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List of works by Jonathan L Bramson

11-OR: Interaction of HLA-a*0201 and west nile virus

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A double recombinant adenovirus expressing the costimulatory molecule B7-1 (murine) and human IL-2 induces complete tumor regression in a murine breast adenocarcinoma model ⬇️

scientific article published on March 1, 1998

A human type 5 adenovirus-based tuberculosis vaccine induces robust T cell responses in humans despite preexisting anti-adenovirus immunity

scientific article published on October 2013

A novel computer algorithm improves antibody epitope prediction using affinity-selected mimotopes: a case study using monoclonal antibodies against the West Nile virus E protein

scientific article published on 29 August 2008

A quantitative systems approach to identify paracrine mechanisms that locally suppress immune response to Interleukin-12 in the B16 melanoma model

scientific article

A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo

scientific article published in January 2004

AMPK β1 reduces tumor progression and improves survival in p53 null mice.

scientific article published on 24 May 2017

Activation of host antitumoral responses by cationic lipid/DNA complexes

scientific article

Adenoviral Vectors for Gene Delivery

article

Adenoviral vectors: prospects for gene delivery to the central nervous system

scientific article published in August 1999

Adenoviral-transduced dendritic cells are susceptible to suppression by T regulatory cells and promote interleukin 17 production.

scientific article published on 14 December 2010

Alterations to the frequency and function of peripheral blood monocytes and associations with chronic disease in the advanced-age, frail elderly

scientific article

An Introduction to Automated Flow Cytometry Gating Tools and Their Implementation

scientific article (publication date: 2015)

Analysis of purified wild type and mutant adenovirus particles by SILAC based quantitative proteomics

scientific article

Anti-interleukin-12 therapy protects mice in lethal endotoxemia but impairs bacterial clearance in murine Escherichia coli peritoneal sepsis

scientific article

Anti-pneumococcal deficits of monocyte-derived macrophages from the advanced-age, frail elderly and related impairments in PI3K-AKT signaling

scientific article published on 13 October 2014

Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL.

scientific article

Applying bioinformatics for antibody epitope prediction using affinity-selected mimotopes - relevance for vaccine design

scientific article

Association between HLA class I and class II alleles and the outcome of West Nile virus infection: an exploratory study

scientific article

BCMA-specific TAC receptor-engineered T cells for multiple myeloma

scholarly article by K. Bezverbnaya et al published May 2018 in Cytotherapy

CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis

scientific article published on May 2009

CD8+ T-cell expansion and maintenance after recombinant adenovirus immunization rely upon cooperation between hematopoietic and nonhematopoietic antigen-presenting cells.

scientific article published on 18 November 2010

CTL-dependent and -independent antitumor immunity is determined by the tumor not the vaccine

scientific article published on May 2004

Characterization of Proliferating Lesion-Resident Cells During All Stages of Atherosclerotic Growth

scientific article published on 15 August 2016

Characterizing complex polysera produced by antigen-specific immunization through the use of affinity-selected mimotopes

scientific article

Chimeric antigen receptor-engineered T cells as oncolytic virus carriers

scientific article published on 9 September 2015

Circulating TNF and mitochondrial DNA are major determinants of neutrophil phenotype in the advanced-age, frail elderly

scientific article published on 5 February 2015

Circulating muramyl dipeptide is negatively associated with interleukin-10 in the frail elderly.

scientific article published on February 2015

Combination therapy with interleukin-2 and wild-type p53 expressed by adenoviral vectors potentiates tumor regression in a murine model of breast cancer

scientific article

Combined mTOR inhibition and OX40 agonism enhances CD8(+) T cell memory and protective immunity produced by recombinant adenovirus vaccines

scientific article published on 20 December 2011

Combined vaccination and immunostimulatory antibodies provides durable cure of murine melanoma and induces transcriptional changes associated with positive outcome in human melanoma patients

scientific article

Combining Cancer Vaccines with Conventional Therapies

Construction of a Double Recombinant Adenovirus Vector Expressing a Heterodimeric Cytokine: In Vitro and In Vivo Production of Biologically Active Interleukin-12

article

Correction: Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway

scientific article published on 8 June 2016

Correction: Surgical Stress Abrogates Pre-Existing Protective T Cell Mediated Anti-Tumor Immunity Leading to Postoperative Cancer Recurrence.

