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List of works by Maurizio Pocchiari

3-D changes in neuroblastoma x glioma hybrid (NG 108-15) cell differentiation as studied by SEM and TEM.

scientific article published in January 1989

A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk

scientific article published on January 2014

A new point mutation of the prion protein gene in Creutzfeldt-Jakob disease.

scientific article published on December 1993

A new variant of Creutzfeldt-Jakob disease in the UK.

scientific article

A novel PSEN2 mutation associated with a peculiar phenotype

scientific article published in April 2008

A rapid and efficient method for the detection of point mutations of the human prion protein gene (PRNP) by direct sequencing.

scientific article

A retrospective study of Creutzfeldt-Jakob disease in Italy (1972-1986).

scientific article published on December 1988

A role for complement in transmissible spongiform encephalopathies

scientific article published on 01 April 2001

A test for Creutzfeldt-Jakob disease using nasal brushings

scientific article

Advanced tests for early and accurate diagnosis of Creutzfeldt-Jakob disease

scientific article published on 17 June 2016

Advanced tests for early and accurate diagnosis of Creutzfeldt-Jakob disease

scientific article

Age at Death of Creutzfeldt-Jakob disease in subsequent family generation carrying the E200K mutation of the prion protein gene

scientific article

Age at onset of genetic (E200K) and sporadic Creutzfeldt-Jakob diseases is modulated by the gene

article

Alpha1 antichymotrypsin signal peptide polymorphism in sporadic Creutzfeldt-Jakob disease

scientific article published in May 1997

Amphotericin B delays the incubation period of scrapie in intracerebrally inoculated hamsters.

scientific article published in January 1987

Amphotericin B treatment dissociates in vivo replication of the scrapie agent from PrP accumulation

scientific article published on April 16, 1992

Analysis of EEG and CSF 14-3-3 proteins as aids to the diagnosis of Creutzfeldt-Jakob disease

scientific article published on 01 September 2000

Ancestral origins and worldwide distribution of the PRNP 200K mutation causing familial Creutzfeldt-Jakob disease

scientific article

Apolipoprotein E in sporadic and familial Creutzfeldt-Jakob disease

scientific article published on 01 October 1995

Assessing prion infectivity of human urine in sporadic Creutzfeldt-Jakob disease

scientific article published in January 2012

Assessment of prion reduction filters in decreasing infectivity of ultracentrifuged 263K scrapie-infected brain homogenates in "spiked" human blood and red blood cells

scientific article published on 5 August 2013

BSE and variant Creutzfeldt-Jakob disease: never say never

scientific article published on 13 April 2002

Bovine spongiform encephalopathy: an overview

scientific article published on 01 January 1992

Can potential hazard of Creutzfeldt-Jakob disease infectivity be reduced in the production of human growth hormone? Inactivation experiments with the 263K strain of scrapie. Rapid communication

scientific article published on 01 January 1988

Cerebrospinal Fluid Total Prion Protein in the Spectrum of Prion Diseases

scientific article published on 30 July 2018

Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias: a longitudinal multicentre study over 10 years

scientific article

Cerebrospinal fluid biomarkers in human genetic transmissible spongiform encephalopathies

scientific article

Cerebrospinal fluid real-time quaking-induced conversion is a robust and reliable test for sporadic creutzfeldt-jakob disease: An international study

scientific article published on 30 April 2016

Characterisation of antisera raised against species-specific peptide sequences from scrapie-associated fibril protein and their application for post-mortem immunodiagnosis of spongiform encephalopathies

scientific article published in January 1994

Choline acetyltransferase activity and [3H]quinuclidinylbenzilate binding in brains of scrapie-infected hamsters

scientific article published in September 1984

Chronic wasting disease and atypical forms of bovine spongiform encephalopathy and scrapie are not transmissible to mice expressing wild-type levels of human prion protein.

