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List of works by Mirella Giovarelli

5-Fluorocytosine-induced eradication of murine adenocarcinomas engineered to express the cytosine deaminase suicide gene requires host immune competence and leaves an efficient memory.

scientific article published in May 1995

A "stealth effect": adenocarcinoma cells engineered to express TRAIL elude tumor-specific and allogeneic T cell reactions

scientific article published in November 1999

A novel leukemia T-cell line (PF-382) with phenotypic and functional features of suppressor lymphocytes

scientific article published on August 1985

Activin A induces Langerhans cell differentiation in vitro and in human skin explants

scientific article

Alloantigen requirements for nonproliferative activation of t lymphocytes

scientific article published on April 1, 1979

Alloantigen-activated lymphocytes from mice bearing a spontaneous "nonimmunogenic" adenocarcinoma inhibit its growth in vivo by recruiting host immunoreactivity

scientific article published in November 1985

An efficient Th2-type memory follows CD8+ lymphocyte-driven and eosinophil-mediated rejection of a spontaneous mouse mammary adenocarcinoma engineered to release IL-4.

scientific article published on December 1994

An integrated humoral and cellular response is elicited in pancreatic cancer by alpha-enolase, a novel pancreatic ductal adenocarcinoma-associated antigen

scientific article

Antitumor Efficacy of Adenocarcinoma Cells Engineered to Produce Interleukin 12 (IL-12) or Other Cytokines Compared With Exogenous IL-12 ⬇️

scientific article published on July 16, 1997

Autoantibodies to Ezrin are an early sign of pancreatic cancer in humans and in genetically engineered mouse models

scientific article published on 06 September 2013

Autoantibody signature in human ductal pancreatic adenocarcinoma.

scientific article published on 8 September 2007

B cells from chronic lymphocytic leukemia (CLL) patients are strong inducers of proliferation and major histocompatibility complex (MHC)-unrestricted [natural killer (NK)-like] cytotoxicity in normal T-lymphocytes

scientific article

B7h triggering inhibits the migration of tumor cell lines.

scientific article

CCL16 activates an angiogenic program in vascular endothelial cells.

scientific article published on 4 September 2003

CCL16 enhances the CD8+ and CD4+ T cell reactivity to human HER-2 elicited by dendritic cells loaded with rat ortholog HER-2.

scientific article

CCL16/LEC powerfully triggers effector and antigen-presenting functions of macrophages and enhances T cell cytotoxicity

scientific article published on 2 October 2003

Chimeric rat/human HER2 efficiently circumvents HER2 tolerance in cancer patients

scientific article published on 25 March 2014

Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory phenotype and TREM-1 expression

scientific article published on 06 March 2013

Circulating Autoantibodies to Phosphorylated α-Enolase are a Hallmark of Pancreatic Cancer

scientific article published on 10 June 2010

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

scientific article

Control of H-2 expression in transformed nonhaemopoietic cells by autocrine interferon

scientific article

Cytokine-induced tumor immunogenicity: from exogenous cytokines to gene therapy

scientific article

Cytokines, tumour-cell death and immunogenicity: a question of choice

scientific article published on January 1997

DNA vaccination against rat her-2/Neu p185 more effectively inhibits carcinogenesis than transplantable carcinomas in transgenic BALB/c mice

scientific article published in November 2000

Death receptor ligands in tumors

scientific article

Effect of prolonged administration of low doses of dietary retinoids on cell-mediated immunity and the growth of transplantable tumors in mice

scientific article published in March 1986

Enhanced cytotoxic effect of camptothecin nanosponges in anaplastic thyroid cancer cells in vitro and in vivo on orthotopic xenograft tumors.

scientific article published in November 2017

Enhancement versus tumor resistance induced by different levels of immunodepression in BALB/c mice with protozoan infections

scientific article published on January 1979

Evolution of macrophage immune recognition of viral, bacterial, protozoal and allo-antigens

Expression of IFNγR2 mutated in a dileucine internalization motif reinstates IFNγ signaling and apoptosis in human T lymphocytes

scientific article published on 13 August 2010

From exogenous cytokines to gene therapy: cytokine activated tumor inhibition.

scientific article

Growth and dissemination of human malignant lymphoblasts in immunosuppressed nu/nu mice

scientific article published on January 1, 1991

H-2-restriction and Ia-dependence of the efficient immune recognition of minor histocompatibility antigens in vivo

