List of works - Patrick C. Reading

A Novel Method Linking Antigen Presentation by Human Monocyte-Derived Macrophages to CD8(+) T Cell Polyfunctionality

scientific article published on 21 November 2013

A kinetic analysis of immune mediators in the lungs of mice infected with vaccinia virus and comparison with intradermal infection

scientific article published in August 2003

A role for plasmacytoid dendritic cells in the rapid IL-18-dependent activation of NK cells following HSV-1 infection

scientific article published on May 2007

A single amino acid substitution in the hemagglutinin of H3N2 subtype influenza A viruses is associated with resistance to the long pentraxin PTX3 and enhanced virulence in mice

scientific article published on 4 December 2013

A soluble chemokine-binding protein from vaccinia virus reduces virus virulence and the inflammatory response to infection.

scientific article published on February 2003

Addition of glycosylation to influenza A virus hemagglutinin modulates antibody-mediated recognition of H1N1 2009 pandemic viruses

scientific article

Age-associated cross-reactive antibody-dependent cellular cytotoxicity toward 2009 pandemic influenza A virus subtype H1N1.

scientific article

Airway Exosomes Released During Influenza Virus Infection Serve as a Key Component of the Antiviral Innate Immune Response

scientific article published on 12 May 2020

Antibodies mediate formation of neutrophil extracellular traps in the middle ear and facilitate secondary pneumococcal otitis media

scientific article

Antigenic drift of the pandemic 2009 A(H1N1) influenza virus in A ferret model

scientific article

Antiviral activity of bovine collectins against rotaviruses.

scientific article published on September 1998

Antiviral activity of the long chain pentraxin PTX3 against influenza viruses

scientific article

Bacterial lipopolysaccharide inhibits influenza virus infection of human macrophages and the consequent induction of CD8+ T cell immunity.

scientific article published on 20 August 2013

CSF3R/CD114 mediates infection-dependent transition to severe asthma

scientific article published on 09 October 2018

Cell-surface receptors on macrophages and dendritic cells for attachment and entry of influenza virus

scientific article

Changes in Gut Microbiota Prior to Influenza A Virus Infection Do Not Affect Immune Responses in Pups or Juvenile Mice

article

Changes in the hemagglutinin molecule of influenza type A (H3N2) virus associated with increased virulence for mice.

scientific article published on January 1997

Characterization of Influenza B Virus Variants with Reduced Neuraminidase Inhibitor Susceptibility

scientific article published on 24 October 2018

Characterization of substitutions in the neuraminidase of A(H7N9) influenza viruses selected following serial passage in the presence of different neuraminidase inhibitors

scientific article published on 25 May 2019

Characterization of the Localized Immune Response in the Respiratory Tract of Ferrets following Infection with Influenza A and B Viruses

scientific article

Collectin-mediated antiviral host defense of the lung: evidence from influenza virus infection of mice

scientific article published in November 1997

Complement-dependent neutralization of influenza virus by a serum mannose-binding lectin

scientific article published in March 1994

Correlation between sialic acid expression and infection of murine macrophages by different strains of influenza virus ⬇️

scientific article published on October 23, 2010

Critical role of airway macrophages in modulating disease severity during influenza virus infection of mice

scientific article

Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies

scientific article

DC-SIGN and L-SIGN Are Attachment Factors That Promote Infection of Target Cells by Human Metapneumovirus in the Presence or Absence of Cellular Glycosaminoglycans

scientific article published on 22 June 2016

Depletion of Gr-1+, but not Ly6G+, immune cells exacerbates virus replication and disease in an intranasal model of herpes simplex virus type 1 infection

scientific article published on 9 June 2010

Dermal infection with vaccinia virus reveals roles for virus proteins not seen using other inoculation routes

scientific article published in August 2002

Differential neutrophil activation in viral infections: Enhanced TLR-7/8-mediated CXCL8 release in asthma

scientific article published on 18 October 2015

Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus

scientific article

Downregulation of MHC Class I Expression by Influenza A and B Viruses

scientific article published on 29 May 2019

Endocytic function is critical for influenza A virus infection via DC-SIGN and L-SIGN.

scientific article

Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection

scientific article published on 13 November 2015

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy.

