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List of works by Wen-Chung Lee

A DNA pooling strategy for family-based association studies

scientific article published in April 2005

A Five-Region Hypothesis Test for Exposure-Disease Associations

scientific article

A Fuzzy Permutation Method for False Discovery Rate Control

scientific article published on 22 June 2016

A cross-ethnic comparison on incidence of suicide.

scientific article published on 22 September 2010

A multiple logistic regression analysis of risk factors in different subtypes of gastric ulcer

scientific article published on 01 March 2002

A partial SMR approach to smoothing age-specific rates

scientific article published on 01 February 2003

A permutation method to assess heterogeneity in external validation for risk prediction models

scientific article

A permutation test for oligoset DNA pooling studies

scientific article

A regression-based method for estimating risks and relative risks in case-base studies

scientific article

A scoring system for the early detection of oral submucous fibrosis based on a self-administered questionnaire

scientific article published in January 2002

A simple method to estimate prediction intervals and predictive distributions: Summarizing meta-analyses beyond means and confidence intervals

scientific article published on 05 March 2019

A triple combination strategy corrects population stratification bias and saves genotyping cost.

scientific article published on 13 November 2010

Additional therapeutic effects of electroacupuncture in conjunction with conventional rehabilitation for patients with first-ever ischaemic stroke

scientific article published in April 2007

Addressing the identification problem in age-period-cohort analysis: a tutorial on the use of partial least squares and principal components analysis.

scientific article published on July 2012

Admixture mapping using interval transmission/disequilibrium tests.

scientific article published in November 2003

Age-period-cohort analysis of motor vehicle mortality in Taiwan, 1974-1992.

scientific article published on September 1996

Age-period-cohort analysis with a constant-relative-variation constraint for an apportionment of period and cohort slopes

scientific article published on 19 December 2019

Age-standardized expected years of life lost: quantification of cancer severity

scientific article published on 02 May 2019

Alternative performance measures for prediction models

scientific article

An Online Atlas for Exploring Spatio-Temporal Patterns of Cancer Mortality (1972-2011) and Incidence (1995-2008) in Taiwan.

scientific article published on May 2016

An easy-to-implement approach for analyzing case-control and case-only studies assuming gene-environment independence and Hardy-Weinberg equilibrium.

scientific article published in October 2010

An evaluation of the 25 by 25 goal for premature cardiovascular disease mortality in Taiwan: an age-period-cohort analysis, population attributable fraction and national population-based study.

scientific article published on 7 August 2017

Are the effects of botulinum toxin injection on myofascial trigger points placebo effects or needling effects?

scientific article published on 01 April 2008

Assessing causal mechanistic interactions: a peril ratio index of synergy based on multiplicativity

scientific article

Assessing effects of disease genes and gene-environment interactions: the case-spouse design and the counterfactual-control analysis

scientific article published on August 2006

Associations between ambient air pollution and cancer incidence in Taiwan: an ecological study of geographical variations

scientific article published on 09 November 2019

Asthma and suicide mortality in young people: a 12-year follow-up study

scientific article published on 15 July 2010

Autoregressive age-period-cohort models

scientific article published in February 1996

Baseline human papillomavirus infection, high vaginal parity, and their interaction on cervical cancer risks after a follow-up of more than 10 years.

scientific article

Bounding formulas for selection bias.

scientific article published on 29 October 2015

Bounding the bias of unmeasured factors with confounding and effect-modifying potentials.

scientific article published on 13 January 2011

Case recruitment in genetic association studies: larger sample size or greater homogeneity?

scientific article published on 15 April 2005

Case-control association studies with matching and genomic controlling

scientific article published on 01 July 2004

Changes in serum levels of HBV DNA and alanine aminotransferase determine risk for hepatocellular carcinoma

scientific article published on 22 June 2011

Changing trends in the prevalence of common mental disorders in Taiwan: a 20-year repeated cross-sectional survey

scientific article published on 12 November 2012

Characteristics of young lung cancer: Analysis of Taiwan's nationwide lung cancer registry focusing on epidermal growth factor receptor mutation and smoking status

scientific article published on 13 May 2016

Characterizing Decision-Analysis Performances of Risk Prediction Models Using ADAPT Curves

scientific article

Characterizing exposure-disease association in human populations using the Lorenz curve and Gini index

scientific article published on 01 April 1997

Clinical effects of lateral wedge arch support insoles in knee osteoarthritis: A prospective double-blind randomized study.

scientific article published on July 2016

Clinicopathologic Characteristics of Helicobacter Pyloric Seropositive Gastric Adenocarcinomas

scientific article published on 01 October 1995

Combining TNFSF15 and ASCA IgA can be used as a predictor for the stenosis/perforating phenotype of Crohn's disease

scientific article

Complementary Log Regression for Sufficient-Cause Modeling of Epidemiologic Data

scientific article

Completion Potentials of Sufficient Component Causes ⬇️

scientific article published on May 1, 2012

Correction: Elevated Aspartate and Alanine Aminotransferase Levels and Natural Death among Patients with Methamphetamine Dependence.