Helper strategy in tumor immunology: expansion of helper lymphocytes and utilization of helper lymphokines for experimental and clinical immunotherapy

scientific article

Human dendritic cells differentiated in hypoxia down-modulate antigen uptake and change their chemokine expression profile

scientific article published on 25 August 2008

Human mesenchymal stem cell-derived microvesicles modulate T cell response to islet antigen glutamic acid decarboxylase in patients with type 1 diabetes

article

Human mesenchymal stem cells modulate cellular immune response to islet antigen glutamic acid decarboxylase in type 1 diabetes

scientific article published on 13 May 2010

Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo

article

IGF-1 down-regulates IFN-gamma R2 chain surface expression and desensitizes IFN-gamma/STAT-1 signaling in human T lymphocytes.

scientific article published on 3 July 2003

IL-10 enhances CCL2 release and chemotaxis induced by CCL16 in human monocytes

scientific article

IL-6, but not IFN-gamma, triggers apoptosis and inhibits in vivo growth of human malignant T cells on STAT3 silencing.

scientific article

Immune depression in Trypanosoma brucei brucei infected mice. Sequential histological and immunological findings

scientific article published on January 1, 1981

Immune recognition of tumor cellsin vivo. I. Role of H-2 gene products in T lymphocyte activation against minor histocompatibility antigens displayed by adenocarcinoma cells

article

Immunological mechanisms elicited at the tumour site by lymphocyte activation gene-3 (LAG-3) versus IL-12: sharing a common Th1 anti-tumour immune pathway

scientific article

Immunoregulatory T-cell defects in B-cell chronic lymphocytic leukemia: cause or consequence of the disease? The contributory role of decreased availability of interleukin 2 (IL-2).

scientific article published on January 1987

In the absence of IGF-1 signaling, IFN-gamma suppresses human malignant T-cell growth

scientific article published on 5 December 2006

In vitro and in vivo immunomodulatory activity of ST 789 on two human lymphoblastic T cell lines

scientific article published on January 1, 1992

In vitro and in vivo immunomodulatory activity of an N-9 arginyl hypoxanthine derivative (PCF-39).

scientific article published on January 1987

In vitro arming and blocking activity of sera from BALB/c mice bearing a spontaneous transplantable adenocarcinoma

scientific article published on 01 November 1977

In vitro reeducated T helper cells from sarcoma-bearing mice inhibit sarcoma growth in vivo.

scientific article

Induction of resistance or enhancement to a transplantable murine plasmacytoma by transfer of non-immune leucocytes ⬇️

scientific article published on September 1, 1976

Inhibition of interferon-gamma may suppress allograft reactivity by T lymphocytes in vitro and in vivo

scientific article published in Science

Interaction between endothelial cells and the secreted cytokine drives the fate of an IL4- or an IL5-transduced tumour

scientific article published on December 1998

Interaction of H-2 and non-H-2 genes in spontaneous resistance to adenocarcinoma ADK-1t in F1 mice

scientific article

Interferon-activated tumor inhibitionin vivo. Small amounts of interferon-gamma inhibit tumor growth by eliciting host systemic immunoreactivity

scientific article published on 01 January 1986

Interleukin 12-mediated prevention of spontaneous mammary adenocarcinomas in two lines of Her-2/neu transgenic mice.

scientific article

Interleukin-induced tumor immunogenicity.

scientific article published on January 1994

Intralesional injection of adenovirus encoding CC chemokine ligand 16 inhibits mammary tumor growth and prevents metastatic-induced death after surgical removal of the treated primary tumor

scientific article published on April 2004

Iron regulates T-lymphocyte sensitivity to the IFN-gamma/STAT1 signaling pathway in vitro and in vivo

scientific article published on 30 December 2004

Is antibody-dependent cellular cytotoxicity an important mechanism of resistance to tumors in vivo?

scientific article

Lack of plasma protein hemopexin dampens mercury-induced autoimmune response in mice

scientific journal article

Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells

scientific article published on 25 March 2008

Local release of IL-10 by transfected mouse mammary adenocarcinoma cells does not suppress but enhances antitumor reaction and elicits a strong cytotoxic lymphocyte and antibody-dependent immune memory

scientific article published in September 1995

Local release of interleukin-10 by transfected mouse adenocarcinoma cells exhibits pro- and anti-inflammatory activity and results in a delayed tumor rejection

scientific article published on March 1, 1998

Low doses of IL-4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently nonimmunogenic tumors and induce a tumor-specific immune memory.

scientific article published on November 1990

Ly-6A/E gene is widely expressed among transformed nonhematopoietic cells. Autocrine modulation by interferon

scientific article published on November 1992

Lymphokine production in mouse mixed lymphocyte reaction (MLR)

Lymphokine production in primary mixed lymphocyte culture (MLC). III. Alloantigen signals cell-cell interactions involved in migration inhibition factor and immune interferon release

scientific article published on May 31, 1979

Lymphokine-activated tumor inhibition in mice. Ability of a nonapeptide of the human IL-1 beta to recruit anti-tumor reactivity in recipient mice

scientific article published in January 1989

Lymphokine-activated tumor inhibition in vivo. I. The local administration of interleukin 2 triggers nonreactive lymphocytes from tumor-bearing mice to inhibit tumor growth

scientific article published in February 1985

Lymphokine-activated tumor inhibition: Combinatory activity of a synthetic nonapeptide from interleukin-1, interleukin-2, interleukin-4, and interferon-γ injected around tumor-draining lymph nodes

