List of works - Pierre Martineau

A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm

scientific article

A genetic system to elicit and monitor antipeptide antibodies without peptide synthesis.

scientific article published in February 1991

A novel druglike spleen tyrosine kinase binder prevents anaphylactic shock when administered orally

scientific article published on 9 June 2008

ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan-treated metastases.

scientific article published on May 2004

Antibody targeting of claudin-1 as a potential colorectal cancer therapy.

scientific article

Casein interactions studied by the surface plasmon resonance technique.

scientific article published in November 2002

Claudin gene expression profiles and clinical value in colorectal tumors classified according to their molecular subtype

article

Construction of a Synthetic Antibody Gene Library for the Selection of Intrabodies and Antibodies

scientific article published in January 2018

Crystallization of genetically engineered active maltose-binding proteins, including an immunogenic viral epitope insertion.

scientific article

Cyclophilin A as negative regulator of apoptosis by sequestering cytochrome c.

scientific article

Directed evolution of single-chain Fv for cytoplasmic expression using the beta-galactosidase complementation assay results in proteins highly susceptible to protease degradation and aggregation

scientific article

Efficient incorporation of a functional hyper-stable single-chain antibody fragment protein-IX fusion in the adenovirus capsid.

scientific article published on February 2007

Enhancement of radiation therapy by tumor necrosis factor alpha in human colon cancer using a bispecific antibody.

scientific article published on April 2003

Enzyme immunoassays using bispecific diabodies.

scientific article published on June 1997

Erratum to “Restricted Diversity of Antigen Binding Residues of Antibodies Revealed by Computational Alanine Scanning of 227 Antibody–Antigen Complexes” [J. Mol. Biol., 426, 2014, 3729–3743]

scientific article published on 11 February 2015

Evaluation of several affinity chromatographic supports for the purification of maltose-binding protein from Escherichia coli

scientific article published on 01 February 1993

Expression and immunogenicity of the V3 loop from the envelope of human immunodeficiency virus type 1 in an attenuated aroA strain of Salmonella typhimurium upon genetic coupling to two Escherichia coli carrier proteins

scientific article published in September 1993

Expression of an antibody fragment at high levels in the bacterial cytoplasm

scientific article published in July 1998

Expression of heterologous peptides at two permissive sites of the MalE protein: antigenicity and immunogenicity of foreign B-cell and T-cell epitopes

scientific article published on 01 September 1992

Expression of single-chain Fv fragments in E. coli cytoplasm. ⬇️

scientific article published on January 2009

FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer.

scientific article published on 29 September 2016

Femtosecond spectroscopy probes the folding quality of antibody fragments expressed as GFP fusions in the cytoplasm

scientific article published on 5 December 2007

Generation of an intrabody-based reagent suitable for imaging endogenous proliferating cell nuclear antigen in living cancer cells

scientific article

Homogeneous processing and presentation of a recombined T cell epitope in inbred mice of different non-MHC genetic background

scientific article published on 01 September 1996

Immune responses to hybrid maltose-binding proteins

scientific article published in January 1993

Immunodominance of a recombinant T-cell epitope depends on its molecular environment

scientific article published on 01 December 1993

Immunogenicity of viral B- and T-cell epitopes expressed in recombinant bacterial proteins.

scientific article

Impact of RNA degradation on gene expression profiles: assessment of different methods to reliably determine RNA quality.

scientific article published on 2 August 2006

In vitro folding and thermodynamic stability of an antibody fragment selected in vivo for high expression levels in Escherichia coli cytoplasm

scientific article published on 01 October 1999

In-cell intrabody selection from a diverse human library identifies C12orf4 protein as a new player in rodent mast cell degranulation

scientific journal article

Induction of T cell responses by chimeric bacterial proteins expressing several copies of a viral T cell epitope.

scientific article

Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related () Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer

scientific article published on 15 April 2019

Inhibition of DDR1-BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer

scientific article published on 9 February 2018

Letrozole sensitizes breast cancer cells to ionizing radiation

scientific article

MALDI imaging mass spectrometry and chemometric tools to discriminate highly similar colorectal cancer tissues

scientific article published on 10 October 2019

MAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy.

