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List of works by Robin J McAnulty

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Fibroblasts and myofibroblasts: their source, function and role in disease.

scientific article published on 23 November 2006
Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response.

scientific article published on October 2002
Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice

scientific article
Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome

scientific article published in September 2002
Angiotensin II and the fibroproliferative response to acute lung injury.

scientific article
Diminished prostaglandin E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis

scientific article
Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).

scientific article published on 15 January 2009
Direct thrombin inhibition reduces lung collagen, accumulation, and connective tissue growth factor mRNA levels in bleomycin-induced pulmonary fibrosis.

scientific article
Mast cell tryptase stimulates human lung fibroblast proliferation via protease-activated receptor-2

scientific article published on 01 January 2000
Fibroproliferation occurs early in the acute respiratory distress syndrome and impacts on outcome

scientific article published on 01 November 2000
Inverse effects of interleukin-6 on apoptosis of fibroblasts from pulmonary fibrosis and normal lungs

scientific article
Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1

scientific article
Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.

scientific article
Angiotensin II is mitogenic for human lung fibroblasts via activation of the type 1 receptor.

scientific article
Age-related changes in collagen synthesis and degradation in rat tissues. Importance of degradation of newly synthesized collagen in regulating collagen production.

scientific article published on June 1991
Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

scientific article
Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis

scientific article
TGF-beta: its role in asthma and therapeutic potential

scientific article
Role of thrombin in pulmonary fibrosis

scientific article published on 01 October 1995
Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF

scientific article published on 21 April 2016
Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts

scientific article
A simplified method for quantitation of the relative amounts of type I and type III collagen in small tissue samples

scientific article published on 01 May 1981
Collagen synthesis and degradation in vivo. Evidence for rapid rates of collagen turnover with extensive degradation of newly synthesized collagen in tissues of the adult rat

scientific article published on 01 June 1987
The pathogenesis of pulmonary fibrosis: is there a fibrosis gene?

scientific article published on January 1997
Tgf-Beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma

scientific article
Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.

scientific article published on 20 October 2017
Increased levels of endothelin-1 in bronchoalveolar lavage fluid from patients with systemic sclerosis contribute to fibroblast mitogenic activity in vitro

scientific article published on 01 October 1994
An integrin-targeted non-viral vector for pulmonary gene therapy

scientific article published in March 2000
Diverse cellular TGF-beta 1 and TGF-beta 3 gene expression in normal human and murine lung

scientific article published on 01 December 1996
Protein metabolism during bleomycin-induced pulmonary fibrosis in rabbits. In vivo evidence for collagen accumulation because of increased synthesis and decreased degradation of the newly synthesized collagen

scientific article published on 01 July 1983
The effect of transforming growth factor beta on rates of procollagen synthesis and degradation in vitro

scientific article published on 01 January 1991
A receptor-targeted nanocomplex vector system optimized for respiratory gene transfer

scientific article published on 25 March 2008
Insulin-like growth factor-I is partially responsible for fibroblast proliferation induced by bronchoalveolar lavage fluid from patients with systemic sclerosis

scientific article published on 01 February 1994
Regulation of matrix turnover: fibroblasts, forces, factors and fibrosis.

scientific article published on August 2007
Escape from the matrix: multiple mechanisms for fibroblast activation in pulmonary fibrosis

scientific article published in April 2008
Biochemical and histological changes in pulmonary fibrosis induced in rabbits with intratracheal bleomycin

scientific article published on 01 December 1981
Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling

scientific article
Increased endothelin-1 and its localization during the development of bleomycin-induced pulmonary fibrosis in rats

scientific article published on 01 May 1998
Application of high-pressure liquid chromatography to studies of collagen production by isolated cells in culture

scientific article published on 01 May 1990
Evaluation of a porcine model for pulmonary gene transfer using a novel synthetic vector

scientific article
Oral N-acetylcysteine reduces bleomycin-induced collagen deposition in the lungs of mice

scientific article published on 01 July 1991
Short course dexamethasone treatment following injury inhibits bleomycin induced fibrosis in rats.

scientific article published in September 2003
Characterization of murine pregnancy decidua transforming growth factor beta. I. Transforming growth factor beta 2-like molecules of unusual molecular size released in bioactive form

scientific article published in June 1995
Oxygen-dependent protection of radiation lung damage in mice by WR 2721

scientific article published on 01 November 1984
Enhanced type III collagen gene expression during bleomycin induced lung fibrosis.

scientific article
Effect of endothelin receptor antagonists (BQ-485, Ro 47-0203) on collagen deposition during the development of bleomycin-induced pulmonary fibrosis in rats

scientific article published on 01 April 1998
Attenuation of bleomycin induced pulmonary fibrosis in mice using the heme oxygenase inhibitor Zn-deuteroporphyrin IX-2,4-bisethylene glycol.

scientific article published on March 2004
Nebulisation of receptor-targeted nanocomplexes for gene delivery to the airway epithelium.

scientific article
Age-related changes in lung collagen metabolism. A role for degradation in regulating lung collagen production

scientific article published on 01 August 1989
Methods for measuring hydroxyproline and estimating in vivo rates of collagen synthesis and degradation

scientific article published in January 2005

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