scientific article published on 11 April 2012

Clinical and neuropathological phenotype associated with the novel V189I mutation in the prion protein gene

article

Clinical trials and methodological problems in prion diseases

scientific article published in September 2009

Clinicopathological features of the rare form of Creutzfeldt-Jakob disease in R208H-V129V PRNP carrier

scientific article published on 21 March 2019

Codon 129 polymorphism of prion protein gene in sporadic Alzheimer's disease

scientific article published in February 2008

Codon 129 prion protein genotype and sporadic Creutzfeldt-Jakob disease

scientific article published on 01 May 1999

Codon 200 mutation in a new family of Chilean origin with Creutzfeldt-Jakob disease.

scientific article published on July 1996

Comparison between plasma and cerebrospinal fluid biomarkers for the early diagnosis and association with survival in prion disease

scientific article published on 14 September 2020

Comparison of nanofiltration efficacy in reducing infectivity of centrifuged versus ultracentrifuged 263K scrapie-infected brain homogenates in "spiked" albumin solutions

scientific article published on 14 November 2011

Concluding remarks

scientific article published on 01 January 2018

Congo red prolongs the incubation period in scrapie-infected hamsters.

scientific article published on January 1995

Creutzfeld-Jakob disease in the province of Siena: two cases transmitted to monkeys

scientific article published on 01 April 1983

Creutzfeldt-Jakob disease after non-commercial dura mater graft

scientific article published in The Lancet

Creutzfeldt-Jakob disease and related disorders: etiopathogenetic aspects

scientific article published on May 1, 1997

Creutzfeldt-Jakob disease in Europe

scientific article published on 01 September 1995

Creutzfeldt-Jakob disease in Italy

scientific article published on 01 November 1991

Creutzfeldt-Jakob disease masked by head trauma and features of Wilson's disease

scientific article published on 7 January 2015

Creutzfeldt-Jakob disease mortality in Italy, 1982-1996.

scientific article

Creutzfeldt-Jakob disease: hopes for therapy

scientific article published on 01 May 2008

Cyclooxygenase-2, prostaglandin E2, and microglial activation in prion diseases

scientific article (publication date: 2007)

Detection of exosomal prions in blood by immunochemistry techniques

scientific article published on 24 March 2015

Detection of pathologic prion protein in the olfactory epithelium in sporadic Creutzfeldt-Jakob disease

scientific article published in February 2003

Detection of proteinase-resistant protein (PrP) in small brain tissue samples from Creutzfeldt-Jakob disease patients.

scientific article published in July 1994

Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease

scientific article published in July 2006

Diagnosis of Creutzfeldt-Jakob disease. Routine tonsil biopsy for diagnosis of new variant Creutzfeldt-Jakob disease is not justified

scientific article

Diagnosis of Human Prion Disease Using Real-Time Quaking-Induced Conversion Testing of Olfactory Mucosa and Cerebrospinal Fluid Samples

scientific article published on 12 December 2016

Diagnostic Accuracy of Prion Disease Biomarkers in Iatrogenic Creutzfeldt-Jakob Disease

scientific article published on 12 February 2020

Doxycycline in Creutzfeldt-Jakob disease: a phase 2, randomised, double-blind, placebo-controlled trial.

scientific article published on 8 January 2014

Early identification of variant Creutzfeldt-Jakob disease ⬇️

scientific article published on February 21, 1998

Efficacy of phthalocyanine tetrasulfonate against mouse-adapted human prion strains.

scientific article

Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles

scientific article

Epidemic of transmissible spongiform encephalopathy in sheep and goats in Italy

scientific article published in The Lancet

Evaluation of Human Cerebrospinal Fluid Malate Dehydrogenase 1 as a Marker in Genetic Prion Disease Patients

scientific article published on 28 November 2019

Experimental drug treatment of scrapie: A pathogenetic basis for rationale therapeutics ⬇️

scientific article published on September 1, 1991

Expression of wild-type and V210I mutant prion protein in human neuroblastoma cells

scientific article published in July 1999

Extended and direct evaluation of RT-QuIC assays for Creutzfeldt-Jakob disease diagnosis

