List of works - Francesco Saladini

(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity

scientific article published on 21 February 2020

A novel methodology for large-scale phylogeny partition

scientific article published on 24 May 2011

Agreement between an in-house replication competent and a reference replication defective recombinant virus assay for measuring phenotypic resistance to HIV-1 protease, reverse transcriptase, and integrase inhibitors.

scientific article published on 17 March 2017

Changing patterns in HIV-1 non-B clade prevalence and diversity in Italy over three decades

scientific article

Comparable In Vitro Activities of Second-Generation HIV-1 Integrase Strand Transfer Inhibitors (INSTIs) on HIV-1 Clinical Isolates with INSTI Resistance Mutations

scientific article published on 20 December 2019

Comparative analysis of different cell systems for Zika virus (ZIKV) propagation and evaluation of anti-ZIKV compounds in vitro

scientific article published on 4 November 2017

Detection of residual human immunodeficiency virus type 1 reverse transcriptase K103N minority species in plasma RNA and peripheral blood mononuclear cell DNA following discontinuation of non-nucleoside therapy.

scientific article published on 21 July 2009

Development of an internally controlled quantitative PCR to measure total cell-associated HIV-1 DNA in blood

scientific article published on 15 September 2017

Discordances with HIV-1 RNA quantitative determinations by three commercial assays in Pointe Noire, Republic of Congo

scientific article published on 30 March 2014

Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-carboxylic Acids as Dual Bacterial RNA Polymerase and Viral Reverse Transcriptase Inhibitors

scientific article published on 24 June 2016

Evolution of transmitted HIV-1 drug resistance and viral subtypes circulation in Italy from 2006 to 2016

article

Feasibility and reproducibility of HIV-1 genotype resistance test in very-low-level viremia

scientific article published in December 2014

Frequent detection of antiretroviral drug resistance in HIV-1-infected orphaned children followed at a donor-funded rural pediatric clinic in Dodoma, Tanzania

scientific article published on 31 December 2014

HIV-1 A1 Subtype Epidemic in Italy Originated from Africa and Eastern Europe and Shows a High Frequency of Transmission Chains Involving Intravenous Drug Users

scientific article

Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents

scientific article published on 26 April 2016

Identification of a possible ancestor of the subtype A1 HIV Type 1 variant circulating in the former Soviet Union

scientific article published in October 2008

Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein

scientific article published on 24 December 2017

Impact of extensive HIV-1 variability on molecular diagnosis in the Congo basin

scientific article published on 20 February 2010

Impact of remote versus local sampling on sensitivity of genotypic antiretroviral resistance testing

scientific article published on 21 April 2010

Impact of the M184V Resistance Mutation on Virological Efficacy and Durability of Lamivudine-Based Dual Antiretroviral Regimens as Maintenance Therapy in Individuals With Suppressed HIV-1 RNA: A Cohort Study.

scientific article

Low-cost simultaneous detection of CCR5-delta32 and HLA-B*5701 alleles in human immunodeficiency virus type 1 infected patients by selective multiplex endpoint PCR.

scientific article published on 2 September 2015

Natural NS5A inhibitor Resistance Associated Substitutions in HCV genotype 1 infected patients from Italy

scientific article published on 12 August 2017

Natural variability in the HR-1 and HR-2 domains of HIV type 1 gp41 from different clades circulating in Italy

scientific article published on April 2007

Naturally occurring hepatitis C virus (HCV) NS3/4A protease inhibitor resistance-related mutations in HCV genotype 1-infected subjects in Italy

scientific article published on 18 January 2012

Near full-length sequence analysis of HIV type 1 BF recombinants from Italy

scientific article published on 8 July 2011

Prevalence of HIV-1 Subtypes and Drug Resistance-Associated Mutations in HIV-1-Positive Treatment-Naive Pregnant Women in Pointe Noire, Republic of the Congo (Kento-Mwana Project).

scientific article published on 2 June 2015

Prevalence of HIV-1 integrase mutations related to resistance to dolutegravir in raltegravir naïve and pretreated patients.

scientific article

Recombination analysis and structure prediction show correlation between breakpoint clusters and RNA hairpins in the pol gene of human immunodeficiency virus type 1 unique recombinant forms

scientific article published in December 2008

Role of phenotypic investigation in the era of routine genotypic HIV-1 drug resistance testing

article

Stability of unfrozen whole blood DNA for remote genotypic analysis of HIV-1 coreceptor tropism

scientific article

Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains.