scientific article

Evidence for Viral Interference and Cross-reactive Protective Immunity Between Influenza B Virus Lineages.

scientific article published on 6 January 2018

Expression of a Functional Mx1 Protein Is Essential for the Ability of RIG-I Agonist Prophylaxis to Provide Potent and Long-Lasting Protection in a Mouse Model of Influenza A Virus Infection

scientific article published on 18 July 2022

Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude

scientific article published on 8 September 2017

Glycosylation as a target for recognition of influenza viruses by the innate immune system

scientific article published on January 2007

Glycosylation of the hemagglutinin modulates the sensitivity of H3N2 influenza viruses to innate proteins in airway secretions and virulence in mice

scientific article published on 24 February 2011

Gr-1+ cells, but not neutrophils, limit virus replication and lesion development following flank infection of mice with herpes simplex virus type-1.

scientific article published in November 2010

Host Cell Restriction Factors of Paramyxoviruses and Pneumoviruses

scientific article published on 02 December 2020

Host Cell Restriction Factors that Limit Influenza A Infection.

scientific article published on 7 December 2017

IFITM3 and type I interferons are important for the control of influenza A virus replication in murine macrophages

scientific article published on 05 November 2019

IL-18, but not IL-12, regulates NK cell activity following intranasal herpes simplex virus type 1 infection

scientific article

Increased nasopharyngeal bacterial titers and local inflammation facilitate transmission of Streptococcus pneumoniae.

scientific article

Increased susceptibility of diabetic mice to influenza virus infection: compromise of collectin-mediated host defense of the lung by glucose?

scientific article

Infants Harness the Germline against RSV.

scientific article

Infection of Mouse Macrophages by Seasonal Influenza Viruses Can Be Restricted at the Level of Virus Entry and at a Late Stage in the Virus Life Cycle

scientific article

Infectious Laryngotracheitis Virus Viral Chemokine-Binding Protein Glycoprotein G Alters Transcription of Key Inflammatory Mediators In Vitro and In Vivo

scientific article published on 25 October 2017

Influenza A virus induced bacterial otitis media is independent of virus tropism for α2,6-linked sialic acid.

scientific article published on 23 April 2013

Influenza A virus interactions with macrophages: Lessons from epithelial cells

scientific article published on 18 February 2020

Influenza in the Pacific

scientific article

Influenza virus detection: driving change in public health laboratories in the Western Pacific Region

scientific article published on 05 September 2018

Influenza virus induces bacterial and nonbacterial otitis media

scientific article published on 19 September 2011

Influenza viruses differ in ability to infect macrophages and to induce a local inflammatory response following intraperitoneal injection of mice

scientific article

Influenza-Specific Antibody-Dependent Phagocytosis ⬇️

scientific article

Influenza-induced inflammation drives pneumococcal otitis media.

scientific article published on 14 January 2013

Influenza-specific antibody-dependent cellular cytotoxicity: toward a universal influenza vaccine

scientific article

Inhibition of lectin‐mediated innate host defences in vivo modulates disease severity during influenza virus infection ⬇️

scientific article published on October 12, 2010

Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection.

scientific article

Involvement of the mannose receptor in infection of macrophages by influenza virus.

scientific article

Loss of a single N-linked glycan from the hemagglutinin of influenza virus is associated with resistance to collectins and increased virulence in mice

scientific article

MAIT cells contribute to protection against lethal influenza infection in vivo

scientific article published in Nature Communications

Macrophage receptors for influenza A virus: role of the macrophage galactose-type lectin and mannose receptor in viral entry

scientific article

Mapping the pulmonary environment of animals protected from virulent H1N1 influenza infection using the TLR-2 agonist Pam₂Cys.

scientific article

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

scientific article published on 22 March 2009

N-linked glycosylation facilitates sialic acid-independent attachment and entry of influenza A viruses into cells expressing DC-SIGN or L-SIGN

scientific article

NK cells contribute to the early clearance of HSV-1 from the lung but cannot control replication in the central nervous system following intranasal infection

scientific article published in April 2006

Nasal-associated lymphoid tissues (NALTs) support the recall but not priming of influenza virus-specific cytotoxic T cells.

