List of works - Conan K Wang

Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity.

scientific article

Alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms

scientific article

An integrated Java tool for generating amino acid sequence alignments with mapped secondary structure elements

Anchor Residues Guide Form and Function in Grafted Peptides

scientific article published on 02 May 2019

Anti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis. ⬇️

scientific article

Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting

scientific article

Atypical (RIO) protein kinases from Haemonchus contortus--promise as new targets for nematocidal drugs

scientific article published on 22 January 2011

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

scientific article published on 28 August 2017

Bioactive Cyclization Optimizes the Affinity of a Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Peptide Inhibitor

scientific article published on 23 December 2020

Biodistribution of the cyclotide MCoTI-II, a cyclic disulfide-rich peptide drug scaffold.

scientific article

Calcium-Mediated Allostery of the EGF Fold

scientific article published on 09 May 2018

Chlorotoxin: Structure, activity, and potential uses in cancer therapy

scientific article published on 29 September 2015

Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold

scientific article

Comparison of VILIP-1 and VILIP-3 binding to phospholipid monolayers

scientific article

Conformational Flexibility Is a Determinant of Permeability for Cyclosporin.

scientific article published on 5 February 2018

ConoServer, a database for conopeptide sequences and structures

scientific article published on 06 December 2007

CyBase: a database of cyclic protein sequence and structure

scientific article

Cyclic peptide oral bioavailability: Lessons from the past.

scientific article published on 14 May 2016

Cyclotide isolation and characterization

scientific article

Cyclotides are a component of the innate defense of Oldenlandia affinis

scientific article published in January 2010

Cyclotides as natural anti-HIV agents.

scientific article published on January 2008

Cyclotides insert into lipid bilayers to form membrane pores and destabilize the membrane through hydrophobic and phosphoethanolamine-specific interactions

scientific article

Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae

scientific article published in January 2006

Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold

scientific article

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

scientific article

Designing macrocyclic disulfide-rich peptides for biotechnological applications

scientific article published on 16 April 2018

Despite a Conserved Cystine Knot Motif, Different Cyclotides Have Different Membrane Binding Modes

scientific article

Distribution and evolution of circular miniproteins in flowering plants

article

Disulfide-rich macrocyclic peptides as templates in drug design

scientific article published on 06 March 2014

Divalent cations and redox conditions regulate the molecular structure and function of visinin-like protein-1

scientific article

EGF-like and Other Disulfide-rich Microdomains as Therapeutic Scaffolds

scientific article published on 22 December 2019

Effects of Cyclization on Peptide Backbone Dynamics.

scientific article

Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide

scientific article

Exploring experimental and computational markers of cyclic peptides: Charting islands of permeability

scientific article published on 25 April 2015

Extensions of PDZ domains as important structural and functional elements

scientific article

Forward for ICCP2015 issue of Biopolymers Peptide Science

scientific article published on 01 November 2016

Hookworm SCP/TAPS protein structure--A key to understanding host-parasite interactions and developing new interventions

scientific article

Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library

scientific article published on 22 September 2015

Inhibition of tau aggregation using a naturally-occurring cyclic peptide scaffold.

scientific article published on 8 January 2016

Insecticidal spider toxins are high affinity positive allosteric modulators of the nicotinic acetylcholine receptor

scientific article published on 17 May 2019

Insights into the Membrane Interactions of the Saposin-Like Proteins Na-SLP-1 and Ac-SLP-1 from Human and Dog Hookworm

scientific article

Insights into the molecular flexibility of θ-defensins by NMR relaxation analysis

scientific article published on 25 November 2014

Is the Mirror Image a True Reflection? Intrinsic Membrane Chirality Modulates Peptide Binding

scientific article published on 10 December 2019

Isolation and characterization of cytotoxic cyclotides from Viola tricolor

scientific article published on 16 May 2010

Isolation and characterization of peptides from Momordica cochinchinensis seeds

scientific article

Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake

scientific article published on 29 April 2017

Lysine-rich Cyclotides: A New Subclass of Circular Knotted Proteins from Violaceae

scientific article published on 31 August 2015

Mirror Images of Antimicrobial Peptides Provide Reflections on Their Functions and Amyloidogenic Properties

scientific article

NMRDyn: a program for NMR relaxation studies of protein association

scientific article

Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration.

scientific article published on 31 January 2012

Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors

scientific article

Racemic and quasi-racemic X-ray structures of cyclic disulfide-rich peptide drug scaffolds

scientific article

Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients

scientific article

SBAL: a practical tool to generate and edit structure-based amino acid sequence alignments

scientific article

Specific interaction to PIP2 increases the kinetic rate of membrane binding of VILIPs, a subfamily of Neuronal Calcium Sensors (NCS) proteins

scientific article published on 11 July 2014

Structural parameters modulating the cellular uptake of disulfide-rich cyclic cell-penetrating peptides: MCoTI-II and SFTI-1

scientific article published on 24 June 2014

Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species

article

The anthelmintic activity of the cyclotides: natural variants with enhanced activity

scientific article published in August 2008

The cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: A proof-of-concept study using the integrin-binding RGD motif

scientific article

The cyclotide family of circular miniproteins: nature's combinatorial peptide template.