scientific article published on 18 July 2016

Critical Negative Regulation of Type 1 T Cell Immunity and Immunopathology by Signaling Adaptor DAP12 during Intracellular Infection

scientific article published on 01 September 2007

Cutaneous antigen priming via gene gun leads to skin-selective Th2 immune-inflammatory responses

scientific article published in February 2005

DNA repair enzyme expression in chronic lymphocytic leukemia vis-à-vis nitrogen mustard drug resistance

scientific article published on 01 April 1995

De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors

scientific article published on 04 November 2020

Deciphering epitope specificities within polyserum using affinity selection of random peptides and a novel algorithm based on pattern recognition theory

scientific article published on 26 November 2008

Defining the critical hurdles in cancer immunotherapy

scientific article published on 14 December 2011

Dendritic Cell-Derived IL-12 Is Not Required for the Generation of Cytotoxic, IFN- -Secreting, CD8+ CTL In Vivo

scientific article published on 01 November 2001

Dendritic Cells Transduced with an Adenoviral Vector Encoding a Model Tumor-Associated Antigen for Tumor Vaccination ⬇️

scientific article published on July 20, 1997

Designed ankyrin repeat proteins are effective targeting elements for chimeric antigen receptors

scientific article

Detailed analysis of the CD8+ T-cell response following adenovirus vaccination

scientific article published on December 2003

Development of cell-based tuberculosis vaccines: genetically modified dendritic cell vaccine is a much more potent activator of CD4 and CD8 T cells than peptide- or protein-loaded counterparts

scientific article

Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model.

scientific article published on 14 April 2011

Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12

scientific article published on 01 October 1996

Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop

scientific article

Effect of ERCC-1 overexpression on sensitivity of Chinese hamster ovary cells to DNA damaging agents.

scientific article published on July 1993

Effect of alkyl-N-purine DNA glycosylase overexpression on cellular resistance to bifunctional alkylating agents ⬇️

scientific article published on June 29, 1995

Effects of stuffer DNA on transgene expression from helper-dependent adenovirus vectors.

scientific article

Electroporation enables plasmid vaccines to elicit CD8+ T cell responses in the absence of CD4+ T cells.

scientific article

Elevated Frequencies of Self-reactive CD8+ T Cells following Immunization with a Xenoantigen Are Due to the Presence of a Heteroclitic CD4+ T-Cell Helper Epitope

Enhanced antitumor immunity elicited by dendritic cell vaccines is a result of their ability to engage both CTL and IFN gamma-producing NK cells

scientific article published on 4 December 2007

Epitope discovery in West Nile virus infection: Identification and immune recognition of viral epitopes

scientific article (publication date: 26 February 2008)

Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway

scientific article

F.116. Unravelling the Mechanism of Xenoimmunization By Epitope Mapping

Genetic variants and susceptibility to neurological complications following West Nile virus infection

scientific article

Genetically modified dendritic cells prime autoreactive T cells through a pathway independent of CD40L and interleukin 12: implications for cancer vaccines

scientific article published on 01 June 2000

HDAC inhibition suppresses primary immune responses, enhances secondary immune responses, and abrogates autoimmunity during tumor immunotherapy

scientific article published on 8 January 2013

HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants

scientific article published on 01 July 2018

Helper-dependent adenoviral vectors containing modified fiber for improved transduction of developing and mature muscle cells

scientific article published in February 2004

IL-12 gene therapy protects mice in lethal Klebsiella pneumonia.

scientific article

IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells

scientific article published on 9 February 2011

IL-15 can signal via IL-15Rα, JNK, and NF-κB to drive RANTES production by myeloid cells

scientific article published on 23 March 2012

IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice

scientific article

Identification of CD8+ T cell epitopes in the West Nile virus polyprotein by reverse-immunology using NetCTL.

scientific article

Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells.

scientific article published on 22 July 2016

Immune biomarkers predictive of respiratory viral infection in elderly nursing home residents.