scientific article published on May 2017

Neonatal pneumococcal colonisation caused by Influenza A infection alters lung function in adult mice

scientific article published on 4 March 2016

Neutralizing inhibitors in the airways of naïve ferrets do not play a major role in modulating the virulence of H3 subtype influenza A viruses

scientific article

Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

article

Neutrophils sustain effective CD8+ T-cell responses in the respiratory tract following influenza infection

article

Oseltamivir Prophylaxis Reduces Inflammation and Facilitates Establishment of Cross-Strain Protective T Cell Memory to Influenza Viruses

scientific article

Pandemic H1N1 influenza A viruses are resistant to the antiviral activities of innate immune proteins of the collectin and pentraxin superfamilies

scientific article

Pathogenesis, humoral immune responses and transmission between co-housed animals in a ferret model of human RSV infection

scientific article

Pattern recognition receptor immunomodulation of innate immunity as a strategy to limit the impact of influenza virus.

scientific article published on 3 November 2016

Pentraxins and Collectins: Friend or Foe during Pathogen Invasion?

scientific article

Playing hide and seek: how glycosylation of the influenza virus hemagglutinin can modulate the immune response to infection.

scientific article

Rapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection

scientific article published in PLoS ONE

Receptor specificity of the influenza virus hemagglutinin modulates sensitivity to soluble collectins of the innate immune system and virulence in mice

scientific article published on 21 March 2011

Resident memory CD8+ T cells in the upper respiratory tract prevent pulmonary influenza virus infection.

scientific article published on June 2017

Respiratory DC Use IFITM3 to Avoid Direct Viral Infection and Safeguard Virus-Specific CD8+ T Cell Priming

scientific article published on 23 November 2015

Responses of mouse airway epithelial cells and alveolar macrophages to virulent and avirulent strains of influenza A virus

scientific article published in April 2011

Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation. ⬇️

scientific article

Safety, immunogenicity and protection of A(H3N2) live attenuated influenza vaccines containing wild-type nucleoprotein in a ferret model

scientific article published on 19 June 2018

Seasonal influenza vaccine policies, recommendations and use in the World Health Organization's Western Pacific Region

scientific article

Serum amyloid P is a sialylated glycoprotein inhibitor of influenza A viruses

scientific article

Soluble host defense lectins in innate immunity to influenza virus

scientific article

Specific sites of N-linked glycosylation on the hemagglutinin of H1N1 subtype influenza A virus determine sensitivity to inhibitors of the innate immune system and virulence in mice

scientific article published on 18 July 2011

Standard trivalent influenza virus protein vaccination does not prime antibody-dependent cellular cytotoxicity in macaques

scientific article published on 09 October 2013

Steroid hormone synthesis by vaccinia virus suppresses the inflammatory response to infection

scientific article

TaqMan real time RT-PCR assays for detecting ferret innate and adaptive immune responses

scientific article published on 4 May 2014

The "sweet" side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation

scientific article published on January 2012

The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus

scientific article

The fate of influenza A virus after infection of human macrophages and dendritic cells

scientific article published on 15 August 2012

The first external quality assessment of isolation and identification of influenza viruses in cell culture in the Asia Pacific region, 2016.

scientific article published on 2 November 2017

The macrophage galactose-type lectin can function as an attachment and entry receptor for influenza virus

scientific article

The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense

scientific article

The role of neutrophils during mild and severe influenza virus infections of mice

scientific article

The role of neutrophils in the upper and lower respiratory tract during influenza virus infection of mice

scientific article published on August 2008

The vaccinia virus A41L protein is a soluble 30 kDa glycoprotein that affects virus virulence

scientific article published in September 2001

The vaccinia virus C12L protein inhibits mouse IL-18 and promotes virus virulence in the murine intranasal model

scientific article published on November 2002

The vaccinia virus kelch-like protein C2L affects calcium-independent adhesion to the extracellular matrix and inflammation in a murine intradermal model

scientific article published in September 2003

Unique Transcriptional Architecture in Airway Epithelial Cells and Macrophages Shapes Distinct Responses following Influenza Virus Infection Ex Vivo

