article published on 22 January 2019

Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.

scientific article

Generation of iPSCs from genetically corrected Brca2 hypomorphic cells: implications in cell reprogramming and stem cell therapy

scientific article published in February 2014

Immunomagnetic enrichment of human and mouse hematopoietic stem cells for gene therapy applications

scientific article

In vivo proliferation advantage of genetically corrected hematopoietic stem cells in a mouse model of Fanconi anemia FA-D1.

scientific article published on 23 September 2008

Lentiviral vector integration sites in human NOD/SCID repopulating cells

scientific article published in October 2006

Lentiviral-Mediated Gene Therapy in Fanconi Anemia-A Mice Reveals Long-Term Engraftment and Continuous Turnover of Corrected HSCs.

scientific article published on 29 September 2015

Lentiviral-mediated genetic correction of hematopoietic and mesenchymal progenitor cells from Fanconi anemia patients

scientific article published on 10 March 2009

Molecular Evidence of Genome Editing in a Mouse Model of Immunodeficiency.

scientific article

Mutations in XLF/NHEJ1/Cernunnos gene results in downregulation of telomerase genes expression and telomere shortening

scientific article published on 24 March 2017

Optimization of lentiviral vectors for the gene therapy of fanconi anemia

article

Parvovirus infection suppresses long-term repopulating hematopoietic stem cells

scientific article

Preclinical gene therapy studies of fanconi anemia with lentiviral vectors

article

Preserved long-term repopulation and differentiation properties of hematopoietic grafts subjected to ex vivo expansion with stem cell factor and interleukin 11

scientific article published on 01 May 1999

Radioprotection mediated by the haemopoietic stimulation conferred by AM5: a protein-associated polysaccharide

scientific article published on 01 July 1992

Regulatory elements of the vav gene drive transgene expression in hematopoietic stem cells from adult mice

scientific article published in April 2004

Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia

scientific article published on 09 September 2019

Targeted gene therapy into a safe harbor site in human hematopoietic progenitor cells

scientific article published on 26 March 2020

The role of the vav promoter in gene therapy: Safer vectors with weaker and stable expression

article

Transduction of Human CD34+CD38- Bone Marrow and Cord Blood-Derived SCID-Repopulating Cells with Third-Generation Lentiviral Vectors

scientific article published on 01 June 2000

Unaltered repopulation properties of mouse hematopoietic stem cells transduced with lentiviral vectors.

scientific article published on 06 August 2008

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