scientific article

Immunogenicity of Varicella Vaccine and Immunologic Predictors of Response in a Cohort of Elderly Nursing Home Residents.

scientific article published on 5 October 2016

Immunosenescence in the nursing home elderly

scientific article

Immunotherapy can reject intracranial tumor cells without damaging the brain despite sharing the target antigen

scientific article published on 17 March 2010

Immunotherapy-induced CD8+ T cells instigate immune suppression in the tumor.

scientific article published on 23 October 2013

In vivo interferon regulatory factor 3 tumor suppressor activity in B16 melanoma tumors

scientific article published in September 2002

Increased DNA synthesis and repair-enzyme expression in lymphocytes from patients with chronic lymphocytic leukemia resistant to nitrogen mustards.

scientific article published in April 1991

Induction of Epitope-Specific Neutralizing Antibodies against West Nile Virus

scientific article (publication date: November 2007)

Induction of an Immune-Protective T-Cell Repertoire With Diverse Genetic Coverage by a Novel Viral-Vectored Tuberculosis Vaccine in Humans

scientific article

Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.

scientific article published in February 2006

Interactions between the immune system and cancer: a brief review of non-spatial mathematical models

scientific article published on 12 March 2010

Intramuscular immunization with a monogenic plasmid DNA tuberculosis vaccine: Enhanced immunogenicity by electroporation and co-expression of GM-CSF transgene

scientific article published on 10 October 2006

Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors

scientific article published in October 1998

Kaiso depletion attenuates the growth and survival of triple negative breast cancer cells

scientific article

Lack of evidence for a high-affinity sarcosinamide carrier or a catecholamine carrier in Calu-1 lung-cancer cells, HT-29 colon-cancer cells, and DHF fibroblasts

scientific article published on January 1, 1992

Lasting Changes to Circulating Leukocytes in People with Mild SARS-CoV-2 Infections

scientific article published in 2021

Manufacturing T cells in hollow fiber membrane bioreactors changes their programming and enhances their potency

scientific article published on 09 November 2021

Maraba virus as a potent oncolytic vaccine vector

scientific article published on 25 October 2013

Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen-presenting cell properties

scientific article published on 04 August 2009

Mesenchymal stromal cells expressing ErbB-2/neu elicit protective antibreast tumor immunity in vivo, which is paradoxically suppressed by IFN-gamma and tumor necrosis factor-alpha priming

scientific article published on 5 October 2010

Modeling anti-tumor Th1 and Th2 immunity in the rejection of melanoma

scientific article published on 5 May 2010

Multi-stability and multi-instability phenomena in a mathematical model of tumor-immune-virus interactions

scientific article published on 8 April 2011

Neoadjuvant vaccination provides superior protection against tumor relapse following surgery compared with adjuvant vaccination

scientific article published on 21 April 2009

New neuronal lineage tumor antigen and therapeutic targeting thereof

scholarly article by C. Bach et al published May 2018 in Cytotherapy

Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance

scientific article published in May 1995

Novel method for differentiation between Trastuzumab and host adaptive response

scientific article published on 8 June 2011

Obstacles to effective Toll-like receptor agonist therapy for hematologic malignancies

scientific article published on January 2008

On the role of CD4+ T cells in the CD8+ T-cell response elicited by recombinant adenovirus vaccines

scientific article published on 20 March 2007

On-target off-tumor toxicity; when enhancing an NKG2D-based CAR in vitro led to severe toxicities in vivo

article

Oncolytic vesicular stomatitis virus quantitatively and qualitatively improves primary CD8(+) T-cell responses to anticancer vaccines

scientific article published on 27 August 2013

Optimizing the culture process of engineered t cells to favor long-term efficacy following adoptive immunotherapy

article

Optimizing vaccine-induced CD8(+) T-cell immunity: focus on recombinant adenovirus vectors

scientific article published on September 2011

Persistence of transgene expression influences CD8+ T-cell expansion and maintenance following immunization with recombinant adenovirus

scientific article published on 16 September 2009

Poly(ADP-ribose) polymerase can bind melphalan damaged DNA

scientific article published on 01 November 1993

Potentiating cancer immunotherapy using an oncolytic virus

scientific article

Potentiation of chlorambucil toxicity in B-CLL lymphocytes using the DNA synthesis inhibitors aphidicolin and 1-beta-D-arabinofuranosylcytosine

scientific article published in June 1995

Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus dissemination

scientific article published in October 1997

Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials

article

Privileged Antigen Presentation in Splenic B Cell Follicles Maximizes T Cell Responses in Prime-Boost Vaccination.