scientific article published on 13 December 2017

Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X

scientific article published on 04 November 2019

Synthesis and Evaluation of Bifunctional Aminothiazoles as Antiretrovirals Targeting the HIV-1 Nucleocapsid Protein

article

The HIV-1 integrase E157Q polymorphism per se does not alter susceptibility to raltegravir and dolutegravir in vitro

scientific article

The HIV-1 reverse transcriptase E138A natural polymorphism decreases the genetic barrier to resistance to etravirine in vitro

article

Three-class-resistant human immunodeficiency virus type 1 variant in a drug-naive heterosexual couple

scientific article published on 24 September 2008

Two Distinct Hepatitis C Virus Genotype 1a Clades Have Different Geographical Distribution and Association With Natural Resistance to NS3 Protease Inhibitors

scientific article published on 31 March 2015

Use of peripheral blood DNA for genotype antiretroviral resistance testing in drug-naive HIV-infected subjects

scientific article published on 8 May 2007

List of works by Francesco Saladini

(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity

A novel methodology for large-scale phylogeny partition

Agreement between an in-house replication competent and a reference replication defective recombinant virus assay for measuring phenotypic resistance to HIV-1 protease, reverse transcriptase, and integrase inhibitors.

Changing patterns in HIV-1 non-B clade prevalence and diversity in Italy over three decades

Comparable In Vitro Activities of Second-Generation HIV-1 Integrase Strand Transfer Inhibitors (INSTIs) on HIV-1 Clinical Isolates with INSTI Resistance Mutations

Comparative analysis of different cell systems for Zika virus (ZIKV) propagation and evaluation of anti-ZIKV compounds in vitro

Detection of residual human immunodeficiency virus type 1 reverse transcriptase K103N minority species in plasma RNA and peripheral blood mononuclear cell DNA following discontinuation of non-nucleoside therapy.

Development of an internally controlled quantitative PCR to measure total cell-associated HIV-1 DNA in blood

Discordances with HIV-1 RNA quantitative determinations by three commercial assays in Pointe Noire, Republic of Congo

Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-carboxylic Acids as Dual Bacterial RNA Polymerase and Viral Reverse Transcriptase Inhibitors

Evolution of transmitted HIV-1 drug resistance and viral subtypes circulation in Italy from 2006 to 2016

Feasibility and reproducibility of HIV-1 genotype resistance test in very-low-level viremia

Frequent detection of antiretroviral drug resistance in HIV-1-infected orphaned children followed at a donor-funded rural pediatric clinic in Dodoma, Tanzania

HIV-1 A1 Subtype Epidemic in Italy Originated from Africa and Eastern Europe and Shows a High Frequency of Transmission Chains Involving Intravenous Drug Users

Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents

Identification of a possible ancestor of the subtype A1 HIV Type 1 variant circulating in the former Soviet Union

Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein

Impact of extensive HIV-1 variability on molecular diagnosis in the Congo basin

Impact of remote versus local sampling on sensitivity of genotypic antiretroviral resistance testing

Impact of the M184V Resistance Mutation on Virological Efficacy and Durability of Lamivudine-Based Dual Antiretroviral Regimens as Maintenance Therapy in Individuals With Suppressed HIV-1 RNA: A Cohort Study.

Low-cost simultaneous detection of CCR5-delta32 and HLA-B*5701 alleles in human immunodeficiency virus type 1 infected patients by selective multiplex endpoint PCR.

Natural NS5A inhibitor Resistance Associated Substitutions in HCV genotype 1 infected patients from Italy

Natural variability in the HR-1 and HR-2 domains of HIV type 1 gp41 from different clades circulating in Italy

Naturally occurring hepatitis C virus (HCV) NS3/4A protease inhibitor resistance-related mutations in HCV genotype 1-infected subjects in Italy

Near full-length sequence analysis of HIV type 1 BF recombinants from Italy

Prevalence of HIV-1 Subtypes and Drug Resistance-Associated Mutations in HIV-1-Positive Treatment-Naive Pregnant Women in Pointe Noire, Republic of the Congo (Kento-Mwana Project).

Prevalence of HIV-1 integrase mutations related to resistance to dolutegravir in raltegravir naïve and pretreated patients.

Recombination analysis and structure prediction show correlation between breakpoint clusters and RNA hairpins in the pol gene of human immunodeficiency virus type 1 unique recombinant forms

Role of phenotypic investigation in the era of routine genotypic HIV-1 drug resistance testing

Stability of unfrozen whole blood DNA for remote genotypic analysis of HIV-1 coreceptor tropism

Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains.

Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X

Synthesis and Evaluation of Bifunctional Aminothiazoles as Antiretrovirals Targeting the HIV-1 Nucleocapsid Protein

The HIV-1 integrase E157Q polymorphism per se does not alter susceptibility to raltegravir and dolutegravir in vitro

The HIV-1 reverse transcriptase E138A natural polymorphism decreases the genetic barrier to resistance to etravirine in vitro

Three-class-resistant human immunodeficiency virus type 1 variant in a drug-naive heterosexual couple

Two Distinct Hepatitis C Virus Genotype 1a Clades Have Different Geographical Distribution and Association With Natural Resistance to NS3 Protease Inhibitors

Use of peripheral blood DNA for genotype antiretroviral resistance testing in drug-naive HIV-infected subjects