scientific article published on 31 May 2012

Maltodextrin-binding protein hybrids carrying epitopes from the preS2 region of hepatitis B virus: expression, antibody-binding and preliminary crystallographic studies.

scientific article published in February 1997

Modulating the immunological properties of a linear B-cell epitope by insertion into permissive sites of the MalE protein.

scientific article

Molecular and cellular targeting in the expression of foreign polypeptides in bacteria

scientific article published in February 1992

Molecular subtypes of metastatic colorectal cancer are associated with patient response to irinotecan-based therapies.

scientific article published on 8 March 2017

NMR studies on the flexibility of the poliovirus C3 linear epitope inserted into different sites of the maltose-binding protein.

scientific article

New Topoisomerase I mutations are associated with resistance to camptothecin

scientific article published on 27 May 2011

Nucleocytoplasmic shuttling of antigen in mammalian cells conferred by a soluble versus insoluble single-chain antibody fragment equipped with import/export signals

scientific article published on 01 June 2003

Overcoming the crypticity of a viral T cell determinant by insertion into a chimeric bacterial protein.

scientific article

Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells

scientific article

Potentiation of ionising radiation by targeting tumour necrosis factor alpha using a bispecific antibody in human pancreatic cancer.

scientific article published on November 2003

Prognostic significance of TRAIL-R1 and TRAIL-R3 expression in metastatic colorectal carcinomas

scientific article published on 26 August 2008

Radiocurability by targeting tumor necrosis factor-alpha using a bispecific antibody in carcinoembryonic antigen transgenic mice

scientific article published on 01 November 2007

Restricted diversity of antigen binding residues of antibodies revealed by computational alanine scanning of 227 antibody-antigen complexes

scientific article

Selection and mass spectrometry characterization of peptides targeting semiconductor surfaces

scientific article published in December 2009

Selection for intrabody solubility in mammalian cells using GFP fusions

scientific article

Solubility Characterization and Imaging of Intrabodies Using GFP-Fusions

scientific article published on January 2017

Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump.

scientific article published on 19 August 2013

Specific extracellular matrix remodeling signature of colon hepatic metastases

scientific article

Specific in vivo labeling of tyrosinated α-tubulin and measurement of microtubule dynamics using a GFP tagged, cytoplasmically expressed recombinant antibody

scientific article

Synthetic customized scFv libraries.

scientific article

Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma.

scientific article published on 15 December 2010

Tyrosine kinase syk non-enzymatic inhibitors and potential anti-allergic drug-like compounds discovered by virtual and in vitro screening

scientific article

Use of physiological information based on grayscale images to improve mass spectrometry imaging data analysis from biological tissues

scientific article published on 03 May 2019

[Antibody alternative formats: antibody fragments and new frameworks]

scientific article published on 01 December 2019

List of works by Pierre Martineau

A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm

A genetic system to elicit and monitor antipeptide antibodies without peptide synthesis.

A novel druglike spleen tyrosine kinase binder prevents anaphylactic shock when administered orally

ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan-treated metastases.

Antibody targeting of claudin-1 as a potential colorectal cancer therapy.

Casein interactions studied by the surface plasmon resonance technique.

Claudin gene expression profiles and clinical value in colorectal tumors classified according to their molecular subtype

Construction of a Synthetic Antibody Gene Library for the Selection of Intrabodies and Antibodies

Crystallization of genetically engineered active maltose-binding proteins, including an immunogenic viral epitope insertion.

Cyclophilin A as negative regulator of apoptosis by sequestering cytochrome c.

Directed evolution of single-chain Fv for cytoplasmic expression using the beta-galactosidase complementation assay results in proteins highly susceptible to protease degradation and aggregation

Efficient incorporation of a functional hyper-stable single-chain antibody fragment protein-IX fusion in the adenovirus capsid.

Enhancement of radiation therapy by tumor necrosis factor alpha in human colon cancer using a bispecific antibody.

Enzyme immunoassays using bispecific diabodies.

