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List of works by Owain W. Howell

A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis.

scientific article published on October 2010

Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis

scientific article

Calorie restriction activates new adult born olfactory-bulb neurones in a ghrelin-dependent manner but acyl-ghrelin does not enhance subventricular zone neurogenesis

scientific article published on 24 June 2019

Changes in [3H]zolpidem and [3H]Ro 15-1788 binding in rat globus pallidus and substantia nigra pars reticulata following a nigrostriatal tract lesion

scientific article published on 01 April 2000

Complement activation in multiple sclerosis plaques: an immunohistochemical analysis

scientific article

Complement is activated in progressive multiple sclerosis cortical grey matter lesions

scientific article published on 22 June 2016

Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats

scientific article published on 30 October 2013

Density and pharmacology of alpha5 subunit-containing GABA(A) receptors are preserved in hippocampus of Alzheimer's disease patients

scientific article published in January 2000

Detection of Epstein-Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look

scientific article published on 25 August 2010

Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis

scientific article published on 14 October 2006

Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves

scientific journal article

Extensive grey matter pathology in the cerebellum in multiple sclerosis is linked to inflammation in the subarachnoid space

scientific article

GLRB is the third major gene of effect in hyperekplexia.

scientific article published on 25 November 2012

Inflammatory intrathecal profiles and cortical damage in multiple sclerosis

scientific article published on 8 March 2018

Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism

scientific article published on 04 March 2020

MENINGEAL INFLAMMATION AND CORTICAL DEMYELINATION IN ACUTE MULTIPLE SCLEROSIS

scientific article published on 30 November 2018

Measurement of soluble CD59 in CSF in demyelinating disease: Evidence for an intrathecal source of soluble CD59.

scientific article published in February 2018

Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology.

scientific article published in April 2007

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

scientific article published on 11 August 2011

Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis

scientific article

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis.

scientific article published on 8 November 2010

Molecular pathology of Multiple Sclerosis lesions reveals a heterogeneous expression pattern of genes involved in oligodendrogliogenesis

scientific article published on 27 March 2018

NPY augments the proliferative effect of FGF2 and increases the expression of FGFR1 on nestin positive postnatal hippocampal precursor cells, via the Y1 receptor.

scientific article published in February 2010

NPY mediates basal and seizure-induced proliferation in the subcallosal zone.

scientific article

Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier

scientific article published on 14 December 2020

Neuropeptide Y is important for basal and seizure-induced precursor cell proliferation in the hippocampus

scientific article

Neuropeptide Y stimulates neuronal precursor proliferation in the post-natal and adult dentate gyrus

scientific article published in May 2005

New hyperekplexia mutations provide insight into glycine receptor assembly, trafficking, and activation mechanisms.

scientific article published on 09 October 2013

Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis ⬇️

scientific article published on January 7, 2011

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

scientific article

The neuropathological basis of clinical progression in multiple sclerosis ⬇️

scientific article published on May 28, 2011

Tissue microarray methodology identifies complement pathway activation and dysregulation in progressive multiple sclerosis

scientific article published on 14 July 2017

Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation

scientific article

Using biomarkers to predict clinical outcomes in multiple sclerosis

scientific article published on 26 June 2019

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