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List of works by Miroslaw K Gorny

A fully human antibody to gp41 selectively eliminates HIV-infected cells that transmigrated across a model human blood brain barrier

scientific article published on 20 November 2015

A human monoclonal antibody specific for the V3 loop of HIV type 1 clade E cross-reacts with other HIV type 1 clades.

scientific article

Additive Effects Characterize the Interaction of Antibodies Involved in Neutralization of the Primary Dualtropic Human Immunodeficiency Virus Type 1 Isolate 89.6

scientific article (publication date: October 2001)

Alloantibodies, autoantibodies, and immune complexes in patients with lung cancer

scientific article published on 01 January 1988

Amino acid residues of the human immunodeficiency virus type I gp120 critical for the binding of rat and human neutralizing antibodies that block the gp120-sCD4 interaction

scientific article published in September 1992

An immuno-dot blot assay for the detection of antibody to HIV

scientific article published on 01 June 1989

Anti-Human Immunodeficiency Virus Type 1 Human Monoclonal Antibodies that Bind Discontinuous Epitopes in the Viral Glycoproteins Can Identify Mimotopes from Recombinant Phage Peptide Display Libraries ⬇️

scientific article published on December 10, 1997

Anti-V2 antibody deficiency in individuals infected with HIV-1 in Cameroon

scientific article published on 14 January 2019

Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes

scientific article (publication date: 21 April 2010)

Anti-tumor antibodies in lung cancer patients. Immunofluorescence study using various indicator cells

scientific article published on January 1, 1979

Antibodies against encephalitogenic protein and myelin glycoprotein in the cerebrospinal fluid of patients with multiple sclerosis. Effect of encorton treatment on the autoantibody and immune complex levels

scientific article published on 01 January 1984

Assessment of phenotype of blood lymphocyte subsets prior and after PWM stimulation in patients with lung carcinoma

scientific article published on 01 January 1989

Assessment of specific anti-tumour immunity in lung cancer patients by means of leukocyte migration inhibition test. The role of antigenic preparations

scientific article published on 01 January 1982

Association of Diverse Genotypes and Phenotypes of Immune Cells and Immunoglobulins With the Course of HIV-1 Infection

article

Autoantibodies in lung cancer patients demonstrated on fixed tissue culture cells. An immunofluorescent study

scientific article published on 01 January 1981

Behaviour of local and systemic immunoglobulins in patients with lung cancer

scientific article published on 01 January 1975

Biophysical dissection of the antigen-antibody interaction of the broadly reactive anti-V3 human mAb 447-52D.

scientific article published on 13 September 2012

CSF antibodies to myelin basic protein and oligodendrocytes in multiple sclerosis and other neurological diseases

scientific article published on 01 June 1983

Characterization by serial deletion competition ELISAs of HIV-1 V3 loop epitopes recognized by monoclonal antibodies

scientific article published on 01 June 1996

Characterization of a discontinuous epitope of the HIV envelope protein gp120 recognized by a human monoclonal antibody using chemical modification and mass spectrometric analysis.

scientific article

Characterization of antibodies that inhibit HIV gp120 antigen processing and presentation

scientific article published on 01 September 2005

Characterization of human monoclonal antibodies selected with a hypervariable loop-deleted recombinant HIV-1(IIIB) gp120

scientific article published on 01 December 2001

Characterization of structural features and diversity of variable-region determinants of related quaternary epitopes recognized by human and rhesus macaque monoclonal antibodies possessing unusually potent neutralizing activities.

scientific article published on 10 August 2011

Chronic lymphocytic leukemia with prostate infiltration mediated by specific clonal membrane-bound IgM.

scientific article published on May 2003

Clonal analysis of human anti-V3 monoclonal antibodies selected by a V3 tetramer ⬇️

scientific article published on January 1, 2012

Comparative studies on cell-mediated immunity in experimental trichinnellosis. Macrophage migration inhibition and cell adherence around larva in vitro

scientific article published on January 1, 1975

Comparison of various radioactive payloads for a human monoclonal antibody to glycoprotein 41 for elimination of HIV-infected cells

scientific article published on 19 February 2020

Conserved and exposed epitopes on intact, native, primary human immunodeficiency virus type 1 virions of group M.

