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List of works by Charles Bangham

A functional CD8+ cell assay reveals individual variation in CD8+ cell antiviral efficacy and explains differences in human T-lymphotropic virus type 1 proviral load

scientific article

AIDS: the evolving story

scientific article published on 01 April 2000

Abundant tax protein expression in CD4+ T cells infected with human T-cell lymphotropic virus type I (HTLV-I) is prevented by cytotoxic T lymphocytes.

scientific article published on February 2000

Activated, HTLV-1-specific cytotoxic T-lymphocytes are found in healthy seropositives as well as in patients with tropical spastic paraparesis

scientific article

Activation of interleukin-13 expression in T cells from HTLV-1-infected individuals and in chronically infected cell lines.

scientific article published on 14 August 2003

Adult T cell leukemia/lymphoma: FoxP3(+) cells and the cell-mediated immune response to HTLV-1.

scientific article published on January 2011

An interactive computer program for the analysis of HLA class II restriction fragment patterns

scientific article

An introduction to lymphocyte and viral dynamics: the power and limitations of mathematical analysis

scientific article published in August 2003

Analysis of HTLV-I proviral load in 202 HAM/TSP patients and 243 asymptomatic HTLV-I carriers: high proviral load strongly predisposes to HAM/TSP.

scientific article published on December 1998

Analysis of substrate cleavage by recombinant protease of human T cell leukaemia virus type 1 reveals preferences and specificity of binding.

scientific article published in September 1994

Antigenic oscillations and shifting immunodominance in HIV-1 infections.

scientific article published in June 1995

Applied virology research (vol. 2): Virus variability, epidemiology and control

scholarly article by Charles R.M. Bangham published in October 1991

Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy.

scientific article published on April 2007

Aseptic meningitis and encephalitis: the role of PCR in the diagnostic laboratory

scientific article published on March 1997

Balancing the robustness and predictive performance of biomarkers.

scientific article published on 2 August 2013

CADM1/TSLC1 Identifies HTLV-1-Infected Cells and Determines Their Susceptibility to CTL-Mediated Lysis.

scientific article

CTL quality and the control of human retroviral infections

scientific article published on July 2009

Cell dynamics and immune response to BLV infection: a unifying model

scientific article published on January 2007

Cell-mediated cytotoxic response to respiratory syncytial virus in infants with bronchiolitis

scientific article

Cell-mediated immune response to human T-lymphotropic virus type I.

scientific article

Cellular immune response to HTLV-1.

scientific article

Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis

scientific article

Circulating anti-Tax cytotoxic T lymphocytes from human T-cell leukemia virus type I-infected people, with and without tropical spastic paraparesis, recognize multiple epitopes simultaneously.

scientific article published on May 1994

Clonality of HTLV-2 in natural infection

scientific article

Clonality, latency and integration of HTLV-1 in vivo.

scientific article

Conference highlights of the 15th International Conference on Human Retrovirology: HTLV and related retroviruses, 4-8 June 2011, Leuven, Gembloux, Belgium

scientific article published on 28 October 2011

Current protocols on CD-ROM

Cycles, chaos, and evolution in virus cultures: a model of defective interfering particles

scientific article published on August 1994

Cytokine response to respiratory syncytial virus stimulation of human peripheral blood mononuclear cells

scientific article published in November 1994

Cytotoxic T lymphocyte lysis of HTLV-1 infected cells is limited by weak HBZ protein expression, but non-specifically enhanced on induction of Tax expression.

scientific article

Cytotoxic T-cell abundance and virus load in human immunodeficiency virus type 1 and human T-cell leukaemia virus type 1.

scientific article

Cytotoxic T-cell response to respiratory syncytial virus in mice.

scientific article published on October 1985

Defective interfering particles and virus evolution.

scientific article published on October 1993

Defective interfering particles: effects in modulating virus growth and persistence

scientific article published in December 1990

Diagnosis of viral infections of the central nervous system: clinical interpretation of PCR results

scientific article published on February 1997

Direct sequencing of single primer PCR products: a rapid method to achieve short chromosomal walks

scientific article published on May 1993

Do T cells cause HTLV-1-associated disease?: a taxing problem.

scientific article published in May 1994

Do infectious diseases drive MHC diversity?

scientific article

Early acquisition of cytolytic function and transcriptional changes in a primary CD8+ T-cell response in vivo.

scientific article

Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial

scientific article (publication date: June 2014)

Effect of lamivudine on human T-cell leukemia virus type 1 (HTLV-1) DNA copy number, T-cell phenotype, and anti-tax cytotoxic T-cell frequency in patients with HTLV-1-associated myelopathy

scientific article

Effects of high altitude on endocrine function in the Sherpas of Nepal

scholarly article by C R Bangham et al published October 1978 in Journal of Endocrinology

Engagement of specific T-cell surface molecules regulates cytoskeletal polarization in HTLV-1-infected lymphocytes.

scientific article published on 14 April 2005

Enzymatic amplification of exogenous and endogenous retroviral sequences from DNA of patients with tropical spastic paraparesis.

scientific article

Epigenetic changes around the pX region and spontaneous HTLV-1 transcription are CTCF-independent

scientific article published on 11 December 2018

Estimating T-cell repertoire diversity: limitations of classical estimators and a new approach

scientific article published in August 2015

Estimating abundances of retroviral insertion sites from DNA fragment length data.

scientific article

Ethics and Biotechnology

scientific article published in October 1996

Evolution in a chronic RNA virus infection: selection on HTLV-I tax protein differs between healthy carriers and patients with tropical spastic paraparesis.

scientific article

Evolution of retrovirus-infected premalignant T-cell clones prior to Adult T-cell leukemia/lymphoma diagnosis

scientific article published on 05 March 2020

Evolutionary dynamics of HTLV-I.

scientific article published in May 2000

Ex vivo analysis of human T lymphotropic virus type 1-specific CD4+ cells by use of a major histocompatibility complex class II tetramer composed of a neurological disease-susceptibility allele and its immunodominant peptide

scientific article published in December 2007

Exclusion of actin microfilaments from the cell-cell contact zone in HTLV-1 infected T-lymphocyte during the establishment of a functional virological synapse

Exercise-induced asthma in Nepalese children.

scientific article

Fertility of Nepalese Sherpas at moderate altitudes: comparison with high-altitude data.

scientific article published on July 1980

First line treatment of acute and chronic ATLL with zidovudine (AZT) and interferon alpha (IFN-α): haematological and molecular responses

article

FoxP3+ regulatory T cells are distinct from leukemia cells in HTLV-1-associated adult T-cell leukemia.

scientific article published in November 2009

Fratricide among CD8(+) T lymphocytes naturally infected with human T cell lymphotropic virus type I.

scientific article

Free serum haemoglobin is associated with brain atrophy in secondary progressive multiple sclerosis

scientific article

Frequent reversible membrane damage in peripheral blood B cells in human T cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP).

scientific article published on May 2000

Functional Conservation of HTLV-1 Rex Balances the Immune Pressure for Sequence Variation in theRexGene

article

Gene activation therapy: from the BLV model to HAM/TSP patients

scientific article published on June 2009

Genetic control and dynamics of the cellular immune response to the human T-cell leukaemia virus, HTLV-I.

scientific article

Genetic variability in the extracellular matrix protein as a determinant of risk for developing HTLV-I-associated neurological disease

scientific article

Genome-wide determinants of proviral targeting, clonal abundance and expression in natural HTLV-1 infection

scientific article

Geographical distribution and disease associations of the CD45 exon 6 138G variant.

scientific article published on 15 March 2006

HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy

scientific article

HLA class I binding of HBZ determines outcome in HTLV-1 infection

scientific article

HTLV-1 Infection and Its Associated Diseases.

