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List of works by Joachim Størling

A Dual Systems Genetics Approach Identifies Common Genes, Networks, and Pathways for Type 1 and 2 Diabetes in Human Islets

scientific article published on 10 March 2021

A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes

scientific article

Antitumorigenic effect of proteasome inhibitors on insulinoma cells.

scientific article

Apolipoprotein CIII reduces proinflammatory cytokine-induced apoptosis in rat pancreatic islets via the Akt prosurvival pathway

scientific article published on 21 June 2011

Breast Milk-Derived Extracellular Vesicles Enriched in Exosomes From Mothers With Type 1 Diabetes Contain Aberrant Levels of microRNAs

scientific article published on 25 October 2019

CEBPA exerts a specific and biologically important proapoptotic role in pancreatic β cells through its downstream network targets

scientific article

CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients

scientific article

Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells

scientific article

Calcium- and proteasome-dependent degradation of the JNK scaffold protein islet-brain 1.

scientific article published on 24 September 2003

Candidate genes expressed in human islets and their role in the pathogenesis of type 1 diabetes.

scientific article published on October 2013

Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes

scientific article published on 18 August 2020

Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation

scientific article published on 23 March 2006

Cytokines and Pancreatic β-Cell Apoptosis

scientific article published on 20 April 2016

Cytokines and beta-cell biology: from concept to clinical translation

scientific article

Divalent Metal Transporter 1 Regulates Iron-Mediated ROS and Pancreatic β Cell Fate in Response to Cytokines

article

Do post-translational beta cell protein modifications trigger type 1 diabetes?

scientific article

Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells

scientific article published on 11 November 2005

G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction

scientific journal article

Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control

scientific article published on 20 January 2016

Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective po

scientific article published in July 2004

Hepatitis B virus suppresses the secretion of insulin-like growth factor binding protein 1 to facilitate anti-apoptotic IGF-1 effects in HepG2 cells

scientific article published on 04 July 2018

Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis

scientific article

IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line

scientific article published on 23 May 2006

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression

scientific article (publication date: 16 February 2012)

Immune-mediated beta-cell destruction in vitro and in vivo-A pivotal role for galectin-3

scientific journal article

Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes

scientific article

Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

scientific article published on 31 January 2007

Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells

scientific article

Interleukin-1 beta targeted therapy for type 2 diabetes

scientific article published on September 2009

Interleukin-targeted therapy for metabolic syndrome and type 2 diabetes

scientific article published on January 2011

JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression

scientific article

Low versus high carbohydrate diet in type 1 diabetes: A 12-week randomized open-label crossover study

scientific article published on 21 April 2019

MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage

scientific article published in PLoS ONE

Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt.

scientific article published on 25 August 2005

Pannexin-2-deficiency sensitizes pancreatic β-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo.

scientific article published on 5 April 2017

Plasma Exosome-Enriched Extracellular Vesicles From Lactating Mothers With Type 1 Diabetes Contain Aberrant Levels of miRNAs During the Postpartum Period

scientific article published on 08 October 2021

Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells

scientific article published on 26 May 2009

Protocol for a single-centre, parallel-group, randomised, controlled, superiority trial on the effects of time-restricted eating on body weight, behaviour and metabolism in individuals at high risk of type 2 diabetes: the REStricted Eating Time (RES

scientific article published on 26 August 2020

RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines

scientific article published on 14 July 2006

Skeletal muscle apolipoprotein B expression reduces muscular triglyceride accumulation

scientific article published on 27 March 2014

TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells

scientific article published on 20 November 2015

Temporal profiling of cytokine-induced genes in pancreatic β-cells by meta-analysis and network inference

scientific article published on 24 January 2014

The Fas pathway is involved in pancreatic beta cell secretory function

scholarly article

The genetic and regulatory architecture of ERBB3-type 1 diabetes susceptibility locus.

scientific article published on 5 October 2015

The imidazoline RX871024 induces death of proliferating insulin-secreting cells by activation of c-jun N-terminal kinase

scientific article published on April 2008

The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet β cells in vivo and in vitro

scientific article

TiSH--a robust and sensitive global phosphoproteomics strategy employing a combination of TiO2, SIMAC, and HILIC.

scientific article

Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis

scientific article published on 16 February 2017

Type 1 database mellitus: an inflammatory disease of the islet.

scientific article

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