List of works - Emilia Kansanen

Activation of stress signaling pathways by electrophilic oxidized and nitrated lipids ⬇️

scientific article published on December 13, 2011

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

scientific article

Dysregulation of the Keap1-Nrf2 pathway in cancer

scientific article published on 03 August 2015

Effect of temporin A modifications on its cytotoxicity and antimicrobial activity

scientific article published in July 2005

Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis

scientific article published on 22 November 2018

Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism

scientific article

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism

scientific article

Enterolactone induces heme oxygenase-1 expression through nuclear factor-E2-related factor 2 activation in endothelial cells.

scientific article

HIF-1α and HIF-2α induce angiogenesis and improve muscle energy recovery

scientific article published in October 2014

MicroRNA Profiling Reveals Distinct Profiles for Tissue-Derived and Cultured Endothelial Cells.

scientific article published on 8 September 2017

MicroRNAs mediate the senescence-associated decline of NRF2 in endothelial cells.

scientific article published on 22 June 2018

NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation

scientific article

Nitro-oleic acid regulates endothelin signaling in human endothelial cells.

scientific article published on 04 August 2017

Novel insights into the regulation of antioxidant-response-elementmediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2

article

Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.

scientific article

Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo

scientific article published on 25 January 2007

Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo

scientific article published on 5 June 2008

Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid

scientific article published on 05 October 2009

Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice

article

Oxidative stress-inducible lentiviral vectors for gene therapy.

scientific article published in May 2008

Oxidative stress-regulated lentiviral TK/GCV gene therapy for lung cancer treatment

scientific article

Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics.

scientific article

Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2.

scientific article published on 30 June 2009

Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL)

scientific article published on 19 August 2014

Role of the Keap1-Nrf2 pathway in cancer

scientific article published on January 2014

Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2.

scientific article published on 10 January 2008

Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells

scientific article published on 21 July 2010

The Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPs

scientific article

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

scientific article

The absence of macrophage Nrf2 promotes early atherogenesis

scientific article published on 22 January 2013

Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects

scientific article

List of works by Emilia Kansanen

Activation of stress signaling pathways by electrophilic oxidized and nitrated lipids ⬇️

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

Dysregulation of the Keap1-Nrf2 pathway in cancer

Effect of temporin A modifications on its cytotoxicity and antimicrobial activity

Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis

Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism

Enterolactone induces heme oxygenase-1 expression through nuclear factor-E2-related factor 2 activation in endothelial cells.

HIF-1α and HIF-2α induce angiogenesis and improve muscle energy recovery

MicroRNA Profiling Reveals Distinct Profiles for Tissue-Derived and Cultured Endothelial Cells.

MicroRNAs mediate the senescence-associated decline of NRF2 in endothelial cells.

NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation

Nitro-oleic acid regulates endothelin signaling in human endothelial cells.

Novel insights into the regulation of antioxidant-response-elementmediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2

Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.

Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo

Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo

Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid

Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice

Oxidative stress-inducible lentiviral vectors for gene therapy.

Oxidative stress-regulated lentiviral TK/GCV gene therapy for lung cancer treatment

Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics.

Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2.

Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL)

Role of the Keap1-Nrf2 pathway in cancer

Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2.

Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells

The Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPs

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

The absence of macrophage Nrf2 promotes early atherogenesis

Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects