List of works - Silke Appel

3-Day monocyte-derived dendritic cells stimulated with a combination of OK432, TLR7/8 ligand, and prostaglandin E2 are a promising alternative for cancer immunotherapy

scientific article published on 01 August 2018

Aberrant cell signalling in PBMCs upon IFN-α stimulation in primary Sjögren's syndrome patients associates with type I interferon signature.

scientific article published on 31 March 2018

Activation of Peroxisome Proliferator-activated Receptor Gamma Leads to Upregulation of ESE-3 Expression in Human Monocyte-derived Dendritic Cells

scientific article published on 19 December 2013

Altered phenotype and Stat1 expression in Toll-like receptor 7/8 stimulated monocyte-derived dendritic cells from patients with primary Sjögren's syndrome.

scientific article

Anti-Ro and anti-La autoantibody profiling in Norwegian patients with primary Sjögren’s syndrome using luciferase immunoprecipitation systems (LIPS)

scientific article published on 18 July 2012

Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome.

scientific article

Bromelain Treatment Leads to Maturation of Monocyte-derived Dendritic Cells but Cannot Replace PGE2 in a Cocktail of IL-1β, IL-6, TNF-α and PGE2

scientific article published on 6 July 2011

CD11c+ Dendritic Cells Rather than Langerhans Cells are Reduced in Normal Skin of Immunosuppressed Renal Transplant Recipients

scientific article published in 2014

Characterization of monocyte-derived dendritic cells from immunosuppressed renal transplant recipients with and without squamous cell carcinomas.

scientific article published on September 2013

Cotransfection of dendritic cells with RNA coding for HER-2/neu and 4-1BBL increases the induction of tumor antigen specific cytotoxic T lymphocytes

scientific article published on 6 May 2005

Current knowledge on autoantigens and autoantibodies in psoriasis

scientific article published on 22 July 2020

Current status and future perspectives of dendritic cell-based cancer immunotherapy.

scientific article published on August 2013

Dendritic cell populations in patients with self-reported food hypersensitivity ⬇️

scientific article published on May 15, 2011

Differential regulation of MHC II and invariant chain expression during maturation of monocyte-derived dendritic cells.

scientific article published on 27 February 2012

Effect of tyrosine kinase inhibition using imatinib on normal lymphohematopoietic cells.

scientific article

Effective polyethylene glycol passivation for the inhibition of surface interactions of peripheral blood mononuclear cells and platelets.

scientific article

Effects of imatinib on monocyte-derived dendritic cells are mediated by inhibition of nuclear factor-kappaB and Akt signaling pathways

scientific article

Effects of imatinib on normal hematopoiesis and immune activation.

scientific article

Epithelial-specific transcription factor ESE-3 is involved in the development of monocyte-derived DCs.

scientific article published on 27 December 2005

Expression of ESE-3 isoforms in immunogenic and tolerogenic human monocyte-derived dendritic cells

scientific article

Expression of Toll-like receptor -7 and -9 in B cell subsets from patients with primary Sjögren's syndrome

scientific article

Identification and localization of a new human myotubularin-related protein gene, mtmr8, on 8p22-p23.

scientific article

Identification of a lysosomal peptide transport system induced during dendritic cell development

scientific article

Imatinib mesylate affects the development and function of dendritic cells generated from CD34+ peripheral blood progenitor cells.

scientific article published on 22 September 2003

In vitro suppression of immune responses using monocyte-derived tolerogenic dendritic cells from patients with primary Sjögren's syndrome.

scientific article published on January 2013

Induction of adipophilin-specific cytotoxic T lymphocytes using a novel HLA-A2-binding peptide that mediates tumor cell lysis.

scientific article published on February 2004

Levels of Dendritic Cell Populations and Regulatory T Cells Vary Significantly Between Two Commonly Used Mouse Strains

scientific article published in December 2009

Levels of plasmacytoid dendritic cells and type-2 myeloid dendritic cells are reduced in peripheral blood of patients with primary Sjogren's syndrome

scientific article published on 12 November 2009

Mass cytometry analysis of blood immune cells from psoriasis patients on biological therapy

scientific article published on 23 November 2020

Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses.