scientific article published on 7 May 2012

HTLV-1 clonality during chronic infection and BLV clonality during primary infection

HTLV-1 clonality in adult T-cell leukaemia and non-malignant HTLV-1 infection

scientific article published on 06 December 2013

HTLV-1 drives vigorous clonal expansion of infected CD8(+) T cells in natural infection

scientific article

HTLV-1 gene expression by individual infected clones determines susceptibility to lysis by cytotoxic T lymphocytes specific for Tax and HBZ.

scientific article published on 7 January 2014

HTLV-1 infection: role of CTL efficiency.

scientific article

HTLV-1 infection: what determines the risk of inflammatory disease?

scientific article published on 21 August 2012

HTLV-1 infections

scientific article

HTLV-1 integration into transcriptionally active genomic regions is associated with proviral expression and with HAM/TSP

scientific article

HTLV-1 propels thymic human T cell development in "human immune system" Rag2⁻/⁻ gamma c⁻/⁻ mice

scientific article

HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP.

scientific article

HTLV-1-Tax and ICAM-1 act on T-cell signal pathways to polarize the microtubule-organizing center at the virological synapse.

scientific article published on 3 June 2009

HTLV-1-associated myelopathy/tropical spastic paraparesis

scientific article published on 18 June 2015

HTLV-1-infected T cells contain a single integrated provirus in natural infection

scientific article

High activated and memory cytotoxic T-cell responses to HTLV-1 in healthy carriers and patients with tropical spastic paraparesis

scientific article published on March 1996

High circulating frequencies of tumor necrosis factor alpha- and interleukin-2-secreting human T-lymphotropic virus type 1 (HTLV-1)-specific CD4+ T cells in patients with HTLV-1-associated neurological disease

scientific article published on September 2003

High frequencies of Th1-type CD4(+) T cells specific to HTLV-1 Env and Tax proteins in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis

scientific article published on May 2002

High frequency of CD4+FoxP3+ cells in HTLV-1 infection: inverse correlation with HTLV-1-specific CTL response

scientific article published on 19 December 2007

High frequency of viral protein expression in human T cell lymphotropic virus type 1-infected peripheral blood mononuclear cells

scientific article published on November 2000

High production of interferon gamma but not interleukin-2 by human T-lymphotropic virus type I-infected peripheral blood mononuclear cells

scientific article published on August 2001

Highly active antiretroviral treatment against STLV-1 infection combining reverse transcriptase and HDAC inhibitors.

scientific article

Histone H2A monoubiquitylation and p38-MAPKs regulate immediate-early gene-like reactivation of latent retrovirus HTLV-1

article

Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection

scientific article published on 15 August 2006

How does HTLV-1 cause adult T-cell leukaemia/lymphoma (ATL)?

scientific article

How does HTLV-I persist despite a strong cell-mediated immune response?

scientific article published on 26 November 2007

Human T cell lymphotropic virus (HTLV) type-1-specific CD8+ T cells: frequency and immunodominance hierarchy.

scientific article published on 20 May 2004

Human T cell lymphotropic virus type I (HTLV-I)-specific CD4+ T cells: immunodominance hierarchy and preferential infection with HTLV-I.

scientific article published on February 2004

Human T cells expressing affinity-matured TCR display accelerated responses but fail to recognize low density of MHC-peptide antigen

scientific article

Human T-cell leukaemia virus type 1: parasitism and pathogenesis

scientific article published on October 2017

Human T-cell leukaemia virus type I and neurological disease.

scientific article

Human T-lymphotrophic virus type I and multiple sclerosis

scientific article published in June 1990

Human T-lymphotropic virus type 1 (HTLV-1): persistence and immune control

scientific article published on November 2003

Human T-lymphotropic virus type 1(HTLV-1) integration, HTLV-1-associated infective dermatitis (IDH) and the risk of Adult T cell leukaemia/lymphoma (ATLL).

