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List of works by Yoshiyuki Hari

2',4'-BNA bearing a 2-pyridine nucleobase for CG base pair recognition in the parallel motif triplex DNA.

scientific article published on 21 July 2010

2',4'-BNA bearing a chiral guanidinopyrrolidine-containing nucleobase with potent ability to recognize the CG base pair in a parallel-motif DNA triplex

scientific article published on 01 August 2013

2'-C,4'-C-Ethyleneoxy-Bridged 2'-Deoxyribonucleic Acids (EoDNAs) with Thymine Nucleobases: Synthesis, Duplex-Forming Ability, and Enzymatic Stability

scientific article published on 01 January 2019

2'-O,4'-C-methylene bridged nucleic acid modification promotes pyrimidine motif triplex DNA formation at physiological pH: thermodynamic and kinetic studies.

scientific article published on 16 October 2000

2'-O,4'-C-methyleneoxymethylene bridged nucleic acids (2',4'-BNA(COC))

scientific article published on 01 January 2011

A 4-[(3R,4R)-dihydroxypyrrolidino]pyrimidin-2-one nucleobase for a CG base pair in triplex DNA

scientific article published on 09 March 2011

A bridged nucleic acid, 2',4'-BNA COC: synthesis of fully modified oligonucleotides bearing thymine, 5-methylcytosine, adenine and guanine 2',4'-BNA COC monomers and RNA-selective nucleic-acid recognition

scientific article published on 9 January 2009

Amido‐Bridged Nucleic Acids (AmNAs): Synthesis, Duplex Stability, Nuclease Resistance, and in Vitro Antisense Potency ⬇️

scientific article published on October 18, 2012

Development of artificial nucleic acid that recognizes a CG base pair in triplex DNA formation

scientific article

Effect of an N-substituent in sulfonamide-bridged nucleic acid (SuNA) on hybridization ability and duplex structure

scientific article

Effective syntheses of 2',4'-BNANC monomers bearing adenine, guanine, thymine, and 5-methylcytosine, and the properties of oligonucleotides fully modified with 2',4'-BNANC

scientific article published on 22 February 2019

Facile two-step synthesis of 3-substituted indazoles using diazo(trimethylsilyl)methylmagnesium bromide.

scientific article

Guanidine bridged nucleic acid (GuNA): an effect of a cationic bridged nucleic acid on DNA binding affinity.

scientific article

Kinetic study of the binding of triplex-forming oligonucleotides containing partial cationic modifications to double-stranded DNA.

scientific article published on 17 May 2014

Optimization of the pyridyl nucleobase scaffold for polymerase recognition and unnatural base pair replication

scientific article

Photoredox-Catalyzed Deformylative 1,4-Addition of 2'-Deoxy-5'- O-phthalimidonucleosides for Synthesis of 5'-Carba Analogs of Nucleoside 5'-Phosphates

scientific article published on 05 September 2018

Preparation and properties of 2',5'-linked oligonucleotide analogues containing 3'-O,4'-C-methyleneribonucleosides

scientific article published on 01 February 1999

Recognition of T.A interruption by 2',4'-BNAs bearing heteroaromatic nucleobases through parallel motif triplex formation

scientific article published on 25 December 2007

Stability and polymerase recognition of pyridine nucleobase analogues: role of minor-groove H-bond acceptors

scientific article published on 01 November 2006

Stable oligonucleotide-directed triplex formation at target sites with CG interruptions: strong sequence-specific recognition by 2',4'-bridged nucleic-acid-containing 2-pyridones under physiological conditions.

scientific article

Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.

scientific article published on 2 January 2016

Sulfonamide-bridged nucleic acid: synthesis, high RNA selective hybridization, and high nuclease resistance

scientific article published on 24 October 2014

Synthesis and Properties of a Bridged Nucleic Acid with a Perhydro-1,2-oxazin-3-one Ring ⬇️

scientific article published on November 15, 2011

Synthesis and Properties of the 5-Methyluridine Derivative of 3,4-Dihydro-2H-pyran-Bridged Nucleic Acid (DpNA).

scientific article

Synthesis and base-pairing properties of C-nucleotides having 1-substituted 1H-1,2,3-triazoles

scientific article published on 20 April 2009

Synthesis and duplex-forming ability of oligonucleotides containing 4'-carboxythymidine analogs.

scientific article

Synthesis and hybridizing properties of isoDNAs including 3'-O,4'-C-ethyleneoxy-bridged 5-methyluridine derivatives

scientific article published on 26 May 2018

Synthesis and properties of 2'-O,4'-C-ethyleneoxy bridged 5-methyluridine

scientific article published on 01 July 2013

Synthesis and properties of novel 2'-C,4'-C-ethyleneoxy-bridged 2'-deoxyribonucleic acids with exocyclic methylene groups.

scientific article

Synthesis and properties of thymidines with six-membered amide bridge.

scientific article published on 27 April 2013

Synthesis and thermal stabilities of oligonucleotides containing 2'-O,4'-C-methylene bridged nucleic acid with a phenoxazine base.

scientific article published on 18 September 2017

Synthesis and triplex-forming ability of 2',4'-BNAs bearing imidazoles as a nucleobase

scientific article published on 01 July 2005

Synthesis and triplex-forming ability of oligonucleotides bearing 1-substituted 1H-1,2,3-triazole nucleobases.

scientific article

Synthesis of 2'-C,4'-C-Methyleneoxy-Bridged Thymidine Derivatives and Properties of Modified Oligonucleotides

scientific article published on 10 October 2019

Synthesis of Oligonucleotides Containing 2'-N-alkylaminocarbonyl-2'-amino-LNA (2'-urea-LNA) Moieties Using Post-Synthetic Modification Strategy

scientific article published on 15 January 2020

Synthesis of oligonucleotides containing N,N-disubstituted 3-deazacytosine nucleobases by post-elongation modification and their triplex-forming ability with double-stranded DNA.

scientific article published on 06 October 2014

Synthesis of the Methyl Analog of 2'-O,4'-C-Ethylene-Bridged 5-Methyluridine via Intramolecular Radical Cyclization and Properties of Modified Oligonucleotides

scientific article published on 05 July 2019

Synthesis, duplex-forming ability, enzymatic stability, and in vitro antisense potency of oligonucleotides including 2'-C,4'-C-ethyleneoxy-bridged thymidine derivatives

scientific article published on 01 May 2017

The effects of unnatural base pairs and mispairs on DNA duplex stability and solvation.

scientific article published on 10 June 2009

Triazole- and Tetrazole-Bridged Nucleic Acids: Synthesis, Duplex Stability, Nuclease Resistance, and in Vitro and in Vivo Antisense Potency.

scientific article

Triplex Formation Involving 2′-O,4′-C-Methylene Bridged Nucleic Acid (2′,4′-BNA) with 2-Pyridone Base Analogue: Efficient and Selective Recognition of C:G Interruption ⬇️

scientific article published on May 1, 2003

Triplex- and Duplex-Forming Abilities of Oligonucleotides Containing 2'-Deoxy-5-trifluoromethyluridine and 2'-Deoxy-5-trifluoromethylcytidine.

scientific article published in January 2017

Triplex-forming ability of oligonucleotides containing 1-aryl-1,2,3-triazole nucleobases linked via a two atom-length spacer

scientific article published on 31 May 2013

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