Erratum to “Restricted Diversity of Antigen Binding Residues of Antibodies Revealed by Computational Alanine Scanning of 227 Antibody–Antigen Complexes” [J. Mol. Biol., 426, 2014, 3729–3743]

Evaluation of several affinity chromatographic supports for the purification of maltose-binding protein from Escherichia coli

Expression and immunogenicity of the V3 loop from the envelope of human immunodeficiency virus type 1 in an attenuated aroA strain of Salmonella typhimurium upon genetic coupling to two Escherichia coli carrier proteins

Expression of an antibody fragment at high levels in the bacterial cytoplasm

Expression of heterologous peptides at two permissive sites of the MalE protein: antigenicity and immunogenicity of foreign B-cell and T-cell epitopes

Expression of single-chain Fv fragments in E. coli cytoplasm. ⬇️

FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer.

Femtosecond spectroscopy probes the folding quality of antibody fragments expressed as GFP fusions in the cytoplasm

Generation of an intrabody-based reagent suitable for imaging endogenous proliferating cell nuclear antigen in living cancer cells

Homogeneous processing and presentation of a recombined T cell epitope in inbred mice of different non-MHC genetic background

Immune responses to hybrid maltose-binding proteins

Immunodominance of a recombinant T-cell epitope depends on its molecular environment

Immunogenicity of viral B- and T-cell epitopes expressed in recombinant bacterial proteins.

Impact of RNA degradation on gene expression profiles: assessment of different methods to reliably determine RNA quality.

In vitro folding and thermodynamic stability of an antibody fragment selected in vivo for high expression levels in Escherichia coli cytoplasm

In-cell intrabody selection from a diverse human library identifies C12orf4 protein as a new player in rodent mast cell degranulation

Induction of T cell responses by chimeric bacterial proteins expressing several copies of a viral T cell epitope.

Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related () Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer

Inhibition of DDR1-BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer

Letrozole sensitizes breast cancer cells to ionizing radiation

MALDI imaging mass spectrometry and chemometric tools to discriminate highly similar colorectal cancer tissues

MAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy.

Maltodextrin-binding protein hybrids carrying epitopes from the preS2 region of hepatitis B virus: expression, antibody-binding and preliminary crystallographic studies.

Modulating the immunological properties of a linear B-cell epitope by insertion into permissive sites of the MalE protein.

Molecular and cellular targeting in the expression of foreign polypeptides in bacteria

Molecular subtypes of metastatic colorectal cancer are associated with patient response to irinotecan-based therapies.

NMR studies on the flexibility of the poliovirus C3 linear epitope inserted into different sites of the maltose-binding protein.

New Topoisomerase I mutations are associated with resistance to camptothecin

Nucleocytoplasmic shuttling of antigen in mammalian cells conferred by a soluble versus insoluble single-chain antibody fragment equipped with import/export signals

Overcoming the crypticity of a viral T cell determinant by insertion into a chimeric bacterial protein.

Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells

Potentiation of ionising radiation by targeting tumour necrosis factor alpha using a bispecific antibody in human pancreatic cancer.

Prognostic significance of TRAIL-R1 and TRAIL-R3 expression in metastatic colorectal carcinomas

Radiocurability by targeting tumor necrosis factor-alpha using a bispecific antibody in carcinoembryonic antigen transgenic mice

Restricted diversity of antigen binding residues of antibodies revealed by computational alanine scanning of 227 antibody-antigen complexes

Selection and mass spectrometry characterization of peptides targeting semiconductor surfaces

Selection for intrabody solubility in mammalian cells using GFP fusions

Solubility Characterization and Imaging of Intrabodies Using GFP-Fusions

Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump.

Specific extracellular matrix remodeling signature of colon hepatic metastases

Specific in vivo labeling of tyrosinated α-tubulin and measurement of microtubule dynamics using a GFP tagged, cytoplasmically expressed recombinant antibody

Synthetic customized scFv libraries.

Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma.

Tyrosine kinase syk non-enzymatic inhibitors and potential anti-allergic drug-like compounds discovered by virtual and in vitro screening

Use of physiological information based on grayscale images to improve mass spectrometry imaging data analysis from biological tissues

[Antibody alternative formats: antibody fragments and new frameworks]