scientific article published on 05 March 2019

Unraveling the role of the MOV10 RNA helicase during influenza A virus infection

scientific article published on 27 March 2019

Using bioluminescent imaging to investigate synergism between Streptococcus pneumoniae and influenza A virus in infant mice

scientific article

Vaccinia virus CrmE encodes a soluble and cell surface tumor necrosis factor receptor that contributes to virus virulence

scientific article

Vaccinia virus interleukin-18-binding protein promotes virulence by reducing gamma interferon production and natural killer and T-cell activity

scientific article

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence

scientific article

Vaccinia virus semaphorin A39R is a 50-55 kDa secreted glycoprotein that affects the outcome of infection in a murine intradermal model

scientific article published in September 2001

List of works by Patrick C. Reading

A Novel Method Linking Antigen Presentation by Human Monocyte-Derived Macrophages to CD8(+) T Cell Polyfunctionality

A kinetic analysis of immune mediators in the lungs of mice infected with vaccinia virus and comparison with intradermal infection

A role for plasmacytoid dendritic cells in the rapid IL-18-dependent activation of NK cells following HSV-1 infection

A single amino acid substitution in the hemagglutinin of H3N2 subtype influenza A viruses is associated with resistance to the long pentraxin PTX3 and enhanced virulence in mice

A soluble chemokine-binding protein from vaccinia virus reduces virus virulence and the inflammatory response to infection.

Addition of glycosylation to influenza A virus hemagglutinin modulates antibody-mediated recognition of H1N1 2009 pandemic viruses

Age-associated cross-reactive antibody-dependent cellular cytotoxicity toward 2009 pandemic influenza A virus subtype H1N1.

Airway Exosomes Released During Influenza Virus Infection Serve as a Key Component of the Antiviral Innate Immune Response

Antibodies mediate formation of neutrophil extracellular traps in the middle ear and facilitate secondary pneumococcal otitis media

Antigenic drift of the pandemic 2009 A(H1N1) influenza virus in A ferret model

Antiviral activity of bovine collectins against rotaviruses.

Antiviral activity of the long chain pentraxin PTX3 against influenza viruses

Bacterial lipopolysaccharide inhibits influenza virus infection of human macrophages and the consequent induction of CD8+ T cell immunity.

CSF3R/CD114 mediates infection-dependent transition to severe asthma

Cell-surface receptors on macrophages and dendritic cells for attachment and entry of influenza virus

Changes in Gut Microbiota Prior to Influenza A Virus Infection Do Not Affect Immune Responses in Pups or Juvenile Mice

Changes in the hemagglutinin molecule of influenza type A (H3N2) virus associated with increased virulence for mice.

Characterization of Influenza B Virus Variants with Reduced Neuraminidase Inhibitor Susceptibility

Characterization of substitutions in the neuraminidase of A(H7N9) influenza viruses selected following serial passage in the presence of different neuraminidase inhibitors

Characterization of the Localized Immune Response in the Respiratory Tract of Ferrets following Infection with Influenza A and B Viruses

Collectin-mediated antiviral host defense of the lung: evidence from influenza virus infection of mice

Complement-dependent neutralization of influenza virus by a serum mannose-binding lectin

Correlation between sialic acid expression and infection of murine macrophages by different strains of influenza virus ⬇️

Critical role of airway macrophages in modulating disease severity during influenza virus infection of mice

Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies

DC-SIGN and L-SIGN Are Attachment Factors That Promote Infection of Target Cells by Human Metapneumovirus in the Presence or Absence of Cellular Glycosaminoglycans

Depletion of Gr-1+, but not Ly6G+, immune cells exacerbates virus replication and disease in an intranasal model of herpes simplex virus type 1 infection

Dermal infection with vaccinia virus reveals roles for virus proteins not seen using other inoculation routes

Differential neutrophil activation in viral infections: Enhanced TLR-7/8-mediated CXCL8 release in asthma

Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus

Downregulation of MHC Class I Expression by Influenza A and B Viruses

Endocytic function is critical for influenza A virus infection via DC-SIGN and L-SIGN.

Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy.

Evidence for Viral Interference and Cross-reactive Protective Immunity Between Influenza B Virus Lineages.