scientific article published on 6 June 2011

Human T-lymphotropic virus type 1-induced CC chemokine ligand 22 maintains a high frequency of functional FoxP3+ regulatory T cells.

scientific article published on 4 June 2010

Human T-lymphotropic virus, type 1, tax protein triggers microtubule reorientation in the virological synapse

scientific article

Human T-lymphotropic virus-1 visualized at the virological synapse by electron tomography

scientific article

Human and murine cytotoxic T cells specific to respiratory syncytial virus recognize the viral nucleoprotein (N), but not the major glycoprotein (G), expressed by vaccinia virus recombinants

scientific article published in December 1986

Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

scientific article

Human immunodeficiency virus variants that escape cytotoxic T-cell recognition

scientific article (publication date: August 1992)

Identification of HTLV-1-specific CTL directed against synthetic and naturally processed peptides in HLA-B*3501 transgenic mice.

scientific article published in December 1996

Identification of long-range chromatin interactions between HTLV-1 and the host genome.

scientific article

Immune Compromise in HIV-1/HTLV-1 Coinfection With Paradoxical Resolution of CD4 Lymphocytosis During Antiretroviral Therapy: A Case Report.

scientific article published on December 2015

Immunopathogenesis of human T-cell leukemia virus type-1-associated myelopathy/tropical spastic paraparesis: recent perspectives

scientific article

In vivo T lymphocyte dynamics in humans and the impact of human T-lymphotropic virus 1 infection

scholarly article

In vivo expression of human T-lymphotropic virus type 1 basic leucine-zipper protein generates specific CD8+ and CD4+ T-lymphocyte responses that correlate with clinical outcome

scientific article

In vivo selection of T-cell receptor junctional region sequences by HLA-A2 human T-cell lymphotropic virus type 1 Tax11-19 peptide complexes

scientific article published on January 2001

Increased level of arginase activity correlates with disease severity in HIV-seropositive patients

scientific article

Integration site and clonal expansion in human chronic retroviral infection and gene therapy.

scientific article published on 31 October 2014

Interference with immune function by HTLV-1.

scientific article published in August 2004

Intradermal DNA immunization of mice against influenza A virus using the novel PowderJect system

scientific article published in February 1998

Is There a Role for HTLV-1-Specific CTL in Adult T-Cell Leukemia/Lymphoma?

scientific article published on 30 November 2011

Is human T-cell lymphotropic virus type I really silent?

scientific article

KIR2DL2 enhances protective and detrimental HLA class I-mediated immunity in chronic viral infection

scientific article

Kinetics and intracellular compartmentalization of HTLV-1 gene expression: nuclear retention of HBZ mRNAs.

scientific article published on 11 March 2011

Letters to the editor

Local suppression of T cell responses by arginase-induced L-arginine depletion in nonhealing leishmaniasis

scientific article

Long-term persistence of activated cytotoxic T lymphocytes after viral infection of the central nervous system

scientific article published on May 1998

Longer dinucleotide repeat polymorphism in matrix metalloproteinase-9 (MMP-9) gene promoter which correlates with higher HTLV-I Tax mediated transcriptional activity influences the risk of HTLV-I associated myelopathy/tropical spastic paraparesis (H

scientific article published on November 2004

Low frequency of CD94/NKG2A+ T lymphocytes in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis, but not in asymptomatic carriers

scientific article

Lymphocyte kinetics: the interpretation of labelling data

scientific article

Meeting report on the 13th International Conference on Human Retrovirology: human T-cell leukemia virus research 30 years after adult T-cell leukemia

scientific article published on 9 November 2007

Microbial Subversion of Immunity:Microbial Subversionof Immunity

scientific article published in 2007

Molecular analysis of T cell clonotypes in muscle-infiltrating lymphocytes from patients with human T lymphotropic virus type 1 polymyositis.

