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List of works by Bianca Altvater

2B4 (CD244) signaling by recombinant antigen-specific chimeric receptors costimulates natural killer cell activation to leukemia and neuroblastoma cells

scientific article

2B4 (CD244) signaling via chimeric receptors costimulates tumor-antigen specific proliferation and in vitro expansion of human T cells

scientific article published on 10 April 2009

A high proportion of bone marrow T cells with regulatory phenotype (CD4+CD25hiFoxP3+) in Ewing sarcoma patients is associated with metastatic disease

scientific article published in August 2009

Abstract 1927: Induction of memory CD8+ T-cell responses to STEAP-1 specific peptides for immunotherapy of Ewing sarcoma

article

Abstract 2314: Different stimulation conditions affect the immune phenotype of GD2-specific chimeric antigen receptor-expressing T cells: Table 1:

article by Laurin Ochs et al published 15 July 2016 in Cancer Research

Abstract 2503: Multicellular Ewing sarcoma spheres are efficiently targeted by activated NK cells

Abstract 3974: Insulin-like growth factor-1 receptor (IGF-1R) inhibition promotes expansion of human NK cells with potent antitumor activity against Ewing sarcoma cells

Abstract 3978: Assessment of therapeutic responses of disseminated Ewing sarcoma xenografts to adoptive therapy with chimeric receptor gene-modified T cells in mice by whole body magnetic resonance imaging

article

Abstract 3980: The immunomodulatory agent L-MTP-PE induces activation and expansion of human γδ T cells capable of lysing osteosarcoma cells

Abstract 458: High proportions of CD4+ T cells among residual bone marrow T cells in childhood acute lymphoblastic leukemia are associated with favorable early responses

article

Abstract 458: Immune-inhibitory HLA-G is expressed in the tumor microenvironment of Ewing Sarcomas

Abstract 4754: Targeting of Ewing sarcoma by CAR-reengineered GD2-specific T cells

article by Sareetha Kailayangiri et al published 15 April 2011 in Cancer Research

Activated human gammadelta T cells as stimulators of specific CD8+ T-cell responses to subdominant Epstein Barr virus epitopes: potential for immunotherapy of cancer

scientific article

Activated human γδ T cells induce peptide-specific CD8+ T-cell responses to tumor-associated self-antigens

scientific article published on 18 September 2011

Anchorage-independent growth of Ewing sarcoma cells under serum-free conditions is not associated with stem-cell like phenotype and function

scientific article

CD28 co-stimulation via tumour-specific chimaeric receptors induces an incomplete activation response in Epstein-Barr virus-specific effector memory T cells

scientific article published in June 2006

Common Ewing sarcoma-associated antigens fail to induce natural T cell responses in both patients and healthy individuals

scientific article

Cytotoxic T cells transduced with chimeric anti-CD19 receptors prevent engraftment of primary lymphoblastic leukemia in vivo

Ewing sarcoma dissemination and response to T-cell therapy in mice assessed by whole-body magnetic resonance imaging

scientific article published on 09 July 2013

FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma

scientific article published on 21 June 2017

Gene-engineered varicella-zoster virus reactive CD4+ cytotoxic T cells exert tumor-specific effector function

scientific article

High proportions of CD4⁺ T cells among residual bone marrow T cells in childhood acute lymphoblastic leukemia are associated with favorable early responses

scientific article published on 10 September 2013

Insulin-like growth factor-1 receptor (IGF-1R) inhibition promotes expansion of human NK cells which maintain their potent antitumor activity against Ewing sarcoma cells.

scientific article

NK cells are dysfunctional in human chronic myelogenous leukemia before and on imatinib treatment and in BCR-ABL-positive mice.

scientific article published on 9 September 2011

Optimized human CYP4B1 in combination with the alkylator prodrug 4-ipomeanol serves as a novel suicide gene system for adoptive T-cell therapies

scientific article

Overcoming Heterogeneity of Antigen Expression for Effective CAR T Cell Targeting of Cancers

scientific article published on 26 April 2020

PD-1 checkpoint blockade in patients with relapsed AML after allogeneic stem cell transplantation

scientific article published on 28 November 2016

Phosphatidylinositol-3-kinase (PI3K)/Akt Signaling is Functionally Essential in Myxoid Liposarcoma

scientific article published on 20 February 2019

Programmed cell death ligand 1 (PD-L1) expression is not a predominant feature in Ewing sarcomas.

scientific article published on 4 September 2017

Requirement for YAP1 signaling in myxoid liposarcoma

scientific article published on 01 May 2019

SS18-SSX-Dependent YAP/TAZ Signaling in Synovial Sarcoma

scientific article published on 27 February 2019

T Bodies

Target antigen expression on a professional antigen-presenting cell induces superior proliferative antitumor T-cell responses via chimeric T-cell receptors

scientific article published on January 2006

Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G.

scientific article published on 28 October 2016

Targeting Interleukin-2 to the Bone Marrow Stroma for Therapy of Acute Myeloid Leukemia Relapsing after Allogeneic Hematopoietic Stem Cell Transplantation

The ganglioside antigen G(D2) is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting

scientific article published on 28 February 2012

Vaccination to improve the persistence of CD19CAR gene-modified T cells in relapsed pediatric acute lymphoblastic leukemia

scientific article published on 27 January 2017

Zoledronic acid negatively affects the expansion of in vitro activated human NK cells and their cytolytic interactions with Ewing sarcoma cells

scientific article

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