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List of works by Kazufumi Toume

2-methoxy-1,4-naphthoquinone isolated from Impatiens balsamina in a screening program for activity to inhibit Wnt signaling.

scientific article published on October 2010

5alpha, 8alpha-Epidioxysterol sulfate from a diatom Odontella aurita.

scientific article published in October 2002

9-Hydroxycanthin-6-one, a β-Carboline Alkaloid from Eurycoma longifolia, Is the First Wnt Signal Inhibitor through Activation of Glycogen Synthase Kinase 3β without Depending on Casein Kinase 1α.

scientific article published on 23 April 2015

A Bisindole Alkaloid with Hedgehog Signal Inhibitory Activity from the Myxomycete Perichaena chrysosperma.

scientific article published on 14 September 2010

A novel sesquiterpenoid dimer parviflorene F induces apoptosis by up-regulating the expression of TRAIL-R2 and a caspase-dependent mechanism.

scientific article published on 13 November 2007

Anticancer effect of a Kampo preparation Daikenchuto.

scientific article published on 8 April 2016

Boehmenan, a lignan from Hibiscus ficulneus, showed Wnt signal inhibitory activity

scientific article published on 22 May 2015

Cadinane sesquiterpenes from Curcuma parviflora.

scientific article published in April 2009

Calotropin: a cardenolide from calotropis gigantea that inhibits Wnt signaling by increasing casein kinase 1α in colon cancer cells.

scientific article published on 18 March 2014

Cerasoidine, a Bis-aporphine Alkaloid Isolated from Polyalthia cerasoides during Screening for Wnt Signal Inhibitors.

scientific article published on 4 August 2016

Characterization and quantification of monoterpenoids in different types of peony root and the related Paeonia species by liquid chromatography coupled with ion trap and time-of-flight mass spectrometry

scientific article published on 20 July 2016

Characterization of metabolites in Saposhnikovia divaricata root from Mongolia

scientific article published on 01 August 2020

Chromomycins A2 and A3 from marine actinomycetes with TRAIL resistance-overcoming and Wnt signal inhibitory activities

scientific article

Coculture of a Pathogenic Actinomycete and Animal Cells To Produce Nocarjamide, a Cyclic Nonapeptide with Wnt Signal-Activating Effect

scientific article published on 29 August 2018

Constituents of Pongamia pinnata isolated in a screening for activity to overcome tumor necrosis factor-related apoptosis-inducing ligand-resistance ⬇️

scientific article published on November 2010

Coronaridine, an iboga type alkaloid from Tabernaemontana divaricata, inhibits the Wnt signaling pathway by decreasing β-catenin mRNA expression.

scientific article published on 21 July 2015

Correction to: Search of anti-allodynic compounds from Plantaginis Semen, a crude drug ingredient of Kampo formula "Goshajinkigan"

scientific article published on 10 April 2020

Cryptolepine, isolated from Sida acuta, sensitizes human gastric adenocarcinoma cells to TRAIL-induced apoptosis.

scientific article published on January 2011

Cucullamide, a new putrescine bisamide from Amoora cucullata. ⬇️

scientific article published on August 2010

Cycloartane triterpenes and ingol diterpenes isolated from Euphorbia neriifolia in a screening program for death-receptor expression-enhancing activity

scientific article published on 14 June 2012

Cycloartane triterpenes isolated from Combretum quadrangulare in a screening program for death-receptor expression enhancing activity

scientific article published on 25 January 2011

Dehydrofuligoic Acid, a New Yellow Pigment Isolated from the Myxomycete Fuligo septica f. flava

article by Masami Ishibashi et al published 2010 in Heterocycles

Eudesmane-type sesquiterpenoid and guaianolides from Kandelia candel in a screening program for compounds to overcome TRAIL resistance

scientific article published on 23 July 2012

Identification of BMI1 Promoter Inhibitors from Beaumontia murtonii and Eugenia operculata.

scientific article

Iridoids isolated from Viticis Fructus inhibit paclitaxel-induced mechanical allodynia in mice

scientific article published on 20 August 2020

Isolation and structure elucidation of izuminosides A–C: a rare phenazine glycosides from Streptomyces sp. IFM 11260 ⬇️

scientific article published on February 9, 2011

Isolation of new fuzanins, carbamate-containing natural products, from Kitasatospora sp. IFM10917 ⬇️

scientific article published on 09 June 2010

Kami-shoyo-san ameliorates sociability deficits in ovariectomized mice, a putative female model of autism spectrum disorder, via facilitating dopamine D1 and GABAA receptor functions

scientific article published on 09 March 2019

Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism

scientific article published in PLoS ONE

Kamiuntanto increases prefrontal extracellular serotonin levels and ameliorates depression-like behaviors in mice

scientific article published on 30 November 2018

Metabolomic profiling of Saposhnikoviae Radix from Mongolia by LC-IT-TOF-MS/MS and multivariate statistical analysis

scientific article published on 01 October 2019

Nonactin and Related Compounds Found in a Screening Program for Wnt Signal Inhibitory Activity

Novel tryptophan metabolites, chromoazepinone A, B and C, produced by a blocked mutant of Chromobacterium violaceum, the biosynthetic implications and the biological activity of chromoazepinone A and B.

scientific article

Prenylated flavonoids and resveratrol derivatives isolated from Artocarpus communis with the ability to overcome TRAIL resistance.

scientific article published on 24 December 2014

Prenylflavonoids isolated from Artocarpus champeden with TRAIL-resistance overcoming activity.

scientific article published on 24 September 2013

Prophylactic administration of an extract from Plantaginis Semen and its major component aucubin inhibits mechanical allodynia caused by paclitaxel in mice

scientific article published on 02 January 2016

Ricinine: a pyridone alkaloid from Ricinus communis that activates the Wnt signaling pathway through casein kinase 1α.

scientific article

Scopadulciol, Isolated from Scoparia dulcis, Induces β-Catenin Degradation and Overcomes Tumor Necrosis Factor-Related Apoptosis Ligand Resistance in AGS Human Gastric Adenocarcinoma Cells

scientific article published on 20 March 2015

Screening inducers of neuronal BDNF gene transcription using primary cortical cell cultures from BDNF-luciferase transgenic mice

scientific article published on 14 August 2019

Search of anti-allodynic compounds from Plantaginis Semen, a crude drug ingredient of Kampo formula "Goshajinkigan"

scientific article published on 12 June 2019

Sesquiterpenes with TRAIL-resistance overcoming activity from Xanthium strumarium

scientific article

Xylogranin B: a potent Wnt signal inhibitory limonoid from Xylocarpus granatum.

scientific article

Yoropyrazone, a new naphthopyridazone alkaloid isolated from Streptomyces sp. IFM 11307 and evaluation of its TRAIL resistance-overcoming activity.

scientific article

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