scientific article

New concepts in the pathogenesis of Sjögren's syndrome.

scientific article

No association of primary Sjögren's syndrome with Fcγ receptor gene variants

scientific article published on 4 April 2013

PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways

scientific article published on 16 August 2005

Patients with Primary Sjögren's Syndrome Have Alterations in Absolute Quantities of Specific Peripheral Leucocyte Populations

scientific article

Peritumoral dermis of squamous cell carcinomas in renal transplant recipients contains less CD11c+ myeloid dendritic cells and FoxP3+ T cells compared to immunocompetent controls

scientific article

Phosphorylation of intracellular signaling molecules in peripheral blood cells from psoriasis patients on originator or biosimilar infliximab.

scientific article published on 23 December 2017

Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759.

scientific article

Potential association of muscarinic receptor 3 gene variants with primary Sjogren's syndrome

article

Processing and presentation of HLA class I and II epitopes by dendritic cells after transfection with in vitro-transcribed MUC1 RNA.

scientific article published on 23 December 2004

Quantification of Plasmacytoid Dendritic Cells and Type 1 Myeloid Dendritic Cells in Peripheral Blood of Renal Transplant Recipients With and Without Squamous Cell Carcinoma

scientific article published in 2012

Reply to 'comment on no association of primary Sjögren's syndrome with Fcγ receptor gene variants'.

scientific article published on 10 October 2013

Severe impairment of dendritic cell allostimulatory activity by Sendai virus vectors is overcome by matrix protein gene deletion

scientific article

Surface-Mediated Priming DuringIn VitroGeneration of Monocyte-Derived Dendritic Cells

scientific article published on 23 December 2014

TLR-7 and -9 Stimulation of Peripheral Blood B Cells Indicate Altered TLR Signalling in Primary Sjögren's Syndrome Patients by Increased Secretion of Cytokines

scientific article published on 29 August 2015

The 2011 Nobel Prize in Physiology or Medicine ⬇️

scientific article published on January 1, 2012

The First Dendritic Cell-Based Therapeutic Cancer Vaccine is Approved by the FDA

scientific article published on 2 November 2010

The TNF/IL-23/IL-17 axis - head-to-head trials comparing different biologics in psoriasis treatment

scientific article published on 22 July 2020

The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner

scientific article

The complexity of Sjögren's syndrome: novel aspects on pathogenesis

scientific article

Transfection of dendritic cells with in vitro-transcribed CMV RNA induces polyclonal CD8+- and CD4+-mediated CMV-specific T cell responses.

scientific article published on 10 October 2005

Type 1 Regulatory T Cells and Regulatory B Cells Induced by Tolerogenic Dendritic Cells

scientific article published on 26 March 2013

List of works by Silke Appel

3-Day monocyte-derived dendritic cells stimulated with a combination of OK432, TLR7/8 ligand, and prostaglandin E2 are a promising alternative for cancer immunotherapy

Aberrant cell signalling in PBMCs upon IFN-α stimulation in primary Sjögren's syndrome patients associates with type I interferon signature.

Activation of Peroxisome Proliferator-activated Receptor Gamma Leads to Upregulation of ESE-3 Expression in Human Monocyte-derived Dendritic Cells

Altered phenotype and Stat1 expression in Toll-like receptor 7/8 stimulated monocyte-derived dendritic cells from patients with primary Sjögren's syndrome.

Anti-Ro and anti-La autoantibody profiling in Norwegian patients with primary Sjögren’s syndrome using luciferase immunoprecipitation systems (LIPS)

Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome.

Bromelain Treatment Leads to Maturation of Monocyte-derived Dendritic Cells but Cannot Replace PGE2 in a Cocktail of IL-1β, IL-6, TNF-α and PGE2

CD11c+ Dendritic Cells Rather than Langerhans Cells are Reduced in Normal Skin of Immunosuppressed Renal Transplant Recipients

Characterization of monocyte-derived dendritic cells from immunosuppressed renal transplant recipients with and without squamous cell carcinomas.