scientific article published in August 2000

Conserved structural elements in the V3 crown of HIV-1 gp120

scientific article

Cross-neutralizing activity of human anti-V3 monoclonal antibodies derived from non-B clade HIV-1 infected individuals ⬇️

scientific article published on 05 March 2013

Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1

scientific article

Crystal structure analysis of anti-V2 mAb 2158 suggests a conformational epitope involving an N-linked glycan

scientific article published on 13 September 2012

Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity

scientific article published on June 2006

Defining human immunodeficiency virus (HIV) type 1 immunotypes with six human monoclonal antibodies

scientific article published in January 2004

Different pattern of immunoglobulin gene usage by HIV-1 compared to non-HIV-1 antibodies derived from the same infected subject

scientific article

Differential induction of anti-V3 crown antibodies with cradle- and ladle-binding modes in response to HIV-1 envelope vaccination.

scientific article

Dissection of human immunodeficiency virus type 1 entry with neutralizing antibodies to gp41 fusion intermediates

scientific article

Dissociation rate of antibody-gp120 binding interactions is predictive of V3-mediated neutralization of HIV-1

scientific article published on 01 July 1994

Distinct mechanisms regulate exposure of neutralizing epitopes in the V2 and V3 loops of HIV-1 envelope

scientific article published on 27 August 2014

Effects of oligomerization on the epitopes of the human immunodeficiency virus type 1 envelope glycoproteins

scientific article published in February 2000

Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions with this chemokine receptor

scientific article published in September 1997

Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodies ⬇️

scientific article published on September 1, 1991

Evaluation of phenotype of mononuclear host cells isolated from primary tumour and peripheral blood of patients with laryngeal carcinoma.

scientific article published in January 1988

Factors determining the breadth and potency of neutralization by V3-specific human monoclonal antibodies derived from subjects infected with clade A or clade B strains of human immunodeficiency virus type 1

scientific article

Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site

scientific article published on 8 March 2018

Functional Implications of the Binding Mode of a Human Conformation-Dependent V2 Monoclonal Antibody against HIV

scientific article

Functional activities of 20 human immunodeficiency virus type 1 (HIV-1)-specific human monoclonal antibodies.

scientific article

Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL

scientific article published on 24 June 2015

Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals

scientific article

Functional studies of bispecific antibodies directed against HIV-1 and the Fc gamma I receptor type I

scientific article published on 01 January 1996

Generation of neutralizing anti-B19 parvovirus human monoclonal antibodies from patients infected with human immunodeficiency virus

scientific article published in September 1993

Global panel of HIV-1 Env reference strains for standardized assessments of vaccine-elicited neutralizing antibodies

scientific article

High-resolution crystal structure of the Fv of quaternary neutralizing epitope mAb 2909 reveals atomic details of its antigen-binding site

Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure

scientific article

Human anti-V2 monoclonal antibody that neutralizes primary but not laboratory isolates of human immunodeficiency virus type 1

scientific article (1994)

Human immunodeficiency virus (HIV) envelope binds to CXCR4 independently of CD4, and binding can be enhanced by interaction with soluble CD4 or by HIV envelope deglycosylation.

scientific article

Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection

scientific article

Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades.

scientific article

Human monoclonal antibodies to the V3 loop of HIV-1 with intra- and interclade cross-reactivity.

scientific article

Human monoclonal antibodies to the human immunodeficiency virus type 1 (HIV-1) transmembrane glycoprotein gp41 enhance HIV-1 infection in vitro

scientific article published on April 1990

Human monoclonal antibody 2909 binds to pseudovirions expressing trimers but not monomeric HIV-1 envelope proteins

scientific article

Identification of a tumor-related protein antigen in immune complexes derived from pleural effusions of patients with bronchial carcinoma

scientific article published on 01 January 1985

Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function

scientific article published on November 2014

Identification of sites within gp41 that serve as targets for antibody-dependent cellular cytotoxicity by using human monoclonal antibodies

scientific article published on 01 November 1990

Immune Correlates of Disease Progression in Linked HIV-1 Infection

article

Immunoprophylaxis against mother-to-child transmission of HIV-1

scientific article published on 18 July 2006

Immunoregulatory effect of T cell subsets on PWM-induced IgG synthesis by blood lymphocytes in lung cancer

scientific article published on 01 January 1991

Immunotypes of a quaternary site of HIV-1 vulnerability and their recognition by antibodies

scientific article

In vivo alteration of humoral responses to HIV-1 envelope glycoprotein gp120 by antibodies to the CD4-binding site of gp120.