scientific article published on 7 October 2002

Murine cytotoxic T cells specific to respiratory syncytial virus recognize different antigenic subtypes of the virus.

scientific article published in April 1986

Naturally occurring variants of human T-cell leukemia virus type I Tax protein impair its recognition by cytotoxic T lymphocytes and the transactivation function of Tax.

scientific article published on April 1995

Nosing ahead in the cold war

scientific article published on 01 March 1990

Passively acquired antibodies to respiratory syncytial virus impair the secondary cytotoxic T-cell response in the neonatal mouse.

scientific article published in September 1986

Phosphatidylinositol 3-kinase-δ (PI3K-δ) is a potential therapeutic target in adult T-cell leukemia-lymphoma

scientific article published on 18 July 2018

Plasma proteome analysis in HTLV-1-associated myelopathy/tropical spastic paraparesis.

scientific article

Polygenic control of human T lymphotropic virus type I (HTLV-I) provirus load and the risk of HTLV-I-associated myelopathy/tropical spastic paraparesis.

scientific article published on 13 September 2002

Polymorphism in the interleukin-10 promoter affects both provirus load and the risk of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.

scientific article

Population dynamics of immune responses to persistent viruses

scientific article published in April 1996

Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

scientific article

Practical Molecular Virology.

scientific article published in June 1993

Presentation of a new H-2D(k)-restricted epitope in the Tax protein of human T-lymphotropic virus type I is enhanced by the proteasome inhibitor lactacystin

scientific article published on March 2002

Prospective study of HTLV-I infection in an initially asymptomatic cohort.

scientific article published in September 1999

Protection against influenza virus encephalitis by adoptive lymphocyte transfer.

scientific article published in May 1997

Protection against lethal influenza virus encephalitis by intranasally primed CD8+ memory T cells.

scientific article published in October 1996

Quantification of HTLV-1 clonality and TCR diversity

scientific article

Quantification of HTLV-1 reverse transcriptase activity in ATL patients treated with zidovudine and interferon-α

scientific article published on 05 May 2017

Quantification of the virus-host interaction in human T lymphotropic virus I infection.

scientific article

Rapid dissemination of human T-lymphotropic virus type 1 during primary infection in transplant recipients

scientific article

Recognition of respiratory syncytial virus fusion protein by mouse cytotoxic T cell clones and a human cytotoxic T cell line

scientific article published in January 1989

Recruitment, activation and proliferation of CD8+ memory T cells in an immunoprivileged site.

scientific article published in December 1997

Recurrent TET2 mutations in adult T cell leukemia.

scientific article published on 7 January 2014

Reduced cell turnover in lymphocytic monkeys infected by human T-lymphotropic virus type 1.

scientific article

Reducing the global burden of HTLV-1 infection: An agenda for research and action

scientific article

Retrovirus infections of the nervous system

scientific article

Retroviruses integrate into a shared, non-palindromic DNA motif.

scientific article published on 14 November 2016

Safety of long-term treatment of HAM/TSP patients with valproic acid

scientific article

Selection forces and constraints on retroviral sequence variation.

scientific article

Selective clonal persistence of human retroviruses in vivo: Radial chromatin organization, integration site, and host transcription

scientific article published on 29 April 2022

Sequence variants of human T-cell lymphotropic virus type I from patients with tropical spastic paraparesis and adult T-cell leukemia do not distinguish neurological from leukemic isolates

scientific article published on March 1990

Single-cell heterogeneity and cell-cycle-related viral gene bursts in the human leukaemia virus HTLV-1.

scientific article published on 22 September 2017

Spastic paraparesis in a patient carrying defective human T cell leukemia virus type I (HTLV-I) provirus sequences but lacking a humoral or cytotoxic T cell response to HTLV-I.