Cotransfection of dendritic cells with RNA coding for HER-2/neu and 4-1BBL increases the induction of tumor antigen specific cytotoxic T lymphocytes

Current knowledge on autoantigens and autoantibodies in psoriasis

Current status and future perspectives of dendritic cell-based cancer immunotherapy.

Dendritic cell populations in patients with self-reported food hypersensitivity ⬇️

Differential regulation of MHC II and invariant chain expression during maturation of monocyte-derived dendritic cells.

Effect of tyrosine kinase inhibition using imatinib on normal lymphohematopoietic cells.

Effective polyethylene glycol passivation for the inhibition of surface interactions of peripheral blood mononuclear cells and platelets.

Effects of imatinib on monocyte-derived dendritic cells are mediated by inhibition of nuclear factor-kappaB and Akt signaling pathways

Effects of imatinib on normal hematopoiesis and immune activation.

Epithelial-specific transcription factor ESE-3 is involved in the development of monocyte-derived DCs.

Expression of ESE-3 isoforms in immunogenic and tolerogenic human monocyte-derived dendritic cells

Expression of Toll-like receptor -7 and -9 in B cell subsets from patients with primary Sjögren's syndrome

Identification and localization of a new human myotubularin-related protein gene, mtmr8, on 8p22-p23.

Identification of a lysosomal peptide transport system induced during dendritic cell development

Imatinib mesylate affects the development and function of dendritic cells generated from CD34+ peripheral blood progenitor cells.

In vitro suppression of immune responses using monocyte-derived tolerogenic dendritic cells from patients with primary Sjögren's syndrome.

Induction of adipophilin-specific cytotoxic T lymphocytes using a novel HLA-A2-binding peptide that mediates tumor cell lysis.

Levels of Dendritic Cell Populations and Regulatory T Cells Vary Significantly Between Two Commonly Used Mouse Strains

Levels of plasmacytoid dendritic cells and type-2 myeloid dendritic cells are reduced in peripheral blood of patients with primary Sjogren's syndrome

Mass cytometry analysis of blood immune cells from psoriasis patients on biological therapy

Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses.

New concepts in the pathogenesis of Sjögren's syndrome.

No association of primary Sjögren's syndrome with Fcγ receptor gene variants

PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways

Patients with Primary Sjögren's Syndrome Have Alterations in Absolute Quantities of Specific Peripheral Leucocyte Populations

Peritumoral dermis of squamous cell carcinomas in renal transplant recipients contains less CD11c+ myeloid dendritic cells and FoxP3+ T cells compared to immunocompetent controls

Phosphorylation of intracellular signaling molecules in peripheral blood cells from psoriasis patients on originator or biosimilar infliximab.

Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759.

Potential association of muscarinic receptor 3 gene variants with primary Sjogren's syndrome

Processing and presentation of HLA class I and II epitopes by dendritic cells after transfection with in vitro-transcribed MUC1 RNA.

Quantification of Plasmacytoid Dendritic Cells and Type 1 Myeloid Dendritic Cells in Peripheral Blood of Renal Transplant Recipients With and Without Squamous Cell Carcinoma

Reply to 'comment on no association of primary Sjögren's syndrome with Fcγ receptor gene variants'.

Severe impairment of dendritic cell allostimulatory activity by Sendai virus vectors is overcome by matrix protein gene deletion

Surface-Mediated Priming DuringIn VitroGeneration of Monocyte-Derived Dendritic Cells

TLR-7 and -9 Stimulation of Peripheral Blood B Cells Indicate Altered TLR Signalling in Primary Sjögren's Syndrome Patients by Increased Secretion of Cytokines

The 2011 Nobel Prize in Physiology or Medicine ⬇️

The First Dendritic Cell-Based Therapeutic Cancer Vaccine is Approved by the FDA

The TNF/IL-23/IL-17 axis - head-to-head trials comparing different biologics in psoriasis treatment

The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner

The complexity of Sjögren's syndrome: novel aspects on pathogenesis

Transfection of dendritic cells with in vitro-transcribed CMV RNA induces polyclonal CD8+- and CD4+-mediated CMV-specific T cell responses.

Type 1 Regulatory T Cells and Regulatory B Cells Induced by Tolerogenic Dendritic Cells