scientific article

The role of conserved Glu residue on cyclotide stability and activity: a structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

scientific article

The role of disulfide bonds in structure and activity of chlorotoxin.

scientific article published on October 2014

Toward Structure Determination of Disulfide-Rich Peptides Using Chemical Shift-Based Methods

scientific article published on 21 February 2019

Translational diffusion of cyclic peptides measured using pulsed-field gradient NMR.

scientific article published on 15 September 2014

Using the MCoTI-II Cyclotide Scaffold To Design a Stable Cyclic Peptide Antagonist of SET, a Protein Overexpressed in Human Cancer

scientific article published on 21 December 2015

List of works by Conan K Wang

Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity.

Alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms

An integrated Java tool for generating amino acid sequence alignments with mapped secondary structure elements

Anchor Residues Guide Form and Function in Grafted Peptides

Anti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis. ⬇️

Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting

Atypical (RIO) protein kinases from Haemonchus contortus--promise as new targets for nematocidal drugs

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

Bioactive Cyclization Optimizes the Affinity of a Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Peptide Inhibitor

Biodistribution of the cyclotide MCoTI-II, a cyclic disulfide-rich peptide drug scaffold.

Calcium-Mediated Allostery of the EGF Fold

Chlorotoxin: Structure, activity, and potential uses in cancer therapy

Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold

Comparison of VILIP-1 and VILIP-3 binding to phospholipid monolayers

Conformational Flexibility Is a Determinant of Permeability for Cyclosporin.

ConoServer, a database for conopeptide sequences and structures

CyBase: a database of cyclic protein sequence and structure

Cyclic peptide oral bioavailability: Lessons from the past.

Cyclotide isolation and characterization

Cyclotides are a component of the innate defense of Oldenlandia affinis

Cyclotides as natural anti-HIV agents.

Cyclotides insert into lipid bilayers to form membrane pores and destabilize the membrane through hydrophobic and phosphoethanolamine-specific interactions

Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae

Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

Designing macrocyclic disulfide-rich peptides for biotechnological applications

Despite a Conserved Cystine Knot Motif, Different Cyclotides Have Different Membrane Binding Modes

Distribution and evolution of circular miniproteins in flowering plants

Disulfide-rich macrocyclic peptides as templates in drug design

Divalent cations and redox conditions regulate the molecular structure and function of visinin-like protein-1

EGF-like and Other Disulfide-rich Microdomains as Therapeutic Scaffolds

Effects of Cyclization on Peptide Backbone Dynamics.

Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide

Exploring experimental and computational markers of cyclic peptides: Charting islands of permeability

Extensions of PDZ domains as important structural and functional elements

Forward for ICCP2015 issue of Biopolymers Peptide Science

Hookworm SCP/TAPS protein structure--A key to understanding host-parasite interactions and developing new interventions

Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library

Inhibition of tau aggregation using a naturally-occurring cyclic peptide scaffold.

Insecticidal spider toxins are high affinity positive allosteric modulators of the nicotinic acetylcholine receptor

Insights into the Membrane Interactions of the Saposin-Like Proteins Na-SLP-1 and Ac-SLP-1 from Human and Dog Hookworm

Insights into the molecular flexibility of θ-defensins by NMR relaxation analysis

Is the Mirror Image a True Reflection? Intrinsic Membrane Chirality Modulates Peptide Binding

Isolation and characterization of cytotoxic cyclotides from Viola tricolor

Isolation and characterization of peptides from Momordica cochinchinensis seeds

Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake

Lysine-rich Cyclotides: A New Subclass of Circular Knotted Proteins from Violaceae

Mirror Images of Antimicrobial Peptides Provide Reflections on Their Functions and Amyloidogenic Properties

NMRDyn: a program for NMR relaxation studies of protein association

Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration.

Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors

Racemic and quasi-racemic X-ray structures of cyclic disulfide-rich peptide drug scaffolds

Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients

SBAL: a practical tool to generate and edit structure-based amino acid sequence alignments

Specific interaction to PIP2 increases the kinetic rate of membrane binding of VILIPs, a subfamily of Neuronal Calcium Sensors (NCS) proteins

Structural parameters modulating the cellular uptake of disulfide-rich cyclic cell-penetrating peptides: MCoTI-II and SFTI-1

Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species

The anthelmintic activity of the cyclotides: natural variants with enhanced activity

The cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: A proof-of-concept study using the integrin-binding RGD motif

The cyclotide family of circular miniproteins: nature's combinatorial peptide template.

The role of conserved Glu residue on cyclotide stability and activity: a structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

The role of disulfide bonds in structure and activity of chlorotoxin.

Toward Structure Determination of Disulfide-Rich Peptides Using Chemical Shift-Based Methods

Translational diffusion of cyclic peptides measured using pulsed-field gradient NMR.

Using the MCoTI-II Cyclotide Scaffold To Design a Stable Cyclic Peptide Antagonist of SET, a Protein Overexpressed in Human Cancer