scientific article published on 27 December 2016

Failure to ameliorate Creutzfeldt-Jakob disease with amphotericin B therapy

scientific article published on 01 April 1992

Genetic prion disease: the EUROCJD experience

scientific article published on 15 November 2005

Genomic and post-genomic analyses of human prion diseases

scientific article

Gerstmann-Sträussler-Scheinker syndrome with variable phenotype in a new kindred with PRNP-P102L mutation

scientific article published on 19 September 2013

Health professions and risk of sporadic Creutzfeldt-Jakob disease, 1965 to 2010

scientific article

Heidenhain variant in two patients with inherited V210I Creutzfeldt-Jakob disease

scientific article published on 13 August 2015

High incidence of Creutzfeldt-Jakob disease in rural Calabria, Italy

scientific article published in December 1998

High incidence of genetic human transmissible spongiform encephalopathies in Italy

scientific article published on 01 May 2005

Highly Infectious Purified Preparations of Disease-Specific Amyloid of Transmissible Spongiform Encephalopathies Are Not Devoid of Nucleic Acids of Viral Size ⬇️

scientific article published on January 1, 1997

Human transmissible spongiform encephalopathies in eleven countries: diagnostic pattern across time, 1993-2002.

scientific article published on 10 November 2006

Iatrogenic Creutzfeldt-Jakob disease at the millennium.

scientific article

Iatrogenic Creutzfeldt-Jakob disease with Amyloid-β pathology: an international study

scientific article published on 8 January 2018

Iatrogenic Creutzfeldt-Jakob disease, final assessment

scientific article

Identification of misfolded proteins in body fluids for the diagnosis of prion diseases

scientific article published on 21 August 2013

Identification of the pathological prion protein allotypes in scrapie-infected heterozygous bank voles (Clethrionomys glareolus) by high-performance liquid chromatography-mass spectrometry

scientific article

Inactivation of transmissible spongiform encephalopathy agents in food products by ultra high pressure-temperature treatment

scientific article published on 24 February 2006

Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification

scientific article published on 29 August 2009

Incidence of Creutzfeldt-Jakob disease in Europe in 1993

scientific article published on 01 April 1994

Increased CSF levels of prostaglandin E 2 in variant Creutzfeldt–Jakob disease ⬇️

scientific article published on January 8, 2002

Increased brain synthesis of prostaglandin E2 and F2-isoprostane in human and experimental transmissible spongiform encephalopathies

scientific article published on 01 October 2000

Increased levels of acute-phase inflammatory proteins in plasma of patients with sporadic CJD.

scientific article published in August 2012

Influence of timing on CSF tests value for Creutzfeldt-Jakob disease diagnosis

scientific article published on 25 March 2007

Isonicotinic hydrazide causes seizures in scrapie-infected hamsters with shorter latency than in control animals: a possible GABAergic defect

scientific article published in February 1985

KDEL-tagged anti-prion intrabodies impair PrP lysosomal degradation and inhibit scrapie infectivity

scientific article

Levels of infectivity in the blood throughout the incubation period of hamsters peripherally injected with scrapie

scientific article published in January 1989

Management and prevention of human prion diseases

scientific article published in November 2009

Methodological aspects of the validation of purification procedures of human/animal-derived products to remove unconventional slow viruses.

scientific article published on January 1991

Methods for inactivating experimentally induced scrapie in hamster tissues

scientific article published on 01 May 1990

Migration of dendritic cells into the brain in a mouse model of prion disease

scientific article published in August 2005

Modification of tritiated gamma-amino-n-butyric acid transport in rabies virus-infected primary cortical cultures.

scientific article published in March 1994

Molecular diagnostics of transmissible spongiform encephalopathies

scientific article

Molecular forms of cholinesterases in CSF of Alzheimer's disease/senile dementia of Alzheimer type patients and matched neurological controls

scientific article published in February 1986

Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada

scientific article published in May 2005

Mortality from Human Transmissible Spongiform Encephalopathies: A Record Linkage Study

scientific article published on 12 April 2005

Mortality trend from sporadic Creutzfeldt-Jakob disease (CJD) in Italy, 1993-2000.

