Search filters

List of works by Jean M. Fletcher

A pilot study of the immunological effects of high-dose vitamin D in healthy volunteers.

scientific article

Altered metabolic pathways regulate synovial inflammation in Rheumatoid Arthritis

scientific article published on 11 November 2018

Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells

scientific article published in June 2002

CD141+ myeloid dendritic cells are enriched in healthy human liver ⬇️

scientific article published on August 19, 2013

CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis

scientific article published on 16 November 2009

CD4+ T-lymphocyte telomere length is related to fibrosis stage, clinical outcome and treatment response in chronic hepatitis C virus infection

scientific article

Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity.

scientific article

Cytomegalovirus-specific CD4+ T cells in healthy carriers are continuously driven to replicative exhaustion

scientific article published in December 2005

Cytomegalovirus‐Infected Endothelial Cells Recruit Neutrophils by the Secretion of C‐X‐C Chemokines and Transmit Virus by Direct Neutrophil‐Endothelial Cell Contact and during Neutrophil Transendothelial Migration ⬇️

scientific article published on June 1, 1998

Dose-related effects of vitamin D on immune responses in patients with clinically isolated syndrome and healthy control participants: study protocol for an exploratory randomized double- blind placebo-controlled trial

scientific article published on 27 August 2013

Enriched Cd141+ DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesis

scientific article published on 06 December 2018

Enrichment of Inflammatory IL-17 and TNF-α Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of the Immune Checkpoint Molecule, PD-1

scientific article published on 7 March 2016

Enrichment of Plasma Cells in the Peripheral Blood and Skin of Patients with Hidradenitis Suppurativa

scientific article published on 01 November 2019

Enrichment of polyfunctional IL-17 producing T cells in paradoxical psoriasis skin lesions

scientific article published on 01 November 2019

Epstein-Barr virus-specific CD8(+) T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential

scientific article published in August 2002

Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells.

scientific article

Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta

scientific article published on October 2008

Hidradenitis suppurativa is characterised by dysregulation of the Th17:Treg cell axis, which is corrected by anti-TNF therapy.

scientific article

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

scientific article

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo.

scientific article published in October 2006

IL-27 mediates the response to IFN-β therapy in multiple sclerosis patients by inhibiting Th17 cells

scientific article published on 21 March 2011

Impact of CMV and EBV seropositivity on CD8 T lymphocytes in an old population from West-Sicily.

scientific article published on 23 May 2007

In vivo and vitro in diagnosis of latex allergy at Groote Schuur Hospital

scientific article published in August 1997

Increased expression of Tbet in CD4(+) T cells from clinically isolated syndrome patients at high risk of conversion to clinically definite MS.

scientific article published on 18 June 2016

Integration of apoptosis and telomere erosion in virus-specific CD8+ T cells from blood and tonsils during primary infection.

scientific article published on 11 September 2003

Memory T cell homeostasis and senescence during aging.

scientific article

Natural killer cell lysis of cytomegalovirus (CMV)-infected cells correlates with virally induced changes in cell surface lymphocyte function-associated antigen-3 (LFA-3) expression and not with the CMV-induced down-regulation of cell surface class I

scientific article published on September 1, 1998

Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment.

scientific article published on 6 July 2018

OAS1: a multiple sclerosis susceptibility gene that influences disease severity

scientific article

Polyfunctional, Pathogenic CD161+ Th17 Lineage Cells Are Resistant to Regulatory T Cell-Mediated Suppression in the Context of Autoimmunity.

scientific article

Progressive telomere shortening of Epstein-Barr virus-specific memory T cells during HIV infection: contributor to exhaustion?

scientific article published in November 2008

Quiescence and functional reprogramming of Epstein-Barr virus (EBV)-specific CD8+ T cells during persistent infection

scientific article published on 29 March 2005

Recent Advances in Regulatory T Cell Therapy of Autoimmunity, Graft Rejection and Cancer ⬇️

scientific article published on November 1, 2010

Response to comment on the article by Allen et al. 'A pilot study of the immunological effects of high-dose vitamin D in healthy volunteers'.

scientific article published on 20 August 2012

Suppression of human alloreactive T cells by linear tetrapyrroles; relevance for transplantation.

scientific article published on 21 July 2016

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis.

scientific article published on October 2010

Targeting bioenergetics prevents CD4 T cell-mediated activation of synovial fibroblasts in rheumatoid arthritis

scientific article published on 11 February 2020

Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo

scientific article published on May 2004

The Biology of Multiple Sclerosis

The impact of telomere erosion on memory CD8+ T cells in patients with X-linked lymphoproliferative syndrome.

scientific article published on 25 April 2005

The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation

scientific article published in June 2007

The pathogenic role of dendritic cells in non-infectious anterior uveitis

scientific article published on 25 May 2018

Therapeutic use of vitamin D and its analogues in autoimmunity.

scientific article published on January 2012

Paulina is supported by:

About Paulina

Help