Expression of a Functional Mx1 Protein Is Essential for the Ability of RIG-I Agonist Prophylaxis to Provide Potent and Long-Lasting Protection in a Mouse Model of Influenza A Virus Infection

Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude

Glycosylation as a target for recognition of influenza viruses by the innate immune system

Glycosylation of the hemagglutinin modulates the sensitivity of H3N2 influenza viruses to innate proteins in airway secretions and virulence in mice

Gr-1+ cells, but not neutrophils, limit virus replication and lesion development following flank infection of mice with herpes simplex virus type-1.

Host Cell Restriction Factors of Paramyxoviruses and Pneumoviruses

Host Cell Restriction Factors that Limit Influenza A Infection.

IFITM3 and type I interferons are important for the control of influenza A virus replication in murine macrophages

IL-18, but not IL-12, regulates NK cell activity following intranasal herpes simplex virus type 1 infection

Increased nasopharyngeal bacterial titers and local inflammation facilitate transmission of Streptococcus pneumoniae.

Increased susceptibility of diabetic mice to influenza virus infection: compromise of collectin-mediated host defense of the lung by glucose?

Infants Harness the Germline against RSV.

Infection of Mouse Macrophages by Seasonal Influenza Viruses Can Be Restricted at the Level of Virus Entry and at a Late Stage in the Virus Life Cycle

Infectious Laryngotracheitis Virus Viral Chemokine-Binding Protein Glycoprotein G Alters Transcription of Key Inflammatory Mediators In Vitro and In Vivo

Influenza A virus induced bacterial otitis media is independent of virus tropism for α2,6-linked sialic acid.

Influenza A virus interactions with macrophages: Lessons from epithelial cells

Influenza in the Pacific

Influenza virus detection: driving change in public health laboratories in the Western Pacific Region

Influenza virus induces bacterial and nonbacterial otitis media

Influenza viruses differ in ability to infect macrophages and to induce a local inflammatory response following intraperitoneal injection of mice

Influenza-Specific Antibody-Dependent Phagocytosis ⬇️

Influenza-induced inflammation drives pneumococcal otitis media.

Influenza-specific antibody-dependent cellular cytotoxicity: toward a universal influenza vaccine

Inhibition of lectin‐mediated innate host defences in vivo modulates disease severity during influenza virus infection ⬇️

Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection.

Involvement of the mannose receptor in infection of macrophages by influenza virus.

Loss of a single N-linked glycan from the hemagglutinin of influenza virus is associated with resistance to collectins and increased virulence in mice

MAIT cells contribute to protection against lethal influenza infection in vivo

Macrophage receptors for influenza A virus: role of the macrophage galactose-type lectin and mannose receptor in viral entry

Mapping the pulmonary environment of animals protected from virulent H1N1 influenza infection using the TLR-2 agonist Pam₂Cys.

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

N-linked glycosylation facilitates sialic acid-independent attachment and entry of influenza A viruses into cells expressing DC-SIGN or L-SIGN

NK cells contribute to the early clearance of HSV-1 from the lung but cannot control replication in the central nervous system following intranasal infection

Nasal-associated lymphoid tissues (NALTs) support the recall but not priming of influenza virus-specific cytotoxic T cells.

Neonatal pneumococcal colonisation caused by Influenza A infection alters lung function in adult mice

Neutralizing inhibitors in the airways of naïve ferrets do not play a major role in modulating the virulence of H3 subtype influenza A viruses

Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

Neutrophils sustain effective CD8+ T-cell responses in the respiratory tract following influenza infection

Oseltamivir Prophylaxis Reduces Inflammation and Facilitates Establishment of Cross-Strain Protective T Cell Memory to Influenza Viruses

Pandemic H1N1 influenza A viruses are resistant to the antiviral activities of innate immune proteins of the collectin and pentraxin superfamilies

Pathogenesis, humoral immune responses and transmission between co-housed animals in a ferret model of human RSV infection

Pattern recognition receptor immunomodulation of innate immunity as a strategy to limit the impact of influenza virus.

Pentraxins and Collectins: Friend or Foe during Pathogen Invasion?

Playing hide and seek: how glycosylation of the influenza virus hemagglutinin can modulate the immune response to infection.