scientific article

Mutant PrPCJD prevails over wild-type PrPCJD in the brain of V210I and R208H genetic Creutzfeldt-Jakob disease patients.

scientific article

Mutation of the PRNP gene at codon 211 in familial Creutzfeldt-Jakob disease

scientific article published on 01 October 2001

Need to improve clinical trials in rare neurodegenerative disorders

scientific article published on January 2011

Neurofilaments in blood is a new promising preclinical biomarker for the screening of natural scrapie in sheep

scientific article published on 19 December 2019

Neuroinvasion of the 263K scrapie strain after intranasal administration occurs through olfactory-unrelated pathways

scientific article published on 24 December 2008

Novel prion protein conformation and glycotype in Creutzfeldt-Jakob disease

scientific article

Oral pravastatin prolongs survival time of scrapie-infected mice

scientific article published on 12 March 2009

Pathological prion protein in muscles of hamsters and mice infected with rodent-adapted BSE or vCJD.

scientific article published in January 2006

Patient with rapidly evolving neurological disease with neuropathological lesions of Creutzfeldt-Jakob disease, Lewy body dementia, chronic subcortical vascular encephalopathy and meningothelial meningioma

scientific article

Peripheral neuropathy in the course of progressive systemic sclerosis: light and ultrastructural study

scientific article published on December 1982

Phenotypic variability of Gerstmann-Sträussler-Scheinker disease is associated with prion protein heterogeneity.

scientific article published in October 1998

Polymorphism at codon 129 or codon 219 of PRNP and clinical heterogeneity in a previously unreported family with Gerstmann-Sträussler-Scheinker disease (PrP-P102L mutation)

scientific article published on 01 September 1996

Polymorphisms of the Prion Protein gene in italian patients with Creutzfeldt-Jakob disease

article

Polymorphisms of the prion protein gene in Italian patients with Creutzfeldt-Jakob disease.

scientific article published in October 1994

PrPTSE in muscle-associated lymphatic tissue during the preclinical stage of mice infected orally with bovine spongiform encephalopathy

scientific article published on 17 June 2009

Pre-symptomatic detection of prions by cyclic amplification of protein misfolding.

scientific article published in January 2005

Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies.

scientific article

Preparation of soluble infectious samples from scrapie-infected brain: a new tool to study the clearance of transmissible spongiform encephalopathy agents during plasma fractionation

scientific article published in April 2006

Prevalence of variant CJD in the UK.

scientific article

Prion (PrPres) allotypes profiling: a new perspectives from mass spectrometry

scientific article published on January 2004

Prion Strain Characterization of a Novel Subtype of Creutzfeldt-Jakob Disease.

scientific article

Prion protein glycotype analysis in familial and sporadic Creutzfeldt-Jakob disease patients

scientific article

Prion-specific and surrogate CSF biomarkers in Creutzfeldt-Jakob disease: diagnostic accuracy in relation to molecular subtypes and analysis of neuropathological correlates of p-tau and Aβ42 levels

scientific article published on 15 February 2017

Prions and related neurological diseases

scientific article published in January 1994

Progressive Dementia in a Young Patient with a Homozygous Deletion of the PrP Gene

article

Proteinase-resistant protein in human neuroblastoma cells infected with brain material from Creutzfeldt-Jakob patient

scientific article published in March 1995

Proteomic profiling of PrP27-30-enriched preparations extracted from the brain of hamsters with experimental scrapie

scientific article published in August 2009

Quantitative profiling of the pathological prion protein allotypes in bank voles by liquid chromatography-mass spectrometry.

scientific article

Recent Italian FFI cases.