scientific article published in April 1994

Specific human cytotoxic T cells recognize B-cell lines persistently infected with respiratory syncytial virus

scientific article published on December 1986

Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton

scientific article

Strong induction of 4-1BB, a growth and survival promoting costimulatory receptor, in HTLV-1-infected cultured and patients' T cells by the viral Tax oncoprotein

scientific article published on 14 February 2008

Strongyloidiasis and infective dermatitis alter human T lymphotropic virus-1 clonality in vivo

scientific article

Susceptibility of HBZ and Tax expressing primary HTLV-1+ T cell clones to CTL lysis.

scientific article published on 6 June 2011

Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy

scientific article

T Cell Receptor Vβ Staining Identifies the Malignant Clone in Adult T cell Leukemia and Reveals Killing of Leukemia Cells by Autologous CD8+ T cells.

scientific article

T-cell epitope prediction: rescaling can mask biological variation between MHC molecules

scientific article

The HTLV-1 Virological Synapse.

scientific article

The avidity and lytic efficiency of the CTL response to HTLV-1.

scientific article published on May 2009

The dynamics of HTLV-I and the CTL response.

scientific article

The dynamics of T-cell fratricide: application of a robust approach to mathematical modelling in immunology

scientific article published in May 2003

The ethical dimensions of the biological sciences

scientific article published in April 1995

The host genomic environment of the provirus determines the abundance of HTLV-1-infected T-cell clones

scientific article

The human leukemia virus HTLV-1 alters the structure and transcription of host chromatin in cis

The human leukemia virus HTLV-1 alters the structure and transcription of host chromatin in cis.

scientific article published on 26 June 2018

The immune control and cell-to-cell spread of human T-lymphotropic virus type 1.

scientific article published on December 2003

The immune control of HTLV-1 infection: selection forces and dynamics.

scientific article published on January 2009

The immune response to HTLV-I.

scientific article published in August 2000

The immunogenicity of intracerebral virus infection depends on anatomical site.

scientific article published in January 1997

The influence of HLA class I alleles and heterozygosity on the outcome of human T cell lymphotropic virus type I infection

scientific article published on December 2000

The potential of CD127 as a prognostic and residual disease marker in chronic adult T cell leukaemia/lymphoma

The prevalence of immediate positive skin tests in Nepalese children

scientific article

The protean immune cell synapse: a supramolecular structure with many functions.

scientific article published on December 2003

The relative contributions of infectious and mitotic spread to HTLV-1 persistence

scientific article published on 17 September 2020

The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome.

scientific article published on 29 February 2016

The role of CTLs in persistent viral infection: cytolytic gene expression in CD8+ lymphocytes distinguishes between individuals with a high or low proviral load of human T cell lymphotropic virus type 1.

scientific article published in October 2004

The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma

scientific article

The role of cytotoxic T lymphocytes in human T-cell lymphotropic virus type 1 infection

scientific article published in November 2000

The transactivator gene of human T-cell leukemia virus type I is more variable within and between healthy carriers than patients with tropical spastic paraparesis

scientific article published on October 1994

Three plasma biomarkers of HTLV-1-associated myelopathy/tropical spastic paraparesis.

scientific article

Time-course of host cell transcription during the HTLV-1 transcriptional burst

scientific article published on 16 May 2022

Transgenic models of human viral and immunological disease: Current topics in microbiology and immunology, Vol. 206

scholarly article by Charles Bangham et al published November 1996 in Virus Research

Ventilatory capacity in healthy Neplasese [proceedings].

scientific article published in February 1977

Virus dissemination through the brain parenchyma without immunologic control

scientific article published in August 1997

Virus variation, escape from cytotoxic T lymphocytes and human retroviral persistence

scientific article published in June 1998

What can evolutionary theory do for infectious diseases?

scientific article published in 2003

What is required of an HIV vaccine?

scientific article published on November 1997

Why the long latent period?

scientific article published in Nature

Zidovudine plus lamivudine in Human T-Lymphotropic Virus type-I-associated myelopathy: a randomised trial

scientific article

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