scientific article published on 25 January 2012

Correlates of degree of nerve involvement in early Bell's palsy

scientific article

Correlation between the incidence and severity of Bell's palsy and seasonal variations in Taiwan.

scientific article

Correlations between functional performance, health-related quality of life, and parental impact on children with developmental delays

scientific article published on 8 October 2013

Data-dredging gene-dose analyses in association studies: biases and their corrections

scientific article published in December 2005

Decreasing rate of biliary atresia in Taiwan: a survey, 2004-2009.

scientific article published on 28 August 2011

Detecting a weak association by testing its multiple perturbations: a data mining approach

scientific article

Detecting and correcting the bias of unmeasured factors using perturbation analysis: a data-mining approach

scientific article

Detecting differentially expressed genes in heterogeneous diseases using control-only analysis of variance.

scientific article published on 31 May 2012

Detecting differentially expressed genes in heterogeneous diseases using half Student's t-test

scientific article

Detecting differentially expressed genes: minimizing burden of testing and maximizing number of discoveries

scientific article published on 26 June 2010

Detecting population stratification using a panel of single nucleotide polymorphisms

scientific article published on 01 December 2003

Diagnosis of gastric adenocarcinoma using a scoring system: combined assay of serological markers of Helicobacter pylori infection, pepsinogen I and gastrin.

scientific article published on April 1995

Discovering joint associations between disease and gene pairs with a novel similarity test.

scientific article

Does exercise training during hemodialysis really improve dialysis efficacy?

scientific article published on 01 January 2007

Elevated aspartate and alanine aminotransferase levels and natural death among patients with methamphetamine dependence

scientific article

Epidemiology of multiple myeloma in Taiwan: increasing incidence for the past 25 years and higher prevalence of extramedullary myeloma in patients younger than 55 years

scientific article published in August 2007

Estimating genotype relative risks in case-parental control studies: an optimal weighting approach

scientific article published on 01 September 2000

Estimating pathogen-specific asymptomatic ratios

scientific article published in September 2010

Estimating risks and relative risks in case-base studies under the assumptions of gene-environment independence and Hardy-Weinberg equilibrium

scientific article

Estimation of a common effect parameter from follow-up data when there is no mechanistic interaction

scientific article

Evaluation of the Normality Assumption in Meta-analyses

scientific article published on 29 November 2019

Excess relative risk as an effect measure in case-control studies of rare diseases

scientific article published on January 2014

Factors affecting the natural decay of hepatitis B surface antigen in children with chronic hepatitis B virus infection during long-term follow-up.

scientific article published on 8 August 2014

False Appearance of Gene-Environment Interactions in Genetic Association Studies

scientific article published on March 2016

Fifteen-year population attributable fractions and causal pies of risk factors for newly developed hepatocellular carcinomas in 11,801 men in Taiwan

scientific article

Forecasting Hepatocellular Carcinoma Mortality in Taiwan Using an Age-Period-Cohort Model ⬇️

scientific article published on October 6, 2011

Genetic association studies of adult-onset diseases using the case-spouse and case-offspring designs

scientific article published on 01 December 2003

Genetic polymorphisms of nerve growth factor receptor (NGFR) and the risk of Alzheimer's disease.

scientific article

Hazard ratio bias in cohort studies.

scientific article

Identification of genetic heterogeneity of Alzheimer's disease across age

scientific article published on 12 March 2019

Immediate and medium-term effects of custom-moulded insoles on pain, physical function, physical activity, and balance control in patients with knee osteoarthritis

scientific article published on 01 February 2014

Importance of presenting the variability of the false discovery rate control.

scientific article published on 4 August 2015

Improving Power of Genome-Wide Association Studies with Weighted False Discovery Rate Control and Prioritized Subset Analysis ⬇️

scientific article published on April 9, 2012

Incidence of first onset alcohol use disorder: a 16-year follow-up in the Taiwanese aborigines.

scientific article published on 11 October 2012

Incorporating prior knowledge to facilitate discoveries in a genome-wide association study on age-related macular degeneration

scientific article

Local and systemic cardiovascular effects from monochromatic infrared therapy in patients with knee osteoarthritis: a double-blind, randomized, placebo-controlled study

scientific article

Male gender is a risk factor for recurrent appendicitis following nonoperative treatment

scientific article published on 01 July 2011

Mapping disease-susceptibility genes in admixed populations using interval principal component tests

scientific article published on 01 September 2004

Maximal cardiovascular fitness and its correlates in ambulatory hemodialysis patients

scientific article published in July 2006

MicroRNA expression aberration associated with bronchopulmonary dysplasia in preterm infants: a preliminary study.

scientific article

Mortality trends of liver diseases from 1981 to 2016 and the projection to 2035 in Taiwan: An age-period-cohort analysis

scientific article published on 17 February 2019

Multilevel analysis of habitual physical activity and metabolic syndrome in Northern Taiwan.

scientific article published on 5 May 2011

One-shot percutaneous electrical nerve stimulation vs. transcutaneous electrical nerve stimulation for low back pain: comparison of therapeutic effects

scientific article published on November 2002

One-step extrapolation of the prediction performance of a gene signature derived from a small study

scientific article

Optimal Trend Tests for Genetic Association Studies of Heterogeneous Diseases.

