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List of works by Danny M. Hatters

A biosensor of SRC family kinase conformation by exposable tetracysteine useful for cell-based screening.

scientific article published on 15 May 2014

A biosensor-based framework to measure latent proteostasis capacity

scientific article published on 18 January 2018

A platform to view huntingtin exon 1 aggregation flux in the cell reveals divergent influences from chaperones hsp40 and hsp70.

scientific article

A thiol probe for measuring unfolded protein load and proteostasis in cells.

scientific article published on 7 September 2017

AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding

scientific article published on January 2012

Amino-terminal domain stability mediates apolipoprotein E aggregation into neurotoxic fibrils

scientific article

Apolipoprotein E structure: insights into function.

scientific article published on 3 July 2006

Apolipoprotein E4 forms a molten globule. A potential basis for its association with disease.

scientific article published on 21 October 2002

Application of flow cytometry to analyze intracellular location and trafficking of cargo in cell populations.

scientific article

Arginine in C9ORF72 Dipolypeptides Mediates Promiscuous Proteome Binding and Multiple Modes of Toxicity

scientific article published on 21 February 2020

Conformational detection of prion protein with biarsenical labeling and FlAsH fluorescence

scientific article published on 25 January 2009

Conformational dynamics and self-association of intrinsically disordered Huntingtin exon 1 in cells

scientific article

Diagnostics for amyloid fibril formation: where to begin?

scientific article

Disease-Associated Polyglutamine Stretches in Monomeric Huntingtin Adopt a Compact Structure

scientific article

Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions

scientific article

Engineering conformational destabilization into mouse apolipoprotein E. A model for a unique property of human apolipoprotein E4.

scientific article published on 11 May 2005

Fibrillar amyloid protein present in atheroma activates CD36 signal transduction.

scientific article published on 29 December 2003

Hidden information on protein function in censuses of proteome foldedness

scientific article published on 14 April 2022

High-throughput quantitation of intracellular trafficking and organelle disruption by flow cytometry.

scientific article published on 11 March 2014

Human apolipoprotein C-II forms twisted amyloid ribbons and closed loops

scientific article published in July 2000

Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis

scientific article

Identifying polyglutamine protein species in situ that best predict neurodegeneration

scientific article published on 30 October 2011

Immiscible inclusion bodies formed by polyglutamine and poly(glycine-alanine) are enriched with distinct proteomes but converge in proteins that are risk factors for disease and involved in protein degradation

scientific article published on 28 August 2020

Insight on the molecular envelope of lipid-bound apolipoprotein E from electron paramagnetic resonance spectroscopy.

scientific article published on 24 December 2008

Macromolecular crowding accelerates amyloid formation by human apolipoprotein C-II.

scientific article published on 18 December 2001

Misfolded polyglutamine, polyalanine, and superoxide dismutase 1 aggregate via distinct pathways in the cell

scientific article published on 14 January 2014

Model of biologically active apolipoprotein E bound to dipalmitoylphosphatidylcholine

scientific article published on 8 November 2005

Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal

scientific article published on 01 January 2020

Modulation of apolipoprotein E structure by domain interaction: differences in lipid-bound and lipid-free forms

scientific article published on 01 August 2005

N-Terminal Fragments of Huntingtin Longer than Residue 170 form Visible Aggregates Independently to Polyglutamine Expansion.

scientific article

Nascent mutant Huntingtin exon 1 chains do not stall on ribosomes during translation but aggregates do recruit machinery involved in ribosome quality control and RNA

scientific article published on 31 July 2020

Phospholipid complexation and association with apolipoprotein C-II: insights from mass spectrometry.

scientific article published on December 2003

Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation.

scientific article published on 16 November 2015

Polyglutamine aggregation in Huntington and related diseases.

scientific article published on January 2012

Protein aggregation in cell biology: An aggregomics perspective of health and disease

scientific article published on 10 May 2018

Protein folding: Illuminating chaperone activity

scientific article published in March 2017

Putting huntingtin "aggregation" in view with windows into the cellular milieu.

scientific article published on January 2012

SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation

scientific article

Sedimentation analysis of novel DNA structures formed by homo-oligonucleotides.

scientific article

SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation

scientific article published on 17 June 2015

Simultaneous binding of the anti-cancer IgM monoclonal antibody PAT-SM6 to low density lipoproteins and GRP78

scientific article

Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation

scientific article

Structural insights into the multifunctionality of rabies virus P3 protein ⬇️

scientific article published on 29 March 2023

Sub-micellar phospholipid accelerates amyloid formation by apolipoprotein C-II.

scientific article

Tadpole-like Conformations of Huntingtin Exon 1 Are Characterized by Conformational Heterogeneity that Persists regardless of Polyglutamine Length

scientific article published on 05 April 2018

The Asian Biophysics Association-supporting biophysics in the greater Asia region.

scientific article published on 17 May 2019

The allosteric mechanism induced by protein kinase A (PKA) phosphorylation of dematin (band 4.9)

scientific article

The allosteric mechanism induced by protein kinase A (PKA) phosphorylation of dematin (band 4.9).

scientific article published on July 2015

The anti-cancer IgM monoclonal antibody PAT-SM6 binds with high avidity to the unfolded protein response regulator GRP78.

scientific article

The circularization of amyloid fibrils formed by apolipoprotein C-II.

scientific article

Tracking mutant huntingtin aggregation kinetics in cells reveals three major populations that include an invariant oligomer pool.

scientific article

Tracking protein aggregation and mislocalization in cells with flow cytometry

scientific article

Transcriptional profiles for distinct aggregation states of mutant Huntingtin exon 1 protein unmask new Huntington's disease pathways

scientific article

Tyrosine 416 is phosphorylated in the closed, repressed conformation of c-Src

scientific article

VLDL lipolysis products increase VLDL fluidity and convert apolipoprotein E4 into a more expanded conformation.

scientific article

Walking the tightrope: proteostasis and neurodegenerative disease

scientific article published on 12 February 2016

Widespread remodeling of proteome solubility in response to different protein homeostasis stresses

scientific article published on 21 January 2020

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