scientific article published on 4 December 2007

Incidence of alloantibodies and immune complexes in bronchial secretions of lung cancer patients

scientific article published on 01 January 1987

Induction of neutralizing antibodies in rhesus macaques using V3 mimotope peptides.

scientific article published on 18 April 2016

Inhibition of human immunodeficiency virus type 1 gp120 presentation to CD4 T cells by antibodies specific for the CD4 binding domain of gp120

scientific article

Letter: Cytotoxicity in normal and multiple-sclerosis sera against mouse cells expressing theta-antigen ⬇️

scientific article published on December 13, 1975

Longitudinal study of primary HIV-1 isolates in drug-naïve individuals reveals the emergence of variants sensitive to anti-HIV-1 monoclonal antibodies

scientific article

Mapping of epitopes exposed on intact human immunodeficiency virus type 1 (HIV-1) virions: a new strategy for studying the immunologic relatedness of HIV-1.

scientific article

Monoclonal Antibodies Specific for the V2, V3, CD4-Binding Site, and gp41 of HIV-1 Mediate Phagocytosis in a Dose-Dependent Manner

scientific article published on 25 January 2017

Multimethod Longitudinal HIV Drug Resistance Analysis in Antiretroviral-Therapy-Naive Patients

scientific article

Near full genome characterization of HIV-1 unique recombinant forms in Cameroon reveals dominant CRF02_AG and F2 recombination patterns

scientific article published on 01 July 2019

Neutralization of HIV-1 primary isolates by polyclonal and monoclonal human antibodies

scientific article published on 01 September 1997

Oligomer-specific conformations of the human immunodeficiency virus (HIV-1) gp41 envelope glycoprotein ectodomain recognized by human monoclonal antibodies

scientific article

Passive immunization for the prevention and treatment of HIV infection

scientific article published on 01 November 1992

Passive immunization with a human immunodeficiency virus type 1-neutralizing monoclonal antibody in Hu-PBL-SCID mice: isolation of a neutralization escape variant

scientific article published in April 1998

Polymerase chain reaction-based assay for antibody-mediated neutralization of HIV-1 reveals a population of nonneutralized virus undetected by conventional p24 assay.

scientific article published in July 2000

Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication

scientific article (publication date: 2012)

Prediction of contact residues in anti-HIV neutralizing antibody by deep learning

scientific article published on 31 January 2020

Preferential use of the VH5-51 gene segment by the human immune response to code for antibodies against the V3 domain of HIV-1

scientific article published on 25 October 2008

Presentation of HIV V3 loop epitopes for enhanced antigenicity, immunogenicity and diagnostic potential

scientific article published on 01 October 1995

Prevalence of a V2 epitope in clade B primary isolates and its recognition by sera from HIV-1-infected individuals

scientific article published on 01 January 1997

Production of human monoclonal antibodies specific for conformational and linear non-V3 epitopes of gp120.

scientific article published in June 1992

Production of immunoglobulins and alloantibodies by lymphocytes from lung cancer patients

scientific article published on 01 January 1985

Radioimmunometric demonstration of immunoglobulin G on cancer cells derived from malignant pleural effusions

scientific article published on 01 January 1982

Reinterpretation of human immunodeficiency virus western blot patterns

scientific article

Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120

scientific article published on 01 January 1993

Residue 315 regulates V3 exposure and V3 antibody recognition on HIV subtype B and C viruses

article

Ro52 autoantibodies arise from self-reactive progenitors in a mother of a child with neonatal lupus.