scientific article published in July 1998

Regulation of intrinsic prion protein by growth factors and TNF-alpha: the role of intracellular reactive oxygen species

scientific article published in September 2003

Rethinking of doxycycline therapy in Creutzfeldt-Jakob disease

scientific article published on 28 January 2015

Revisiting the Heidenhain Variant of Creutzfeldt-Jakob Disease: Evidence for Prion Type Variability Influencing Clinical Course and Laboratory Findings

scientific article published on December 2015

Role of proteomics in understanding prion infection

scientific article published on December 2012

Scrapie infectivity is quickly cleared in tissues of orally-infected farmed fish

scientific article published on 15 June 2006

Sensitivity to biases of case-control studies on medical procedures, particularly surgery and blood transfusion, and risk of Creutzfeldt-Jakob disease.

scientific article published on 05 July 2012

Serotoninergic system in scrapie-infected hamsters

Small virus-like structure in brains from cases of sporadic and familial Creutzfeldt-Jakob disease

scientific article published in October 1994

Sporadic Creutzfeldt-Jakob disease subtype-specific alterations of the brain proteome: impact on Rab3a recycling

scientific article published on 12 December 2012

Sporadic fatal insomnia in a fatal familial insomnia pedigree

scientific article published in March 2008

Study on the activity of cholinesterase and its distribution in molecular form in the cerebrospinal fluid of patients with Alzheimer's disease, a possible diagnostic marker?

scientific article published on 01 January 1986

Sublethal doses of β-amyloid peptide abrogate DNA-dependent protein kinase activity

scientific article

Subtype-specific synaptic proteome alterations in sporadic Creutzfeldt-Jakob disease

scientific article published in January 2013

Sulphate polyanions prolong the incubation period of scrapie-infected hamsters.

scientific article published in March 1992

Survival in Alzheimer's disease is shorter in women carrying heterozygosity at codon 129 of the PRNP gene and no APOE epsilon 4 allele

scientific article published on 07 March 2008

Synthetic scrapie infectivity: interaction between recombinant PrP and scrapie brain-derived RNA.

scientific article

The CNCCS, a benchmark Italian consortium for bioeconomy and an opportunity for the Istituto Superiore di Sanità

scientific article published on 01 January 2012

The pathological prion protein forms ionic conductance in lipid bilayer

scientific article published on 6 June 2011

The scrapie agent and the prion hypothesis.

scientific article published on August 1988

Therapeutical approaches to transmissible spongiform encephalopathies (TSE): the case of amphotericin-B

scientific article published on 01 October 1996

Towards an early clinical diagnosis of sporadic CJD VV2 (ataxic type).

scientific article

Transmission of Creutzfeldt-Jakob disease by dural cadaveric graft

scientific article published on 01 December 1989

Transmission of sporadic Creutzfeldt-Jakob disease by blood transfusion: risk factor or possible biases

scientific article published on 7 January 2011

Transmission of the 263K scrapie strain by the dental route

scientific article published on 01 November 1999

Trapping prion protein in the endoplasmic reticulum impairs PrPC maturation and prevents PrPSc accumulation

scientific article

Ultra-high-pressure inactivation of prion infectivity in processed meat: a practical method to prevent human infection

scientific article

Ultrastructural findings of peripheral nerve in a case of juvenile atypical metachromatic leukodystrophy

scientific article published on October 1, 1979

Ultrastructural studies on synaptic formations in dissociated fetal mouse brain cultures

scientific article published in December 1983

Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease

scientific article published on 22 September 2009

Variant Creutzfeldt-Jakob disease in an Italian woman

scientific article published on 01 September 2002

WHO Consultation on Diagnostic Procedures for Transmissible Spongiform Encephalopathies: Need for Reference Reagents and Reference Panels. Geneva, Switzerland, 22-23 March 1999

scientific article published on 01 September 1999

[Consensus report: tissue handling in suspected Creutzfeldt-Jakob disease and other spongiform encephalopathies (prion diseases) in the human. European Union Biomed-1 Concerted Action]

scientific article published on 01 March 1996

[Creutzfeldt-Jakob disease and other human forms of transmissible spongiform encephalopathy in Italy: a mortality study carried out from different data sources].

scientific article

α-Synuclein RT-QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies

scientific article published on 10 October 2019

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