scientific article published on 09 June 2016

Pain, Physical Function, and Health in Patients with Knee Osteoarthritis.

scientific article published on 22 September 2015

Performance Metrics for Selecting Single Nucleotide Polymorphisms in Late-onset Alzheimer's Disease.

scientific article

Population stratification bias in the case-only study for gene-environment interactions

scientific article published on 22 May 2008

Postural stability in patients with knee osteoarthritis: comparison with controls and evaluation of relationships between postural stability scores and International Classification of Functioning, Disability and Health components

scientific article published on 4 October 2012

Potential for gene-gene confounding bias in case-parental control studies

scientific article

Predicting the risk of osteopenia for women aged 40-55 years.

scientific article published on 15 February 2017

Presenting the Uncertainties of Odds Ratios Using Empirical-Bayes Prediction Intervals ⬇️

scientific article published on February 21, 2012

Probabilistic analysis of global performances of diagnostic tests: interpreting the Lorenz curve-based summary measures.

scientific article

Protective and risk factors for inpatient suicides: a nested case-control study

scientific article published on 12 March 2014

Psychiatric discharge against medical advice is a risk factor for suicide but not for other causes of death

scientific article published in June 2010

Quality of life and impact of children with unclassified developmental delays

scientific article

Quality of life, health satisfaction and family impact on caregivers of children with developmental delays

scientific article published on 8 January 2009

Reducing population stratification bias: stratum matching is better than exposure

scientific article published on 10 July 2008

Sample size calculations for additive interactions.

scientific article published in September 2013

Searching for disease-susceptibility loci by testing for Hardy-Weinberg disequilibrium in a gene bank of affected individuals.

scientific article

Second-generation antipsychotic medications and risk of pneumonia in schizophrenia.

scientific article

Secular trends in liver cancer incidence from 1997 to 2014 in Taiwan and projection to 2035: An age-period-cohort analysis

scientific article published on 14 July 2018

Selecting diagnostic tests for ruling out or ruling in disease: the use of the Kullback-Leibler distance

scientific article published in June 1999

Sharp bounds on sufficient-cause interactions under the assumption of no redundancy

scientific article

Short-term effects of 890-nanometer radiation on pain, physical activity, and postural stability in patients with knee osteoarthritis: a double-blind, randomized, placebo-controlled study

scientific article published on 28 March 2012

Short-term family-centered workshop for children with developmental delays enhances family functioning and satisfaction: A prospective clinical trial.

scientific article published on August 2016

Short-term therapeutic effects of 890-nanometer light therapy for chronic low back pain: a double-blind randomized placebo-controlled study.

scientific article

Sibling recurrence risk ratio analysis of the metabolic syndrome and its components over time.

scientific article published on 31 December 2003

Simple formulas for gauging the potential impacts of population stratification bias

scientific article published on 19 September 2007

Standardization using the harmonically weighted ratios: internal and external comparisons ⬇️

scientific article published on January 30, 2002

Standardization using the harmonically weighted ratios: internal and external comparisons. Wen-Chung Lee, Statistics in Medicine 2002; 21: 247-261

scientific article published on 01 April 2003

Studying the causes of adverse drug reactions: circumvent the warning-interfered bias using the case-case comparison approach.

scientific article published on 14 January 2008

Sufficient-cause modeling with matched data using SAS

scientific article published on 01 November 2013

Suicide and Other-Cause Mortality after Early Exposure to Smoking and Second Hand Smoking: A 12-Year Population-Based Follow-Up Study

scientific article published on 29 July 2015

Survival after resection of gastric cancer and prognostic relevance of systematic lymph node dissection: twenty years experience in Taiwan

scientific article published on 01 September 1995

Taiwan's Nationwide Cancer Registry System of 40 years: Past, present, and future

scientific article published on 14 February 2019

Testing for Sufficient-Cause Gene-Environment Interactions Under the Assumptions of Independence and Hardy-Weinberg Equilibrium.

scientific article

Testing for candidate gene linkage disequilibrium using a dense array of single nucleotide polymorphisms in case-parents studies

scientific article published on September 2002

Testing for mechanistic interactions in long-term follow-up studies

scientific article

Testing synergisms in a no-redundancy sufficient-cause rate model.

scientific article

Testing the genetic relation between two individuals using a panel of frequency-unknown single nucleotide polymorphisms.

scientific article published in November 2003

The Impact of Short-Term Video Games on Performance among Children with Developmental Delays: A Randomized Controlled Trial

scientific article

The suicide mortality rates between 1997-1998 and 2000-2001 in Nantou County of Taiwan following the earthquake of September 21 in 1999.

scientific article

Therapeutic effects of short-term monochromatic infrared energy therapy on patients with knee osteoarthritis: a double-blind, randomized, placebo-controlled study

scientific article published on 5 September 2012

Trends in mortality from diabetes mellitus in Taiwan, 1960-1988.

scientific article published on October 1992

Two-way minimization: a novel treatment allocation method for small trials

scientific article

Weighing the causal pies in case-control studies

scientific article published on 01 July 2010

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