scientific article published on 21 January 2017

Role of the V2, V3, and CD4-binding domains of GP120 in curdlan sulfate neutralization sensitivity of HIV-1 during infection of T lymphocytes.

scientific article published on December 1996

Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1

scientific article

Search for antiviral functions of potentially protective antibodies against V2 region of HIV-1

scientific article published on 23 July 2020

Serotyping of primary human immunodeficiency virus type 1 isolates from diverse geographic locations by flow cytometry.

scientific article published in June 1995

Specific immunity to HIV and other retroviral infections.

scientific article

Specific sequences commonly found in the V3 domain of HIV-1 subtype C isolates affect the overall conformation of native Env and induce a neutralization-resistant phenotype independent of V1/V2 masking

scientific article

Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses

scientific article

Structural Basis of the Cross-Reactivity of Genetically Related Human Anti-HIV-1 mAbs: Implications for Design of V3-Based Immunogens

scientific article

Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection

article

Structure determination of an anti-HIV-1 Fab 447-52D–peptide complex from an epitaxially twinned data set

scientific article

Structure-guided design and immunological characterization of immunogens presenting the HIV-1 gp120 V3 loop on a CTB scaffold.

scientific article

Synergistic Neutralization of Simian-Human Immunodeficiency Virus SHIV-vpu+by Triple and Quadruple Combinations of Human Monoclonal Antibodies and High-Titer Anti-Human Immunodeficiency Virus Type 1 Immunoglobulins ⬇️

scientific article published on April 1, 1998

Synergistic neutralization of a chimeric SIV/HIV type 1 virus with combinations of human anti-HIV type 1 envelope monoclonal antibodies or hyperimmune globulins

scientific article published in May 1997

Synergistic neutralization of human immunodeficiency virus type 1 by combinations of human monoclonal antibodies

scientific article published on June 1994

Synergy between human monoclonal antibodies to HIV extends their effective biologic activity against homologous and divergent strains

scientific article published on 01 August 1992

Synergy between human monoclonal antibodies to HIV extends their effective biologic activity against homologous and divergent strains

scientific article published on 01 April 1992

T-lymphocyte subsets and immunoglobulin concentrations in bronchoalveolar lavage of patients with sarcoidosis and high and low intensity alveolitis

scientific article published on 01 November 1985

Targeted killing of virally infected cells by radiolabeled antibodies to viral proteins

scientific article

The C108g epitope in the V2 domain of gp120 functions as a potent neutralization target when introduced into envelope proteins derived from human immunodeficiency virus type 1 primary isolates.

scientific article

The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel

scientific article

The cross-clade neutralizing activity of a human monoclonal antibody is determined by the GPGR V3 motif of HIV type 1

scientific article published on 01 November 2004

The influence of high-dose prednisone medication on autoantibody specific activity and on circulating immune complex level in cerebrospinal fluid of multiple sclerosis patients

scientific article published on 01 December 1983

The v3 loop is accessible on the surface of most human immunodeficiency virus type 1 primary isolates and serves as a neutralization epitope.

scientific article published on March 2004

Type-specific epitopes targeted by monoclonal antibodies with exceptionally potent neutralizing activities for selected strains of human immunodeficiency virus type 1 map to a common region of the V2 domain of gp120 and differ only at single positio

scientific article

V2-Specific Antibodies in HIV-1 Vaccine Research and Natural Infection: Controllers or Surrogate Markers

scientific article published on 03 August 2019

V2-Specific Antibodies in HIV-1 Vaccine Research and Natural Infection: Controllers or Surrogate Markers

scientific article published on 06 August 2019

[Bronchoalveolar immunoglobulins in sarcoidosis]

scientific article published on 01 January 1985

[Clinical evaluation of quantitative determination of immunoglobulins and complement in ulcerative colitis]

scientific article published on 01 May 1980

[Immune complex levels in the serum of patients with ulcerative colitis and neoplasms of the digestive system]

scientific article published on 01 March 1986

[Immune response of rabbit lymph nodes following implantation of xenogenous cartilage and bone into soft tissue]

scientific article published on 01 July 1974

[Letter: IgM immunocytes and gastrointestinal cancers]

scientific article

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