scientific article

Processing of tumor antigen differentially impacts the development of helper and effector CD4+ T-cell responses

scientific article

Protection from endotoxemia by adenoviral-mediated gene transfer of human bactericidal/permeability-increasing protein

scientific article published on 22 September 2003

Recent advances in the development of adenovirus- and poxvirus-vectored tuberculosis vaccines.

scientific article

Recombinant Adenovirus Vaccines Can Successfully Elicit CD8+ T Cell Immunity under Conditions of Extreme Leukopenia

article published in 2006

Recombinant vesicular stomatitis virus transduction of dendritic cells enhances their ability to prime innate and adaptive antitumor immunity

scientific article

Role of dendritic cell-derived cytokines in immune regulation.

scientific article

Semliki forest virus and Kunjin virus RNA replicons elicit comparable cellular immunity but distinct humoral immunity

scientific article

Serum C-Reactive Protein and Congestive Heart Failure as Significant Predictors of Herpes Zoster Vaccine Response in Elderly Nursing Home Residents

scientific article published on July 2017

Super-activated interferon-regulatory factors can enhance plasmid immunization

article

Surface phenotype and functionality of WNV specific T cells differ with age and disease severity

scientific article

Surgical Stress Abrogates Pre-Existing Protective T Cell Mediated Anti-Tumor Immunity Leading to Postoperative Cancer Recurrence

scientific article (publication date: 2016)

T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice

scientific article published on 30 June 2015

T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes

scientific article published on 30 April 2014

T-Cell Phenotypes Predictive of Frailty and Mortality in Elderly Nursing Home Residents

scientific article published on 24 October 2016

T-cell immunity generated by recombinant adenovirus vaccines

scientific article published on June 2007

TGFβ Programs Central Memory Differentiation in Ex Vivo-Stimulated Human T Cells

scientific article published on 15 July 2019

TNF-alpha is a critical negative regulator of type 1 immune activation during intracellular bacterial infection

scientific article

The CD8+ T cell population elicited by recombinant adenovirus displays a novel partially exhausted phenotype associated with prolonged antigen presentation that nonetheless provides long-term immunity

scientific article published in January 2006

The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity

scientific article published in Nature Communications

The efficacy of electroporated plasmid vaccines correlates with long-term antigen production in vivo

scientific article published in June 2004

The efficacy of genetic vaccination is dependent upon the nature of the vector system and antigen

scientific article

The magnitude of the CD8+ T cell response produced by recombinant virus vectors is a function of both the antigen and the vector

scientific article published in November 2007

The memory T cell response to West Nile virus in symptomatic humans following natural infection is not influenced by age and is dominated by a restricted set of CD8+ T cell epitopes

scientific article published on July 2008

The polyfunctionality of human memory CD8+ T cells elicited by acute and chronic virus infections is not influenced by age

scientific article

The use of adenoviral vectors for gene therapy and gene transfer in vivo ⬇️

scientific article published on October 1, 1995

Tri-functional T cell receptor antigen coupler (Tri-TAC): a novel method to direct T cells against tumors

scientific article published on 6 November 2014

Tumor protection following vaccination with low doses of lentivirally transduced DCs expressing the self-antigen erbB2.

scientific article published on 8 January 2008

Tumor-targeting domains for chimeric antigen receptor T cells

scientific article published on January 2017

Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity

scientific article published on 18 December 2018

Type I IFN signaling on dendritic cells is required for NK cell-mediated anti-tumor immunity

scientific article published on 5 March 2015

Vaccination-induced autoimmune vitiligo is a consequence of secondary trauma to the skin

scientific article published in February 2004

Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus

scientific article

Viral Engineering of Chimeric Antigen Receptor Expression on Murine and Human T Lymphocytes

scientific article published on January 2016

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