Modulation of interferon-gamma receptor during human T lymphocyte alloactivation

scientific article

Molecular approaches to cancer immunotherapy

scientific article published on December 1, 1995

Monocytes and dendritic cells in a hypoxic environment: Spotlights on chemotaxis and migration

scientific article published on 21 September 2008

PHAGE-BASED ANTI-HER2 VACCINATION CAN CIRCUMVENT IMMUNE TOLERANCE AGAINST BREAST CANCER

article by Caterina Bartolacci et al published 16 October 2018 in Cancer immunology research

Perilymphatic injections of cytokines: a new tool in active cancer immunotherapy. Experimental rationale and clinical findings

scientific article published on January 1990

Phage-Based Anti-HER2 Vaccination Can Circumvent Immune Tolerance against Breast Cancer

Physiological and pathological influences of central nervous system on the immune system: a critical appraisal

scientific article

Pro-inflammatory profile of preeclamptic placental mesenchymal stromal cells: new insights into the etiopathogenesis of preeclampsia

scientific article

Production and function of activin A in human dendritic cells

scientific article

Radiofrequency destruction of the tuberoinfundibular region of hypothalamus permanently abrogates NK cell activity in mice

scientific article published in November 1983

Regulation of Human Macrophage M1-M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1.

scientific article published on 7 September 2017

Release of interleukin-2-like material by b-chronic lymphocytic leukemia cells. An autocrine or paracrine model of production and utilization?

scientific article published on 01 January 1988

Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma

scientific article published on 27 September 2005

Role of neutrophils and CD4+ T lymphocytes in the primary and memory response to nonimmunogenic murine mammary adenocarcinoma made immunogenic by IL-2 gene

scientific article published in December 1992

Rous sarcoma virus-induced tumors in mice--I. Macrophage-mediated natural cytotoxicity

scientific article published in March 1982

Rous sarcoma virus-induced tumours in mice. II. Contribution of H-2 and non-H-2 alloantigen barriers to tumour immunogenicity in vivo ⬇️

scientific article published on June 1, 1983

Solid lipid nanoparticles of cholesteryl butyrate inhibit the proliferation of cancer cells in vitro and in vivo models.

scientific article published on September 2013

Source of tumor cells influences their immune recognition by H-2-matched mice

scientific article published on June 1, 1979

Strategies for cell-mediated immunotherapy of cancer: killing or help?

scientific article published on 01 July 1986

Strategies for cytokine utilisation in tumor therapy.

scientific article

Sulfated K5 Escherichia coli polysaccharide derivatives as wide-range inhibitors of genital types of human papillomavirus.

scientific article published on 4 February 2008

Suppression of proliferative response and lymphokine production during the progression of a spontaneous tumor ⬇️

scientific article published on December 1, 1979

Suppressor macrophages in tumor-bearing mice. Inconsistency between in vivo and in vitro findings? ⬇️

scientific article published on June 15, 1982

Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway

scientific article

The dream of effective cytokine-based tumor vaccines

scientific article published on September 1, 1997

The hypoxic environment reprograms the cytokine/chemokine expression profile of human mature dendritic cells

scientific article

The interferon-inducible IFI16 gene inhibits tube morphogenesis and proliferation of primary, but not HPV16 E6/E7-immortalized human endothelial cells

scientific article (publication date: 15 February 2004)

The interferon-inducible gene IFI16 secretome of endothelial cells drives the early steps of the inflammatory response

scientific article

The macrophage as the social interconnection within the immune system

scientific article published on January 1980

The proapoptotic activity of the Interferon-inducible gene IFI16 provides new insights into its etiopathogenetic role in autoimmunity

scientific article

Therapy of murine mammary carcinoma metastasis with interferon gamma and MHC gene-transduced tumour cells

scientific article

Transcriptome of Hypoxic Immature Dendritic Cells: Modulation of Chemokine/Receptor Expression

scientific article published on 01 February 2008

Triggering of B7h by the ICOS modulates maturation and migration of monocyte-derived dendritic cells

scientific article published on 28 December 2012

Tumor immunotherapy by local injection of interleukin 2 and non-reactive lymphocytes. Experimental and clinical results

scientific article

Tumour inhibition by interleukin-2 at the tumour/host interface

scientific article

Vaccination with ENO1 DNA prolongs survival of genetically engineered mice with pancreatic cancer.

scientific article published on 16 January 2013

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